Clinical trials: Diabetes Mellitus II
Type II Diabetes Mellitus
A Non-Interventional Study To Evaluate Diabetes Related Quality Of Life, Frequency And Impact Of Hypoglycemia In T2DM
This is a non-interventional, cross sectional, multicentric study in T2DM patients which will involve a single visit for study related procedures.
- Trial name
- INSIGHT (NCT01523405)
- Where
- 70 sites in India
- Volunteers
- 4,911 people
- Sponsor
- AstraZeneca
Diabetes Mellitus Type II
Safety and Effects of Autologous Adipose-Derived Stromal Cells Delivered in Patients With Type II Diabetes
This will be an open-label, non-randomized, multi-center, patient sponsored study of Adipose-Derived Stromal vascular fraction cells implantation via intravenous infusion.
- Trial name
- NCT01453751
- Testing
- Harvesting and Implantation of Adipose-Derived Stromal Vascular Fraction (AD-SVF)
- Where
- United States
- Sponsor
- Ageless Regenerative Institute
Painful Diabetic Peripheral Neuropathy
A Clinical Trial to Study the Effects GRC 17536 in Patients With Painful Diabetic Peripheral Neuropathy (Painful Extremities Due to Peripheral Nerve Damage in Diabetic Patients).
Diabetic peripheral neuropathy (DPN) represents a diffuse symmetric and length-dependent injury to peripheral nerves that has major implications on quality of life (QOL), morbidity, and costs from a public health perspective.
- Trial name
- NCT01726413
- Testing
- GRC 17356
- Where
- 15 sites in Czechia, Germany and 2 more
- Volunteers
- 138 people
- Sponsor
- Glenmark Pharmaceuticals Ltd. India
Diabetes Mellitus, Type 2, Overweight and Obesity
Overweight and Obesity in Relation to Type ll Diabetes Melitus
The aim of the study is to evaluate the efficacy of local Zambian food in improving metabolic profiles of overweight/obese type ll diabetic patients in Kitwe district
- Trial name
- NCT04016012
- Testing
- Local Zambian Foods
- Where
- Zambia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mukuba University
Diabetic Neuropathy
ACUpuncture in Diabetic Peripheral Neuropathy
Multicentric,randomized, two-armed confirmatory trial on the effectiveness of acupuncture in patients with symptomatic peripheral diabetic neuropathy compared to routine care.
- Trial name
- ACUDPN (NCT03755960)
- Testing
- acupuncture, routine care
- Where
- 2 sites in Germany
- Volunteers
- 62 people
- Sponsor
- Benno Brinkhaus
Diabetes Mellitus, Hypertension
Integrated Hypertension and Diabetes Mellitus Type II Treatment and Care Among People Living With HIV/AIDS
This project was a facility-based program intervention for People Living with HIV (PLHIV) aged 18 years and above who attended a Care and Treatment Center (CTC) in Dar es Salaam, Tanzania.
- Conditions
- Diabetes Mellitus, Hypertension, HIV Infections
- Trial name
- NCT05786703
- Testing
- Biochemical, weight measurements, Blood pressure and blood sugar level
- Where
- Tanzania
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- Muhimbili University of Health and Allied Sciences
Type 1 Diabetes Mellitus
Clinical Phase II/III Trial of Ustekinumab to Treat Type 1 Diabetes (UST1D2)
In type 1 diabetes (T1D), immune defense cells in the body attack and destroy insulin-producing beta cells leaving affected people with a lifelong need for daily insulin injections.
- Trial name
- UST1D2 (NCT03941132)
- Testing
- Ustekinumab
- Where
- 2 sites in Canada
- Volunteers
- 66 people
- Sponsor
- University of British Columbia
Type II Diabetes Mellitus
The Use of a Computer Program to Help Primary Care Providers Treat Patients With Type 2 Diabetes
The primary purpose of this study is to determine whether the use of CADS by primary care providers (PCPs) for their patients with type 2 diabetes (T2DM) changes the quality of care relative to a "usual care" group in terms of…
- Trial name
- CADS (NCT01648244)
- Testing
- Computer-Assisted Decision Support
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Walter Reed National Military Medical Center
Type 2 Diabetes
A PK/PD Study of Polyethylene Glycol Loxenatide in Patients With Type 2 Diabetes
Polyethylene Glycol Loxenatide (PEX168) is a new human glucagon-like peptide 1 (GLP-1) analogue that created on the basis of the Exenatide and modified by polyethylene glycol (PEG).
- Trial name
- NCT01965509
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Diabetes Mellitus, Type 2, Diabetes Education
Impact of a Diabetes Education Mobile Web Application on Patients With Uncontrolled Type 2 Diabetes
The goal of this clinical trial is to evaluate the use and effectiveness of a mobile web application (app) that is designed to educate and allow patients to manage diabetes and make sustainable lifestyle changes, and to study the…
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Education, Lifestyle Modification
- Trial name
- NCT05893927
- Testing
- Diabetes education web site application
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- The Reading Hospital and Medical Center
Type2 Diabetes Mellitus, Obesity
Neujia Anastomosis for Treatment of Obesity and Type II Diabetes
This prospective, multicenter, open label, single arm study will enroll subjects presenting with obesity and inadequately controlled type II diabetes (T2DM).
- Trial name
- NEUJIA 1A (NCT03675074)
- Testing
- Neujia
- Sponsor
- Neurotronic, Inc.
Diabetes Mellitus
Acupuncture in the Complementary Treatment of Diabetes Mellitus Type II
This is a randomized clinical research, with triple blinded multicenter involving the Federal University of Rio de Janeiro, through the School of Nursing Anna Nery, as a proponent and research coordinator; and as a collaborative…
- Trial name
- ACT-DM (NCT02605889)
- Testing
- Laser acupuncture
- Where
- Brazil
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- NEIDE APARECIDA TITONELLI ALVIM
Diabetes Mellitus, Type 2
BI 1356 BS in Japanese Patients With Type 2 Diabetes Mellitus
Study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of BI 1356 BS (0.5 mg, 2.5 mg, and 10 mg) administered orally once daily for 28 days in Japanese patients with type 2 diabetes mellitus.
- Trial name
- NCT02183324
- Testing
- Low dose of BI 1356 BS, Medium dose of BI 1356 BS, High dose of BI 1356 BS
- Volunteers
- 72 people
- Sponsor
- Boehringer Ingelheim
Diabetes Mellitus, Type 2, Cognitive Impairment
Diabetes and Cognitive Functions in Middle Age
This study will examine the effects of type II diabetes on cognitive functions and mood in middle-aged patients. In addition, the association between cognitive functions and glycemic controls is studied in patients.
- Conditions
- Diabetes Mellitus, Type 2, Cognitive Impairment, Hyperglycemia, Hypoglycemia
- Trial name
- DBC (NCT05919927)
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Diabetic Ulcers
Safety and Efficacy of Vasculera® in the Healing of Diabetic Skin Ulcers
This study is designed to evaluate if Vasculera, a marketed medical food product, will improve the rate and extent of healing of diabetic ulcers.
- Trial name
- NCT02361437
- Testing
- Vasculera
- Where
- United States
- Sponsor
- Primus Pharmaceuticals
Diabetic Complication
YJP-14 Capsules for the Treatment of Endothelial Dysfunction in Patients With Diabetes Mellitus
The purpose of this study is to evaluate the safety and efficacy of YJP-14 capsules for the treatment of endothelial dysfunction in patients with diabetes mellitus.
- Trial name
- NCT01836172
- Testing
- YJP-14
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Han Wha Pharma Co., Ltd.
T2DM (Type 2 Diabetes Mellitus)
A Study of SYH2069 Injection in Participants With T2DM Not Controlled With Diet/Exercise Alone or Metformin
This study is a multicenter, randomized, double-blind, placebo and active-controlled, dose-finding phase 2 study aimed to evaluate the efficacy, safety, pharmacokinetics (PK) and immunogenicity of SYH2069 Injection in…
- Trial name
- NCT07796477
- Testing
- SYH2069 Injection (group 1), SYH2069 Injection (group 2), SYH2069 Injection (group 3)
- Where
- China
- Volunteers
- 240 people
- Sponsor
- CSPC Ouyi Pharmaceutical Co., Ltd.
Diabetes Mellitus
Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus
The purpose of this study is to determine the efficacy and safety of SYR-472, once daily (QD), in subjects with type 2 diabetes mellitus who have not achieved glycemic control with diet and exercise, or by taking metformin.
- Trial name
- NCT00760344
- Testing
- SYR-472, Sitagliptin
- Where
- 112 sites in United States, Mexico
- Volunteers
- 386 people
- Sponsor
- Takeda
Wolfram Syndrome
Efficacy Study of Daily Administration of VPA in Patients Affected by Wolfram Syndrome
Open label, phase II study non randomized single group assignment of 20 evaluable patients 13 years and older, over 37,5 kg body-weight, with sensorineural hearing loss of at least 20 dB at 8 kHz in high frequency average (HFA)…
- Trial name
- AUDIOWOLF (NCT04940572)
- Testing
- Depakine
- Where
- 2 sites in France, Spain
- Volunteers
- 23 people
- Sponsor
- Centre d'Etude des Cellules Souches
Xerostomia, Diabetes Mellitus
Photobiomodulation In Treatment Of Xerostomia In Type Ii Diabetic Patients
Xerostomia is a major oral health problem that if not recognized and treated can have a significant effect on a patient's quality of life. It leads to difficulties with speech, swallowing and taste alteration.
- Trial name
- NCT06703372
- Testing
- Diode Laser 980 nm, 0.2W
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Hams Hamed Abdelrahman