Clinical trials: Diaphragmatic Function
Ventilated Patient in Intensive Care
Effectiveness of Diaphragmatic Function and Parasternal Intercostal Muscles Functions as Predictors for Successful Weaning From Mechanical Ventilation
Critically ill patients frequently develop respiratory muscle dysfunction that may contribute to difficult and prolonged weaning from mechanical ventilation.
- Trial name
- NCT07630662
- Where
- Egypt
- Volunteers
- 77 people
- Sponsor
- Ain Shams University
BIPAP Biphasic Intermittent Positive Airway Pressure, Diaphragm Issues
The Effect of BIPAP on Diaphragmatic Function
This research is designed to evaluate how long-term treatment with Bilevel Positive Airway Pressure (BiPAP) influences diaphragm function in patients with Chronic Obstructive Pulmonary Disease (COPD) who suffer from chronic…
- Conditions
- BIPAP Biphasic Intermittent Positive Airway Pressure, Diaphragm Issues, Ultrasound Diagnostics, COPD (Chronic Obstructive Pulmonary Disease)
- Trial name
- NCT07193017
- Testing
- BIPAP
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Demiroglu Bilim University
Asthma
Effects of Energy Conservation Exercises Versus Circuit Training in Asthmatic Patients
The aim of this study was to evaluate the Effects of energy conservation exercises versus circuit training on dyspnea, functional capacity and quality of life in asthmatic patients.
- Trial name
- NCT07508280
- Testing
- Energy Conservation Technique, Circuit Training
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Diaphragm
Trans Thoracic Ultrasound to Assess Diaphragmatic Function in Stable COPD Versus Bronchial Asthma.
Assessment of diaphragmatic function (excursion, thickness variation, thickness ratio) in COPD and bronchial asthma patients. Assessment of presence of correlation between diaphragmatic dysfunction and pulmonary function.
- Trial name
- NCT06348745
- Testing
- ultrasound
- Volunteers
- 80 people
- Sponsor
- Assiut University
Esophageal Cancer
Efficacy of Inspiratory Muscle Training on Respiratory Performance in Patients With Esophageal Cancer Receiving Combined Modality Therapy
The purpose of this study is to investigate the effectiveness of inspiratory muscle training (IMT) on respiratory performance in patients with esophageal cancer during combined modality therapy.
- Trial name
- NCT03099629
- Testing
- inspiratory muscle training
- Where
- Taiwan
- Volunteers
- 6 people
- Sponsor
- Mackay Memorial Hospital
Postoperative Pain
RISS Versus ESP Block in Laparoscopic Cholecystectomy
This prospective randomized controlled trial aims to compare the analgesic efficacy and effects on diaphragmatic function of bilateral erector spinae plane (ESP) block and bilateral rhomboid intercostal-subserratus plane (RISS)…
- Trial name
- RISS-ESP-LC (NCT07655323)
- Testing
- Erector Spinae Plane Block, Rhomboid Intercostal-Subserratus Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ferit Yetik
Respiratory Insufficiency
Sonographic Evaluation of Diaphragmatic Function Under Nasal High-flow (NHF) and Non-invasive Ventilation (NIV) in Respiratory Insufficiency
The aim of the study is to investigate the influence of respiratory support on diaphragmatic function (O2, NHF, NIV). The effects on the diaphragm, the respiratory values (FEV1, respiratory rate) and the subjective well-being of…
- Trial name
- SENNI (NCT07050147)
- Testing
- Nasal high flow, NIV
- Where
- Germany
- Volunteers
- 35 people
- Sponsor
- Klinikum Emden
Covid19
Respiratory Muscle Function, Dyspnea, Exercise Capacity and Quality of Life in Severe COVID19 Patients
Further knowledge regarding sequelae in severe COVID-19 patients who have required ICU admission for invasive mechanical ventilation is still needed.
- Trial name
- NCT04853940
- Testing
- Data collection and clinical testing of subjects
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Respiratory Physiology
Deformation of the Diaphragm Zone of Apposition
The assessment of the work of the respiratory muscles is a fundamental clinical data in intensive care, especially to guide the management of patients requiring ventilatory support.
- Trial name
- ZADSPECTRA (NCT04424277)
- Testing
- diaphragm ultrasound
- Where
- France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Saint Joseph Saint Luc de Lyon
Weaning Mechanical Ventilation, Ultrasonography
The Relationship Between Diaphragm Function Assessed by Ultrasound and Weaning Success in Mechanically Ventilated Patients in the ICU
The diaphragm is the most important muscle involved in the respiratory system and is solely responsible for approximately 65-80% of vital capacity.
- Conditions
- Weaning Mechanical Ventilation, Ultrasonography, Intensive Care (ICU), Assesment of Diaphragmatic Function by Ultrasound to Predict Weaning Success in Mechanical Ventilated Intensive Care Unit Patients
- Trial name
- ICU (NCT07332403)
- Testing
- Diaphragm ultrasound before weaning procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Breathing Exercises
Comparative Effects of ACBT and Diaphragmatic Breathing on Pulmonary Function and Sputum Diary After CABG
To compare the effects of active cycle of breathing technique and diaphragmatic breathing on pulmonary functions and sputum diary after coronary artery bypass graf
- Trial name
- NCT05936788
- Testing
- Active cycle of breathing technique, diaphragmatic breathing
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Copd, Chest Disorders
Efficacy of Costal Mobilization Techniques and Manual Diaphragm Release Technique in Patients COPD
To evaluate the acute and chronic effects of costal mobilization techniques and diaphragmatic release in chest cavity kinematics, diaphragmatic mobility and functional capacity in patients with chronic obstructive pulmonary…
- Conditions
- Copd, Chest Disorders, Diaphragmatic Disorder
- Trial name
- NCT03022942
- Testing
- GROUP Costal mobilization & Diaphragm Release, GROUP Manual Diaphragm Release
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Universidade Federal de Pernambuco
Inflammatory Myopathies
Inspiratory Muscle Training in Patients With Inflammatory Myopathy
Inflammatory myopathies are rare autoimmune diseases leading to progressive muscle weakness, often including the respiratory muscles.
- Trial name
- NCT07274267
- Testing
- Inspiratory Muscle Training (IMT)
- Where
- Poland
- Volunteers
- 33 people
- Sponsor
- Józef Piłsudski University of Physical Education
Dyspnea; Asthmatic, COPD
Diaphragmatic Function as a Biomarker
Dyspnea is among the most common symptoms in patients with respiratory diseases such as Asthma, chronic obstructive pulmonary disease (COPD), Fibrosis, and Pulmonary Hypertension.
- Conditions
- Dyspnea; Asthmatic, COPD, Fibrosis, Pulmonary Hypertension
- Trial name
- DFUNBIO (NCT05903001)
- Testing
- Diaphragm Ultrasound, Intercostal Muscle Ultrasound, Borg scale
- Where
- Germany
- Volunteers
- 800 people
- Sponsor
- RWTH Aachen University
Diaphragm Thickness, Dyspnoea
Abdominal Air-Pressure Resistance Versus Abdominal Weight Training for Improving Diaphragm Function in Healthy Young Adults
This study aims to compare the effects of abdominal air pressure resistance training, abdominal weight training, and breathing exercises on diaphragmatic strength, endurance, and physiological responses in young healthy adults.
- Trial name
- NCT07795905
- Testing
- Abdominal Air Pressure Resistance Training, Abdominal Weight Training (AWT), Breathing Exercise Control (BE)
- Where
- United Arab Emirates
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Coronavirus, Inspiratory Muscle Training
Association of Inspiratory Muscle Training With HD-tDCS for Assistance to Patients With Long Covid-19
COVID-19 is an infectious disease which presents a heterogenous clinical presentation. Recent investigations suggest that people who were infected by COVID-19 often develop physical disabilities (i.e.
- Conditions
- Coronavirus, Inspiratory Muscle Training, Respiratory Infection, COVID-19
- Trial name
- NCT05359770
- Testing
- Active HD-tDCS, Control group
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Suellen Marinho Andrade
Respiratory Muscles, Respiration, Artificial
Visualization of Inspiratory Effort and Respiratory Mechanics to Promote Lung- and Diaphragm Protective Ventilation
This is a multicentre prospective cohort trial in adult and pediatric ICU patients. The investigators will measure the effect of a patient's inspiratory effort during mechanical ventilation on the lungs and diaphragm.
- Conditions
- Respiratory Muscles, Respiration, Artificial, Respiratory Function Tests
- Trial name
- VIREM (NCT05459116)
- Testing
- Placement of nasogastric balloon
- Where
- 3 sites in Belgium, Canada
- Volunteers
- 150 people
- Sponsor
- University Hospital, Antwerp
Heart Failure, Ischemic Myocardiopathy
Influence of Severe Heart Failure to Function and Molecular Biological Parameters of Catabolism in the Human Diaphragm and Peripheral Skeletal Muscle
Project aim is to quantify the influence of a severe therapy-refractory heart failure caused by ischemic or dilative myocardiopathy on the function of the diaphragm, its molecular biological parameters and on the M.
- Conditions
- Heart Failure, Ischemic Myocardiopathy, Dilatative Myocardiopathy
- Trial name
- LIPAMUS-HF (NCT02663115)
- Testing
- Biopsy of the diaphragmatic muscle, Skeletal muscle biopsy
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Norman Mangner
Mechanical Ventilation
Transcutaneous Electrical Diaphragmatic Stimulation in PMV Patients
Muscle atrophy and diaphragm dysfunction are common with prolonged mechanical ventilation (PMV). Electrical stimulation has been shown to be beneficial in severe chronic heart failure and chronic obstructive pulmonary disease.
- Trial name
- NCT04281810
- Testing
- transcutaneous electric diaphragm stimulation
- Where
- Taiwan
- Volunteers
- 59 people
- Sponsor
- Chang Gung Memorial Hospital
Virtual Reality, Congenital Diaphragmatic Hernia
Virtual Reality and Congenital Diaphragmatic Hernia
The study has been designed to investigate the effect of 12 weeks of using virtual reality based exercises on pulmonary functions, exercise capacity, functional performance, and quality of life in children with…
- Conditions
- Virtual Reality, Congenital Diaphragmatic Hernia, Children
- Trial name
- NCT05612503
- Testing
- Traditional physical therapy program, Virtual reality-based exercises
- Where
- Saudi Arabia
- Volunteers
- 52 people
- Sponsor
- Qassim University