Clinical trials: Diabetes Mellitus, Experimental, open to volunteers
Prediabetes / Type 2 Diabetes
A Clinical Trial to Examine the Efficacy and Safety of an Investigational Product With and Without Use of Semaglutide on Glycemic Response in Adults With Prediabetes or Type 2 Diabetes
This is a randomized, single-blind, controlled, parallel clinical trial to examine the efficacy and safety of AMPK Charge+® with and without use of semaglutide on glycemic response in adults with prediabetes or Type 2 Diabetes.
- Trial name
- NCT07195994
- Testing
- AMPK Charge+®, AMPK Charge+® with semaglutide
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- QuickSilver Scientific
Type 2 Diabetes, Type 2 Diabetes Patients
The Effect of Education Given to Type 2 Diabetics on Diabetes Self-management, Health Fatalism and Metabolic Parameters
This study aims to examine the effects on diabetes self-management, health fatalism and metabolic parameters of individuals with type 2 diabetes.
- Trial name
- NCT06769477
- Testing
- Experimental Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Cardiovascular Risk Factors, Hypertension
Clinical Management of Cardiovascular Risk Factors in Adult Patients: A Before-and-After Interventional Study
This study aims to evaluate cardiovascular risk factors, clinical characteristics, and outcomes in adult patients attending an outpatient cardiology clinic.
- Conditions
- Cardiovascular Risk Factors, Hypertension, Dyslipidemia, Type 2 Diabetes Mellitus
- Trial name
- CV-RISK (NCT07447362)
- Testing
- Structured Cardiovascular Risk Management
- Where
- Chile
- Volunteers
- 220 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Non-Small Cell Lung Cancer
Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer
This first-in-human (FIH) study for BNT116 aims to establish the safety profile and a safe dose for BNT116 monotherapy as well as for BNT116 in combination with approved medicinal products and/or in combination with…
- Trial name
- LuCa-MERIT-1 (NCT05142189)
- Testing
- BNT116, Cemiplimab, Docetaxel
- Where
- 45 sites in United States, Australia and 6 more
- Volunteers
- 320 people
- Sponsor
- BioNTech SE
Diabetic Foot Ulcer (DFU)
A Study Comparing an Investigational Wound Gel With Standard Treatment for Mild to Moderate Diabetic Foot Ulcers
The goal of this clinical investigation is to evaluate if VES-0-D (an investigational wound gel) works to treat mild to moderate Diabetic Foot Ulcers.
- Trial name
- AIM-DFU (NCT07783087)
- Testing
- VES-0-D wound gel, Standard of Care (Investigator Choice)
- Where
- 8 sites in Belgium
- Volunteers
- 64 people
- Sponsor
- Flen Health
Type 2 Diabetes, Sedentary Behaviors
Protocol for a Quasi-experimental Controlled Study to Reduce Sedentary Lifestyle in Patients With Type 2 Diabetes
The prevalence of diabetes has increased worldwide, making it the most prevalent metabolic disorder. Physical inactivity contributes to the progression of this disease and aggravates other comorbidities, such as obesity and…
- Trial name
- NCT06893146
- Testing
- Reduction of Sedentary Behavior, Educational support
- Volunteers
- 169 people
- Sponsor
- University of La Rioja
Diabetes, Gestational, Pre-eclampsia
Usability Evaluation of Gen AI-based Nutrition Chatbot for Pregnant Women
Background: Pregnancy imposes significant physical demands, with complications like gestational diabetes (GDM) and pre-eclampsia posing serious risks.
- Conditions
- Diabetes, Gestational, Pre-eclampsia, AI Chatbot for Prenatal Nutrition Guidance
- Trial name
- NCT07458997
- Testing
- a culturally tailored nutrition AI chatbot for pregnant women
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Hong Kong Metropolitan University
Atrial Fibrillation (AF), Heart Failure
Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
People with severe mental illness have a substantially increased risk of undiagnosed and insufficiently treated somatic disease.
- Conditions
- Atrial Fibrillation (AF), Heart Failure, Asthma (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- SomaScreen (NCT07518446)
- Testing
- Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
- Where
- Denmark
- Volunteers
- 2,800 people
- Sponsor
- Amager Hospital
Type 1 Diabetes (T1D)
Evaluation of the Safety and Effectiveness of the Novel Medtronic Experimental Automated Insulin Delivery System (NMX8) in Adults Living With Type 1 Diabetes
The purpose of the study is to evaluate the safety and the effectiveness of the Novel Medtronic Experimental Automated Insulin Delivery system, named MiniMed NMX8 system (referred also to as NMX8 system), in comparison with other…
- Trial name
- ELEVATE (NCT07401901)
- Testing
- NMX8 System - Treatment arm, AID Therapy, NMX8 System - Control Arm
- Where
- 21 sites in France, Germany and 4 more
- Volunteers
- 230 people
- Sponsor
- Medtronic MiniMed, Inc.
Diabete Mellitus, Diabetes Knowledge Score
Telemedicine-Based Behavioral Intervention to Improve Outcomes Among Diabetic Patients
The goal of this quasi-experimental clinical study is to learn whether a telemedicine-based behavioral intervention can improve health outcomes among adult patients with diabetes receiving care at tertiary hospitals in Northwest…
- Trial name
- NCT07423351
- Testing
- Telemedicine-Based Diabetes Self-Management Counseling
- Volunteers
- 320 people
- Sponsor
- Bahir Dar University
Self-management, Type 2 Diabetes Mellitus (T2DM)
Development and Evaluation of a Culturally Sensitive Structured Diabetes Self-Management Program for People With Type 2 Diabetes Residing in Qatar
This study is about helping people in Qatar who have Type 2 Diabetes take better care of their health. Diabetes is a common and growing problem in Qatar, and many people need more support and information to manage it well in…
- Conditions
- Self-management, Type 2 Diabetes Mellitus (T2DM), Diabetes Self-management
- Trial name
- PARADIGM-Q (NCT06948370)
- Testing
- Intervention Name: PARADIGM-Q Diabetes Self-Management Education Program, Control Arm (DESMOND): DESMOND Diabetes Self-Management Education Program
- Volunteers
- 200 people
- Sponsor
- Ragae Dughmosh
Diabetes (Insulin-requiring, Type 1 or Type 2)
Evaluation of the Safety and Performance of the Novel Medtronic Experimental Automated Insulin Delivery System (NMX8) in People Living With Diabetes (NEXUS)
This study will demonstrate the safety and performance of the Novel Medtronic Experimental Automated Insulin Delivery system named MiniMed™ NMX8 system in people living with insulin-requiring diabetes in comparison with the…
- Trial name
- NEXUS (NCT07227805)
- Testing
- NMX8, 780G
- Where
- 9 sites in Belgium, Denmark and 2 more
- Volunteers
- 116 people
- Sponsor
- Medtronic MiniMed, Inc.
Diabetes in Children, Diabetes Type 1
Intelligent Care Platform - Quasi-Experimental Trial
This study will measure the implementation and effectiveness of an intervention, the use of a digital health tool, Haibu Diabetes, for the management of pediatric type 1 diabetes (T1D), on clinical outcomes.
- Trial name
- UBColumbia (NCT07712809)
- Testing
- Digital Diabetes Care Platform
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia