Clinical trials: Diabetes, Type II
Diabetes Mellitus, Type 2
The Role of Gut Hormones and Hepcidin in Type 2 Diabetes Mellitus
This study aims to investigate the potential of the gut hormones GLP-1, PP, PYY and the iron regulatory hormone hepcidin as biomarkers for progression to complications in diabetes mellitus.
- Trial name
- NCT02413762
- Testing
- No intervention
- Where
- United Arab Emirates
- Volunteers
- 1,512 people, healthy volunteers welcome
- Sponsor
- Imperial College London Diabetes Centre
Prediabetic State, Diabetes Mellitus, Type 2
Noninvasive Skin Spectroscopy for Diabetes Screening
The objective of this study is to assess the performance of a noninvasive device for the early screening of Diabetes Mellitus.
- Trial name
- NCT00358254
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- InLight Solutions
Type 2 Diabetes and Exercise
Influence of Moderate Exercise on Blood Glucose in Type 2 Diabetics and Healthy Controls
Project description Research project title: Influence of moderate exercise on blood glucose in type 2 diabetics and healthy controls.
- Trial name
- DIEGO (NCT01765894)
- Testing
- 45 minutes of moderate exercise at the fasted state. Before test day 2: 3 days of carbohydrate loading.
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Type 2 Diabetes Mellitus
Study on Drug Interaction of HRS-1780 Tablets, Henagliflozin Tablets, Metformin Tablets and HRS-7535 Tablets in Healthy Human
This study was designed as a single-center, single-arm, open, fixed-sequence, self-controlled trial in healthy subjects.
- Trial name
- NCT06495931
- Testing
- HRS-1780 tablets, HR20033 tablets, HRS-7535 tablets
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.
Gestational Diabetes Mellitus
Prevention of Diabetes Mellitus Type 2 in Women Post Gestational Diabetes Mellitus Diagnosis
Diabetes Mellitus (DM) is a chronic metabolic disorder with increasing incidence and long term complications. Its incidence differs in various ethnic populations.Gestational DM (GDM) is diagnosed when impaired glucose tolerance…
- Trial name
- GDM (NCT01480895)
- Testing
- Lifestyle instruction for Jews and Bedouin GDM women.
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Diabetes
The Different Response of Endocrine Hormones to Hypoglycemia in Patients With Type 1 or Type 2 Diabetes
Endocrine hormones, not only blood glucose responsive hormones, but also sexual hormones, thyroid hormones, growth hormones and so on, may have response and activites in hypoglycemia.
- Trial name
- NCT05290207
- Testing
- The hyperinsulinaemic hypoglycaemic clamp
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Cardiovascular Diseases, Diabetes Mellitus, Type 2
Healthy Lifestyle Promotion Program in Communities From the Yaqui Valley
The aim is to evaluate the change in indicators of lifestyle and its effect on cardiometabolic biomarkers as a response to an integrative mother-child intervention to promote healthy lifestyles and prevent food insecurity and…
- Trial name
- NUTRIGANDO (NCT05945862)
- Testing
- NUTRIGANDO
- Where
- Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Instituto Tecnologico de Sonora
Prediabetic State & High Risk Individuals on the Basis of Diabetes Risk Score
(Pakistan Diabetes Prevention Program PDPP)
The Karachi-based Pakistan Diabetes Prevention Study aims to address key issues in the prevention of type 2 diabetes. Approximately 20,000 people From four communities will be screened for diabetes risk factors using a…
- Trial name
- PDPP (NCT01530165)
- Testing
- Life style intervention
- Where
- Pakistan
- Volunteers
- 1,564 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Type 2 Diabetes Mellitus
Safety/Efficacy of Sitagliptin in Patient w/ Type 2 Diabetes (0431-801)
The purpose of this study is to test the safety and effectiveness of sitagliptin in patients with type 2 diabetes.
- Trial name
- NCT00541775
- Testing
- Sitagliptin, Comparator: Rosiglitazone, Comparator: Metformin
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Type II, Overweight and Obesity
Microclinic Social Induction Pilot Intervention for Diabetes and Obesity Management in Qatar
The purpose of the study is to pilot-phase test the effectiveness of the microclinic social induction model and its effects on behavioral and metabolic outcomes in different levels of social and familial relationships in Qatar.
- Conditions
- Diabetes Mellitus, Type II, Overweight and Obesity, Hypertension, Behavioral Lifestyle Change
- Trial name
- NCT02175537
- Testing
- Microclinic Social Induction Diabetes and Obesity Program
- Where
- Qatar
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Microclinic International
Type 2 Diabetes
Prevention of Type 2 Diabetes Amongst South Asians With Central Obesity and Prediabetes
The investigators' general goal is to identify approaches to risk stratification and health promotion through lifestyle modification that are acceptable, effective and efficient for prevention of T2D in South Asian communities…
- Trial name
- iHealth-T2D (NCT02949739)
- Testing
- Intensive lifestyle modification
- Where
- United Kingdom
- Volunteers
- 5,244 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Diabetes Mellitus
Measurement Algorithm Control and Optimization With Subsequent Performance Evaluation of Sanmina Non-invasive Biosensors During a Standardized Meal Test in Patients With Diabetes Mellitus Type 1 and Type 2
Measurement algorithm control and optimization with subsequent performance evaluation of Sanmina biosensors in monitoring of glucose, heart rate (HR), and SpO2 in patients with type 1 and type 2 diabetes during a standardized…
- Trial name
- NCT04379427
- Testing
- Sanmina Biosensor
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sciema UG
Diabetes Mellitus, Type 2
Comparative Effects of Periodized Circuit Training and Conventional Strength Training in Patients With Diabetes Type II
Patients with type II diabetes are at high risk of developing cardiovascular diseases due to increased blood sugar, inflammation, insulin resistance, and physical inactivity.
- Trial name
- NCT07484672
- Testing
- Group A: Periodized Circuit Training, Group B: Strength and Endurance Exercise Training Protocol
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Blood Glucose, Blood Insulin
Impact of Fluid Milk on Post-meal Glycemia and Insulinemia in Overwt/Obese Adults
Blood sugar and insulin levels after a meal may be altered by the food and beverages a person consumes. Keeping a healthy blood sugar level may help prevent and manage type 2 diabetes and related diseases.
- Trial name
- S37 (NCT01951287)
- Testing
- Acute beverage (water) consumption, Acute beverage (Black Coffee) consumption, Acute beverage (Orange Juice) consumption
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Purdue University
Type 2 Diabetes
A Study to Evaluate the Pharmacokinetics and Safety Between Single Oral Administration of BR3006 and Co-administration of BR3006A, BR3006B and BR3006C in Healthy Adult Volunteers Under Fed Conditions
The purpose of this clinical study is to evaluate the pharmacokinetics and safety between single oral administration of BR3006 and co-administration of BR3006A, BR3006B and BR3006C in healthy adult volunteers under fed conditions
- Trial name
- NCT06890299
- Testing
- BR3006, BR3006A, BR3006B
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Prospective Study on Diabetes Mellitus and Its Complications in Newly Diagnosed Adult Patients
The aim of the prospective observational GDC-Study in patients with newly diagnosed diabetes mellitus aged 18-69 years at inclusion into the study is to characterize in detail the clinical, metabolical and immunological phenotype…
- Trial name
- GDC (NCT01055093)
- Where
- Germany
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
Type 2 Diabetes Mellitus, Cardiovascular Diseases
Network-based Approach in Type 2 Diabetes and Its Cardiovascular Risk
PIRAMIDE study design will test the hypothesis that simultaneous interactions between DNA methylation and microRNAs may hit T2D candidate genes and predict the development of T2D-related cardiovascular complications.
- Trial name
- PIRAMIDE (NCT03792607)
- Where
- Italy
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Giuditta Benincasa
Diabetes Mellitus, Type 2, Hypertension
Scaling Up NCD Interventions in South East Asia
The SUNI-SEA study is an intervention study that measures effectiveness and cost-effectiveness of prevention and early diagnosis of diabetes and cardiovascular diseases in communities and primary healthcare (PHC) facilities in…
- Conditions
- Diabetes Mellitus, Type 2, Hypertension, Cardiovascular Diseases
- Trial name
- SUNI-SEA (NCT05239572)
- Testing
- screening, prevention and counselling
- Where
- Vietnam
- Volunteers
- 16,850 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Irreversible Pulpitis, Diabetes Mellitus, Type 2
Outcome of Complete Pulpotomy in Healthy and Type 2 Diabetic Patients in Permanent Teeth With Irreversible Pulpitis
Endodontic research on the effects of DM on pulp tissues is scarce. Diabetic human and animal histological research demonstrated a decreased reparatory response in the pulp, resulting in chronic pulp inflammation and reduced…
- Conditions
- Irreversible Pulpitis, Diabetes Mellitus, Type 2, Healthy
- Trial name
- NCT06586775
- Testing
- Pulpotomy
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Obesity, Type 2 Diabetes
Effects of Advanced Glycation Endproducts on Satiety and Inflammation
The purpose of the meal study is to investigate acute effects on satiety and inflammation of advanced glycation endproducts (AGE) in healthy overweight subjects.
- Conditions
- Obesity, Type 2 Diabetes, Insulin Resistance, Cardiovascular Disease
- Trial name
- AGE-1 (NCT01434407)
- Testing
- Dietary meal intervention
- Where
- Denmark
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
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