Clinical trials: Diabetes During Pregnancy
IUGR, Gestational Diabetes
PED NEONAT 20-000599 Fetal Body Composition
Obesity is an ongoing public health problem that is difficult to treat. There is evidence that obesity has fetal origins. Body composition, including visceral, subcutaneous, brown, and hepatic fat have been found to be important…
- Conditions
- IUGR, Gestational Diabetes, Pregnancy Related
- Trial name
- NCT04508751
- Testing
- 3T "Free-Breathing" Fetal Magnetic Resonance Imaging
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gestational Diabetes, Maternal Complication of Pregnancy
CAPO: Continuous Glucose Monitoring in A2 Gestational Diabetes and Pregnancy Outcomes
This study will utilize continuous glucose monitoring in women with A2 gestational diabetes. Women will be randomized to continuous glucose monitoring or routine care with fingersticks to check their blood glucose four times…
- Trial name
- CAPO (NCT04219085)
- Testing
- Continuous Glucose Monitor, Routine Care
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Yale University
Disorder of Glucose Regulation
Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM
Gestational diabetes mellitus (GDM) is defined as "any degree of glucose intolerance with onset or first recognition during pregnancy." GDM is one of the most frequent metabolic disorders occurring during pregnancy.
- Trial name
- NCT01856907
- Testing
- Sitagliptin-Metformin, Metformin
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Woman's
Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy
Clinic to Community Connections - Broader Distribution
This study addresses education needs in gestational diabetes care and followup at the staff and patient levels. In the initial phase, nurses and community health workers will complete specific training modules on gestational…
- Trial name
- NCT04474795
- Testing
- Staff -Educational training
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Gestational Diabetes
Meals 4 Moms: A Multilevel Community-based Lifestyle Intervention for GDM
The goal of the project is to conduct a pilot feasibility randomized trial comparing a community-based lifestyle intervention called Meals for Moms (M4M) versus the usual care for pregnant persons diagnosed with gestational…
- Trial name
- NCT06227247
- Testing
- Meals4Moms Intervention
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- UConn Health
Gestational Diabetes Mellitus
Barriers to Adherence to Recommended Follow-up in Women With a History of Gestational Diabetes
The purpose of this study is to find out whether women who have had gestational diabetes mellitus (GDM) will make healthier lifestyle choices, achieve weight goals, and complete postpartum care assessments after receiving two…
- Trial name
- NCT01681147
- Testing
- 2 online nutrition and exercise education classes, Self monitoring of blood glucose levels
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Joslin Diabetes Center
Hypertension, Hypertension in Pregnancy
Bridging the Gap From Postpartum to Primary Care
Chronic health conditions affect most older adults. Preventative medicine and risk management strategies, especially when applied earlier in life, are essential to altering the trajectory of a disease and ultimately improving…
- Conditions
- Hypertension, Hypertension in Pregnancy, Diabetes Mellitus, Gestational Diabetes
- Trial name
- NCT05543265
- Testing
- Default appointment scheduling, Targeted messaging, Nudge Reminders
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Massachusetts General Hospital
Mild Gestational Diabetes
Treatment of Mild Gestational Diabetes With Glyburide Versus Placebo
This is a randomized prospective trial which addresses the question of whether use of an oral hypoglycemic agent as an adjunct to diet therapy in women with mild gestational diabetes will result in achieving euglycemia in a…
- Trial name
- NCT00744965
- Testing
- Glyburide
- Where
- United States
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Gestational Diabetes
A Study on the Use of Real -Time Continuous Glucose Monitoring (RT-CGM) in Gestational Diabetes
The purpose of this study is to examine whether RT-CGM (real time continuous glucose monitoring) use improves glucose control, maternal outcomes, and fetal outcomes in patients diagnosed with gestational diabetes.
- Trial name
- NCT04803357
- Testing
- Continuous glucose monitor
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Washington
Proteinuric Kidney Disease, Diabetic Nephropathy
Aldosterone Breakthrough During Diovan, Tekturna, and Combination Therapy in Patients With Proteinuric Kidney Disease
Primary Hypothesis: Aldosterone breakthrough will occur at a far lower frequency during renin inhibition (0-10% over 9 months), alone or in combination with an ARB, compared to conventional ARB therapy (35-45% over 9 months).
- Conditions
- Proteinuric Kidney Disease, Diabetic Nephropathy, Hypertensive Nephrosclerosis, IgA Nephropathy
- Trial name
- NCT01129557
- Testing
- Aliskiren, Valsartan
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Columbia University
Gestational Diabetes, Eye Diseases
Fundus Findings and Thiol-Disulfide Homeostais
Gestational diabetes mellitus is associated with abnormal blood sugar levels throughout pregnancy in women without prior diabetes. Many studies have been conducted on the relationship between diabetes and oxidative stress.
- Conditions
- Gestational Diabetes, Eye Diseases, Retinal Disease, Oxidative Stress
- Trial name
- NCT05958927
- Testing
- tear test and eye measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suzan Dogruya
Chronic Renal Impairment, Diabetes Mellitus
Renal Safety of Iopamidol Versus Iodixanol During Coronary Angiography in Diabetic Patients
The purpose of this study is to compare the incidence of contrast-induced nephropathy (CIN) following the administration of iopamidol-370 (Iopamiro-370) and iodixanol-320 (Visipaque 320) in patients with moderate-to-severe…
- Trial name
- RECARE (NCT00782639)
- Testing
- Iopamidol injection 76%, iodixanol
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Bracco Diagnostics, Inc
Diabetes in Pregnancy
Incentives and Glucose Adherence in Diabetes
Diabetes in pregnancy carries significant pregnancy specific risks and requires frequent glucose monitoring to reduce these risks.
- Trial name
- NCT03338829
- Testing
- Positive incentive, Loss aversion
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Blood Loss, Surgical
Vasopressin Administration During Laparoscopic Myomectomy: a Randomized Controlled Trial
The main purpose of this study is to compare blood loss at the time of laparoscopic or robotically-assisted laparoscopic myomectomy when using different amounts of dilute vasopressin solution.
- Trial name
- NCT01393704
- Testing
- Vasopressin
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Brigham and Women's Hospital
Diabetes Mellitus in Pregnancy
SweetMama: Testing of a Novel Technology for Diabetes Education and Support to Pregnant Women
Diabetes during pregnancy is a challenging clinical situation requiring substantial patient engagement. The investigators have developed a novel early-phase tool, called SweetMama, that incorporates educational, motivational and…
- Trial name
- NCT03240874
- Testing
- SweetMama Focus Groups, SweetMama Individual Testing, SweetMama Feasibility Testing - Pilot Randomized Trial
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Self-Efficacy for Decision Making, Apgar Score
Effectiveness of a Pender's Health Promotion Model-Based Diabetes Self-Management Program in Gestational Diabetes: A Clinical Trial
The aim was to evaluate the effect of a nursing education intervention based on Pender's SGM on gestational diabetes management and healthy lifestyle behaviors for pregnant women diagnosed with gestational diabetes.
- Conditions
- Self-Efficacy for Decision Making, Apgar Score, Behavior Change, Maternal and Neonatal Outcomes
- Trial name
- NCT07060963
- Testing
- Motivational interviews within the context of a health promotion-based diabetes self-management program
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people
- Sponsor
- Ankara Yildirim Beyazıt University
Gestational Diabetes Mellitus in Pregnancy
Adding Metformin to Insulin in Controlling Pregestational and Gestational Diabetes Mellitus
The purpose of the study to prove benefits of adding metformin to insulin for controlling presentational and gestational diabetes mellitus and improving neonatal outcome.
- Trial name
- NCT03106870
- Testing
- Insulin Mixtard, Metformin
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Diabetes, Gestational
Gestational Diabetes Mellitus Trial (GDM)
Gestational diabetes mellitus (GDM) is a type of diabetes (high blood sugar) that occurs in pregnant women. This study will determine whether treating pregnant women who have mild GDM improves the health of their babies.
- Trial name
- GDM (NCT00069576)
- Testing
- nutritional counseling, self blood glucose monitoring
- Where
- 16 sites in United States
- Volunteers
- 7,381 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Non Insulin Dependent Diabetes, Pregnancy
Effectiveness of Metformin Compared to Insulin in Pregnant Women With Mild Preexisting or Early Gestational Diabetes
Many women come into pregnancy with diabetes that is controlled with either Metformin or diet control; however, the current standard of care for the treatment of preexisting diabetes in pregnancy is insulin.
- Trial name
- MIPOD (NCT00835861)
- Testing
- Metformin, Insulin
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of North Carolina, Chapel Hill
Gestational Diabetes Mellitus
Humalog® Mix50/50(tm) as a Treatment for Gestational Diabetes
Evaluation of the Safety and Efficacy of Humalog® Mix50/50TM administered as 3 injections daily to Humalog® plus Humulin N® insulin administered as 6 separate injections daily in terms of glucose control for women with…
- Trial name
- NCT01613807
- Testing
- Insulin LISPRO, Insulin, Long-Acting and Insulin
- Volunteers
- 40 people
- Sponsor
- Sansum Diabetes Research Institute