Clinical trials: Diagnostic Equipment
Alzheimer Disease, Mild Cognitive Impairment
Dementia Signal Development Study of Nautilus NeuroWave TM for the Detection of Dementia
This study is being performed to generate data regarding brain vibration /oscillation differences between individuals with dementia and normal controls.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Frontotemporal Lobar Degeneration, Memory Disorders
- Trial name
- NCT02333942
- Testing
- Nautilus NeuroWaveTM System
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Jan Medical, Inc.
Infertility
Tachykinin and Kisspeptin Expression in Human Granulosa and Cumulus Cells
The purpose of this project is to study the presence of expression differences - at RNA and protein level - of different members of the tachykinin family and kisspeptin and their receptors, between fertile women and infertile…
- Trial name
- NCT02877992
- Testing
- Ovarian puncture
- Where
- 2 sites in Spain
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Vida Recoletas Sevilla
Chronic Myeloid Leukemia (CML)
Study of CD38 and CD56 in Chronic Myeloid Leukemia
Chronic myeloid leukemia is a myelo-proliferative neoplasm characterized by abnormal proliferation of myeloid cells. There is an accumulation of mature granulocytes in the blood and bone marrow.
- Trial name
- NCT07740603
- Testing
- cd 38 and cd 56
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Breast Cancer
Breast Computed Tomography (CT) as a Diagnostic Tool
Lay Summary The American Cancer Society has recommended that all women over the age of 40 have an annual mammogram for many years. This recommendation has been associated with a substantial decrease in breast cancer deaths.
- Trial name
- NCT00957307
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Emory University
Dry Eyes
Validating the Diagnostic Accuracy of Mediview 2.0 Software as an Image Analysis Tool of Meibomian Glands
Non-contact meibography is a useful tool in assessing the health of meibomian glands in patients. Instead of using normal light in contact meibography, non-contact meibography utilises infra-red (IR) light.
- Trial name
- NCT01991132
- Testing
- MediView 2.0 software
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Malocclusion
Validation of AI-Based Cephalometric Analysis in Orthodontics
This study is designed to evaluate whether artificial intelligence can analyze cephalometric images in orthodontics as a reliable tool for diagnosis and treatment planning.
- Trial name
- AI-CEPH (NCT07315152)
- Testing
- Artificial Intelligence-Driven Cephalometric Analysis
- Where
- Egypt
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Lower Urinary Tract Symptoms
Primary Care Management of Lower Urinary Tract Symptoms in Men
The PriMUS Study aims to develop a clinical decision support tool to help GPs more accurately diagnose and manage LUTS in men. The study will recruit 880 men across three research hubs in Bristol, Newcastle and Wales.
- Trial name
- PriMUS (NCT03520673)
- Testing
- Urodynamics
- Where
- United Kingdom
- Volunteers
- 725 people, healthy volunteers welcome
- Sponsor
- Cardiff University
Premature Ejaculation
THE IMPACT OF VITAMIN B12 TREATMENT ON EJACULATORY FUNCTIONS IN MEN: SYMPTOMATIC RELIEF AND IMPROVED OUTCOMES
Aim: To investigate whether intramuscular B12 treatment has an effect on ejaculation in male patients with B12 deficiency. Methods: Male patients who were diagnosed with vitamin B12 deficiency in the internal medicine outpatient…
- Trial name
- VITAMIN B12 (NCT07036497)
- Testing
- Vitamin B12
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- OZGUR EKICI
Diagnoses Disease
Evaluation of an Innovative Speech-enabled Translator in Emergency Settings
Survey-based satisfaction, performance and technical features evaluation of a speech-enabled fixed-phrase translation tool (BabelDR) in an emergency department.
- Trial name
- NCT04788966
- Testing
- the translation tool BabelDr
- Where
- Switzerland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Short Stature, Growth Hormone Deficiency
The IGFBP-3 Stimulation Test: A New Tool for the Diagnosis of Growth Hormone Deficiency in Children.
This project is designed to answer the question: Is there an acute IGFBP-3 response in normal children? Our specific hypothesis states that under the influence of growth hormone secretagogues, intact IGFBP-3 molecule will undergo…
- Trial name
- NCT00235599
- Testing
- IGFBP-3 Stimulation Test
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Atypical Hemolytic Uremic Syndrome, Membranoproliferative Glomerulonephritis
Developing a Pipeline to Employ RNA-Seq as a Complementary Diagnostic Tool in Rare Diseases
This project aims to identify, through RNA-Seq technology, the genetic alterations underlying undiagnosed rare diseases in pediatric and adult patients with early onset and with negative WES.
- Conditions
- Atypical Hemolytic Uremic Syndrome, Membranoproliferative Glomerulonephritis, Autosomal Dominant Polycystic Kidney, Healthy
- Trial name
- ANTHEM (NCT05996731)
- Testing
- Skin biopsy
- Where
- Italy
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Long COVID
Utilizing Novel Blood RNA Biomarkers as a Diagnostic Tool in the Identification of Long COVID-19
The Primary objective of this study is to determine, using unblinded samples, if it is possible to develop an algorithm for the classification of specific blood RNA from patients with long COVID together and separately from the…
- Trial name
- NCT06311435
- Testing
- RNA Biomarker Blood Test
- Where
- 3 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- MaxWell Clinic, PLC
Pregnancy
Hysteroscopy for Pregnancy of Unknown Location
About 10% of early pregnancies can not be visualized by transvaginal ultrasound (TVU) on first visit and are classified as pregnancy of unknown location (PUL).
- Trial name
- NCT02637739
- Testing
- hysteroscope
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Jaundice, Neonatal
Evaluation of a Smartphone Based Diagnostic Tool to Assess Neonatal Jaundice in a Mexican Population
This corss-sectional study aims to test the performance and accuracy of the Picterus JP screening device in newborns with different skin types.
- Trial name
- NCT05623553
- Testing
- Picterus Jaundice Pro
- Where
- Mexico
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Picterus AS
AD
The Use of EEG in Alzheimer's Disease, With and Without Scopolamine - A Pilot Study
The objective of this study is to compare the electroencephalography (EEG) responses of three distinct groups of individuals to scopolamine: 1) a group of Alzheimer Dementia (AD) patients, 2) a group of individuals suffering from…
- Trial name
- NCT02273895
- Testing
- Scopolamine
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Mentis Cura
Post Prandial Hypoglycemia
Validation of a Diagnostic Tool for Postprandial Hypoglycaemia in Patients After Roux en Y Gastric Bypass Surgery
Roux-en-Y gastric bypass (RYGB) leads to weight reduction but has also some unwanted side effects. A part of this population will develop postprandial reactive hypoglycemia (PPRH).
- Trial name
- EDS (NCT03406312)
- Testing
- Post Prandial Hypoglycemia test
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent
Ulcerative Colitis, Pouchitis
Intestinal Ultrasound for the Evaluation of Pouchitis and Other Outcomes After Ileal Pouch-Anal Anastomosis
Intestinal ultrasound (IUS) has been studied in the evaluation of inflammatory bowel disease (IBD) and is increasingly used as a non-invasive, easy to use, cost-effective tool for point-of-care to assess disease activity and more…
- Trial name
- NCT06316999
- Testing
- Intestinal Ultrasound
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Premature Ejaculation
The Impact and Benefit of Physical Activity on Premature Ejaculation
The purpose of this study is to investigate the relationship between physical activity and PE, and determine whether moderate physical activity might delay ejaculation time or be an alternative treatment for PE.
- Trial name
- PE (NCT02844998)
- Testing
- physical activity, dapoxetine 30 mg on demand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Lung Collapse, Lung Diseases
The Accuracy of Pediatric Air Test as a Non-invasive Atelectasis Diagnostic Tool
HYPOTHESIS: During anesthetic pre-oxygenation with high FiO2, pulmonary atelectasis occur, especially in patients < 6 years old, where FRC and pulmonary closing volume may overlap.
- Conditions
- Lung Collapse, Lung Diseases, Atelectasis, Atelectasis Without Respiratory Distress Syndrome
- Trial name
- NCT04506203
- Testing
- Air test
- Where
- 3 sites in Argentina, Spain
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Paz
Diagnostic Equipment, Oximetry
The Sensing ET Tube
This proposal describes the development of a 'Sensing ET Tube'. This device will replace the standard endotracheal (ET) tube used in anaesthesia and in ventilated intensive care patients and provide key vital signs monitoring…
- Conditions
- Diagnostic Equipment, Oximetry, Pulse Rate
- Trial name
- SETT (NCT03250065)
- Testing
- Application of prototype sensor to a standard endotracheal tube
- Where
- 2 sites in United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- City, University of London