Clinical trials: Diabetes Prevention
Diabetes Mellitus, Type 2, Metabolic Syndrome
A Patient-Centered Strategy for Improving Diabetes Prevention in Urban American Indians
The goal of the proposed research is to identify effective patient-centered strategies to prevent diabetes in high-risk populations in real world settings.
- Conditions
- Diabetes Mellitus, Type 2, Metabolic Syndrome, Insulin Resistance
- Trial name
- NCT02266576
- Testing
- Standard DPP, Enhanced DPP
- Where
- 2 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cardiovascular Diseases, Diabetes
The Flamenco (Fitness League Against MENopause COsts) Project
Spain is the second country in the world that consume more drugs. The average drug expenditure per capita in Andalucía during 2011 was 219.2 €. This drug spending increases during the perimenopausal period.
- Conditions
- Cardiovascular Diseases, Diabetes, Dyslipidemias, Metabolic Syndrome
- Trial name
- FLAMENCO (NCT02358109)
- Testing
- exercise
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Obesity Prevention, Diabetes Prevention
Types of Starch and Their Effect on Blood Glucose, Appetite and Food Intake
The investigators hypothesize that different types of starch vary in their effects on appetite, blood sugar and food intake. In this study, subjects consumed five soups containing 50 g of whole grain, high amylose corn, regular…
- Trial name
- NCT00988689
- Testing
- Dietary Intervention
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Gestational Diabetes
Prevention of Gestational Diabetes
Pregnancy is a vulnerable period for both a mother and her developing child. The investigator hypothesizes that diet-induced glucose excursions in the pregnant mother are a key contributor to unfavourable brain development and…
- Trial name
- NuPreGDM (NCT04028089)
- Testing
- Diet Modification Group, Regular Diet Group
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Diabetic Foot Ulcer
Improving DFU Outcomes: Early Detection of Foot Ulcers Using Novel Technology
The investigator team will study the adherence of the participant cohort to a non significant risk device over a six month period.
- Trial name
- DFUMAT (NCT05968924)
- Testing
- Podimetrics SmartMat
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Health Promotion, Cardiovascular Disease
Effectiveness and Cost-effectiveness of the Check Your Health Preventive Programme
Check your health is a prevention intervention designed to create awareness and action on health condition with focus at physical activity at a population-level to 30-49 years of age.
- Conditions
- Health Promotion, Cardiovascular Disease, Physical Inactivity, Selfreported Quality of Health
- Trial name
- NCT02028195
- Testing
- Health check
- Where
- Denmark
- Volunteers
- 11,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Diabetes Mellitus, Type 2, Obesity
Lifestyle Modification for Type 2 Diabetes Prevention in Overweight Youth
The number of youth with Type 2 diabetes (T2D) is rising in the population, which is a concerning public health trend. There has been little research testing ways to prevent the development of this disease in children who are at…
- Trial name
- NCT01610219
- Testing
- Lifestyle Modification for Type 2 Diabetes Prevention, Nutrition and Physical Activity
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Gestational Diabetes Mellitus in Pregnancy
Lifestyle Intervention IN Gestational Diabetes (LIVING)
Investigators have taken the learning from various programs to develop a new lifestyle program (LIVING) that has a high probability of being feasible, acceptable and cost-effective in the South Asian context for women with prior…
- Trial name
- LIVING (NCT03305939)
- Testing
- Life style Intervention
- Where
- 20 sites in Bangladesh, India and 1 more
- Volunteers
- 1,612 people, healthy volunteers welcome
- Sponsor
- The George Institute
Diabetes Prevention
The Reach and Effectiveness of Technology-enhanced Diabetes Prevention Programs
The aim of this project is to evaluate the reach, effectiveness, and costs of two patient-centered, theory-based, technology-enhanced diabetes prevention programs to initiate and sustain weight loss among pre-diabetic adults…
- Trial name
- DiaBEAT-it (NCT02162901)
- Testing
- Choice-Class with IVR Calls, Random-Class with IVR calls, Random-Class only
- Where
- United States
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Pre Diabetes
Diabetes Prevention Program in Youth
The purpose of this study is to test the effectiveness of an out-of-school diabetes prevention program for youth (ages 7-15) with a family history of pre-diabetes or type 2 diabetes.
- Trial name
- NCT03042936
- Testing
- Insulin Superheroes Club Curriculum
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Diabetes
Sustainable Culturally Adapted Nutrition (SCAN) Program
The purpose of the study is to determine the impact of an enhanced, food incentive program [called the sustainable culturally adapted nutrition (SCAN) program], which is integrated with the Diabetes Prevention Program (DPP) and a…
- Trial name
- NCT07220057
- Testing
- Live instructional video sessions, Links to educational videos, Diabetes Prevention Program (DPP)
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Type 2 Diabetes
Computer Based Intervention for Type 2 Diabetes in Youth
Interactive multimedia programs have been demonstrated to produce substantial change in children's dietary behaviors. This SBIR-Phase 2 protocol will evaluate the two video game interventions designed to change diabetes related…
- Trial name
- NCT00570466
- Testing
- Video Games, Web and DVD knowledge
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 1 Diabetes
Beta Cell Function in (Pre)Type 1 Diabetes
Increased glycemic variability has been proposed as an independent predictor of hypoglycemia in diabetic patients. Likewise, episodes of dysglycemia have been found to be predictive of diabetes in antibodypositive nondiabetic…
- Trial name
- NCT01402037
- Testing
- Glucose, Continuous glucose monitoring
- Where
- 3 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Hypertension, Dyslipidemias
Addressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US
This study has 3 aims. Aim 1: Identify social determinants of cardiometabolic health and determine facilitators and modifiable barriers in achieving treatment goals.
- Conditions
- Hypertension, Dyslipidemias, Type 2 Diabetes, HIV-1-infection
- Trial name
- NCT05129345
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Duke University
Diabetes, Alzheimer Disease
The Diabetes Prevention Program Outcomes Study AD/ADRD Project
The DPPOS AD/ADRD project will address the overarching question: What are the determinants and the nature of cognitive impairment among persons with pre-diabetes (PreD) and type 2 diabetes (T2D), who are a high-risk group for…
- Conditions
- Diabetes, Alzheimer Disease, Dementia, Vascular, Dementia
- Trial name
- DPPOS-4 (NCT05704309)
- Where
- 27 sites in United States
- Volunteers
- 1,976 people, healthy volunteers welcome
- Sponsor
- Marinella Temprosa
Type 1 Diabetes
Importance in Type 1 Diabetes Patients of an Optimized Control of Post-Prandial Glycaemia on Oxidant Stress Prevention
The aim of this study is to determine whether postprandial hyperglycaemia plays an important role in oxidative stress phenomena and influences their harmful effects on the arterial wall.
- Trial name
- ITOPOS (NCT00934336)
- Testing
- Therapeutic and preventive strategies
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
PreDiabetes
Lifestyle Modification Intervention in Pre-diabetic Subjects
The lifestyle intervention program focusing on healthy dietary habit and exercise effectively prevents progression to diabetes. Thus, the purpose of this study was to assess the effectiveness of lifestyle intervention program on…
- Trial name
- NCT03211182
- Testing
- lifestyle modification intervention
- Where
- 4 sites in Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Obesity, Insulin Resistance
Vitamin K to Slow Progression of Dyslipidemia and Diabetes Risk (Vita-K 'n' Kids Study II)
Animal studies have found that vitamin K-dependent proteins matrix Gla protein and osteocalcin beneficially influence lipid and glucose metabolism, respectively.
- Conditions
- Obesity, Insulin Resistance, Obesity in Diabetes, Nutritional and Metabolic Diseases
- Trial name
- NCT02959762
- Testing
- Low-Dose Vitamin K2 (menaquinone-7; 45-mcg/d), High-Dose Vitamin K2 (menaquinone-7; 90 mcg/d)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Augusta University
Foot Ulcer, Diabetic
Pressure Alternating Shoes
The project is designed to develop and test Pressure Alternating Shoes (PAS), which will periodically off-load certain regions of the foot in order to prevent foot ulcers.
- Trial name
- PAS (NCT06026813)
- Testing
- test pressure alternating shoes
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Diabetes, Weight Loss
Lifestyle Change to Prevent Diabetes Via African-American Churches
Fit Body and Soul is single-blinded, cluster- randomized trial of a faith-based adaptation of the GLB program compared with a health education intervention.
- Trial name
- NCT01730196
- Testing
- Fit Body and Soul, Wellness Education
- Where
- United States
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- Augusta University