Clinical trials: Diabetes Mellitus II
Type II Diabetes Mellitus
Mobile Health Technology as an Intervention for Diabetes Self-Management
This purpose of this is study is to evaluate the effectiveness of an interactive mobile health information service, Care4Life, in supporting patient self-management of Type II Diabetes Mellitus.
- Trial name
- Care4Life (NCT01546844)
- Testing
- Participation in Care4Life
- Where
- 30 sites in United States
- Volunteers
- 500 people
- Sponsor
- HealthInsight
Diabete Type 2
Assessing Heart and Brain Metabolism in Type II Diabetes Mellitus Patients Using Carbon-13 MRI
There has been a notable increase in the number of Canadians living with type II diabetes. People with this type of diabetes often have high levels of a substance called lactate in their blood, which might be linked to problems…
- Trial name
- NCT07820722
- Testing
- C13 Hyperpolarized pyruvate injection
- Volunteers
- 32 people
- Sponsor
- Sunnybrook Health Sciences Centre
Diabetic Nephropathy
Evaluating the Renoprotective Effect of Milk Thistle Extract on Patients With Type II Diabetic Nephropathy
There is considerable evidence that increased blood glucose results in the generation of reactive oxygen species, ultimately leading to increased oxidative stress in a variety of tissues.
- Trial name
- NCT01003236
- Testing
- Milk Thistle extract
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Shiraz University of Medical Sciences
Diabetes Mellitus Type II
Predictors of Future Type 2 Diabetes Mellitus in Circassians Minority in Israel
The aim The aim of the present study is: 1. The metabolic risk factors that can predict diabetes after 10 years in a Circassians population-based sample of people who were aged 35 years or older and living in Israel. 2.
- Trial name
- NCT01311401
- Testing
- NONE intervention
- Where
- Israel
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Periodontitis, Type2 Diabetes
Effect of Aspirin Vs Omega 3 Fatty Acid After Scaling and Root Planing in Type II Diabetic Patients With Chronic Periodontitis
The main aim and objective of this study is to compare the effectiveness of low dose aspirin vs omega 3 fatty acids as adjuvants to non-surgical periodontal therapy and also to evaluate the levels of pentraxin 3 and glycosylated…
- Trial name
- EAOFASRPDMCP (NCT03599401)
- Testing
- Scaling and root planing
- Where
- India
- Volunteers
- 42 people
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Diabetes Mellitus, Vitamin D Deficiency
Does Vitamin D Improve Glycemic Control in Type II DM?
Vitamin D status has been negatively associated with the presence of type II DM and glycemic control. However, a cause-effect relationship between vitamin D deficiency and glycemic control has not been established.
- Trial name
- NCT01170442
- Testing
- vitamin D3 2000 IU, vitamin D3 5000 IU
- Where
- Saudi Arabia
- Volunteers
- 25 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Diabetes Type 2, Impaired Glucose Tolerance
ARA290 in T2D (Effects of ARA 290, an Erythropoietin Analogue) in Prediabetes and Type 2 Diabetes)
The purpose of this study is to determine whether a non-hematopoietic erythropoietin analogue, ARA 290, exerts beneficial effects on blood glucose levels and insulin secretion in persons with prediabetes (impaired glucose…
- Conditions
- Diabetes Type 2, Impaired Glucose Tolerance, Impaired Fasting Glucose
- Trial name
- NCT01933529
- Testing
- ARA 290
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Claes-Göran Östenson
Type II Diabetes
Measuring the Preferences of Patients With Type II Diabetes Using Best-worst Scaling and Discrete Choice Experiment
In 2012, the FDA Center for Devices and Radiological Health (CDRH) issued guidance to clarify the principal benefit-risk factors FDA considers during the reviews for premarket approval applications and de novo classification…
- Trial name
- NCT02637622
- Testing
- Best-Worst Scaling (Case 2), Discrete Choice Experiment
- Where
- United States
- Volunteers
- 1,103 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Neuropathic Pain, Quality of Life
Neuropathic Pain and Type II Diabetic Patients
Diabetes Mellitus (DM) is a common metabolic disease characterized by hyperglycemia resulting from insufficiency, deficiency or absence of the insulin hormone.
- Conditions
- Neuropathic Pain, Quality of Life, Diabetic Neuropathies
- Trial name
- NCT06798181
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Type II Diabetes Mellitus, Mixed Dyslipidemia
Diabetes and Combined Lipid Therapy Regimen (DIACOR) Study
The primary study hypothesis of this study is to determine whether there is a greater percentage of patients achieving a triglyceride level of <200 mg/dL with the combination of simvastatin 20 mg and fenofibrate 160mg than with…
- Trial name
- NCT00309712
- Testing
- fenofibrate 160 mg and simvastatin 20 mg
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Intermountain Health Care, Inc.
Oxidative Stress
Vitamin E or Lipoic Acid on Serum Oxyphytosterol Concentrations
Background of the study: We now know that plant sterols can oxidize, which results in the formation of oxyphytosterols. Animal studies have suggested that oxyphytosterols are atherogenic components, however this relation has not…
- Trial name
- NCT01984567
- Testing
- Vitamin E, Lipoic acid, Control
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Maastricht University Medical Center
Diabetes Mellitus
Observational Study to Assess Glycosylated Hemoglobin Changes After 6 Months of Treatment With Pioglitazone.
The purpose of this study is to asses changes in glycosylated hemoglobin, fasting blood lipids and genetic polymorphism's in peroxisomal proliferator activated receptors--gamma receptor after 6 months of pioglitazone, once daily…
- Trial name
- NCT00449553
- Testing
- Pioglitazone and sulphonylurea, Pioglitazone and metformin
- Where
- 4 sites in Denmark, Iceland and 2 more
- Volunteers
- 326 people
- Sponsor
- Takeda
Diabetes Mellitus
Efficacy and Safety Study of Alogliptin and Insulin in the Treatment of Type 2 Diabetes.
The purpose of this study is to determine the efficacy and safety of alogliptin, once daily (QD), taken in combination with insulin for the treatment of Type 2 Diabetes.
- Trial name
- NCT00286429
- Testing
- Alogliptin and insulin, Insulin
- Where
- 60 sites in United States, Argentina and 14 more
- Volunteers
- 390 people
- Sponsor
- Takeda
Diabetes Mellitus, Type 2
Effect of Exercise on Cardiometabolic Risk Factors in Type II Diabetic Patients
Background: Physical activity is known to modify some of the diabetes risk factors; however, solid evidence is still needed to precisely know the optimum form of training best fits the individual needs of type II diabetic (T2D)…
- Trial name
- NCT04759469
- Testing
- High-intensity interval training, Moderate intensity interval training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Type 2 Diabetes
Can Enhanced Glycemic Control in Type II Diabetics Improve Myocardial Protection During Coronary Artery Bypass Grafting?
The investigators have previously demonstrated that the administration of insulin in the form of an infusion with additional sugar and potassium may improve cardiovascular performance and reduce biochemical evidence of heart…
- Trial name
- GUIDE (NCT00899483)
- Testing
- Glucose potassium insulin solution
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham
Type II Diabetes
Type II Diabetes Influence on Left Ventricular Remodeling and Outcomes in Patients Undergoing Aortic Valve Replacement Surgery.
This project focuses on the physiopathology of left ventricular remodeling associated with type II diabetes in patients with aortic valve stenosis referred for surgical aortic valve replacement.
- Trial name
- DIAPASON (NCT01862237)
- Testing
- Intervention
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Type 2 Diabetes Mellitus, Overweight
The TANTALUS® II System for the Treatment of Type 2 Diabetes: A Randomized Study
The main purpose of this research study is to investigate whether the TANTALUS II System is effective in improving glycemic (blood sugar) control in subjects who have type 2 diabetes (high blood sugar) and are overweight.
- Trial name
- NCT00547482
- Testing
- TANTALUS(TM) System
- Where
- 10 sites in United States
- Volunteers
- 300 people
- Sponsor
- MetaCure (USA), Inc.
Diabetes Mellitus, Type II
Measuring Patient Engagement in Diabetes Care
We will develop a new measure of patient engagement/activation specific to the context of diabetes self-care
- Trial name
- NCT02988427
- Sponsor
- Northwestern University
Erectile Dysfunction
Efficacy and Safety of Lodenafil Carbonate in the Treatment of Erectile Dysfunction in Patients With Diabetes.
Sixty diabetes men with erectile dysfunction from mild to severe who agree to participate is going to have medical care approximately for 16 weeks.
- Trial name
- NCT01180283
- Testing
- lodenafil carbonate
- Where
- 3 sites in Brazil
- Sponsor
- Cristália Produtos Químicos Farmacêuticos Ltda.
Diabetes Mellitus, Type 2, Obesity
Pharmacodynamic Study of the Effect of INCB013739 on Insulin Sensitivity in Obese, Type 2 Diabetic Subjects
Purpose: A 28-day US study in patients with type 2 diabetes mellitus to assess the safety and tolerability as well as the effects of treatment with an investigational drug.
- Trial name
- NCT00478322
- Testing
- INCB013739
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Incyte Corporation