Clinical trials: Diabetes During Pregnancy
Type II Diabetes Mellitus, Gestational Diabetes Mellitus
Intrapartum Glycemic Control With Insulin Infusion Versus Rotating Fluids
This study will determine whether rotating intravenous (IV) fluid is better than receiving insulin to control a baby's blood sugar after delivery in laboring women with diabetes.
- Trial name
- NCT03912363
- Testing
- Rotating fluids protocol, Insulin infusion protocol
- Where
- 2 sites in United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Diabetes, Gestational
Metformin Postpartum for GDM RCT for Reduced Weight Retention
The purpose of this study is to determine whether the study drug metformin is helpful in reducing weight after pregnancy in women with gestational diabetes.
- Trial name
- NCT01280409
- Testing
- Metformin
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- The University of Texas Health Science Center, Houston
Gestational Diabetes, Type2 Diabetes
Mobilizing Doulas to Empower Black Women in Post-partum Diabetes Prevention
Black and White mothers have similar prevalence of gestational diabetes mellitus (GDM). However Black mothers are more likely to develop Type 2 Diabetes Mellitus (T2DM) after a diagnosis of GDM.
- Trial name
- NCT04406792
- Testing
- DPP only, Diabetes Prevention Program (DPP) online + doula divas
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Gestational Diabetes, Pregnancy Complications
Web/Smartphone-based Lifestyle Coaching Program in Pregnant Women With Gestational Diabetes
Gestational diabetes mellitus (GDM) affects one fifth of Singaporean pregnancies and can result in short and long term complications for mother and child.
- Conditions
- Gestational Diabetes, Pregnancy Complications, Weight Gain
- Trial name
- SMART-GDM (NCT03249896)
- Testing
- Habits-GDM mobile app
- Where
- Singapore
- Volunteers
- 340 people
- Sponsor
- National University Hospital, Singapore
Diabetes Mellitus, Gestational Diabetes Mellitus (GDM)
A Proof of Concept (PoC), Randomized, Controlled Study to Validate the Algorithm and Evaluate the Accuracy, Safety and Pain Level of the Smartest-AE in Comparison to Self-measure Blood Glucose Levels
The study is conducted in Israel so plain language for the study is exist in Hebrew only
- Conditions
- Diabetes Mellitus, Gestational Diabetes Mellitus (GDM), Pre Diabetes
- Trial name
- NCT06587087
- Testing
- Smartest-AE: The lancet that will be used will be the Vitrex Soft Lite lll 28G.
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Smartest Technologies
Pregnancy, Gestational Diabetes
Group Versus Traditional Prenatal Care for Diabetes
The investigators primary objective is to conduct a randomized trial to determine the effect of diabetes group prenatal care on glycemic control and postpartum weight retention in women with type 2 diabetes and gestational…
- Conditions
- Pregnancy, Gestational Diabetes, Type 2 Diabetes
- Trial name
- NCT03301792
- Testing
- Group prenatal care
- Where
- 2 sites in United States
- Volunteers
- 117 people
- Sponsor
- Washington University School of Medicine
Gestational Diabetes
Fetal Interventricular Septum Thickness and Maternal Gestational Diabetes Control
Glucose intolerance and gestational diabetes are common complications of pregnancy. Their prevalence varies worldwide secondary to differences in screening practices (one-step versus two-step approach) and population…
- Trial name
- NCT03654521
- Testing
- Fetal interventricular septum thickness
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Rambam Health Care Campus
Vitamin d Deficiency, Preeclampsia
25- Hydroxyvitamin D Levels in Pregnancy and Effects on Pregnancy Related Disorders
Evaluation of 25- Hydroxyvitamin D levels in pregnant women in Austria and potential related disorders Hypothesis: Austrian pregnant women are Vitamin D deficient Present vitamin D supplementation in pregnancy is insufficient…
- Conditions
- Vitamin d Deficiency, Preeclampsia, Preterm Delivery, Gestational Hypertension
- Trial name
- VIDIS (NCT04637880)
- Where
- Austria
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Gestational Diabetes
Intensive Management for Gestational Diabetes
This is a randomized clinical pilot trial designed to assess the feasibility of randomizing obese women with GDM to lower glycemic thresholds compared to standard care.
- Trial name
- GDM-MOMS (NCT02530866)
- Testing
- Lower glycemic targets
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Oklahoma
Obesity, Pregnancy
Inter-pregnAncy Coaching for a Healthy fuTure
The project focuses on prevention of major pregnancy and birth related complications : pregnancy-induced hypertension (PIH), gestational diabetes mellitus (GDM), caesarean section (CS), and large-for-gestational-age (LGA), i.e.
- Trial name
- inter-act (NCT02989142)
- Testing
- INTER-ACT
- Where
- 6 sites in Belgium
- Volunteers
- 1,100 people
- Sponsor
- KU Leuven
Gestational Diabetes
Gestational Diabetes - PrEvention of PostPartum Diabetes Study
Gestational diabetes is the most common metabolic abnormality during pregnancy. In a Swedish population 2-10% of all pregnant women are diagnosed with gestational diabetes mellitus (GDM).
- Trial name
- PEPP (NCT05112588)
- Testing
- Intervention
- Where
- Sweden
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Gestational Diabetes, Breast Feeding
Exclusive Breastfeeding Improves Puerperal Glucose Metabolism in Pregnant Women With Gestational Diabetes Mellitus and Links to Lipids Composition
Breastfeeding could effectively be associated with a lower risk of future type 2 diabetes (T2D) in women with gestational diabetes mellitus (GDM), but the short-term protective impact of puerperal breastfeeding on maternal…
- Conditions
- Gestational Diabetes, Breast Feeding, Lipid Metabolism Disorders
- Trial name
- NCT05629403
- Testing
- observe
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Nanjing Medical University
Non Insulin Dependent Diabetes, Pregnancy
Effectiveness of Metformin Compared to Insulin in Pregnant Women With Mild Preexisting or Early Gestational Diabetes
Many women come into pregnancy with diabetes that is controlled with either Metformin or diet control; however, the current standard of care for the treatment of preexisting diabetes in pregnancy is insulin.
- Trial name
- MIPOD (NCT00835861)
- Testing
- Metformin, Insulin
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of North Carolina, Chapel Hill
Gestational Diabetes Mellitus in Pregnancy
Adding Metformin to Insulin in Controlling Pregestational and Gestational Diabetes Mellitus
The purpose of the study to prove benefits of adding metformin to insulin for controlling presentational and gestational diabetes mellitus and improving neonatal outcome.
- Trial name
- NCT03106870
- Testing
- Insulin Mixtard, Metformin
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Alcohol Drinking
The Influence of Water and Salt Intake on Copeptin Levels During Moderate Alcohol Consumption
The main interest of this study is to investigate the influence of moderate alcohol consumption (beer) on salt-water homeostasis.
- Trial name
- NCT03883503
- Testing
- Beer 5%o, Beer 8.5%o and water, Beer 8.5%o and stock
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Pregnant With Complication, Preeclampsia
Developing & Evaluating Models for Early Predicting Obstetrical Diseases in Pregnant Women by Non-invasive Prenatal Test
This is Observational study, aiming to investigate the potentiality of cffDNA and cfRNA by a non-invasive test, in combination with clinical characteristics, to establish models for early screening and predicting high-risk…
- Conditions
- Pregnant With Complication, Preeclampsia, Preterm Birth, Gestational Diabetes
- Trial name
- NCT06385366
- Where
- Vietnam
- Volunteers
- 1,105 people
- Sponsor
- Gene Solutions
Diabetes Mellitus in Pregnancy, Diabetes, Gestational
Glycemic Targets for Pregnant Women With GDM and T2DM
The purpose of this randomized clinical trial is to determine whether glycemic targets that are lower than those currently recommended by the American Diabetes Association (ADA) and the American College of Obstetricians and…
- Conditions
- Diabetes Mellitus in Pregnancy, Diabetes, Gestational, Diabetes Mellitus, Type 2
- Trial name
- NCT04672031
- Testing
- Glycemic Targets
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Diabetes, Gestational, Gastric Bypass Status for Obesity Complicating Pregnancy, Childbirth, or the Puerperium
Gestational Diabetes After Gastric Bypass Surgery
The goal of this trial is to compare different means of glucose monitoring in women with gestational diabetes and a history of gastric bypass surgery.
- Conditions
- Diabetes, Gestational, Gastric Bypass Status for Obesity Complicating Pregnancy, Childbirth, or the Puerperium, Pregnancy in Diabetic, Blood Glucose Self Monitoring
- Trial name
- NCT06291766
- Testing
- FreeStyle Libre 2, continous glucose monitoring
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane
Gestational Diabetes Mellitus (GDM)
Glucophage Plus Myo-Inositol vs Glucophage in Glycemic Control Among Patients With Gestational Diabetes Mellitus
This randomized controlled trial aims to compare the efficacy of Glucophage plus Myo-Inositol versus Glucophage alone in glycemic control among patients with gestational diabetes mellitus (GDM).
- Trial name
- NCT06840613
- Testing
- Myo-Inositol, Glucophage
- Volunteers
- 90 people
- Sponsor
- University of Health Sciences Lahore
Diabetes, Gestational, Pre-eclampsia
Usability Evaluation of Gen AI-based Nutrition Chatbot for Pregnant Women
Background: Pregnancy imposes significant physical demands, with complications like gestational diabetes (GDM) and pre-eclampsia posing serious risks.
- Conditions
- Diabetes, Gestational, Pre-eclampsia, AI Chatbot for Prenatal Nutrition Guidance
- Trial name
- NCT07458997
- Testing
- a culturally tailored nutrition AI chatbot for pregnant women
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Hong Kong Metropolitan University