Clinical trials: Diagnostic
Adolescent Idiopathic Scoliosis
Identification of Circulating microRNAs in Adolescent Idiopathic Scoliosis
The aim of the present study is to evaluate the expression of a large panel of microRNAs, already known and validated in other ortopedic pathologies and bone metabolism, in the plasma of Adolescent Idiopathic Scoliosis (AIS)…
- Trial name
- IMIRSA (NCT04746586)
- Testing
- Circulating MiRNA indentification
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Healthy
Phase I Clinical Human Tolerability Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10
In the tests, small sample of clinical study about Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10 ( Recombination EC Allergen） healthy adults was carried out.
- Trial name
- NCT01999231
- Testing
- ESAT6-CFP10
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Autism Spectrum Disorder, Other Neurodevelopmental Disorder
Early Assessment of Autism Through Smart Tablet Gameplay
The primary aim of this study is to compare the diagnostic accuracy of an iPad application (Play.Care assessment) with the current clinical "gold standard" diagnosis for diagnosis of Autism Spectrum Disorder (ASD) in children.
- Trial name
- NCT03438994
- Testing
- Play.Care
- Where
- 2 sites in Sweden, United Kingdom
- Volunteers
- 779 people, healthy volunteers welcome
- Sponsor
- University of Strathclyde
Parkinson Disease
Use of BART Coupled With EEG in the Early Diagnosis of Behavioral Disorders in Parkinson's Disease
The Balloon Analogue Risk Task [BART] is an experimental task modelizing risky behaviors. In Parkinson disease, the correlation between BART and modifications of cerebral activity in ventral striatum has been shown.
- Trial name
- COMPARE (NCT05640986)
- Testing
- BART-EEG at V1 + V2, BART-EEG at V1 only
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
To Investigate the Inflammasome Response of Inflammatory and Resting Macrophage, To Compare the Difference of Inflammasome Response of Inflammatory Macrophage
The Role of Inflammasome in Inflammatory Macrophage in Mycobacterium Avium Complex-lung Disease and Mycobacterium Abscessus-lung Disease
1. To investigate the inflammasome response of inflammatory and resting macrophage derived from healthy human participants by stimulation using MAC or MAB bacilli. 2.
- Conditions
- To Investigate the Inflammasome Response of Inflammatory and Resting Macrophage, To Compare the Difference of Inflammasome Response of Inflammatory Macrophage, To Study the Diagnostic Aid From Immunological Markers in Inflammasome Response
- Trial name
- NCT02005094
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Chronic Rhinosinusitis (Diagnosis)
Silver Nanoparticle Investigation for Treating Chronic Sinusitis
Chronic rhinosinusitis is a highly prevalent disease resulting in high economic burden. Effective therapeutic options are needed. Rhinosinusitis-related biofilms are a likely contributor to recalcitrant disease.
- Trial name
- SNITCH (NCT03243201)
- Testing
- Colloidal silver nanoparticles, Purified Water
- Volunteers
- healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
HIV, Hepatitis C
Behavioral Science Aspects of Rapid Test Acceptance
The relevance of this research to public health is to make it possible to test for hepatitis C and syphilis at point of care so that people will receive their results immediately instead of requiring people to wait for at least a…
- Conditions
- HIV, Hepatitis C, Hepatitis B, Syphilis
- Trial name
- BSARTA (NCT01317784)
- Testing
- Rapid tests for HIV, HCV, HBV, and syphilis, HIV/HCV, HIV/syphilis
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- California State University, Long Beach
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Prospective Study on Diabetes Mellitus and Its Complications in Newly Diagnosed Adult Patients
The aim of the prospective observational GDC-Study in patients with newly diagnosed diabetes mellitus aged 18-69 years at inclusion into the study is to characterize in detail the clinical, metabolical and immunological phenotype…
- Trial name
- GDC (NCT01055093)
- Where
- Germany
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
COVID-19
Bioaerosol Sampling Device (BSD) Clinical Study
The goal of this clinical trial is to learn about the bioaerosol sampling device (BSD) and how it can sample patient bioaerosols (breath) and patient's nares for the detection of COVID-19 viral particles in patients seeking to be…
- Trial name
- NCT06047067
- Where
- 6 sites in United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Cantor BioConnect, Inc.
Toxoplasmosis, Toxoplasma Infections
Diagnosis of Toxoplasma Gondii Infection by Exploration of Cellular Immunity (TOXCELL)
Toxoplasmosis is a parasitic disease caused by Toxoplasma gondii and transmitted to humans through the consumption of raw or undercooked infected meat and / or by poorly washed vegetables.
- Conditions
- Toxoplasmosis, Toxoplasma Infections, Toxoplasmosis, Congenital, Toxoplasmosis Recurrent
- Trial name
- TOXCELL (NCT04825600)
- Testing
- anti-Toxoplasma gondii IgG and IgM dosage, cellular test
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Acute Coronary Syndrome
Potential Diagnostic and Prognostic Value of microRNAs for the Patients of Acute Coronary Syndrome
The purpose of this study is to evaluate the potential diagnostic and prognosis value of circulating microRNAs compared with cTnI for suspected ACS patients at the emergency department (ED) and intensive care unit (ICU).
- Trial name
- NCT02755207
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Prostatic Neoplasms, Metastases
68Ga-PSMA PET in the Prostate Cancer
Efficacy of 68Ga PSMA PET / CT in the diagnosis of lymph node metastasis in patients with prostate cancer: a single center prospective randomized controlled trial.
- Conditions
- Prostatic Neoplasms, Metastases, PSMA-PET
- Trial name
- NCT04967001
- Testing
- PSMA PET
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Pathology
A Trial on the Effect of Simulation-based Diagnostic Abdominal Ultrasound Training
The investigators hypothesise that simulation-based training will have initial educational benefits and in coherence with the traditional apprenticeship model will heighten the educational end-level: That training on the…
- Trial name
- NCT02921867
- Testing
- Simulation-based training
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Short Stature
The Role of Igf-1 Generation Test in Diagnosis and Treatment of Short Stature
The purpose of the study is to evaluate the predictive value of IGF-1 generation test for growth velocity during GH treatment for 12 months.
- Trial name
- NCT01970800
- Testing
- Growth Hormone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Diabetes Mellitus, Type 2, Hypertension
Scaling Up NCD Interventions in South East Asia
The SUNI-SEA study is an intervention study that measures effectiveness and cost-effectiveness of prevention and early diagnosis of diabetes and cardiovascular diseases in communities and primary healthcare (PHC) facilities in…
- Conditions
- Diabetes Mellitus, Type 2, Hypertension, Cardiovascular Diseases
- Trial name
- SUNI-SEA (NCT05239572)
- Testing
- screening, prevention and counselling
- Where
- Vietnam
- Volunteers
- 16,850 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Femoroacetabular Impingement, Hip Developmental Dysplasia
Cross-sectional Study of Ultrasonic Diagnosis of Iliac Joint Capsule Muscle
In order to investigate the relationship between the iliac joint capsular muscle and the development of the hip joint, this study used ultrasound Doppler to measure the anatomical circumference of the iliac joint capsular muscle…
- Trial name
- NCT04968301
- Testing
- ultrasound Doppler
- Where
- China
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Surgical Site Infection, Zonulin
Zonulin Biomarker for Diagnosis of Hip and Knee Infections
Prior studies investigating the etiopathogenesis of surgical site infection (SSI) traditionally suggested three main ways for the infection to occur: local contamination occurring during the surgery, hematogenous translocation of…
- Trial name
- NCT04666519
- Testing
- Zonulin Biomarker
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Covid19, Androgen Receptor Gene Overexpression
COVID-19 In-vitro Diagnostic Test and Androgen Receptor Gene Expression
This research study will evaluate the association of Androgen Receptor (AR) gene expression and COVID-19 disease severity and mortality.
- Trial name
- NCT04530500
- Testing
- COVID-19 Androgen Sensitivity Test (CoVAST)
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Osteoarthitis, Osteoporosis
Evaluation of Musculoskeletal Aging and Related Disorders Via Advanced Clinical Imaging
Study Overview This clinical research focuses on the development and validation of a multimodal artificial intelligence (AI) platform designed for the automated diagnosis and precise staging of two major musculoskeletal…
- Trial name
- NCT07474571
- Testing
- No Interventions
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Tuberculosis, Pulmonary
Integrated Discovery and Development of Innovative TB Diagnostics
The long term goal of this project is to provide information critical to the development and use of a low-cost, point-of-care, rapid, simple, and highly accurate diagnostic tool that can help clinicians make a microbiological…
- Trial name
- (CETR) (NCT06624501)
- Testing
- Observational cohort study
- Volunteers
- 1,450 people, healthy volunteers welcome
- Sponsor
- Harvard University Faculty of Medicine
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