Clinical trials: Diagnostic Role
Breast Cancer
Contrast-Enhanced Spectral Mammography (CESM)
The study's objective is to compare the diagnostic accuracy of the contrast-enhanced mammography (CEM) , considering as reference the classification obtained with Vacuum Assisted Breast Biopsy (VABB).
- Trial name
- CESM (NCT06311695)
- Testing
- Contrast Enhanced Mammography
- Where
- Italy
- Volunteers
- 263 people
- Sponsor
- European Institute of Oncology
Arrhythmogenic Right Ventricular Cardiomyopathy
The Role of High Density Surface ECG in the Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
The diagnosis of Arrhythmogenic right ventricular cardiomyopathy can be difficult. The 80 lead ECG may increase the specificity and sensitivity in diagnosing this potentially life threatening inherited cardiac condition.
- Trial name
- NCT02291393
- Testing
- 80 lead ECG
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Prostate Cancer
The Role of Social Comparisons in Coping and Quality of Life Following a Prostate Cancer Diagnosis
Social comparisons may function as a coping strategy, but their role in coping and quality of life has not been well characterized.
- Trial name
- NCT01176526
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Postmenopausal Bleeding
Role of MRI in Diagnosis of Postmenopausal Bleeding Causes
The aim of the study is to determine the diagnostic performance of MRI of endometrial pathology in postmenopausal women with postmenopausal bleeding
- Trial name
- NCT06004908
- Testing
- MRI
- Volunteers
- 36 people
- Sponsor
- Assiut University
Acute Appendicitis, Appendicitis Perforated
Bilirubin Levels to Diagnose Appendicitis and Predict Appendiceal Perforation
The goal of this study is to learn if serum bilirubin levels can aid in the diagnosis of acute appendicitis and predict appendiceal perforation
- Trial name
- NCT06956638
- Testing
- Non-interventional
- Where
- Nepal
- Volunteers
- 98 people
- Sponsor
- Nepalese Army Institute of Health Sciences
Leukemia, Promyelocytic, Acute
A Randomized Trial Assessing the Roles of AraC in Newly Diagnosed APL Promyelocytic Leukemia (APL)
The first purpose of this randomized trial will be to compare the best treatment group of APL 93 trial (ATRA with early introduction of anthracycline-AraC chemotherapy, followed by 2 consolidation anthracycline-AraC courses and…
- Trial name
- NCT00591526
- Testing
- Arac
- Volunteers
- 250 people
- Sponsor
- Groupe d'etude et de travail sur les leucemies aigues promyelocytaires
Preeclampsia
microRNAs Role in Pre-eclampsia Diagnosis
Pre-eclampsia is one of the most threatening pregnancy complications. So far neither a secure, competent therapy for PE nor effective biomarkers for a premature discovery has been achieved.The aim of our study was to identify…
- Trial name
- NCT03562715
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Interstitial Lung Disease
The Role of KL-6 in the Clinical Diagnosis of ILD
The purpose of the study is to evaluate the significance of KL-6 as a biomarker in the clinical diagnosis of interstitial lung disease (ILD) by detecting serum KL-6 levels among patients with ILD, and comparing them to the…
- Trial name
- NCT02197364
- Volunteers
- 1,190 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Fetal Conditions, Maternal; Procedure
A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures
In this research study, the investigators want to learn more about the role of new innovative surgical devices, the Karl Storz Curved and Straight Fetoscopes for in-utero surgery.
- Conditions
- Fetal Conditions, Maternal; Procedure, Pregnancy Related, Twin to Twin Transfusion Syndrome
- Trial name
- NCT06056635
- Testing
- Karl Storz Curved Scope, Karl Storz Straight Scope
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital
Neuroendocrine Tumors
Evaluation of the Diagnostic and Prognostic Role of PET (PET/CT and PET/MRI) in Neuroendocrin Tumors.
Neuroendocrine tumors (NETs) constitute approximately 0.5% of malignancies. To date, diagnosis at an increasingly early stage of the disease is possible thanks to recent technological advances in biomedical imaging.
- Trial name
- NCT06159920
- Testing
- diagnostic accuracy
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS San Raffaele
Hydrocephalus, Normal Pressure Hydrocephalus
The Role of the Glymphatic System Avaluated Thourgh mr Imaging in the Diagnosis and Management of NPH
The goal of this observational study is to evaluate the role of DTI-ALPS in the diagnostic and therapeutic management of NPH The main questions it aims to answer are: Whether the glymphatic system (GS) is actually impaired in NPH…
- Trial name
- GLINFANPH_2021 (NCT06857136)
- Where
- Italy
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
OSA
Ambulatory Versus Conventional Approach Diagnosing OSA
Very few studies have examined different models of care involving initial ambulatory home-based diagnosis in diagnosing obstructive sleep apnea (OSA), identifying patients who benefit from continuous positive airway pressure…
- Trial name
- NCT01828216
- Testing
- Home sleep study, conventional polysomnography
- Where
- China
- Volunteers
- 316 people
- Sponsor
- Chinese University of Hong Kong
Diabetes Mellitus, Adult-Onset, Diabetes Complications
Pancreatic Cancer Can be Detected by Adrenomedullin in New Onset Diabetes Patients
Pancreatic Cancer is a leading cause of cancer-related death. To date, only one fifth of patients at diagnosis is presented resectable because the diagnosis is often delayed making the 5-year survival of this disease globally…
- Conditions
- Diabetes Mellitus, Adult-Onset, Diabetes Complications, Carcinoma, Pancreatic Ductal, Pancreatic Neoplasm
- Trial name
- PaCANOD (NCT02456051)
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- University of Roma La Sapienza
Hypersensitivity
Role of Skin Tests for the Diagnosis of Immediate Hypersensitivity Reactions Due to Iodinated Contrast Media
The purpose of this trial is to study the diagnostic role of skin test in immediate reactions to iodinated radiocontrast media.
- Trial name
- NCT00819494
- Testing
- Skin tests with radiocontrast media
- Where
- Thailand
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Bile Leakage
Diagnostic Role of the "White Test" With Lipidic Solution in the Early Intraoperative Identification of Open Bile Ducts for the Prevention of Bile Leakage After Liver Resection (BiLe -Trial)
Bile leakage (BL) is the most frequent complication after liver resection. This study is to investigate the role of intraoperative administration of SMOFlipid 20% (fat emulsion which allows intraoperative identification of open…
- Trial name
- BiLe (NCT04523701)
- Testing
- "white" test" (= the administration of SMOFlipid retrograde through the cystic duct)
- Where
- 5 sites in Switzerland
- Volunteers
- 210 people
- Sponsor
- Giulia Manzini
Adnexal Torsion
Role of Preoperative D-dimer Levels in the Diagnosis of Adnexal Torsion
Adnexal torsion is the fifth most common gynecologic emergency. Thirty percent of all cases of adnexal torsion occur in females younger than 20 years.
- Trial name
- NCT06324565
- Testing
- D-Dimer test
- Where
- 9 sites in Austria, Italy and 1 more
- Volunteers
- 130 people
- Sponsor
- IRCCS Burlo Garofolo
Lung Transplant
Alveoscopy, Endoscopic Confocal Microscopy and Lung Rejection, Parenchymal Lung Diseases in Vivo
Lung transplantation is indicated when end-stage lung diseases no longer respond to available standard therapy, making life expectancy short and associated with disability.
- Trial name
- NCT01033201
- Testing
- Confocal imaging
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Mayo Clinic
Lung Cancer
The Role of Sedation Technique in EBUS-TBNA
There is a paucity of data concerning the impact of the sedation technique used for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) on diagnostic accuracy.
- Trial name
- NCT02245295
- Testing
- Moderate Sedation for EBUS/TBNA, General anesthesia for EBUS/TBNA
- Where
- Switzerland
- Volunteers
- 232 people
- Sponsor
- University of Zurich
Mild Cognitive Impairment, Alzheimer Disease
INTERCEPTOR Project: From MCI to Dementia
In the next years a number of phase 2-3 trials which utilize experimental drugs possibly disease modifying for Alzheimer Dementia will reach their conclusion.
- Trial name
- INTERCEPTOR (NCT03834402)
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Catholic University of the Sacred Heart
Knee Injuries, Anterior Cruciate Ligament Injuries
The Roles of MRI, DYNEELAX and Stress X-ray in First-Line Diagnosis of Cruciate Ligament Injury
Background: Cruciate ligament tears are clinically diagnosed by detection of anterior or posterior tibial translation on physical examination; however, this manual method of assessment is imprecise, subjective, and not…
- Conditions
- Knee Injuries, Anterior Cruciate Ligament Injuries, Knee Ligament Injury, Knee Arthritis
- Trial name
- NCT06259773
- Testing
- knee stability test (DYNEELAX)
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Kaohsiung Veterans General Hospital.