Clinical trials: Dextrose Concentration
Diabetes Mellitus, Type II
A Study to Compare the Concentrations of LY2189265 After Different Methods of Administration to Healthy Volunteers.
LY2189265 is an investigational drug being developed for the treatment of type 2 diabetes mellitus. This study will compare the concentrations of LY2189265 using different methods of administration: subcutaneous (or SC- an…
- Trial name
- NCT01301092
- Testing
- LY2189265
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Healthy Volunteers, Pharmacokinetics of ASP1941
Study of the Pharmacokinetics of ASP1941 and the Effect on Glucose Concentrations in Male and Female Young and Elderly Healthy Adults
This is a study of the pharmacokinetic profile and safety and tolerability of ASP1941after repeat dosing and the effect of ASP1941 on glucose levels in non elderly and elderly healthy adult male and female subjects.
- Trial name
- NCT01678287
- Testing
- ASP1941
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.
Diabetes Mellitus, Type 2, Healthy Participants
A Research Trial Looking at the Comparability of 2 Different Concentrations of Semaglutide for the 0.5 Milligram (mg) Dose
In this study, a known investigational medicine called 'semaglutide' will be tested in 2 drug concentrations of 0.68 milligram per milliliter (mg/mL) and 1.34 mg/mL.
- Trial name
- NCT05689099
- Testing
- Semaglutide B, 1.34 mg/mL, Semaglutide B, 0.68 mg/mL
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Blood Glucose Concentration, Blood Glucose Self Monitoring
Effect of Low Water Intake on Glucose Regulation Measured Using Continuous Glucose Monitoring
This clinical trial aims to learn if increasing water intake for five days can lower blood glucose in healthy, free-living individuals.
- Trial name
- NCT06645431
- Testing
- Water Intake
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Feeding Behaviors, Lack of Satiety
Metabolic and Neurofunctional Responses to Breakfasts
This study aims at assessing the effects of glucose and different types of breakfast on metabolic and neurofunctional responses in healthy individuals.
- Conditions
- Feeding Behaviors, Lack of Satiety, Attention Deficit and Disruptive Behavior Disorders
- Trial name
- NCT02897570
- Testing
- Glucose, Milk & Cereals, Milk, apple & snack
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ospedale San Donato
Insulin Sensitivity
The Effect of TLR4 Inhibition in Obese and Type 2 Diabetic Subjects
To determine whether pharmacologic inhibition of Toll-like receptor 4 (TLR4) with eritoran for injection (E5564) will reduce inflammation and improve glucose metabolism in insulin resistant (obese and T2DM) subjects.
- Trial name
- Eritoran2 (NCT02267317)
- Testing
- Eritoran, D5W
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Metabolic Syndrome X, Insulin Resistance Syndrome X
Magnesium and Metabolic Syndrome: A Dose-response Meta-analysis
Magnesium is an essential mineral found in many foods; rich sources include whole grains, green leafy vegetables, coffee, and legumes.
- Conditions
- Metabolic Syndrome X, Insulin Resistance Syndrome X, Metabolic Cardiovascular Syndrome, Dysmetabolic Syndrome X
- Trial name
- NCT02151227
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Cardiovascular Risk Factor, Cardiovascular Diseases
Substituting Sitting With Standing and Walking in Free-living Conditions Improves Daily Glucose Profile in South Asians
The purpose of this study is to investigate the effects of substituting sitting under free-living conditions in South Asian adults with overweight and obesity on continuous glucose profiles.
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Diabetes, Type 2 Diabetes
- Trial name
- NCT04645875
- Testing
- SIT regimen, SITless regimen
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Bedfordshire
Diabetes Mellitus, Type 2
To Observe the Clinical Effect of Femoral Nerve Block With Low Concentration of Ropivacaine Based on DPN Grading
The purpose of this study was to quantitatively standardize the performance of patients with DPN with different course of disease using high-frequency ultrasound, and to design experiments to verify the conclusion that DPN…
- Trial name
- NCT06732362
- Testing
- Different DPN ratings
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zheng Guo
PreDiabetes, Aging
Safety and Efficacy of KH-1 for Stimulating Autophagy in Non-diabetic Adults With Elevated Blood Glucose Concentration
Aging significantly impacts overall health and is a risk factor for developing diabetes. An estimated 50% of U.S. adults aged ≥65 years were reported to have prediabetes (defined as having a fasting glucose concentration of…
- Trial name
- NCT06445569
- Testing
- KH-1
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kalin Health, LLC
Type 1 Diabetes, Type 2 Diabetes
Comparison of Noninvasive Blood Glucose Concentrations Relative to Finger Capillary Blood Glucose References
The purpose of the study is to prospectively evaluate a noninvasive, near-infrared based method for measuring glucose concentration relative to invasive blood reference measurements.
- Conditions
- Type 1 Diabetes, Type 2 Diabetes, Gestational Diabetes
- Trial name
- NCT01415544
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- InLight Solutions
Healthy
Study of Acute Effects of Sn-1 and Sn-3 Palmitic Acid-rich or Stearic Acid-rich Fats on Metabolic Markers
To determine the effect of degree of fat saturation on postprandial lipemia, haemostatic and inflammatory markers, gut hormone concentrations, satiety perceptions, and insulinemic responses in healthy adult subjects.
- Trial name
- NCT01428960
- Testing
- Palm Mid Fraction, Shea Butter, High Oleic Sunflower Oil
- Where
- Malaysia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Mental Health, Cognition
Short-term Effect of Glucose and Sacharose Ingestion on Cognitive Performance and Mood in Elderly
The objective of the current study is to determine the acute effect of a glucose drink and a sacharose drink compared to a placebo on cognitive performance in elderly with light memory complaints.
- Conditions
- Mental Health, Cognition, Memory, Attention
- Trial name
- NCT01427231
- Testing
- glucose, sacharose
- Where
- Netherlands
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Gestational Diabetes
Associations of Plasma Vanadium Concentrations With Gestational Diabetes Mellitus
Background: Vanadium compounds have been shown to exert insulin-mimetic effects and thereby control glucose homeostasis. However, studies regarding the levels of vanadium and gestational diabetes mellitus (GDM) are limited and…
- Trial name
- NCT05267457
- Testing
- Plasma vanadium concentration
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Liegang Liu
Insulin Resistance, Obesity
Vitamin D and Glucose Metabolism in Pediatrics
The discovery that the vitamin D receptor is expressed in more than 30 tissues indicates that the physiologic functions of vitamin D are much broader than its well-known role in the regulation of calcium absorption and bone…
- Conditions
- Insulin Resistance, Obesity, Vitamin D25 Insufficiency
- Trial name
- NCT01386736
- Testing
- Vitamin D drops
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Blood Glucose Concentration, Type 2 Diabetes
Effect of Pasta on Blood Glucose Response in Normal Subjects
The objective of this study is to determine whether ingestion of modified pasta products (Dreamfields, Miracle Noodles) result in an improvement in blood glucose concentration when compared with a traditional pasta.
- Conditions
- Blood Glucose Concentration, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- NCT01469312
- Testing
- modified pasta
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Healthy Adults
Effect of Palm Sugar on Blood Glucose Concentrations
The purpose of this study is to determine by how much, the ingestion of palm sugar increases blood glucose concentrations and what the corresponding glycaemic index is.
- Trial name
- LIPS (NCT01240837)
- Testing
- Arenga Pinnata Sugar, Glucose, Sucrose
- Where
- Netherlands
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Reproductive Age, PCOS (Polycystic Ovary Syndrome)
Functional Proteins in Polycystic Ovary Syndrome
The concentration of functional proteins: kisspeptin, ghrelin, zonulin will be measured and compared in women with polycystic ovary syndrome (PCOS) and insulin resistance (IR), in women with PCOS without IR, and in women without…
- Trial name
- NCT06793098
- Testing
- Measurement of kisspeptin concentration, Measurement of ghrelin concentration, Measurement of zonulin concentration
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Reproductive Age, PCOS (Polycystic Ovary Syndrome)
Pro- and Anti-inflammatory Cytokines in PCOS
The study will involve measurements and comparisons of the concentrations of pro-inflammatory cytokines: IL-6, TNF-α, IL-18, as well as anti-inflammatory cytokine IL-4 in women with polycystic ovary syndrome (PCOS) and insulin…
- Trial name
- NCT06793085
- Testing
- Measurement of interleukin-6 (il-6) concentration in blood serum, Measurement of fasting tumor necrosis factor α (TNF-α) concentration, Measurement of interleukin-18 (il-18) concentration
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Body Weight, Oxidative Stress
The Effect of a Meatless,Keto Restrictive Diet on Body Composition,Strength Capacity,Oxidative Stress,Immune Response
The subject of doctoral dissertation: Assessment of the effects of a meatless, ketogenic restrictive diet on body composition, strength capacity, oxidative stress and immune response During planning of research and topic of the…
- Conditions
- Body Weight, Oxidative Stress, Trimethylamine N-oxide, Immunologic Factors
- Trial name
- NCT05558488
- Testing
- Meatless, restrictive ketogenic diet
- Where
- Poland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Katarzyna Siedzik