Clinical trials: Diabetes Mellitus, Experimental
Diabetes Mellitus Type I, Ketoacidosis
Metabolic Signalling in Muscle- and Adipose-tissue Following Insulin Withdrawal and Growth Hormone Injection.
Diabetes mellitus type I (DM I) is characterized by lack of endogenous insulin and these patients are 100% dependent on insulin substitution to survive.
- Trial name
- NCT02077348
- Testing
- Insulin withdrawal, Norditropin
- Where
- Denmark
- Volunteers
- 9 people
- Sponsor
- University of Aarhus
Diabetes, Anemia
A Study to Compare Analytes in Blood Collected Using an Investigational Collection Device With a Commercial Predicate
This study will involve an investigational device, the Seventh Sense Biosystems TAP20-C. The TAP20-C device collects small amounts of blood from the forearm which can then be used for blood testing.
- Trial name
- NCT01786408
- Testing
- TAP20-C, SAFE-T-FILL CAPILLARY BLOOD COLLECTION SYSTEM
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Seventh Sense Biosystems
Diabetes
Performance of an Investigational Blood Glucose Monitoring System in a Clinical Setting
The purpose of this study is to evaluate the performance of an investigational blood glucose meter with the Contour sensor strip.
- Trial name
- NCT01268488
- Testing
- Ninja 2 Investigational Blood Glucose Meter
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Ascensia Diabetes Care
Diabetes Type 2, Diabetes Mellitus, Experimental
Phase-III Clinical Studies on Poly Herbal Anti-Diabetic Formulation
The goal of this clinical trial to learn the clinical efficacy and safety of standardized polyherbal capsule weighing around 500 mg, containing Syzygium cumini, Momordica charantia, Wrightia tinctoria, and Gymnema sylvestre in…
- Conditions
- Diabetes Type 2, Diabetes Mellitus, Experimental, HbA1c, Urinary Glucose
- Trial name
- NCT07279909
- Testing
- DIAB-PHC1, Metformin
- Where
- Pakistan
- Volunteers
- 500 people
- Sponsor
- Hamdard University
Diabetic Ketoacidosis
Impact of Clinical Nursing Guideline on Outcomes of Children With Diabetic Ketoacidosis.
Diabetic ketoacidosis (DKA) is a serious and potentially life-threatening complication of diabetes mellitus in children and requires timely and structured management to prevent morbidity and mortality.
- Trial name
- PED-DKA (NCT07467616)
- Testing
- Evidence-Based Nursing Guideline for Children with Diabetic Ketoacidosos
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- Hawler Medical University
Diabetes
Performance of an Investigational Blood Glucose Monitoring System
The purpose of this study was to demonstrate that untrained subjects who have diabetes can operate the Investigational Blood Glucose Monitoring System (BGMS) and obtain valid glucose results.
- Trial name
- NCT01824355
- Testing
- Ninja 3 PLUS Investigational BG Monitoring System
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Ascensia Diabetes Care
Diabetes
User Study of an Investigational Blood Glucose Monitoring System
This clinical trial is designed to assess an investigational blood glucose monitoring system with fingerstick blood in the hands of untrained intended users.
- Trial name
- NCT01447121
- Testing
- Tatsu/Tradewind Investigational BG Monitoring System
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Ascensia Diabetes Care
Ketoacidosis, Diabetes Mellitus Type 1
A Study of Intracellular Signaling in Muscle and Fat Cells During Ketosis
Hypothesis 1. To define whether stimulation of ATGL and suppression of G0/G1 switch gene occur in the initial phases of diabetic ketoacidosis and thus can be identified as the primary mechanisms behind this life threatening…
- Trial name
- NCT02157155
- Testing
- LPS
- Where
- Denmark
- Volunteers
- 9 people
- Sponsor
- University of Aarhus
Diabetes
Evaluation of an Karajishi TS Investigational Blood Glucose Monitoring System
The purpose of this study was to determine if subjects who have diabetes can operate the Investigational Blood Glucose Monitoring System (BGMS) with no training and obtain valid glucose results.
- Trial name
- NCT02041377
- Testing
- Karajishi TS Investigational Blood Glucose Monitoring System
- Where
- 2 sites in United States
- Volunteers
- 134 people
- Sponsor
- Ascensia Diabetes Care
Diabetes, Congenital Heart Disease
The Roles of Trust and Respect in Patient Reactions to Race-based and Personalized Medicine Vignettes: An Experimental Study
Background: Genetic research has implications for drug development and marketing. Race-based medicine may be able to provide specific treatment for populations with increased disease-specific morbidity and mortality.
- Conditions
- Diabetes, Congenital Heart Disease, Hypertension
- Trial name
- NCT00911833
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Type 2 Diabetes Mellitus (T2DM), Diabetes Self-Management Education
Effects of Online Diabetes Self-management Education on Knowledge Retention, BMI, and HbA1c in Newly Diagnosed Adults With Type 2 Diabetes
Type 2 diabetes requires active self-management from the time of diagnosis, but participation in traditional face-to-face diabetes self-management education is often limited by access-related and personal barriers.
- Trial name
- NCT07669038
- Testing
- Online Diabetes Self-Management Education, Traditional Face-to-Face Diabetes Self-Management Education
- Where
- Slovenia
- Volunteers
- 123 people
- Sponsor
- University of Primorska
Diabetes
Evaluation of an Investigational Blood Glucose Monitoring System
The purpose of this study was to determine if untrained subjects who have diabetes can operate the Investigational Blood Glucose Monitoring System (BGMS) and obtain valid glucose results.
- Trial name
- NCT01859494
- Testing
- NINJA 3 Investigational Blood Glucose Monitoring System
- Where
- 2 sites in United States
- Volunteers
- 219 people
- Sponsor
- Ascensia Diabetes Care
Diabetes, Anemia
A Study to Compare Analyte Levels in Blood Collected Using an Investigational Collection Device With a Commercial Predicate
This study will compare blood collection from the forearm using an investigational device, TAP20-C to blood collection from the finger tip.
- Trial name
- NCT01934842
- Testing
- TAP20-C, SAFE-T-FILL
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Seventh Sense Biosystems
Type 2 Diabetes Mellitus
An Investigational Drug Study in Adults With Type 2 Diabetes on Basal Insulin (MK-0941-006)
A study to assess safety, pharmacokinetics (PK), and pharmacodynamics (PD) of MK-0941 in Type 2 diabetics being treated with basal insulin.
- Trial name
- NCT00511472
- Testing
- MK-0941, LANTUS insulin
- Volunteers
- 70 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Type 2
Study To Understand Efficacy And Safety Of Investigational Agent (PF-04937319) Compared To Approved Agent (Glimepiride) In Patients With Diabetes On Metformin
This is a study to understand efficacy and safety of investigational agent (PF-04937319) compared to approved agent (glimepiride) in patients with diabetes on metformin
- Trial name
- NCT01517373
- Testing
- PF-04937319 10 mg, PF-04937319 50 mg, PF-04937319 100 mg
- Where
- 53 sites in United States, Bulgaria and 5 more
- Volunteers
- 304 people
- Sponsor
- Pfizer
Diabetes Mellitus, Type 2
A Study To Evaluate The Safety And Efficacy Of An Investigational Diabetes Drug In Poorly Controlled Type II Diabetics
The purpose of this research study is to determine if a new investigational diabetes drug is safe and effective in treating people who have Type II diabetes mellitus with very high HbA1c or FPG (fasting plasma glucose) levels.
- Trial name
- NCT00067951
- Testing
- rosiglitazone/metformin
- Where
- 94 sites in United States, Australia and 3 more
- Volunteers
- 190 people
- Sponsor
- GlaxoSmithKline
Type2 Diabetes, Sleep
Experimental Changes in Children's Sleep Duration and Timing: Effect on Obesity and Type 2 Diabetes Risk
Enhancing children's sleep duration and/or timing may represent a novel approach for weight regulation and prevention of T2DM. The proposed study will assess how experimental changes in children's sleep duration and timing affect…
- Trial name
- NCT02979860
- Testing
- Sleep duration 90 min, Sleep duration 45 min, Sleep timing
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Temple University
Diabetes
User Performance Evaluation of an Investigational Blood Glucose Monitoring System
The purpose of this study is to demonstrate that untrained subjects with diabetes can use an investigational Blood Glucose Monitoring System (BGMS) with capillary blood obtained from fingerstick and from Alternative Site (AST)…
- Trial name
- NCT01410773
- Testing
- Ninja 2 Investigational Blood Glucose Monitoring System
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Ascensia Diabetes Care
Type 1 Diabetes
Insulin Pump-RT Advisor (IPRA©): a Decision Support Software for Diabetic Patients Treated by Insulin Pump and Using Continuous Glucose Monitoring. Experimental Study. Evaluation by an Expert Patient Panel.
The purpose of the study is to assess the relevance of the advices provided by the IPRA© smartphone application for guiding the responses of insulin pump treated type 1 diabetes patients using real-time continuous glucose…
- Trial name
- IPRA (NCT01883024)
- Testing
- A decision support software, Insulin Pump, Continuous glucose monitoring
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Rennes University Hospital
Diabetes Mellitus, Insulin-Dependent, Diabetes Mellitus, Experimental
hOKT3gamma1 (Ala-Ala) for the Prevention of Human Islet Allograft Failure
The broad, long-term goal of this proposal is to improve the results and applicability of islet allotransplantation early in the course of type 1 diabetes through the administration of selective and short-term immunotherapy.
- Conditions
- Diabetes Mellitus, Insulin-Dependent, Diabetes Mellitus, Experimental, Transplantation, Homologous, Islets of Langerhans Transplantation
- Trial name
- NCT00008801
- Testing
- hOKT3gamma1 (Ala-ala)
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)