Clinical trials: Diagnostic Accuracy
Peripheral Arterial Disease (PAD), Ankle Brachial Index
Automated ABPI in Peripheral Arterial Disease a Pilot Study
The aim of this pilot study is to investigate the diagnostic accuracy of two automated ABPI devices across the spectrum of PAD (asymptomatic PAD, suspected symptomatic PAD [IC; including mild moderate and severe IC based on the…
- Conditions
- Peripheral Arterial Disease (PAD), Ankle Brachial Index, Diagnostic Accuracy, Feasibility Studies
- Trial name
- AUTO-PAD (NCT07850349)
- Testing
- MESI mTablet, BlueDop vascular Expert (BlueDopVE)
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Knowledge of Nursing Process, Diagnostic Accuracy
The Effect of Escape Room on Nursing Process
This study aimed to examine the effects of the escape room approach on nursing process knowledge and diagnostic accuracy among nursing students.
- Conditions
- Knowledge of Nursing Process, Diagnostic Accuracy, Nursing Student
- Trial name
- NCT07707713
- Testing
- Escape room
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Differential Diagnosis, Diagnostic Accuracy
Evaluation of One-Shot Vision Differential Diagnosis (OSVDE) and Multi-Step Conversational Non-Inferiority (MSCNE) in AI Medical Interviewing
This study evaluates the diagnostic performance of a multimodal artificial intelligence (AI) system (AIMD.1) using de-identified medical images and semi-synthetic patient simulations.
- Trial name
- OSVDE-MSCNE (NCT07470463)
- Testing
- AI Diagnostic System (AIMD.1)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Magic Health Inc. (d.b.a. Nolla Health)
Patellar Tendinopathy, Diagnostic Accuracy
Textural Analysis and Effect of ROI Size on Infrared Thermography in Athletes With Patellar Tendinopathy
Patellar tendinopathy (PT) is a common knee disorder, particularly among elite athletes, with a reported prevalence of approximately 14.2%.
- Conditions
- Patellar Tendinopathy, Diagnostic Accuracy, Infrared Thermography
- Trial name
- NCT07095738
- Testing
- thermal images (IT)
- Where
- Spain
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Keratoconus, Refractive Surgery
AI-Orchestrated Workflow Versus Consultant Ophthalmologist for Refractive Surgery and Keratoconus Diagnosis (AEYE Trial)
Background and Rationale: Laser vision correction procedures, such as LASIK (Laser-Assisted In Situ Keratomileusis), PRK (Photorefractive Keratectomy), and SMILE (Small Incision Lenticule Extraction), are highly effective but…
- Conditions
- Keratoconus, Refractive Surgery, Machine Learning, Artifical Intelligence
- Trial name
- AEYE (NCT07096232)
- Testing
- Multi-Agent AI Diagnostic Workflow (AEYE)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Hazem Yassin Clinics
Brachial Plexus Anesthesia, Diagnostic Accuracy
Brachial Artery Pulsatility Index in Supraclavicular Block
Investigators aimed to evaluated accuracy of brachial artery doppler derived indices such as change in pulsatility index, resistive index, and waveform morphology in predicting successful supraclavicular block
- Trial name
- NCT06475638
- Testing
- brachial artery doppler
- Where
- Egypt
- Volunteers
- 89 people
- Sponsor
- Cairo University
Dental Caries, Detection
Comparing Fluorescent Starch Nanoparticles Rinse with ICDAS for Early Caries Detection in Children
The present study aims to evaluate the diagnostic accuracy of fluorescent starch nanoparticles caries detection rinse versus the International Caries Detection and Assessment System (ICDAS) in identifying early dental caries…
- Conditions
- Dental Caries, Detection, Fluorescence, Diagnostic Accuracy
- Trial name
- FSNCDR-ICDAS (NCT06761248)
- Testing
- Fluorescent Starch Nanoparticles Caries Detection Rinse
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Cairo University
Capnography, Nasogastric Tube
Diagnostic Accuracy of Capnography in Nasogastric Tube Placement
A prospective observational diagnostic study will be conducted to assess the sensitivity and specificity of using capnography in detecting the correct placement of nasogastric tubes using the reference standards of radiography…
- Conditions
- Capnography, Nasogastric Tube, Diagnostic Accuracy
- Trial name
- NCT05817864
- Testing
- Capnography
- Where
- China
- Volunteers
- 390 people
- Sponsor
- Chinese University of Hong Kong
Optical Biopsy, Colonic Dysplasia
Diagnostic Accuracy of Real-time Optical Biopsy
Differentiating neoplastic tissue from healthy tissue is fundamental for both early diagnosis during endoscopic examinations and radicality of the oncological interventions.
- Conditions
- Optical Biopsy, Colonic Dysplasia, Diagnostic Accuracy
- Trial name
- INSTASCOPE (NCT05858970)
- Volunteers
- 27 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Diagnostic Accuracy
Role of Lung Ultrasound in Confirmation of Correct Double Lumen Endotracheal Tube Placement in Thoracic Surgeries
to assess the efficacy of lung ultrasound versus conventional auscultation method and fiberoptic bronchoscopy in confirmation of double lumen tube position
- Trial name
- NCT04740385
- Testing
- Lung auscultation, Fiberoptic bronchoscopy, Lung Ultrasound
- Where
- Egypt
- Volunteers
- 117 people
- Sponsor
- National Cancer Institute, Egypt
Endometrial Cancer, Liquid Biopsy
Cell-free DNA Methylation for Endometrial Cancer
Liquid biopsy is challenging for the diagnosis of endometrial cancer. In this study, investigators perform the methylation testing of host DNA, namely, BHLHE22, CELF4, HAND2, and ZNF177, in the peripheral serum to discover the…
- Conditions
- Endometrial Cancer, Liquid Biopsy, DNA Methylation, Cervical Cytology
- Trial name
- NCT04651738
- Testing
- DNA methylation testing
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Lei Li
Cervical Cancer Screening, p16 Protein
Immunohistochemical Staining of p16 for the Screening of Cervical Cancer
Cyclin kinase inhibitor P16INK4A has overexpression in cervical cancer, and hence becoming an alternative method for cervical cancer screening.
- Conditions
- Cervical Cancer Screening, p16 Protein, Cytology, High-risk Human Papillomavirus
- Trial name
- NCT04650711
- Testing
- p16 protein expression
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Lei Li
Sarcoma, Soft Tissue Tumors
Magnetic Resonance Imaging or Ultrasound in Soft Tissue Tumors (MUSTT)
Adult soft tissue sarcomas (STS) are rare tumours with an estimated incidence averaging 5/100 000/year in Europe. The prognosis of soft tissue sarcomas is dominated by local recurrence and distant metastasis.
- Conditions
- Sarcoma, Soft Tissue Tumors, Ultrasound, Magnetic Resonance Imaging
- Trial name
- MUSTT (NCT02834585)
- Testing
- Ultrasound
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Genova
Patient Satisfaction, Diagnostic Accuracy
Evaluation of Patient Comfort and Image Quality in Magnetic Resonance Imaging
The aim of this prospective monocentric study is to evaluate the patient comfort in MRI and to measure examination conditions and factors that may affect the image quality and thus the diagnostic accuracy.
- Trial name
- NCT02726594
- Where
- Switzerland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Zurich