Clinical trials: Diaphragmatic Function
Injury of Diaphragm, Mechanical Ventilation Complication
Using Ultrasound to Study Respiratory Muscle Function in Critically Ill Patients
Mechanical ventilation can be life saving strategy for patients with respiratory failure due to a variety of reasons. Once the underlying illness has resolved, intensive care doctors have to take a decision on when the patient is…
- Conditions
- Injury of Diaphragm, Mechanical Ventilation Complication, Critical Illness
- Trial name
- NCT03139695
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Abdominoplasty, Diaphragm
Gastroesophageal Reflux and Respiratory Function in Patients Undergoing Abdominoplasty
The objective of this observational study is to compare parameters of diaphragmatic mechanics, respiratory muscle function, and thoracoabdominal kinematics among women with gastroesophageal reflux disease (GERD) and a history of…
- Conditions
- Abdominoplasty, Diaphragm, Respiratory Mechanics, Gastroesophageal Reflux Disease
- Trial name
- NCT07868562
- Testing
- Assessment of anthropometric and sociodemographic data and clinical history, Assessment of Symptoms, Quality of Life, and Physical Activity, Spirometric assessment
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Congenital Diaphragmatic Hernia
Microbiome and Volatile Organic Compounds in Patients With CDH
Despite improved prenatal diagnostics and therapeutic possibilities, congenital diaphragmatic hernia (CDH) represents a cross-disciplinary challenge.
- Trial name
- CDHVOCS (NCT03787160)
- Testing
- initial VOC, initial fecal microbiome, initial pulmonary microbiome
- Where
- Austria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Irritable Bowel Syndrome, Healthy Subjects
Application of Diaphragmatic Breathing in Patients With Disorders of Gut-brain Interaction
Patients with disorders of gut-brain interaction (DGBI) often present gastrointestinal symptoms that do not show noticeable irregularities in standard examinations.
- Conditions
- Irritable Bowel Syndrome, Healthy Subjects, Functional Gastrointestinal Disorders, Laryngopharyngeal Reflux
- Trial name
- NCT06205446
- Testing
- Healthy subjects : abdominal breathing, Laryngopharyngeal reflux disease subjects : abdominal breathing, Dyspepsia subjects : abdominal breathing
- Where
- Taiwan
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Pulmonary Disease, Chronic Obstructive
Measurements of Diaphragmatic Mobility on COPD Patients
To determine whether the COPD impairs the diaphragmatic mobility (DM), and verify improvements after an inpatient pulmonary rehabilitation (PR).
- Trial name
- NCT02838953
- Testing
- Pulmonary Rehabilitation
- Where
- Italy
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Casa Di Cura Villa Serena SpA
Low Back Pain, Chronic Low-back Pain
High Intensity Training to Improve Diaphragm Functioning in Persons With Chronic Nonspecific Low Back Pain
This randomized controlled trial aims to investigate 1) the effects of high intensity training (HIT) compared to moderate intensity training (MIT) on diaphragm muscle strength, -endurance, -fatigue and -activation, 2) to which…
- Conditions
- Low Back Pain, Chronic Low-back Pain, Chronic Pain
- Trial name
- NCT05384457
- Testing
- High intensity training, Moderate intensity training
- Where
- Belgium
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Paresis
Bupivacaine Versus Ropivacaine on Diaphragmatic Motility and Ventilatory Function
Background: Outpatient continuous interscalene brachial plexus blocks are used to control pain after shoulder surgery, with infusions of 0.125% bupivacaine or 0.2% ropivacaine.
- Trial name
- NCT02059070
- Testing
- Ropivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Anesthesiology WSU/DMC-NorthStar
Healthy Individuals (Controls)
Effects of Combined Exercise Training Modality
This study aims to investigate the effects of combined Inspiratory Muscle Training and aerobic exercise on diaphragm and pulmonary functions, respiratory muscle function, performance, and body composition
- Trial name
- NCT06742372
- Testing
- combined inspiratory and aerobic exercise training, aerobic exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Gazi University
Athletic Performance, Muscle Oxygenation
Effects of Core and Inspiratory Muscle Training on Muscle Oxygenation and Athletic Performance İn Young Soccer Players
The purpose of this randomized controlled trial is to investigate the effects of core training and inspiratory muscle training (IMT) on muscle oxygenation and athletic performance in youth male soccer players aged 15-18.
- Conditions
- Athletic Performance, Muscle Oxygenation, Respiratory Function
- Trial name
- NCT07657065
- Testing
- Core Training Program, Inspiratory Muscle Training (IMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istinye University
Diaphragm Issues
Comparison of the Interscalene Block Alone Versus Combined With Superior Truncus Block During Shoulder Surgery in Diaphragmatic Function
Primarily, This study aims to compare between interscalene block alone versus combined with superior truncus block in producing diaphragmatic paralysis and Secondarily aims to evaluate 1. Effect on the pulmonary function. 2.
- Trial name
- NCT07338630
- Testing
- Regional anesthesia in shoulder surgery
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Healthy
Neofunctional Deep Breathing for Stress Modulation
The goal of this pilot randomized clinical trial is to learn if a single session of Neo-Functional diaphragmatic breathing can stimulate vagotonia and help to restore a state of relaxation after acute stress in healthy adult…
- Trial name
- SIRED (NCT07023211)
- Testing
- Neo-Functional diaphragmatic breathing, Social touch
- Where
- Italy
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo
Respiratory Physiology
Deformation of the Diaphragm Zone of Apposition
The assessment of the work of the respiratory muscles is a fundamental clinical data in intensive care, especially to guide the management of patients requiring ventilatory support.
- Trial name
- ZADSPECTRA (NCT04424277)
- Testing
- diaphragm ultrasound
- Where
- France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Saint Joseph Saint Luc de Lyon
Diaphragm Thickness, Dyspnoea
Abdominal Air-Pressure Resistance Versus Abdominal Weight Training for Improving Diaphragm Function in Healthy Young Adults
This study aims to compare the effects of abdominal air pressure resistance training, abdominal weight training, and breathing exercises on diaphragmatic strength, endurance, and physiological responses in young healthy adults.
- Trial name
- NCT07795905
- Testing
- Abdominal Air Pressure Resistance Training, Abdominal Weight Training (AWT), Breathing Exercise Control (BE)
- Where
- United Arab Emirates
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Volleyball Players
Diaphragmatic Facilitation and Upper Extremity Performance in Volleyball Players
The diaphragm contributes to both respiration and trunk stabilization. Effective diaphragmatic function may support postural control, force transfer, and upper extremity performance during dynamic activities.
- Trial name
- NCT07784517
- Testing
- Diaphragmatic Facilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istinye University
Healthy Individuals
Effects of Diaphragm-releasing Techniques on the Lumbar Spine and Diaphragmatic Function in Healthy Women
The aim of this study was to evaluate the immediate effects of diaphragmatic release techniques on posterior chain flexibility and lumbar spine amplitude. Respiratory muscle strength and chest cavity mobility in healthy women.
- Trial name
- NCT03065283
- Testing
- Diaphragm lift, Relaxation of the diaphragm pillars
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Ceara
Sports Physical Therapy, Athletic Injuries
Acute Effects of Inspiratory Muscle Load on Diaphragmatic Recovery in Athletes
This randomized controlled trial investigates the acute effects of inspiratory muscle warm-up and fatigue on diaphragmatic function in professional basketball players.
- Conditions
- Sports Physical Therapy, Athletic Injuries, Healthy
- Trial name
- NCT07046637
- Testing
- Inspiratory muscle fatigue group, Inspiratory muscle warm-up group
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Sierra Varona SL
Healthy
Study of the Diaphragmatic Function by Transient Elastography (ELASTODIAPH)
The study of diaphragmatic function is usually measured by the pressures and volumes generated by contraction of the diaphragm, which is often difficult (cumbersome technique, difficulty to obtain a perfect cooperation of the…
- Trial name
- ELASTODIAPH (NCT03313141)
- Testing
- Ultrasound
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Healthy
Effects of Non-invasive Ventilation on Function Diaphragmatic and Caval Distension
Introduction: Understanding how the applicability of non-invasive ventilation can directly affect the anatomy and diaphragmatic function, as well as the opening diameter of the inferior vena cava in healthy individuals is…
- Trial name
- NCT06384027
- Testing
- Non-invasive ventilation
- Where
- Brazil
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Obesity & Overweight, Childhood Obesity
Combined Inspiratory Muscle Training and Functional High-Intensity Interval Training in Boys With Obesity
Childhood obesity is associated with reduced cardiorespiratory fitness, impaired exercise tolerance, and altered respiratory mechanics.
- Trial name
- IMT and HIIT (NCT07810361)
- Testing
- Inspiratory Muscle Training, Functional High-Intensity Interval Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Pes Planus, Diaphragm Issues
The Relationship Between Pes Planus, Diaphragm, Postural Control, and Plantar Pressure
Our primary aim is to compare diaphragm function (resting thickness, activity/resting thickness ratio indicating contractility), postural control, and plantar pressure between individuals with pes planus and healthy controls…
- Conditions
- Pes Planus, Diaphragm Issues, Plantar Pressure, Postural Control
- Trial name
- NCT06491212
- Testing
- Determination of Foot Deformity Level, Foot Function Index, UFAA-International Physical Activity Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University