Clinical trials: Diagnostic Role
Hypersensitivity
Role of Skin Tests for the Diagnosis of Immediate Hypersensitivity Reactions Due to Iodinated Contrast Media
The purpose of this trial is to study the diagnostic role of skin test in immediate reactions to iodinated radiocontrast media.
- Trial name
- NCT00819494
- Testing
- Skin tests with radiocontrast media
- Where
- Thailand
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Benign Prostate Hypertrophy(BPH), Prostate Cancer (Adenocarcinoma)
Investigation of the Diagnostic Role of miRNAs in PCa and BPH
Prostate cancer(PCa) is the second most common cause of cancer-related death in men after lung cancer. Diagnostic methods such as measurement of serum Prostate-specific antigen (PSA) levels used in the clinic still cannot…
- Trial name
- NCT06726070
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Food Allergy, Food Allergy in Children
Understanding the Immune System's Role in Tree Nut and Peanut Allergies: Key Biomarkers for Diagnosis and Treatment Monitoring and Treatment Targets
Peanut and tree nuts belong to the main elicitors of pediatric food allergy and are the main cause of near fatal reactions in children requiring emergency management.
- Conditions
- Food Allergy, Food Allergy in Children, Food Allergy Peanut, Tree Nut Allergies
- Trial name
- Markers4Care (NCT06554691)
- Where
- 2 sites in Luxembourg
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
Colonic Polyps, Esophageal Diseases
Confocal Probe-based Endoscopic Imaging, Colorectal Cancer, Gastrointestinal (GI) Pathologies
The recently developed endoscopic Confocal probe microscopy system allows imaging of surface epithelium during ongoing endoscopy (upper and lower) with the potential of immediate diagnosis of various GI pre-malignant and…
- Trial name
- ASGE-FNDT-1 (NCT00874263)
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Early Diagnosis, Cancer
Role of Genomic Imprinting in Cancer Diagnosis
The current research focus for cancer diagonosis is classical genetics, named "driving genes". However, not all cancer patients have typical genetic alterations, especially at early stage.
- Conditions
- Early Diagnosis, Cancer, Biomarker, Genomic Imprinting
- Trial name
- NCT03882684
- Testing
- In-situ imprinting detection
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Chinese Alliance Against Lung Cancer
Colo-rectal Cancer
Role of Programmed Death Ligand 1 in Colorectal Cancer
1. - Evaluation of diagnostic importance of soluble programmed death ligand-1 in patient with recently diagnosed as Colorectal cancer at different stages of disease . 2.
- Trial name
- SPDL1 (NCT07088341)
- Testing
- elisa
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Erectile Dysfunction
Role of Intima-media Thickness in Determining Arteriogenic Erectile Dysfunction
Erectile dysfunction.
- Trial name
- NCT03038659
- Testing
- Penile Duplex
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Adam International Hospital
Females Undergoing PGD Technology for Medical Conditions
Isolation of Cell Free Fetal DNA From Spent Culture Medium and Its Potential Role for Preimplantation Genetic Diagnosis (PGD).
Preimplantation genetic testing for chromosomal screening is, at present, the most reliable method to assess the genetic status of preimplantation embryos.
- Trial name
- NCT06084377
- Testing
- Preimplantation Genetic Screening
- Where
- Syria
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Damascus University
Chronic Obstructive Pulmonary Disease, Smoker Lung
Lung Elastrosonography in Diagnosis and Stratification of COPD and Fibrosis
Elastosonography is an advanced ultrasound technique, nowadays available in many portable systems, allowing to measure elasticity and stiffness of parenchymatous organs.
- Trial name
- ELAS-P-1 (NCT04149652)
- Testing
- Lung Elastosonography
- Where
- Italy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Abnormal Uterine Bleeding
Management of Uterine Leiomyomata and Adenomyosis
1. to determine the role of hysteroscopy and guided biopsy to differentiate between submucosal fibroids and adenomyosis confirmed by histopathological examination 2.
- Trial name
- NCT05153928
- Testing
- Norethisterone acetate
- Where
- 2 sites in Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ahmed Ali Mahmoud
Cervical Intraepithelial Neoplasia Grade 2, DNA Methylation
The Role of FAM19A4 and Hsa-mir-124 Methylation in Predicting Prognosis of Untreated Cervical Intraepithelial Neoplasia 2 (CIN 2)
High-risk precancerous cervical lesions are divided into stage 2 and 3 cervical intraepithelial neoplasia (CIN 2 and 3). CIN 3 represents a direct pre-stage of invasive cancer, has a high rate of progression and a high degree of…
- Trial name
- NCT05624827
- Testing
- Testing DNA methylation test for predicting prognosis of untreated CIN 2
- Where
- Slovenia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Maribor
Acute Appendicitis
Clinical Diagnosis of Acute Appendicitis with Normal WBCS Count with Role of Inflammatory Markers and Radiology
The aim of this study is to describe the proportion of pa-tients with normal preoperative inflammatorymarkers among patients with histopathologically proven acute appendicitis
- Trial name
- NCT06834958
- Testing
- Appendectomy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Immune Thrombocytopenia
Role of Acute Phase Proteins In Diagnosis of Immune Thrombocytopenia
Immune thrombocytopenia (ITP) are antibody-mediated disorders in which platelets are destroyed mainly through activating immunoglobulin (IgG) Fc receptors on phagocytes in the spleen and liver, eventually resulting in…
- Trial name
- NCT06715215
- Testing
- Acute phase proteins
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Role of Neurofilment in Diagnosis of Multiple Sclerosis
Neurofilament Light Chain as Diagnostic and Prognostic Marker in naïve Multiple Sclerosis Patients
Neurofilament protein detected in the serum appears to be a good marker for the extent of active neurodegeneration. Chitinase may also be a good marker reflecting the degree of astrocyte activation, or damage in active lesions…
- Trial name
- NFLMS (NCT06197841)
- Where
- Egypt
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pulsatile Tinnitus (Diagnosis)
Role of the Radiologist in Management of Pulsatile Tinnitus
The aim of this study is to detect the role of interventional radiology in management of Pulsatile tinnitus and to detect the best imaging modality for Diagnosis.
- Trial name
- NCT05338684
- Testing
- Colour doppler,MSCT,MRI
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mohab Mohammed
Ultrasound, Muscle Disease
Role of Ultrasound in Diagnosis of Muscle Diseases
The study aims to provide a timely update on the role of combining clinical and neuromuscular ultrasound assessments in diagnosis and follow-up of various muscle diseases in clinical practice over 12 months period, and…
- Trial name
- NCT04233255
- Testing
- Neuromuscular Ultrasound (US), Electrophysiological studies, Seum CPK, CK-MM levels, Lactate dehydrogenase and alanine aminotransferase.
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acute Respiratory Infection
Children's Automated Respiration Monitor (ChARM) for Child Pneumonia Diagnosis by Community Health Workers in Mali
The primary objective of this study is to estimate the impact of a self-monitoring tool (ChARM), used as a teaching/monitoring device, on the CHWs respiratory rate counting accuracy when assessing children under the age of 5…
- Trial name
- NCT03457519
- Testing
- Children's Automated Respiration Monitor (ChARM)
- Where
- 2 sites in Mali
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Diego Bassani
Acute Myocardial Infarction, Acute Ischemic Stroke
DSS's Role in Evaluating the Diagnosis and Treatment System of Ischemic Cardiovascular and Cerebrovascular Diseases
Background: Acute ischemic cardiovascular and cerebrovascular diseases are a kind of diseases with high incidence, rapid progression, poor prognosis and high mortality and disability rate of the circulatory system, mainly…
- Conditions
- Acute Myocardial Infarction, Acute Ischemic Stroke, Ischemic Cardiovascular Disease
- Trial name
- NCT04359589
- Where
- 2 sites in China
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Nurse's Role
Effect of Standardized Patient Simulation on Nursing Students' Assessment, Diagnosis Skills, and Experiences
This randomized controlled study aims to determine the effect of teaching delivered through standardized patient simulation on nursing students' assessment and nursing diagnosis determination skills, as well as their learning…
- Trial name
- NCT07448168
- Testing
- Standardized Patient Simulation-Based Training, Traditional Training
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Acute Decompensated Heart Failure, Congestive Heart Failure Compensated
Role of USCOM in Adult Patients With Heart Failure
Objective: The Ultrasonic Cardiac Output Monitor (USCOM) is a non-invasive, quantitative method for measuring and monitoring cardiovascular haemodynamic parameters in patients. The aims of this study are: 1.
- Trial name
- NCT02289508
- Testing
- Ultrasonic cardiac output monitor, Echocardiography
- Where
- China
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong