Clinical trials: Device
Knee Osteoarthritis (Knee OA)
Neuromuscular Control and Motor Unit Behavior in Patients With Knee Osteoarthritis
This study aims to examine the effects of moderate-intensity strength training, performed with or without an unloading knee orthosis (valgus-corrective or sham mode), on muscle function, motor unit behavior, and force modulation…
- Trial name
- NCT07544693
- Testing
- the strengthening program
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Mild Cognitive Impairment, Cognitive Impairment
SNIFF - 3-Week Aptar CPS Device
The SNIFF 3-Week Aptar Device study will involve using a device to administer insulin or placebo through each participant's nose or intra-nasally. Insulin is a hormone that is produced in the body.
- Conditions
- Mild Cognitive Impairment, Cognitive Impairment, Alzheimer Disease, Early Onset
- Trial name
- NCT05006599
- Testing
- Insulin (Humulin® R U-100), Aptar Pharma CPS Intranasal Delivery Device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Orthodontic Appliance Complication
Stability of Maxillary Anterior Teeth After Two Years of Retention in Adolescents Comparing Two Bonded and a Vacuum-formed Retainer
After orthodontic treatment 3 different retention devices will be compared.Thirty patients in each group; Group 1) Bonded retainer 13-23, Group 2)Bonded retainer 12-22 and Group 3) Vacuum-formed retainer covering all erupted…
- Trial name
- NCT04616755
- Testing
- Measuring changes of Little´s irregularity index ( sum of 5 contact point discrepancies together) measured in mm 2 years after retention have been I place.
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kronoberg County Council
Contraception
Intra Uterine Device Insertion in Nulliparous Women
Over the last several years, more and more women are choosing intrauterine contraception (IUDs) to meet their birth control needs.
- Trial name
- NCT01422226
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Arrhythmia
Clinical Performance Evaluation of the Hativ P30
Hativ P30 is intended to record, store, and transfer one-and two-channel ECG rhythms, and analyze them based on an artificial intelligence (AI) algorithm. In single channel mode, Hativ P30 can record lead-I.
- Trial name
- NCT06713226
- Testing
- Hativ P30 and 12-lead ECG comparator device
- Volunteers
- healthy volunteers welcome
- Sponsor
- VUNO Inc.
Chronic Heart Failure With Reduced Ejection Fraction
randOmized stUdy Using acceleromeTry to Compare Sacubitril/valsarTan and Enalapril in Patients With Heart Failure
The purpose of this randomized, actively controlled, double-blind study with prospective data collection was to assess differences between sacubitril/valsartan versus enalapril in increasing exercise capacity and non-sedentary…
- Trial name
- OUTSTEP-HF (NCT02900378)
- Testing
- LCZ696 (Sacubitril/Valsartan), Enalapril
- Where
- 119 sites in Belgium, Bulgaria and 17 more
- Volunteers
- 621 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Corneal Thickness Measurement, Epithelial Thickness Measurement
Repeatability, Reproducibility and Comparison of Cirrus OCT, RTVue OCT, MS-39 OCT, and Insight 100 VHFDU
The purpose of this study is to evaluate the repeatability and reproducibility of corneal, epithelial, and LASIK flap thickness using the Carl Zeiss Meditec Cirrus HD OCT 5000, Optovue RTVue OCT, CSO MS-39 OCT, and ArcScan…
- Conditions
- Corneal Thickness Measurement, Epithelial Thickness Measurement, LASIK Flap Thickness Measurement, SMILE Cap Thickness Measurement
- Trial name
- NCT03473847
- Testing
- ArcScan Insight 100 very high-frequency digital ultrasound, Carl Zeiss Meditec Cirrus HD OCT 5000, Optovue RTVue OCT
- Where
- United Kingdom
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- London Vision Clinic
Pain Perception of the New Device, The Pain Related Behavior
Computer Controlled Local Anesthesia in Children
Introduction: Effective pain control is critical in pediatric dentistry. The effectiveness of pain control in children can be influenced by child characteristics .
- Conditions
- Pain Perception of the New Device, The Pain Related Behavior, The Effectiveness of Anesthesia
- Trial name
- STA machine (NCT02025140)
- Testing
- Computer controlled anesthesia, conventional anesthesia syringe
- Where
- Saudi Arabia
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Obstructive Sleep Apnea, Sleep Position Trainer
RCT: Oral Appliance Therapy and Sleep Position Trainer in Patients With Position Dependant Obstructive Sleep Apnea
SUMMARY Rationale: Fifty-six percent of patients with Obstructive Sleep Apnea (OSA) are position dependent, defined as having an AHI, which is at least twice as high in supine sleeping position compared to the AHI during sleep in…
- Conditions
- Obstructive Sleep Apnea, Sleep Position Trainer, Oral Appliance Therapy
- Trial name
- POSA (NCT02045576)
- Testing
- sleep position trainer, Oral Appliance Therapy
- Where
- 2 sites in Netherlands
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Hypertension, Blood Pressure
Performance of the Aktiia Optical Blood Pressure Monitoring Device Against Double Auscultation
This study with N = 225 participants (1 cohort of a minimum of 85 and maximum of 140 participants, and an additional cohort with 85 participants) over 9 visits has been designed to assess the accuracy of Aktiia.product-us…
- Conditions
- Hypertension, Blood Pressure, Heart Rate
- Trial name
- NCT05236348
- Testing
- Aktiia.product-us
- Where
- Switzerland
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Aktiia SA
Urinary Tract Infections, Proteinuria
Scanadu Urine Device Validation Study Protocol
This study will test Scanadu Urine Device for clinical performance and usability.
- Conditions
- Urinary Tract Infections, Proteinuria, Ketone Urine, Hematuria
- Trial name
- NCT02973178
- Testing
- Scanadu Urine Device
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Scanadu, Inc.
Pressure Ulcer, Pressure Injury
What is the Incidence of Pressure Ulcer Category II-IV (Including Deep-tissue Injury and Unstageable) on a Static Air Foam Hybrid Mattress?
Pressure ulcers are a serious and common problem for residents admitted to long-term care facilities and community care patients.
- Conditions
- Pressure Ulcer, Pressure Injury, Pressure Sore, Bed Sore
- Trial name
- NCT05142878
- Testing
- Ultracore Repose® mattress
- Where
- 5 sites in Belgium
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University Ghent
Obesity, Metabolic Diseases
Fibrosis a New Pathological Actor in Adipose Tissue
Adipose tissue (AT) has specific alterations in obesity in particular increased fibrosis amount compared to lean subjects. Fibrosis amount measured by immunohistochemistry on adipose biopsies appears to to predict weight loss…
- Conditions
- Obesity, Metabolic Diseases, Fibrosis, Body Weight
- Trial name
- fibrota (NCT01655017)
- Testing
- biopsy
- Where
- 2 sites in France
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy
Brain Computer Interface Control of a Robotic Device
Noninvasive Brain-Computer Interfaces (BCIs) have been used to control a number of virtual and physical objects through the voluntary modulation of brain rhythms.
- Trial name
- NCT02069938
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Abdominal Fat
A Pilot Study Testing a Noninvasive Cryolipolysis Device Versus a High Intensity Focused Ultrasound Device for Fat Reduction
The purpose of this study is to compare the safety and effectiveness of the Zeltiq System and LipoSonix System for fat reduction and improving body shape.
- Trial name
- NCT01976247
- Testing
- High Intensity Focused Ultrasound Device, Noninvasive Cryolipolysis Device
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pulpotomy, Dental Caries
Pain and Anxiety Reducing During Dental Treatment in Children Using Video Game on Tablet Device With Joystick.
The aim of this study is to evaluate the effectiveness of two different distraction techniques (Audio Video Distraction /Video Game Distraction) in the management of anxious pediatric patients during dental treatment.
- Conditions
- Pulpotomy, Dental Caries, Primary Teeth
- Trial name
- NCT05191836
- Testing
- Evaluation of the effectiveness of Video Game Distraction in the management of anxious pediatric patients during dental treatment, Evaluation of the effectiveness of Audio Video Distraction in the management of anxious pediatric patients during dental treatment, Evaluation of the anxiety in pediatric patients during dental treatment without using any type of distraction aids
- Where
- Syria
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Damascus University
Basic Cardiac Life Support
Assessment of Chest Compression Depth Obtained Using the Smartphone Application as an Educational Tool With New Attachment Device
To improve the quality of CPR education, we want to assess the validity and reliability of the feedback depth measured by smartphone applications according to the smartphone attachment sites as an educational tool.
- Trial name
- NCT02964832
- Testing
- Grasp method, Armband-in-hand method, Armband-on-arm method
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Male Circumcision, HIV Prevention
Follow Up Study to Evaluate a Non-Surgical Device for Adult Male Circumcision for Screen Failure Subjects
It is well known from a range of observational and epidemiological studies that the lifetime risk of acquiring HIV among males can be significantly reduced via circumcision by 53%-60% and by up to 73% in post-trial observation.
- Conditions
- Male Circumcision, HIV Prevention, Screen Failure Subjects, Narrow Foreskin
- Trial name
- RMC-05 (NCT02281435)
- Testing
- PrePex™ device
- Where
- Rwanda
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda
Left Atrial Appendage Closure, Thrombosis
Short-Term Anticoagulation Versus Antiplatelet Therapy for Preventing Device Thrombosis Following Left Atrial Appendage Closure
The objective of the study is to compare short-term (8 weeks) anticoagulation therapy (DOAC) vs. antiplatelet therapy for the prevention of device thrombosis following transcatheter LAAC.
- Conditions
- Left Atrial Appendage Closure, Thrombosis, Stroke, TIA
- Trial name
- ANDES (NCT03568890)
- Testing
- Rivaroxaban, dabigatran, apixaban, or edoxaban, Clopidogrel -75 mg/day, Low dose aspirin -80 to 125 mg/day-
- Where
- Canada
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Hemorrhagic Stroke, Ischemic Stroke
Early Feasibility Study of the SENSE Device
A single site, study of the SENSE device in up to 20 study subjects, (five healthy controls and five each with ICH, AIS with LVO and AIS without LVO) in whom SENSE can be applied within 24 hours of stroke symptom onset.
- Trial name
- NCT03827720
- Testing
- SENSE Device
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sense Diagnostics, LLC