Clinical trials: Diabetes Mellitus (DM), active
Type 2 Diabetes Mellitus (DM)
Community-based, eHealth Supported Type 2 Diabetes Care by Lay Village Health Workers in Rural Lesotho
This cluster-randomized intervention is embedded in the ComBaCaL (Community-Based Chronic disease care Lesotho) cohort study (EKNZ ID AO_2022-00058, clinicaltrials.gov ID NCT05596773, Lesotho NH-REC ID 210-2022), a platform for…
- Trial name
- ComBaCaL DM (NCT05743387)
- Testing
- DM care package, Referral to the responsible health facility
- Where
- 2 sites in Lesotho, Switzerland
- Volunteers
- 252 people
- Sponsor
- University Hospital, Basel, Switzerland
Pre Diabetes, Diabetes (DM)
Preventing Diabetes: Impact of an EMR-Based Intervention for Enhanced Pre-Diabetes Management in Primary Care
The goal of this study is to find out if adding electronic medical record (EMR) prompts helps prevent people with pre-diabetes from developing diabetes. It will also look at how these prompts affect doctor and patient behaviors.
- Trial name
- NCT07252700
- Testing
- Electronic Medical Record-Based Clinical Decision Support
- Where
- Singapore
- Volunteers
- 6,000 people
- Sponsor
- Lynette Goh
Cardio Vascular Disease, Diabetes (DM)
Holistic CRM Care vs Standard of Care in a Primary Care Setting
Cardiovascular disease, high blood pressure, chronic kidney disease, and type 2 diabetes, collectively referred to as Cardio-Renal-Metabolic (CRM) conditions, are among the most common chronic diseases in society.
- Conditions
- Cardio Vascular Disease, Diabetes (DM), Chronic Kidney Disease
- Trial name
- HOPE-CRM (NCT07819383)
- Testing
- CRM care
- Volunteers
- 6,000 people
- Sponsor
- Danderyd Hospital
Peri Implant Mucositis, Peri Implant Bone Loss
Local and Systemic Inflammatory Bone Alterations Related to Dental Implant Survival.
Introduction: Dental implants offer a durable, aesthetic, and functional option for tooth replacement. However, they are not immune to failure.
- Conditions
- Peri Implant Mucositis, Peri Implant Bone Loss, Peri Implantitis, Calcium Deficiency
- Trial name
- NCT07766707
- Where
- Spain
- Volunteers
- 192 people
- Sponsor
- University of Barcelona
Diabetes (DM), Vitamin D Deficiency
Comparison of Different Doses of Vitamin D Supplementation on Glycated Haemoglobin and Blood Glucose Parameters With Type II Diabetes Mellitus Having Vitamin d Deficiency
COMPARISON OF DIFFERENT DOSES OF VITAMIN D SUPPLEMENTATION ON GLYCATED HEMOGLOBIN (HbA1c) and BLOOD GLUCOSE PARAMETRS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS HAVING VITAMIN D DEFICIENCY"
- Trial name
- NCT07321223
- Testing
- Vitamin D
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- University of Lahore
Diabetes, Diabetes (DM)
Time in rANge vs. Time in nOrmal Glycemia for Better Glycemic Control
The TANGO study is a 12-month study involving 120 children and adolescents with Type 1 Diabetes (T1D) across the Czech Republic, Israel, and Poland who use automated insulin delivery (AID) systems.
- Conditions
- Diabetes, Diabetes (DM), Diabetes Type 1
- Trial name
- TANGO (NCT07376850)
- Testing
- Structured Diabetes Education, Automated Insulin Delivery (AID) System Adjustment
- Where
- 3 sites in Czechia, Israel and 1 more
- Volunteers
- 120 people
- Sponsor
- University Hospital, Motol
Diabetes Mellitus in Pregnancy, Type 2 Diabetes Mellitus (T2DM)
RCT Glargine vs NPH for Treatment of DM in Pregnancy
We are asking you to take part in this research study because you are diagnosed with pregestational Type 2 Diabetes Mellitus or Gestational Diabetes Mellitus requiring insulin therapy in pregnancy.
- Conditions
- Diabetes Mellitus in Pregnancy, Type 2 Diabetes Mellitus (T2DM), Gestational Diabetes Mellitus, Class A2
- Trial name
- NCT06619301
- Testing
- Insulin glargine, insulin NPH
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Loyola University
Diabete Type 2, Heart Failure
Monitoring of the Sympathetic/Vagal Balance Through Multiparametric Analysis of Heart Rate Variability (HRV)
The autonomic nervous system (ANS) plays a crucial role in cardiovascular regulation by modulating heart rate in response to endogenous and environmental stimuli.
- Conditions
- Diabete Type 2, Heart Failure, Kidney Disease, Chronic, Cardiorenal Syndrome
- Trial name
- GLIFO-HRV (NCT07471802)
- Testing
- HOLTER ECG monitoring
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Type 2 Diabetes
Joint Patient and Caregiver Intervention for Older African Americans With Type 2 Diabetes
This study will test the preliminary efficacy of a joint patient/informal caregiver telephone-delivered intervention that includes diabetes education; problem solving around social needs; and behavioral activation for older…
- Trial name
- NCT06279637
- Testing
- Joint Home-DM-BAT Intervention, Usual Care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Medical College of Wisconsin
Hypertension (HTN), Diabetes (DM)
Team-Based Shared Decision-Making Program in Cardiovascular-Kidney-Metabolic Health (Healthy Heart - CKM)
The investigators are proposing a new team-based shared decision-making (SDM) program. The goal of this study is to see whether this program is practical and whether it may help adults with cardiometabolic risk factors and…
- Conditions
- Hypertension (HTN), Diabetes (DM), Hyperlipidaemia, Kidney Disease
- Trial name
- SDM in CKM (NCT07662616)
- Testing
- Team-based shared decision-making
- Volunteers
- 94 people
- Sponsor
- Johns Hopkins University
Type 2 DM
Telehealth-Based Chronic Disease Management for Type 2 Diabetes
This study will be conducted from enrollment until the end of the six-month follow-up period. This study aims to assess the impact of the Internet hospital online + offline integrated chronic disease management model on patients…
- Trial name
- T2DMTH (NCT06719050)
- Volunteers
- 1,636 people
- Sponsor
- Zeng Lin, Ph. D.
Diabetes Mellitus (DM)
This Study is Conducted to Evaluate the 18-month Clinical Performance of Complete Bioactive Restorative System for Occlusal Restorations Between Diabetic and Non-diabetic Patients.
This study is conducted to evaluate the 18-month clinical performance of complete bioactive restorative system for occlusal restorations between diabetic and non-diabetic patients.
- Trial name
- NCT07432724
- Testing
- bioactive composite
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Type 2 Diabetes
Lowering the Impact of Food Insecurity in African American Adults With Type 2 Diabetes Mellitus (LIFT-DM)
The objective of this protocol is to answer the questions: 1) Within food supplementation options, are mailed stock boxes superior to food vouchers in terms of achieving glycemic control? 2) Is the combination of mailed stock…
- Trial name
- LIFT-DM (NCT04181424)
- Testing
- Diabetes Education Plus Monthly Food Vouchers, Diabetes Education Plus Combination of Monthly Food Vouchers and Stock Boxes, Diabetes Education Only
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- State University of New York at Buffalo
DM
Impact of P53 and SIRT1 in Type 2 Diabetes
Investigating the impact of p53 and SIRT1 in the development of type 2 DM
- Trial name
- NCT03925714
- Testing
- life style, Metformin, Nigetella salivata
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Sherief Abd-Elsalam
Type 2 Diabetes, Mental Health
Technology-Enabled Collaborative Care for Diabetes and Mental Health
Managing both type 2 diabetes and mental health challenges can be difficult, and many people do not receive care that supports both.
- Conditions
- Type 2 Diabetes, Mental Health, Diabetes Distress
- Trial name
- TECC-DM (NCT07181863)
- Testing
- Health coaching, Educational emails
- Where
- 2 sites in Canada
- Volunteers
- 160 people
- Sponsor
- McMaster University
Coronary Heart Disease (CHD), Diabetes (DM)
A Prospective Multicenter Clinical Study： IntracOronary neaR-Infrared Spectroscopy and OptIcal Coherence Tomography for Evaluating Coronary vulNerable Plaque in Patients With diabeTes
To evaluate the correlation between maxLCBI4mm/FCTmin(a new index of lipid plaque based on NIRS-OCT technology) and fiber cap thickness , and the prognosis of patients, providing a new quantitative index for early, accurate and…
- Trial name
- NCT06649305
- Where
- China
- Volunteers
- 1,516 people
- Sponsor
- Shanghai Zhongshan Hospital
Diabetic Foot Ulcer, Diabetes Mellitus (DM)
Evaluating the Efficacy of Pulsating Electromagnetic Field Therapy by CRAD ULCER X-01 for Diabetic Foot Ulcers
Background: Diabetic foot ulcer (DFU) is a frequent complication of chronic, uncontrolled diabetes mellitus (DM). Treatment with antibiotics, daily dressing, wound debridement, and wound off-loading is often prescribed.
- Trial name
- NCT07465640
- Testing
- Pulsating electromagnetic field
- Where
- Malaysia
- Volunteers
- 32 people
- Sponsor
- National Defence University of Malaysia
Peripheral Neuropathy, Painful Neuropathy
Earlier Diagnosis of Peripheral Neuropathy Using A Simple sCreening Tool (ACT)
This study is looking at people with diabetes (type 1 and type 2 diabetes) to see how well a short questionnaire, called the ACT, can identify nerve damage in the feet and legs (also known as peripheral neuropathy).
- Conditions
- Peripheral Neuropathy, Painful Neuropathy, Diabetes (DM)
- Trial name
- ACT (NCT07163000)
- Where
- Qatar
- Volunteers
- 150 people
- Sponsor
- Weill Cornell Medical College in Qatar
Diabetes (DM)
Digital Discharge Planning to Improve Self-Management in Patients With Diabetes Mellitus
Diabetes mellitus is a chronic disease that requires continuous self-management to prevent complications and hospital readmissions.
- Trial name
- DDP-DM (NCT07515677)
- Testing
- Digital Discharge Planning Application, Standard Discharge Planning
- Where
- Indonesia
- Volunteers
- 78 people
- Sponsor
- Universitas Muhammadiyah Surakarta
Diabetic Foot Disease, Diabetic Foot Infection
Continuous Monitoring of Plantar Temperature Variations Using Connected Insoles and a Mobile Application for Diabetic Foot.
The goal of this clinical trial is to evaluate the performance of a self-monitoring system (Solsius SelfCare) to detect pre-ulcerative clinical abnormalities in adults living with type 1 or 2 diabetes at high podiatric risk…
- Conditions
- Diabetic Foot Disease, Diabetic Foot Infection, Diabetic Foot Infections, Diabete Type 1
- Trial name
- DIAFOOTEM (NCT07910721)
- Testing
- Solsius SelfCare
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- Solsius