Clinical trials: Diabetes in Adolescence
Disability, Intellectual, Disability Psychological
The Role of Family and Individual Factors in Going Through Adolescence - Perspective of a Healthy Child.
The goal of this observational study is to investigate the specificity of the growing up process in young people with disabled siblings.
- Conditions
- Disability, Intellectual, Disability Psychological, Disability, Developmental, Diabetes
- Trial name
- NCT06156124
- Testing
- Psychological tests and psychosocial questionnaires
- Where
- Poland
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Gdansk
Sedentary Behavior, Affect
Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children
The overall objective of this in-lab randomized controlled trial is to test the efficacy of multi-day interruptions in sedentary behavior vs.
- Conditions
- Sedentary Behavior, Affect, Metabolic Disturbance, Anxiety
- Trial name
- NCT04469790
- Testing
- SIT+WALK, EX
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Obesity, Childhood, Diabetes Mellitus, Type 2
The QUebec Adipose and Lifestyle InvesTigation in Youth (QUALITY) Cohort
The QUebec Adipose and Lifestyle InvesTigation in Youth (QUALITY) Cohort study is a unique and comprehensive longitudinal study of 630 Caucasian children and their parents that was designed to investigate the natural history and…
- Conditions
- Obesity, Childhood, Diabetes Mellitus, Type 2, Cardiovascular Risk Factor, Pediatric ALL
- Trial name
- QUALITY (NCT03356262)
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Type 1 Diabetes
Happy Bob App: A Preliminary Evaluation of Its Use in Youth With Diabetes
The goal of this clinical trial is to evaluate the impact of peer support via the Happy Bob phone app in youth with Type 1 Diabetes.
- Trial name
- NCT06412601
- Testing
- RPM, app
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Obesity, Type 2 Diabetes
Reducing Obesity and Type 2 Diabetes in High Risk Youth
Compare the effect of the HEALT[e]TEEN program and a HEALTH[e]TEEN plus coping skills training delivered to high school students on BMI, nutrition and physical activity behaviors, and self-efficacy over 6 months.
- Trial name
- HEALTH[e]TEEN (NCT01560676)
- Testing
- HEALTH[e]TEEN, HEALTH[e]TEEN + CST
- Where
- United States
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity, Insulin Resistance
Apelin Levels and G212A Polymorphism of Apelin Receptor (APJ)
The aim of this study is to investigate serum apelin levels as well as their possible association with G212A polymorphism of the apelin receptor in obese children and adolescents.
- Conditions
- Obesity, Insulin Resistance, Diabetes Mellitus Type 2
- Trial name
- NCT01121172
- Where
- Greece
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Type1 Diabetes
Effect of Dual-wave Insulin Bolus on Postprandial Glycaemia
A study was conducted in adolescents with type 1 diabetes (T1D) examining the effect of different bolus types on 6-h postprandial glucose levels after the consumption of 3 standard meals with varying composition.
- Trial name
- NCT03179280
- Testing
- insulin
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Type 1 Diabetes Mellitus
Exercise Training Intervention in Children With Type 1 Diabetes
Type 1 diabetes mellitus (T1DM) is associated with multiple co-morbidities, such as hypertension, dyslipidemia, coronary heart disease and osteoporosis. The foundation of these conditions lays in childhood.
- Trial name
- Diabex (NCT01220479)
- Testing
- Exercise training program
- Where
- Switzerland
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Preclinical Imaging Biomarkers of Alzheimer's Disease Neuropathology in Young Adults With Youth-onset Diabetes: a Proof-of-concept Study
The goal of the study is to characterize preclinical Alzheimer's Disease and related dementias (AD/ADRD) neuropathology in a selected group of young adults with youth-onset diabetes, and an age-similar group of young adults…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetes, Youth Onset
- Trial name
- NCT05350514
- Testing
- PI-2620 tracer
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
PreDiabetes, Overweight
Night Owl Metabolism
The proposed study uses a novel and rigorous randomized cross-over study design in youth (18-23y) with late and non-late chronotype (n=35 per group) to assess the glycemic effect of "aligning" an oral glucose tolerance test…
- Conditions
- PreDiabetes, Overweight, Impaired Glucose Tolerance
- Trial name
- NCT06507722
- Testing
- Timing of OGTT, Timing of Standardized Meal
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obesity and Type 2 Diabetes
Circuit Training and Motivational Interviewing to Reduce Type 2 Diabetes in Youth
The overall goal of this project is to examine the physiological and metabolic effects of a 16-week circuit-training (strength training + aerobic activities) program, with and without a behavioral component utilizing motivational…
- Trial name
- NCT00693511
- Testing
- Circuit Training, Circuit training + motivational interviewing
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Diseases in Adolescence, Cardio Vascular Disease
Lifestyle Practices With Chronic Diseases Among Different Professionals
A qualitative study conducted in 2018 Exploring socio-cultural factors impacting adherence to type 2 diabetes therapy in rural Sargodha featured respondents who were primarily doctors, patients, and.
- Conditions
- Chronic Diseases in Adolescence, Cardio Vascular Disease, Diabetes Type 2
- Trial name
- NCT05865717
- Testing
- Quantitative sampling, Qualitative interviews
- Where
- Pakistan
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Health Services Academy, Islamabad, Pakistan
Diabetes in Adolescence, Type 2 Diabetes
Pilot-Testing Strategies to Improve Outcomes for Youth With Type 2 Diabetes by Addressing Health-Related Social Needs
The goal of this clinical trial is to pilot test different strategies to address health related social needs (HRSN) experienced by adolescent and young adult patients with type 2 diabetes and their families.
- Conditions
- Diabetes in Adolescence, Type 2 Diabetes, Social Needs
- Trial name
- ONWARD (NCT07216118)
- Testing
- Tailored Resources, Universal Empowerment, Text Messages
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Diabetes Mellitus, Type 2, Obesity
Lifestyle Modification for Type 2 Diabetes Prevention in Overweight Youth
The number of youth with Type 2 diabetes (T2D) is rising in the population, which is a concerning public health trend. There has been little research testing ways to prevent the development of this disease in children who are at…
- Trial name
- NCT01610219
- Testing
- Lifestyle Modification for Type 2 Diabetes Prevention, Nutrition and Physical Activity
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Type 1 Diabetes, T1D
DASH-Obesity: Explainable AI for Family-Centric Personalized Weight Control in Adolescents and Young Adults With Obesity and Chronic Conditions
This prospective single-arm feasibility study evaluates the Adhera Caring Digital Program for Obesity (ACDP-O), a family-centered digital health intervention designed to support adolescents and young adults with…
- Conditions
- Type 1 Diabetes, T1D, Obesity & Overweight, Obesity Type 2 Diabetes Mellitus
- Trial name
- DASH-Obesity (NCT07638345)
- Testing
- Adhera Caring Digital Program-Obesity (ACDP-O)
- Where
- Spain
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Adhera Health, Inc.
Pre Diabetes
Diabetes Prevention Program in Youth
The purpose of this study is to test the effectiveness of an out-of-school diabetes prevention program for youth (ages 7-15) with a family history of pre-diabetes or type 2 diabetes.
- Trial name
- NCT03042936
- Testing
- Insulin Superheroes Club Curriculum
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Type 2 Diabetes
Computer Based Intervention for Type 2 Diabetes in Youth
Interactive multimedia programs have been demonstrated to produce substantial change in children's dietary behaviors. This SBIR-Phase 2 protocol will evaluate the two video game interventions designed to change diabetes related…
- Trial name
- NCT00570466
- Testing
- Video Games, Web and DVD knowledge
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity, Insulin Resistance
Vitamin K to Slow Progression of Dyslipidemia and Diabetes Risk (Vita-K 'n' Kids Study II)
Animal studies have found that vitamin K-dependent proteins matrix Gla protein and osteocalcin beneficially influence lipid and glucose metabolism, respectively.
- Conditions
- Obesity, Insulin Resistance, Obesity in Diabetes, Nutritional and Metabolic Diseases
- Trial name
- NCT02959762
- Testing
- Low-Dose Vitamin K2 (menaquinone-7; 45-mcg/d), High-Dose Vitamin K2 (menaquinone-7; 90 mcg/d)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Augusta University
Obesity, Type 2 Diabetes
Activity and Metformin Intervention in Obese Adolescents
The purpose of this study is to assess the sustainability of a two-year intervention aimed at improving body mass index (BMI) and metabolic and vascular health in obese youth.
- Trial name
- REACH (NCT00934570)
- Testing
- Metformin and standard exercise, Metformin Intensive exercise, Intensive exercise
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Type 2 Diabetes Mellitus, Adolescent Obesity
A Study of the Effects of Exercise Intensity on Insulin Sensitivity in Overweight Youth
Background: The investigators know that exercise helps children develop strong bones and muscles and generally stay healthy. What is unclear however, is how much exercise a child needs to lower their risk of developing type 2…
- Trial name
- POWER (NCT00755547)
- Testing
- Aerobic Exercise Training
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manitoba