Clinical trials: Developmental Language Disorder and Language Impairment
Developmental Language Disorder, Speech Sound Disorder
A Framework For Linking Sequential Pattern Rules in DLD: Perception in Toddlers
This broad aim of this clinical study is to assess the hypothesis that morphological and phonological deficits are linked by a broader deficit in sequential pattern learning.
- Conditions
- Developmental Language Disorder, Speech Sound Disorder, Specific Language Impairment
- Trial name
- NCT04531514
- Testing
- Sensitivity to phonological rules & referents OR: Toddlers, Sensitivity to phonological rules & referents FR: Toddlers
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Autism Spectrum Disorder, Attention Deficit Disorder With Hyperactivity (ADHD)
Pai.ACT: AI-Driven ACT Chatbot for Mental Health Triage and Service Evaluation
Parents of children with special needs in Hong Kong often face limited psychological support, which can negatively impact the child rehabilitation process and the well-being of parent-child relationships.
- Conditions
- Autism Spectrum Disorder, Attention Deficit Disorder With Hyperactivity (ADHD), Neurodevelopmental Disorder (Diagnosis), Dyslexia
- Trial name
- NCT06808555
- Testing
- Pai.ACT Group, Control Group
- Where
- 20 sites in Hong Kong
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Stuttering
Shaping Motor Neural Functioning of Developmental Stuttering to Improve Fluency
Developmental stuttering (DS) is a motor/speech disorder, characterized by specific alterations in the functioning of brain circuits.
- Trial name
- NCT05306782
- Testing
- transcranial Electrical Stimulation, Speech Therapy
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Developmental Language Disorder and Language Impairment
Efficacy of Let's Know! First Grade
Oral language skills are vital for reading comprehension. Some children, however, are at increased risk for reading comprehension difficulties due to underlying oral language deficits.
- Trial name
- NCT06945289
- Testing
- Let's Know!
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Dyslexia
Maturation of Auditory Processing in Children With Dyslexia Compared to Average-reading Children
The hypothesis of central auditory processing disorders has been advanced to explain the anomalies of the grapheme/phoneme combination in some dyslexia.
- Trial name
- ASTRAUCOLE (NCT02345876)
- Testing
- no intervention
- Where
- 3 sites in France
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Stuttering, Developmental, Aphasia, Primary Progressive
Investigating Speech Sequencing in Neurotypical Speakers and Persons With Disordered Speech
Persistent developmental stuttering affects more than three million people in the United States, and it can have profound adverse effects on quality of life.
- Trial name
- NCT05437159
- Testing
- Learning of non-native phoneme combinations: 6 training sessions, Learning of non-native phoneme combinations: 1 training session, Learning of novel multisyllabic nonwords
- Where
- 3 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Developmental Language Disorders, Language Development
Understanding the Predictive Factors and the Neurocognitive Basis of Developmental Language Disorder
For most children, language acquisition might appear like an effortless phenomenon, mostly arising from informal daily interaction with their surrounding people.
- Trial name
- NCT04253600
- Testing
- Risk profile screening questionnaire, Investigation of the neural correlates of DLD using Magnetic Resonance Imagery (MRI), Online investigation of predictive factors associated with DLD and LANCOM app development
- Where
- 2 sites in Belgium
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Healthy, Speech Disorders
Development of Normative Ultrasound Databases of Tongue Surface Configuration
Our past ultrasound research has indicated a need for baseline normative tongue data against which to compare our disordered speech populations.
- Trial name
- NCT00001218
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Developmental Reading Disorder, Dyslexia
Developmental Dyslexia and Functional Maturation of Auditory Cortex
Developmental dyslexia is a frequent learning disability. The aim of this study is to compare auditory evoked cortical responses to syllables and tones in developmental dyslexia and controls (paired with age, gender).
- Trial name
- DYS-AUT (NCT00245804)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Speech and Language Disorder, Speech Therapy
Providing Speech Therapy Awareness in Private Schools
There has been limited research in the area of speech and language therapy awareness in Pakistan. The study aims to assess the efficacy of providing speech therapy awareness in private schools through a pre-post model.
- Conditions
- Speech and Language Disorder, Speech Therapy, Speech Delay, Swallowing Disorder
- Trial name
- NCT04505696
- Testing
- Speech-Language Pathology Presentation
- Where
- Pakistan
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Riphah International University
DLD
Effect of Phonotactic Probability and Orthography on Vocabulary Learning
The purpose of the study is to investigate how phonotactic probability) and orthography affect vocabulary by children with low oral language levels.
- Trial name
- VOCAB+ (NCT06935851)
- Testing
- VOCAB +
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Language Development Disorders, Down Syndrome
Strategies for Teaching Verbs
This study is designed to evaluate whether children with Down syndrome and children with typical development exhibit different levels of accuracy demonstrating novel verbs taught under three conditions: semantic cues (perform…
- Conditions
- Language Development Disorders, Down Syndrome, Child Language
- Trial name
- NCT03441685
- Testing
- Semantic cues (perform action), syntactic cues (sentence frame), or combined semantic and syntactic cues
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Developmental Language Disorder, Language Impairment
Emergent Bilinguals: Child Language Proficiency and Language of Treatment
Of the 12 million children in the USA growing up bilingual, about 1 million experience Developmental Language Disorder (DLD), a disorder in language learning and use.
- Trial name
- NCT06866223
- Testing
- Sentence recast
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Houston
Developmental Language Disorder, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT05325333
- Testing
- Retrieval-based word learning: Expanding retrieval practice schedule, Retrieval-based word learning: Standard retrieval practice schedule
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Purdue University
Developmental Dyslexia
Prediction and Intervention in Developmental Dyslexia
The long-term goal of this study is to improve prediction of poor reading outcome at preschool age by using a combination of behavioural and neuroimaging measures and to evaluate a specific computerized training program to…
- Trial name
- LEXI (NCT02217696)
- Testing
- Computerized reading training
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Developmental Language Disorder
Sentence Prediction in Developmental Language Disorder
Millions of children - 7-12% of the school-age population - have developmental language disorder (DLD), a disorder that affects language learning, comprehension, and use.
- Trial name
- NCT07510854
- Testing
- Thematic role, Sentence complexity
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Child Development, Child Development Disorder
The Indonesian Version of Ages and Stages Questionnaire III Accuracy Compared to Bayley Scales of Infant Development III
This study aimed to evaluate the concurrent validity information of the 24-, 30-, and 36-month Indonesian ASQ-3 with the Bayley Scales of Infant and Toddler Development 3rd Edition (BSID-III) in Indonesian children.
- Conditions
- Child Development, Child Development Disorder, Development Delay, Developmental Delay
- Trial name
- NCT05408351
- Where
- Indonesia
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Dyslexia, Developmental, Reading
Enhancing Letter-Speech Sound Learning and Reading Network Activation With Transcranial Electrical Stimulation
This study investigates the effects of transcranial electrical stimulation (tES) on the brain and its potential to enhance reading-related learning.
- Conditions
- Dyslexia, Developmental, Reading, Dyslexia, Learning
- Trial name
- LexiStim (NCT07546292)
- Testing
- Transcranial random noise stimulation
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Silvia Brem
Developmental Language Disorder
Neuroimaging Reveals Treatment-related Changes in DLD
Children with developmental language disorders (DLD, aka specific language impairment), a prevalent pediatric disorder, experience hallmark grammar deficits with life-long impacts on educational and occupational outcomes.
- Trial name
- NCT05268341
- Testing
- My Sentence Builder
- Where
- 6 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Ankyloglossia, Speech Delay
Frenuloplasty for Speech and Myofunctional Outcomes
Children with ankyloglossia (tongue tie) can have abnormal tongue function, putting them at a disadvantage when it comes to speech and articulation.
- Conditions
- Ankyloglossia, Speech Delay, Dentofacial Abnormalities
- Trial name
- NCT06089629
- Testing
- Lingual frenuloplasty
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Oregon Clinic