Clinical trials: Diabetes Risk, active
Chronic Kidney Disease Stage 3 and 4, Diabetes
Prediction of Peripheral Neuropathy With Functional Testing
Diabetes and chronic kidney disease (CKD) are two distinct pathologies. The former is defined as an impairment in insulin production and/or utilization, while the latter refers to structural or functional abnormalities of the…
- Trial name
- PredictNP (NCT06933108)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Université catholique de l'Ouest
Sedentary Behavior, Affect
Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children
The overall objective of this in-lab randomized controlled trial is to test the efficacy of multi-day interruptions in sedentary behavior vs.
- Conditions
- Sedentary Behavior, Affect, Metabolic Disturbance, Anxiety
- Trial name
- NCT04469790
- Testing
- SIT+WALK, EX
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Obesity, Childhood, Diabetes Mellitus, Type 2
The QUebec Adipose and Lifestyle InvesTigation in Youth (QUALITY) Cohort
The QUebec Adipose and Lifestyle InvesTigation in Youth (QUALITY) Cohort study is a unique and comprehensive longitudinal study of 630 Caucasian children and their parents that was designed to investigate the natural history and…
- Conditions
- Obesity, Childhood, Diabetes Mellitus, Type 2, Cardiovascular Risk Factor, Pediatric ALL
- Trial name
- QUALITY (NCT03356262)
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Chronic Kidney Disease, Type 2 Diabetes Mellitus
An Observational Study, Called FINEXPLORER, to Learn More About How Well Finerenone Works in Adults in Spain With Chronic Kidney Disease (CKD) Linked to Type 2 Diabetes, by Looking at Changes in a CKD Risk Score
This is a prospective observational study in which data from people with chronic kidney disease (CKD) associated with type 2 diabetes (T2D) who will be receiving finerenone are collected and analyzed.
- Trial name
- FINEXPLORER (NCT07554469)
- Testing
- Finerenone (Kerendia, BAY94-8862)
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Bayer
Breast Cancer Risk, Cardiovascular Disease Risk
The RISC Registry--Risk Informed Screening Registry
Chronic diseases such as heart disease, cancer, and diabetes are the leading causes of death and disability in the United States. Six in ten adults have one chronic disease; 4 in 10 have two or more.
- Conditions
- Breast Cancer Risk, Cardiovascular Disease Risk, Cardiometabolic Risk, Diabetes
- Trial name
- RISC (NCT05848856)
- Testing
- Breast Cancer, Cardiometabolic, Cardiovascular Risk Screening and Follow up
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Precision Health Equity Initiative
Healthy Population
Italian Digital Primary Cardiovascular Prevention Study
The CV-PREVITAL study is a randomised clinical trial (RCT) controlled versus usual-care designed to compare the effectiveness of a mobile health (mHealth) intervention with that of usual care in reducing specific cardiovascular…
- Trial name
- CV-PREVITAL (NCT05339841)
- Testing
- Mobile health application
- Where
- 32 sites in Italy
- Volunteers
- 27,520 people, healthy volunteers welcome
- Sponsor
- Centro Cardiologico Monzino
Type 1 Diabetes
Effects of Sitagliptin in Relatives of T1D Patients
Type 1 Diabetes (T1D) is a chronic autoimmune disease, with a genetic background, resulting from the immune-mediated destruction of beta cells of the pancreas.
- Trial name
- SITA-one (NCT05219409)
- Testing
- Sitagliptin, Professional CGM
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Milan
Cardiovascular Diseases, Surgery
Pressure Recording Analytical Method Parameters and Their Relationship With Hypotension in Hypertensive Patients
Perioperative anesthesiologists can benefit from easily obtainable hemodynamic variables detecting or quantifying the lack of an adequate compensatory capacity of the cardiovascular system in order to optimize patient management…
- Conditions
- Cardiovascular Diseases, Surgery, Hypotension, Hypotension on Induction
- Trial name
- PRAM-in-HYPO (NCT05960604)
- Testing
- Passive leg raising
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 660 people
- Sponsor
- Recep Tayyip Erdogan University
Cardiovascular Abnormalities, Arterial Blood Pressure
Multicenter Study on Cardiovascular and Metabolic Complications in Patients With Biochemically Silent Pheochromocytomas and Paragangliomas
The aim of the study is to characterise the cardiovascular and metabolic complications pre- and post-surgery of patients with biochemically negative PPGL and to compare them with normal individuals and patients with secreting…
- Conditions
- Cardiovascular Abnormalities, Arterial Blood Pressure, Heart Rate, Congestive Heart Failure Chronic
- Trial name
- NCT07316075
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laikο General Hospital, Athens
Gestational Diabetes, Pregnancy, High Risk
Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes
This is a multicenter randomized clinical trial of 828 overweight and obese individuals with gestational diabetes designed to compare standard to intensive glycemic targets.
- Conditions
- Gestational Diabetes, Pregnancy, High Risk, Overweight and Obesity
- Trial name
- iGDM (NCT05124808)
- Testing
- Intensive glycemic targets, Standard glycemic targets
- Where
- 5 sites in United States
- Volunteers
- 828 people
- Sponsor
- Indiana University
Type 1 Diabetes Mellitus (T1DM), Healthy Control
Environmental Determinants of Type 1 Diabetes Risk
To analyze the environmental risk factors for type 1 diabetes in China.
- Conditions
- Type 1 Diabetes Mellitus (T1DM), Healthy Control, Relatives to/Carers of Patients
- Trial name
- NCT07835724
- Where
- China
- Volunteers
- 11,240 people, healthy volunteers welcome
- Sponsor
- Second Xiangya Hospital of Central South University
Autism Spectrum Disorder (ASD), Cardiometabolic Health Indicators
This Study Will Evaluate Cardiorespiratory and Muscular Fitness to Examine Associations With Anthropometric Characteristics and Other Indicators of Cardiometabolic Risk Among Patients With or Without Autism Spectrum Disorder
The goal of this observational study is to evaluate cardiorespiratory and muscular fitness in children with obesity, with and without autism spectrum disorder (ASD), and examine how fitness relates to body measurements, body…
- Conditions
- Autism Spectrum Disorder (ASD), Cardiometabolic Health Indicators, Cardiometabolic Risk Factors, Metabolic Syndrome
- Trial name
- ROACH (NCT07804680)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Virginia
Diabetes Mellitus, Pancreas Transplantation
The Norwegian Pancreas Transplantation (PTx) Study
Several studies have shown acceptable results after Pancreas Transplantation (PTx) by substituting ATG with basiliximab, which is considered to convey a considerably lower number of adverse events.
- Conditions
- Diabetes Mellitus, Pancreas Transplantation, Allograft Rejection, Surgical Complication Nec
- Trial name
- PTx (NCT01957696)
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Atherosclerotic Cardiovascular Disease (ASCVD), Chronic Kidney Disease (CKD)
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)
The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent the worsening of kidney function.
- Trial name
- NCT06383390
- Testing
- Retatrutide
- Where
- 742 sites in United States, Argentina and 25 more
- Volunteers
- 10,000 people
- Sponsor
- Eli Lilly and Company
Postoperative Delirium, Type 2 Diabetes
Association of Preoperative Hippocampal Glucose Metabolism With Postoperative Delirium in Older Diabetic Patients
Objective: To investigate the association between preoperative hippocampal glucose metabolism levels and the risk of postoperative delirium (POD) in elderly patients with type 2 diabetes (T2DM), and to provide a prospective…
- Trial name
- NCT07369466
- Volunteers
- 154 people
- Sponsor
- Chinese PLA General Hospital
Type 2 Diabetes
A Study to Identify the Risk of Non-alcoholic Fatty Liver Disease (NAFLD) in Patients With Type 2 Diabetes in Clinical Practice and to Evaluate the Clinical Usefulness of Dapagliflozin/Pioglitazone Combination Therapy
The purpose of this study is to identify the risk of non-alcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes in clinical practice and to evaluate the clinical usefulness of Dapagliflozin/Pioglitazone…
- Trial name
- NCT06649162
- Where
- 2 sites in South Korea
- Volunteers
- 10,000 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Type 1 Diabetes, Liver Steatoses
Prevalence and Risk Factors of Metabolic-Associated Hepatic Steatosis in Individuals Living With Type 1 Diabetes
The goal of this observational cross-sectional study is to assess the prevalence and stage of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), specifically liver steatosis and fibrosis in adults aged 18 and older…
- Conditions
- Type 1 Diabetes, Liver Steatoses, MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Liver Fibrosis
- Trial name
- STEA-DT1 (NCT07475962)
- Testing
- Adiposity and BMI Classification
- Volunteers
- 100 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Diet, Food and Nutrition, Accidental Falls
Occupational Therapy and Registered Dietitian Services to Reduce Fall Risk Among Home Delivered Meal Clients
The purpose of this study is to determine which of the following four service models is most effective for reducing fall risk among home-delivered meal clients: (1) meals alone, (2) meals + registered dietitian services, (3)…
- Conditions
- Diet, Food and Nutrition, Accidental Falls, Cardiovascular Diseases, Diabetes
- Trial name
- NCT06586970
- Testing
- Meals + RD services, Meals + OT services, Meals + RD + OT services
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Ohio State University
Type 1 Diabetes Mellitus, Stage 2 Type 1 Diabetes
Information, Follow-up and Early Diagnosis of Children at Risk for Type 1 Diabetes
The aim is to investigate whether screening for islet autoantibodies, regular follow-up, and increased knowledge in families about the progression of the disease in children at high genetic risk or with single or multiple islet…
- Conditions
- Type 1 Diabetes Mellitus, Stage 2 Type 1 Diabetes, Stage 1 Type 1 Diabetes, Stage 3 Type 1 Diabetes
- Trial name
- iT1D (NCT06676566)
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Lund University
Diabetes Mellitus, Diabetic Foot Ulcer (DFU)
Risk Perception Intervention for High-Risk Diabetic Foot
This study aims to evaluate the effect of health education based on information framing effects on foot ulcer risk perception in patients at high risk of diabetic foot.
- Conditions
- Diabetes Mellitus, Diabetic Foot Ulcer (DFU), Risk Perception, Peripheral Neuropathy With Type 2 Diabetes
- Trial name
- NCT07581262
- Testing
- Gain-Framed, Loss-Framed, Routine Care
- Volunteers
- 90 people
- Sponsor
- The Third Affiliated Hospital of Soochow University