Clinical trials: Diabetes Mellitus II
Recurrence, Diabetic Foot
Prevention and Early Detection of Ulcer Recurrence in Patients With Type II Diabetes Mellitus
The goal of this clinical trial is to to evaluate the effectiveness of prevention strategies of recurrence in DFU's. It will also to detect the risk level of recurrence.
- Conditions
- Recurrence, Diabetic Foot, Thermography, Quality of Life
- Trial name
- NCT06434922
- Testing
- Prevention Strategies, Standard Strategiies
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Institute Technology and Health Muhammadiyah West Kalimantan
Type II Diabetes Mellitus, Obesity
Metabolomics of Roux-en-Y Gastric Bypass (RYGB) With Gastrostomy
This study is an investigation of the "metabolomics of RYGB with gastrostomy."
- Trial name
- NCT00887302
- Testing
- Gastric Band, Gastric Sleeve, Gastrostomy Tube
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- East Carolina University
Diabetic Nephropathy, Persistent Proteinuria With Type II Diabetes
Renal Denervation in Diabetic Nephropathy
The DERENEDIAB study is a proof-of-concept, multi-center, prospective, open, randomized, controlled study of the effectiveness of renal denervation in addition to standardized medical treatment compared to medical treatment alone…
- Trial name
- DERENEDIAB (NCT01588795)
- Testing
- Percutaneous renal denervation and TMNS, Standardized antiproteinuric medication regimen includes an angiotensin receptor blocker , a diuretic , 25OH vitamin D3 and a statin
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetic Neuropathies
Effect of Educational Booklet for Foot-related Exercises for Prevention and Treatment in People With Diabetic Neuropathy
The main objective of this trial is to investigate the effect of an educational booklet foot-related exercise in diabetic neuropathy status, functional outcomes and gait biomechanics in people with diabetic neuropathy.
- Trial name
- FOCA-II (NCT04008745)
- Testing
- Educational and home-based physical therapy by foot-related exercises
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
Polymorphism, mRNA Expression
Polymorphids an mRNA Expression in Obese Genes
Fat tissue from omenta, thigh and abdomen taken under anesthesia on subjects undergoing laparoscopic surgery, cholecystectomy, reflux surgery or gastric by-pass (GBP).
- Trial name
- NCT01708083
- Where
- 2 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
Type II Diabetes, Primary Health Care
INTEGRATE-D: A Pilot Test to Support Integration of Medical and Psychosocial Care for People With Type II Diabetes
In 2016, the American Diabetes Association (ADA) published its first-ever recommendations for integrating medical and psychosocial care for patients with Type II Diabetes Mellitus (DMII) and common mental and behavioral health…
- Conditions
- Type II Diabetes, Primary Health Care, Behavioral Health
- Trial name
- NCT04461405
- Testing
- INTEGRATE-D
- Where
- United States
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Diabetes
Reproducibility and Method Comparison Studies of the Quo-Test™ A1C System and the Quo-Lab A1C Test and CLIA Waiver Study of the Quo-Test™ A1C System
The Quo-Test A1C Analyzer and Reagent Test System (Quo-Test A1C System) are intended for the in-vitro quantitative determination of glycated hemoglobin in whole blood samples obtained from fingerstick or venous samples for…
- Trial name
- NCT01829061
- Where
- 3 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Quotient Diagnostics Limited
Type 2 Diabetes, Magnesium Disorder
Effect of Oral Magnesium Supplementation on Type II Diabetes Mellitus Guided by Serum Ionized Magnesium Level
Studies have shown that type 2 diabetic patients (T2DM) may have low serum magnesium levels leading to poor control and outcome of the disease. Supplementation with Mg might improve overall diabetic control and disease outcome.
- Trial name
- NCT05774015
- Testing
- Magnesium Oxide tablet 500 mg
- Where
- Oman
- Volunteers
- 247 people
- Sponsor
- Sultan Qaboos University
Diabetic Foot Ulcer
Prevention of Infection Using a Topical Gentamicin-Collagen Sponge in Diabetic Patients With An Uninfected Foot Ulcer
The purpose of this study is to determine the safety and efficacy of the topical gentamicin collagen sponge (gentamicin sponge) combined with standard of care (daily wound care, off-loading, diabetic control and debridement by a…
- Trial name
- NCT00658957
- Testing
- gentamicin-collagen sponge
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Innocoll
Metabolic Surgery
Could Single-anastomosis Gastric Bypass Be a Curative Treatment for Type II Diabetes?
Single- Anastomosis gastric bypass (SAGB) is a potentially curative line of treatment for type II diabetes mellitus (T2DM) patients with BMI 25-30 kg/m2. Accordingly, SAGB could be integrated into T2DM treatment algorithm
- Trial name
- NCT03412253
- Testing
- Single-Anastomosis Gastric Bypass surgery (SAGB).
- Volunteers
- 17 people
- Sponsor
- Ain Shams University
T2 Diabetes and Fatty Liver Disease (Non-alcoholic Origin)
A Study to Investigate Effects of Omega-3 Carboxylic Acids and Dapagliflozin on Liver Fat Content in Diabetic Patients
This study is a double-blind randomized, placebo-controlled, parallel-group, 12 week study performed in up to 5 centres in Sweden to assess the effect of Omega-3 carboxylic acids and dapagliflozin on liver fat in patients with…
- Trial name
- EFFECTII (NCT02279407)
- Testing
- Omega-3 carboxylic acids, Dapagliflozin
- Where
- 5 sites in Sweden
- Volunteers
- 223 people
- Sponsor
- AstraZeneca
Type II Diabetes
Clinical Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LEZ763
This study is a three part study to assess the safety and efficacy of LEZ763 on normal healthy volunteers and patients with Type 2 Diabetes.
- Trial name
- NCT01619332
- Testing
- Sitagliptin, LEZ763
- Where
- 6 sites in United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Diabetic Retinopathy
Intravitreal Triamcinolone Acetonide for Treatment of Refractory Diffuse Diabetic Macular Edema
Phase I/II study with intravitreal triamcinolone acetonide microspheres(RETAAC)for treatment of diffuse diabetic macular edema unresponsive to laser photocoagulation.
- Trial name
- NCT00407849
- Testing
- triamcinolone acetonide
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Federal University of São Paulo
Chronic Kidney Disease, Hypertension
Patiromer in the Treatment of Hyperkalemia in Patients With Hypertension and Diabetic Nephropathy (AMETHYST-DN)
This study determined the optimal starting dose of patiromer in treating hyperkalemia in participants with hypertension and diabetic nephropathy who were already receiving ACEI and/or ARB drugs, with or without spironolactone.
- Conditions
- Chronic Kidney Disease, Hypertension, Hyperkalemia
- Trial name
- AMETHYST-DN (NCT01371747)
- Testing
- patiromer, losartan, spironolactone
- Where
- 43 sites in Croatia, Georgia and 3 more
- Volunteers
- 324 people
- Sponsor
- Relypsa, Inc.
Diabetes Mellitus, Type 2
A Comparative Study of the Effect of Ayurvedic Drugs and Metformin in the Management of Diabetes Mellitus (Type II)
Present study entitled "A Comparative Study of the Effect of "Chhinnavahni Kashaya Vati" along with "Agnimantha Kwatha" \& Metformin in the management of Madhumeha w.s.r.
- Trial name
- NCT05451147
- Testing
- Chhinnavahni Kashaya Vati along with Agnimantha Kwatha, Metformin Hydrochloride
- Where
- India
- Volunteers
- 48 people
- Sponsor
- A & U Tibbia College Karol Bagh
Diabetes Mellitus, Type II
Episodic to Real-Time Care in Diabetes Self-Management
This study will use mobile health technologies to provide everyday data to help patients and their care providers better understand illness dynamics and develop adaptive approaches to improve health outcomes in diabetes.
- Trial name
- NCT03012074
- Testing
- Type 2 Diabetes Self-Management
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Myocardial Infarction, Diabetes Mellitus, Type 2
Aerobic Training in Post-MI Patients With DPN
Cardiac rehabilitation (CR) is categorized by the American College of Cardiology "class IA recommendation" in the management of patients with cardiovascular disease (CVD) including post-myocardial infarction (MI) patients, who…
- Conditions
- Myocardial Infarction, Diabetes Mellitus, Type 2, Diabetic Peripheral Neuropathy
- Trial name
- NCT03913793
- Testing
- Exercise based-cardiac rehabilitation (EB-CR) program
- Volunteers
- 37 people
- Sponsor
- Yousra Hisham Abdel Fattah
Type2 Diabetes, Self Efficacy
The Effect of Tele-Nursing Based Motivational Interviewing in Individuals With Type 2 Diabetes:RCT
This study carried out to examine the effect of tele-nursing based motivational interviewing on diabetes self-efficacy, diabetes self-management and metabolic control parameters (Body mass index, waist circumference…
- Conditions
- Type2 Diabetes, Self Efficacy, Self Management, Tele-nursing
- Trial name
- NCT05628259
- Testing
- Tele-Nursing based Motivational Interviewing
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Pamukkale University
Type 2 Diabetes Mellitus
Effects of Mixed Herbs on Blood Glucose and Lipid Profile in T2DM Patients
The aim of this study was to evaluate the effects of mixed herbs as ad-on therapy on blood sugar and lipid profile of patients with established T2DM.
- Trial name
- T2DM (NCT02159846)
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- International Islamic University Malaysia
Diabetes Mellitus
Safety Comparison of Pioglitazone and Glyburide in Type 2 Diabetes Subjects With Mild to Moderate Congestive Heart Failure
The purpose of this study is to compare the safety of Pioglitazone, once daily (QD), to Glyburide in Type 2 Diabetes Subjects with Mild to Moderate Congestive Heart Failure
- Trial name
- NCT00521820
- Testing
- Pioglitazone, Glyburide
- Volunteers
- 518 people
- Sponsor
- Takeda