Clinical trials: Dialysis Related Complication
Hyperphosphatemia Related to Chronic Kidney Disease
Study to Evaluate the Safety and Tolerability of Ferric Citrate in Children With Hyperphosphatemia Related to Chronic Kidney Disease
This study will be conducted to assess the safety and tolerability of ferric citrate in pediatric participants with hyperphosphatemia related to chronic kidney disease (CKD).
- Trial name
- NCT04523727
- Testing
- ferric citrate
- Where
- 14 sites in United States
- Volunteers
- 45 people
- Sponsor
- Keryx Biopharmaceuticals
Acute Kidney Injury, Kidney; Disease, Acute
Liberation From Acute Dialysis
The goal of the LIBERATE-D clinical trial is to improve outcomes for patients recovering from dialysis-requiring acute kidney injury (AKI-D).
- Conditions
- Acute Kidney Injury, Kidney; Disease, Acute, Dialysis Related Complication
- Trial name
- LIBERATE-D (NCT04218370)
- Testing
- Dialysis
- Where
- 4 sites in United States
- Volunteers
- 220 people
- Sponsor
- University of California, San Francisco
Chronic Kidney Diseases, End Stage Renal Disease
The Effect of Exercise on Blood Parameters Related to Dialysis Patients' Survival
The purpose of this study is to check if patients' exercise during their dialysis sessions can improve the blood parameters which affect the heart disease and osteoporosis, so that we can help patients live longer.
- Conditions
- Chronic Kidney Diseases, End Stage Renal Disease, Hemodialysis
- Trial name
- NCT04916743
- Testing
- Intradialytic exercise group
- Where
- 2 sites in Iran
- Volunteers
- 44 people
- Sponsor
- Pardis Specialized Wellness Institute
Kidney Failure, Chronic, Catheter-Related Infections
Study Assessing Safety & Effectiveness of a Catheter Lock Solution in Dialysis Patients to Prevent Bloodstream Infection
The purpose of this study is determine safety and effectiveness of Neutrolin, a catheter lock solution, for prevention of central venous catheter associated bloodstream infection in hemodialysis patients.
- Trial name
- NCT02651428
- Testing
- Neutrolin, Heparin
- Where
- 5 sites in United States
- Volunteers
- 806 people
- Sponsor
- CorMedix Therapeutics
Peritoneal Dialysis, Kidney Failure, Chronic
Relating Abdominal Complications With Peritoneal Pressure Estimation and Reporting
This is a prospective observational study in people treated with peritoneal dialysis for kidney failure to investigate whether estimated intraperitoneal pressure (eIPP) is correlated with non-infectious PD-related complications…
- Conditions
- Peritoneal Dialysis, Kidney Failure, Chronic, Hernia, Abdominal
- Trial name
- RAPPER (NCT06060951)
- Testing
- Estimated intraperitoneal pressure
- Where
- 2 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- Imperial College Healthcare NHS Trust
Cardiovascular Diseases, End Stage Renal Disease
Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates
The Canadian Australasian Randomized Trial of Screening Kidney Transplant Candidates for Coronary Artery Disease (CARSK) will test the hypothesis that eliminating the regular use of non-invasive screening tests for CAD AFTER…
- Conditions
- Cardiovascular Diseases, End Stage Renal Disease, Kidney Transplantation, Dialysis Related Complication
- Trial name
- CARSK (NCT03674307)
- Testing
- No screening, Regular Screening
- Where
- 22 sites in United States, Canada and 2 more
- Volunteers
- 3,306 people
- Sponsor
- University of British Columbia
Arteriovenous Graft, Arteriovenous Fistula
Validation of Arterio Venous Access Stage (AVAS) Classification
VAVASC trial is an observational multicentre study. The aim of this trial is to validate AVAS (arteriovenous vascular access stage) classification.
- Conditions
- Arteriovenous Graft, Arteriovenous Fistula, Dialysis Access Malfunction, Kidney Failure
- Trial name
- VAVASC (NCT04796558)
- Testing
- AVAS Classification
- Where
- Czechia
- Volunteers
- 800 people
- Sponsor
- Vascular surgery, University hospital Královské Vinohrady, Prague
Cannabis, Chronic Kidney Diseases
The Pharmacokinetics of Single Dose Oral Tetrahydrocannabinol and Cannabidiol
POT-GFR-PK is a single dose pharmacokinetic study oral tetrahydrocannabinol (THC) and cannabidiol (CBD) in healthy adult controls and individuals with chronic kidney disease including those treated with in-center hemodialysis.
- Conditions
- Cannabis, Chronic Kidney Diseases, Dialysis
- Trial name
- POT-GFR-PK (NCT05742724)
- Testing
- Tetrahydrocannabinol-Cannabidiol Combination
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- McMaster University
End Stage Renal Disease, Restless Legs Syndrome
Biotin Deficiency and Restless Legs Syndrome
Restless Leg Syndrome (RLS) is a common neuropathic disorder in patients with end stage renal disease (ESRD). Study Design: Because micronutrient depletion has been associated with RLS in ESRD and because the vitamin biotin is…
- Trial name
- NCT02011191
- Testing
- Biotin Supplementation, Sugar Pill
- Volunteers
- 49 people
- Sponsor
- Heidi Moretti, MS, RD
Dialysis, Fistula
Study of Pain, Anxiety and Complications Related to Cannulation of Arteriovenous (AV) Fistula in Chronic Hemodialysis Patients
A. Pain and other disadvantages of AV fistula cannulation can be limited by using the so-called buttonhole technique. B. Till present in our center catheters with cylindrical points are used for cannulation of AV fistulas with…
- Trial name
- NCT00544492
- Testing
- catheter for AV fistula cannulation
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Renal Failure, Sleep Disorder
The Relationship Between Sleep Disorders and Cytokine Levels Among Hemodialysis and Peritoneal Dialysis Patients
Sleep disorders are common in patients with end-stage renal disease on both hemodialysis and peritoneal dialysis and are associated with significant medical, psychological and social disturbances.
- Conditions
- Renal Failure, Sleep Disorder, Hemodialysis, Peritoneal Dialysis
- Trial name
- NCT00172471
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Cardiovascular Diseases, Carotid Intimal Media Thickness
Association of Mean Platelet Volume and Cardiovascular Disease in Children With End Stage Renal Disease.
Cardiovascular disease (CVD) is the major risk factor for death in end stage renal diseases (ESRD). Approximately 80% of ESRD patients have some degrees of left ventricular abnormalities at initiation of dialysis.
- Conditions
- Cardiovascular Diseases, Carotid Intimal Media Thickness, Left Ventricular Hypertrophy, Mean Platelet Volume
- Trial name
- NCT03759002
- Testing
- Imaging, Blood sampling
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Acute Renal Failure, Dialysis Related Complication
Simplified Regional Citrate Anticoagulation Protocols for CVVH, CVVHDF and SLED: a Pilot Study
The aim of the study are: 1) To evaluate the occurrence of acid-base alterations and the incidence of hypophosphatemia during different modalities of Renal Replacement Terapy (RRT) in critically ill patients [CVVH, CVVHDF and…
- Conditions
- Acute Renal Failure, Dialysis Related Complication, Hypophosphatemia, Hypomagnesemia
- Trial name
- NCT03976440
- Testing
- Renal Replacement Therapy (RRT) start
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Parma
Chronic Kidney Disease, End-stage Renal Disease
Home-based Exercise in Chronic Kidney Disease
A home-based exercise program will be implemented in three different groups of participants: advanced chronic kidney disease, end-stage renal disease in substitutive treatment hemodialysis or peritoneal dialysis.
- Trial name
- HBCKD-BCN (NCT03621176)
- Testing
- Home-based exercise
- Where
- Spain
- Volunteers
- 57 people
- Sponsor
- Cardenal Herrera University
End Stage Renal Disease, Hemodialysis Patients
Association Between Dose Dialysis by Kt and Mortality
The aim of this study is to assess whether patients receiving current recommendations of an adequate dialysis dose by Kt adjusted for body surface area improved survival at 24 months compared to those who do not get it, as well…
- Trial name
- NCT01932853
- Where
- Spain
- Volunteers
- 6,129 people
- Sponsor
- NephroCare Spain
Chronic Kidney Disease
Post-authorization Safety Study in CKD Subjects Receiving HX575 i.v.
Cumulative follow-up with HX575 epoetin alfa to prospectively monitor the incidence of relevant drug-related adverse events and EPO-related lack of efficacy among Chronic Kidney Disease (CKD) subjects receiving HX575 epoetin alfa…
- Trial name
- EPO-PASS (NCT00632125)
- Testing
- HX575 recombinant human erythropoietin alfa
- Where
- 114 sites in Austria, Bulgaria and 8 more
- Volunteers
- 1,695 people
- Sponsor
- Sandoz
End-stage Renal Disease, Peritoneal Dialysis
The Relationship Between Aortic Pulse Wave, Aortic Calcification and Peripheral Artery Occlusion Disease in Peritoneal Dialysis Patients
Cardiovascular disease (CVD) is the leading cause of mortality in patients with end-stage renal disease (ESRD), which means that it is important to find out risk factors of CVD in order to prevent or treat it.
- Conditions
- End-stage Renal Disease, Peritoneal Dialysis, Aortic Calcification, Peripheral Artery Occlusion
- Trial name
- NCT01945203
- Where
- Taiwan
- Volunteers
- 174 people
- Sponsor
- National Taiwan University Hospital
Patient Readmission, Arthroplasty, Replacement, Knee
A Study of the Effect of a Nurse Navigator Program on High Risk Patients
The purpose of this study is to examine if educational intervention in high risk patients can lead to decreased hospital readmissions when compared to patients who are not in the intervention program.
- Conditions
- Patient Readmission, Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip, Heart Failure
- Trial name
- NCT05592847
- Testing
- Nurse Navigator Program
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Mayo Clinic
End Stage Renal Disease, Peritoneal Dialysis
Chlorhexidine Gluconate Versus Mupirocin Ointment in the Prevention of Peritoneal Dialysis-Related Infection
This pilot study aims to evaluate effectiveness, safety, and cost-utility of chlorhexidine gluconate (CHG)-soaked cloths compares to mupirocin ointment and exit site usual care (normal saline) with aseptic technique in prevention…
- Trial name
- COSMO-PD (NCT02547103)
- Testing
- Chlorhexidine gluconate-soaked cloths, Normal saline, mupirocin ointment
- Where
- Thailand
- Volunteers
- 354 people
- Sponsor
- Chiang Mai University
Chronic Kidney Failure, Renal Dialysis
Health Related Quality of Life and Cognitive Function Among Norwegian Dialysis Patients
The purpose of this study is to assess health related quality of life and its predictors among chronic dialysis patients and to assess cognitive function using 3 different tests.
- Trial name
- NCT00806130
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Norwegian University of Science and Technology