Clinical trials: Diabetes Management
Type 2 Diabetes Mellitus
Effect of Insulin Degludec Versus Insulin Glargine on Glycemic Variability in Patients With Type 2 Diabetes Mellitus
Type 2 diabetes mellitus (T2DM) is characterized by wide fluctuations of glucose. The long-acting insulin has showed to improve glycemic variability however the behavior of insulin glargine versus insulin degludec is unknown.
- Trial name
- Diabetes (NCT02680457)
- Testing
- Insulin Degludec, Insulin Glargine
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- University of Guadalajara
Diabetes Mellitus
Improving Diabetes Care:Effectiveness of Physician Profiling and Care Coordination by a Diabetes Resource Nurse
The purpose of this study is to test the effectiveness of physician profiling and care coordination by a diabetes resource nurse in improving the quality of diabetes care.
- Trial name
- NCT00258674
- Testing
- Medicare Claims Feedback, Medical Record Review, Diabetes Resource Nurse
- Where
- United States
- Volunteers
- 1,891 people
- Sponsor
- Baylor Research Institute
Diabetes
Mobile Diabetes Management
The Mobile Diabetes Intervention Study trial is evaluating a diabetes coaching system, using mobile phones and patient/ physician internet portals to allow patient-specific treatment and communication by their primary care…
- Trial name
- NCT01107015
- Testing
- Tailored Patient Intervention, Patient-physician intervention, Patient and PCP intervention with analyzed data
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- University of Maryland, Baltimore
Diabetes, Diabetes Distress
Tailored Approaches to Reduce Distress and Improve Self-Management for Veterans With Diabetes
Veterans with diabetes may become overwhelmed with the self-management behaviors needed to maintain optimal health. Veterans may experience diabetes distress (DD), a concept distinct from depression, due the amount and frequency…
- Conditions
- Diabetes, Diabetes Distress, Self-Management, Veteran
- Trial name
- TARDIS (NCT04587336)
- Testing
- Cognitive Interview, Baseline Survey, Qualitative Interviews
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- VA Office of Research and Development
Diabetes Mellitus, Type 2
PROmoting Diabetes Education and Management Through Peer Support and Team Referral
A 3-step project is proposed. Step 1 will test which BPA time point(s) maximize referral rates to DSMES services in the real world clinic setting (Aim 1).
- Trial name
- PROMPT (NCT05587348)
- Testing
- Best Practice Advisory, Peer Support, Usual Care
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of North Carolina, Chapel Hill
Diabetic Macular Edema
Study of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) in Patients With Diabetic Macular Edema
The purpose of this study is to determine the efficacy of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) on the best corrected visual acuity (BCVA) assessed by the early treatment diabetic retinopathy study (ETDRS)…
- Trial name
- VISTA DME (NCT01363440)
- Testing
- Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321), Macular Laser Photocoagulation
- Where
- 51 sites in United States
- Volunteers
- 466 people
- Sponsor
- Regeneron Pharmaceuticals
Hypertension, Arthritis
The Health Access and Recovery Peer Program
Individuals with serious mental illnesses (SMI) face high rates of medical comorbidity as well as challenges in managing these conditions.
- Conditions
- Hypertension, Arthritis, Coronary Artery Disease, Hepatitis
- Trial name
- HARP (NCT01725815)
- Testing
- HARP Intervention
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Emory University
Diabetes
Diabetes Outcomes and Unmet Resources
This study will refine and test the effectiveness of CareAvenue, an automated e-health tool that informs and activates patients with uncontrolled diabetes to take steps in accessing resources and engaging in self-care.
- Trial name
- NCT03950973
- Testing
- CareAvenue, Guest Assistance Program
- Where
- United States
- Volunteers
- 667 people
- Sponsor
- University of Michigan
Diabetes Mellitus, Hypertension
The Impact of Sharing Audio Recorded Clinic Visits on Self-management in Older Adults
The investigators will conduct a multi-site, two-arm, parallel-group, patient-randomized, blocked, controlled, pilot trial with a 3-month follow up in older adults (≥65 years) with diabetes and hypertension.
- Trial name
- NCT04344301
- Testing
- Audio recording
- Where
- 3 sites in United States
- Volunteers
- 91 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Type 1 Diabetes
Self-Management in Young Adults With Type 1 Diabetes
Type 1 Diabetes (T1D) affects 1.6 million Americans, and only 14% of young adults age 18-25 years achieve glycemic targets (glycosylated hemoglobin A1C <7.0%).
- Trial name
- SLEEPT1D (NCT04975230)
- Testing
- Sleep Self-Management
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Case Western Reserve University
Chronic Renal Impairment, Diabetes Mellitus
Renal Safety of Iopamidol Versus Iodixanol During Coronary Angiography in Diabetic Patients
The purpose of this study is to compare the incidence of contrast-induced nephropathy (CIN) following the administration of iopamidol-370 (Iopamiro-370) and iodixanol-320 (Visipaque 320) in patients with moderate-to-severe…
- Trial name
- RECARE (NCT00782639)
- Testing
- Iopamidol injection 76%, iodixanol
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Bracco Diagnostics, Inc
Diabetes, Diabetes Mellitus, Type 2
To Compare the Effect of Liraglutide When Given Together With Metformin With the Effect of Metformin Given Alone and With the Effect of Glimepiride and Metformin Given Together
This trial is conducted in Europe, Oceania, Africa, Asia and South America. This trial is designed to show the effect of treatment with liraglutide when adding to existing metformin therapy and to compare it with the effects of…
- Trial name
- LEAD-2 (NCT00318461)
- Testing
- liraglutide, metformin, glimepiride
- Where
- 190 sites in Argentina, Australia and 18 more
- Volunteers
- 1,091 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes
The Breakfast Study
The investigators conducted an acceptability, feasibility, preliminary effectiveness trial of a 4-month, online, very low-carbohydrate breakfast-focused program in 120 adults with type 2 diabetes.
- Trial name
- NCT05986097
- Testing
- Breakfast
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- University of Michigan
Diabetes Mellitus
Mobile Insulin Titration Intervention
The purpose of this pilot study is to determine whether text message (and phone) communication can be effectively utilized to adjust long-acting insulin, compared to standard practice.
- Trial name
- MITI (NCT01879579)
- Testing
- Mobile Insulin Titration Intervention
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- NYU Langone Health
Diabetes, Effects of Liraglutide Administration on Brain Activity
Liraglutide in Obesity and Diabetes: Identification of CNS Targets Using fMRI
The main purpose of this study is to help us understand the effects of diabetes medication Liraglutide on weight loss and hunger.
- Conditions
- Diabetes, Effects of Liraglutide Administration on Brain Activity, Weight Loss, Hunger
- Trial name
- NCT01562678
- Testing
- Liraglutide
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Beth Israel Deaconess Medical Center
Diabetes Mellitus, Type 2
Diabetes Disparities: Texting to Extend Treatment (DD-TXT)
One way to help Veterans improve their diabetes control is through the use of technology to help provide information, motivation, and reminders necessary to support diabetes self-management.
- Trial name
- DD-TXT (NCT04227379)
- Testing
- Intervention 1- DSMS+, Comparison - DSMS
- Where
- 3 sites in United States
- Volunteers
- 366 people
- Sponsor
- VA Office of Research and Development
Type2 Diabetes
Stories for Change: Digital Storytelling for Diabetes Self-Management Among Hispanic Adults
Hispanic adults are twice as likely to have type 2 diabetes mellitus (T2D) and 1.5 times more likely to die from the disease than non-Hispanic whites.
- Trial name
- S4C (NCT03766438)
- Testing
- Digital Storytelling Intervention
- Where
- 3 sites in United States
- Volunteers
- 451 people
- Sponsor
- Mayo Clinic
Diabetes Mellitus, Type 2
Use of iPro™2 in Real Life Diabetes Management of Type 2 Patients in India
The purpose of the India iPro2 study is to demonstrate that iPro2 Continuous Glucose Monitoring System (CGMS) evaluation enables Health Care Professional (HCP)s treating patients in India with type 2 diabetes to get a better…
- Trial name
- NCT01995539
- Testing
- therapy regimen
- Where
- 11 sites in India
- Volunteers
- 181 people
- Sponsor
- Medtronic MiniMed, Inc.
Diabetes Mellitus
MEDTRUM A7+ TouchCare Insulin Patch Pump (MedInPS)
Demonstration study of the interest of the MEDTRUM A7+ TouchCare insulin patch pump versus INSULET Omnipod® patch pump
- Trial name
- MedInPS (NCT04223973)
- Testing
- Medtrum A7+ insulin Pump, Lab A1C
- Where
- France
- Volunteers
- 93 people
- Sponsor
- Medtrum France
Diabetes
Jump Start Shared Medical Appointments for Diabetes With Weight Management
The proposed research will test a novel program that combines intensive weight management with shared (group) medical appointments for patients with diabetes.
- Trial name
- Jump Start (NCT01973972)
- Testing
- Weight management, Shared medical appointments (SMA)
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- VA Office of Research and Development