Clinical trials: Diaphragmatic Electromyography
Respiratory Muscles, Electromyography
Electromyographic Activity of the Respiratory Muscles During Neostigmine or Sugammadex Enhanced Recovery After Neuromuscular Blockade
It was recently shown that neostigmine reversal was associated with increased atelectasis and that high-dose neostigmine was associated with longer postoperative length of stay and with an increased incidence of pulmonary edema…
- Trial name
- REDNESII (NCT02403063)
- Testing
- Sugammadex, Neostigmine, Neostigmine-sugammadex
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Onze Lieve Vrouw Hospital
Esophageal Cancer
Efficacy of Inspiratory Muscle Training on Respiratory Performance in Patients With Esophageal Cancer Receiving Combined Modality Therapy
The purpose of this study is to investigate the effectiveness of inspiratory muscle training (IMT) on respiratory performance in patients with esophageal cancer during combined modality therapy.
- Trial name
- NCT03099629
- Testing
- inspiratory muscle training
- Where
- Taiwan
- Volunteers
- 6 people
- Sponsor
- Mackay Memorial Hospital
Cervical Spinal Cord Injury
Combined Therapeutic Air Mixture and Electrical Stimulation to Improve Breathing and Hand Function in Spinal Cord Injury
The goal of this clinical trial is to determine whether people with paralysis due to a spinal cord injury can benefit from breathing short intermittent bouts of air with low oxygen (O2) combined with slightly higher levels of…
- Trial name
- AIHH+tSCS (NCT06101199)
- Testing
- Acute Intermittent Hypercapnic Hypoxia, Transcutaneous spinal cord stimulation
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Infant, Newborn, Disease
Predicting Infant Extubation Using Diaphragm Surface Electromyography
This study aims to assess whether the electrical signal of the diaphragm (diaphragm electromyogram) and the ratio of that to tidal volume (amount of air breathed in and out of the lungs) can predict which infants will be…
- Trial name
- EMG (NCT02878993)
- Testing
- Recording of diaphragm EMG
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- King's College London
COPD
Analyse the Correlation Between sEMG and EMGdi
The most significant pathophysiology change of COPD patients is persistent incompletely reversible airflow obstruction and increased lung volume. As a result, the work of breathing(WB) and neural respiratory drive (NRD)increased.
- Trial name
- NCT03268616
- Testing
- inspiratory threshold load device and NPPV
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Prolonged Air Leak, Phrenic Nerve
Postoperative Effects of Intraoperative Temporary Phrenic Nerve Paralysis in Lung Resection Surgery
This prospective clinical study aimed to evaluate the postoperative effects of temporary phrenic nerve paralysis induced by intraoperative phrenic nerve crush during lung resection surgery.
- Conditions
- Prolonged Air Leak, Phrenic Nerve, EMG
- Trial name
- PNCrush (NCT07259031)
- Testing
- İntraoperative phrenic nerve compression
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ferdane Melike Duran
Premature Birth
Changes in Respiratory Effort in Preterm Infants
Continuous Positive Airway Pressure (CPAP) is used to treat preterm infants with an immature respiratory center and having respiratory distress. CPAP requires intensive care monitoring and special qualified staff.
- Trial name
- NCT02014493
- Testing
- High Flow Nasal Cannulae (HFNC), Continuous Positive Airway Pressure (CPAP)
- Where
- Norway
- Volunteers
- 21 people
- Sponsor
- St. Olavs Hospital
Diaphragm Injury, Muscle Weakness
Electromyography for Diaphragm Effort
Mechanical ventilation may be necessary to save the life of a patient due to an accident, pneumonia or surgery. The ventilator then temporarily takes over the function of the respiratory muscles.
- Conditions
- Diaphragm Injury, Muscle Weakness, Weaning Failure, Physiological Stress
- Trial name
- Edi2Pdi (NCT03580720)
- Testing
- Inspiratory threshold loading protocol
- Where
- Netherlands
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Ultrasound, Transcutaneous EMG
Comparing Electromyography of the Diaphragm With Ultrasound in Neonates and Children With Respiratory Support
Background of the study: Increased work of breathing, potentially leading to respiratory insufficiency, resulting in the need of (non-) invasive respiratory support is the most common observed problem in the neonatal - and…
- Conditions
- Ultrasound, Transcutaneous EMG, Diaphragm, Neonate
- Trial name
- PROCEDURES (NCT05965830)
- Testing
- Diaphragm ultrasound
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Leiden University Medical Center
Diaphragm Dysfunction
Ultrafast Ultrasound for the Functional Assessment of the Diaphragm
The aims of the current study are as follows: i) Investigate the relationships between indices derived from ultrafast ultrasound imaging and Pditw, ii) Investigate the relationships between indices derived from ultrafast…
- Trial name
- ECHOSTIM-EFR (NCT05265351)
- Testing
- Transdiaphragmatic pressure measurement, EMG
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Institut de Myologie, France
ARDS
Mechanical Ventilation and Respiratory Muscle Work of Breathing in Acute Respiratory Distress Syndrome (ARDS) Patients
The purpose of this study is to demonstrate that mechanical ventilation guided by the diaphragm EMG signal (also know as neurally adjusted ventilatory assist [NAVA]) is superior compared to pressure support and pressure control…
- Trial name
- NCT01289600
- Testing
- Mechanical ventilation
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- University Medical Center Nijmegen
Esophageal Cancer
Effect of Concurrent Chemoradiation Therapy on Respiratory Muscle Performance, Lung Function and Functional Capacity in Patients With Local Esophagus Cancer
The purpose of this study is to investigate the effect of concurrent chemoradiation therapy on respiratory muscle performance, lung function and functional capacity in patients with local esophagus cancer.
- Trial name
- NCT03120572
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Mackay Memorial Hospital
Heart Failure
Pathophysiological Mechanisms of Activity-Related Dyspnea in Heart Failure: A Pilot Study
Dyspnea (breathlessness) on exertion is the most prevalent and distressing symptom of heart failure (HF). Nevertheless, the mechanisms of dyspnea in HF remain poorly understood.
- Trial name
- NCT02007486
- Testing
- Cardiopulmonary Exercise Testing
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- McGill University
Amyotrophic Lateral Sclerosis
Electrophysiology and Ultrasound of Respiratory Muscles and Respective Nerves to Predict Respiratory Insufficiency in ALS
Respiratory insufficiency is a common complication in amyotrophic lateral sclerosis (ALS). Survival can be prolonged with noninvasive ventilation (NIV).
- Trial name
- NCT06841341
- Testing
- electromyography, ultrasonography, Arterial blood gas analysis
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Jagiellonian University
Respiratory Disease
Surface Respiratory Electromyography Measurements During Treadmill Exercise in Stable Patients With COPD
To evaluate the compatibility and correlation between noninvasive surface respiratory electromyography and invasive transesophageal diaphragmatic electromyography measurements, as facilitating indicators of neural respiratory…
- Trial name
- NCT03238209
- Testing
- Exercise testing
- Volunteers
- 20 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Respiratory Failure, Cardiac Failure
Mechanical Ventilation Controlled by the Electrical Activity of the Patient's Diaphragm - Effects on Cardiac Performance
Neurally adjusted ventilatory assist (NAVA) is a new concept of mechanical ventilation. NAVA delivers assist to spontaneous breathing based on the detection of the electrical activity of the diaphragm.
- Trial name
- NCT00647361
- Testing
- Neurally adjusted ventilatory assist (NAVA) provided by a commercially available mechanical ventilator (Servo i, Maquet Critical Care, Solna, Sweden).
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Systemic Sclerosis, Diaphragm Defect
Muscular Respiratory Involvement and Systemic Sclerosis
Dyspnea in systemic sclerosis (ScS) constitute a major factor of functional disability. Intensity of dyspnea is sometimes discordant with objectives data from cardiopulmonary involvements, suggesting unknown additional factors.
- Conditions
- Systemic Sclerosis, Diaphragm Defect, Respiratory Insufficiency, Pulmonary Function Test
- Trial name
- SIROCO (NCT04118725)
- Testing
- Pulmonary function test
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Poitiers University Hospital