Clinical trials: Diagnostic Imaging Utilization
Opioid Use Disorder, Healthy
Adversity, Brain and Opioid Use Study
The way people process and remember information may be related to adverse childhood experiences and Opioid Use Disorder symptoms.
- Trial name
- NCT06355778
- Testing
- Magnetic Resonance Imaging (MRI), Computer Tasks
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Opioid-Related Disorders, Heroin Dependence
Combining Neuro-Imaging and Non-Invasive Brain Stimulation for Clinical Intervention in Opioid Use Disorder
The overarching goal of this project is to expand the traditional expertise in non-invasive neuromodulation at the University of Minnesota towards developing novel paired-neuromodulation approaches using transcrancial direct…
- Conditions
- Opioid-Related Disorders, Heroin Dependence, Morphine Dependence
- Trial name
- NCT04495673
- Testing
- Transcranial Direct Current Stimulation (tDCS), Cognitive Training
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Minnesota
Breast Cancer, Breast Benign
Development Of A Blood Test To Improve The Performance Of Breast Cancer Screening
The purpose of this study is to collect blood and tissue to help develop tests that might be able to detect cancer earlier. The investigator will be collecting these samples and reviewing test results from participants who have…
- Trial name
- NCT03372902
- Testing
- Breast MRI, Breast Mammogram, Blood draw
- Where
- 7 sites in United States
- Volunteers
- 628 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cocaine Use Disorder, Cocaine Dependence
Theta-Burst Stimulation as a Treatment for Reducing Cocaine Use
Objective: The goal of this clinical trial is to assess the tolerability of an accelerated intermittent theta burst stimulation (iTBS), a form of transcranial magnetic stimulation, intervention in participants with cocaine use…
- Trial name
- NCT02927236
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Alcohol Use Disorder
Psilocybin-assisted Therapy for Treatment of Alcohol Use Disorder
Note: The trial is only eligible for citizens of Denmark. The purpose of this project is to assess the treatment efficacy of a single high dose of psilocybin administered within a protocol of psychological support to patients…
- Trial name
- NCT05416229
- Testing
- Psilocybin, Maltodextrin
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Anders Fink-Jensen, MD, DMSci
Stroke
The Effects of Very Early Use of Rosuvastatin in Preventing Recurrence of Ischemic Stroke
It is anticipated that 548 subjects will be recruited from approximately 27 centres in South Korea. This is an investigator-sponsored, double-blind, placebo-controlled, randomized, multi-centre study to assess the effects of…
- Trial name
- EUREKA (NCT01364220)
- Testing
- Rosuvastatin
- Where
- 27 sites in South Korea
- Volunteers
- 318 people
- Sponsor
- Severance Hospital
Alcohol Use Disorder (AUD)
Brain Inflammation and Function in Alcoholism
Background: Brain inflammation due to high alcohol intake may affect thinking, memory, and concentration. Researchers want to measure this using positron emission tomography (PET).
- Trial name
- NCT02233868
- Testing
- connectivity, neuroinflammation, neurofunction
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders
3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer
RATIONALE: Diagnostic procedures, such as 3'-deoxy-3'-[18F] fluorothymidine (FLT) PET imaging, may help find and diagnose cancer.
- Conditions
- Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00935090
- Testing
- 3'-deoxy-3'-[18F]fluorothymidine
- Where
- United States
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Alzheimer Disease
Study of Tau Imaging With the Use of [18F]MK-6240 Tracer
The recent development of a PET tracer,[18F]MK-6240(an[18F]tau imaging agent,CerveauTechnologies)that has high affinity for the human phosphorylated tau deposits in AD brain offers new opportunities to investigate tau pathology.
- Trial name
- MKADAD (NCT04104659)
- Testing
- MK 6240
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tammie L. S. Benzinger, MD, PhD
Medication Adherence
Establishing Novel Antiretroviral Imaging for Hair to Elucidate Non-Adherence (ENLIGHTEN)
This is a pilot study to assess the feasibility, acceptability and appropriateness of delivery of the investigational "MedViewer" intervention in adult patients living with HIV who have been prescribed antiretroviral (ARV)…
- Trial name
- ENLIGHTEN (NCT04232540)
- Testing
- MedViewer report
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of North Carolina, Chapel Hill
Alcohol Abuse, Craving
Using Neurofeedback to Understand the Relationship Between Stress and Alcohol Consumption
In this research project, the aim is to discover the role specific brain networks play in the relationship between stress reactions and the desire for alcohol and alcohol consumption.
- Conditions
- Alcohol Abuse, Craving, Psychosocial Stressor, Neural Stress Response
- Trial name
- NeuStress (NCT06247306)
- Testing
- ScanSTRESS fMRI-paradigm (Streit et al., 2014), real-time fMRI neurofeedback
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Healthy
Use of Real-Time Functional Magnetic Resonance Imaging Neurofeedback to Improve Motor Function in Cerebellar Ataxia
This project will study the feasibility of motor rehabilitation in people with cerebellar ataxia using real-time functional magnetic resonance imaging neurofeedback (rt-fMRI NF) in conjunction with motor imagery.
- Trial name
- fMRI (NCT05436249)
- Testing
- Neurofeedback treatment, At-home therapy
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Ureteric Injury, Surgery
Fluorescent Imaging & Methylene Blue: Ureter Study
The main aim of this project is to assess whether intravenous methylene blue can help identify the ureters during open and laparoscopic (keyhole) surgery.
- Conditions
- Ureteric Injury, Surgery, Surgery--Complications
- Trial name
- NCT03177070
- Testing
- Methylene Blue
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Lung Cancer
The Use of Molecular Radiogenomics in Non-small Cell Lung Cancer
Lung cancer is currently the leading cause of cancer-related mortality worldwide, and the dominant histopathology is non-small cell lung cancer (NSCLC).
- Trial name
- NSCLC (NCT05541744)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Intraoperative Ureter Injury
Open-label Study to Evaluate Nerindocianine as a Surgical Aid in Ureter Delineation During Minimally Invasive Surgery
Phase 2, multicenter, efficacy and safety study evaluating the use of nerindocianine for the delineation of abdominopelvic ureter anatomy via near infrared fluorescence imaging during minimally invasive lower abdominal surgery…
- Trial name
- NCT04636567
- Testing
- Nerindocianine for injection
- Where
- 2 sites in United States
- Sponsor
- Li-Cor, Inc.
Alcohol Use Disorder (AUD), Alcoholism
Repetitive Transcranial Magnetic Stimulation for Alcohol Use Disorder
This study looked at whether repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation treatment, could help adults with alcohol use disorder when added to their usual treatment.
- Trial name
- NCT07755046
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Taiwan
- Volunteers
- 9 people
- Sponsor
- Ting-Gang Chang
Hyperparathyroidism, Primary
Autofluorescence in Surgery for Primary Hyperparathyroidism
The study aims to test if autofluorescence imaging (AF) is a useful surgical aid during parathyroidectomy (PTX) for primary hyperthyroidism (PHPT).
- Trial name
- NCT06230380
- Testing
- Surgery with autofluorescence
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aarhus University Hospital
Nicotine Dependence
The Effect of Varenicline on D2/D3 Receptor Binding in Smokers
This study will evaluate effects of treatment with varenicline, a smoking cessation drug, on the dopaminergic system by using Positron Emission Tomography (PET) imaging with new radioligand, [11C]-(+)-PHNO.
- Trial name
- NCT01632189
- Testing
- Varenicline
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Centre for Addiction and Mental Health
Cannabis Use
Pilot Study Repetitive Transcranial Magnetic Stimulation (rTMS) in Cannabis Craving
Background: Cannabis, also known as marijuana, is a commonly abused drug. There is no approved medication to treat cannabis addiction. The desire to use cannabis often increases when seeing others use it or seeing pictures of it.
- Trial name
- NCT01031290
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Sponsor
- National Institute on Drug Abuse (NIDA)
Liver Neoplasms
Assessment of Indocyanine Green as a Near-Infrared Fluorescent Contrast Agent for Image-guided Liver Surgery
This is a prospective, monocentric, non-randomized, phase I-II study. The goal is to assess the faisability and the capabilities of fluorescence imaging in hepatic surgery, and specially to help the surgeon while performing liver…
- Trial name
- HEPATOFLUO (NCT01738217)
- Testing
- Fluobeam
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre Leon Berard