Clinical trials: Diaphragmatic Injury
Athletic Injuries
Effects of Inspiratory Muscle Training on Diaphragm Thickness, Respiratory Muscle Strength and Balance in Dancers.
Dance is a performing art form consisting of sports and art intertwined and complex dynamic choreographic figures were handled aesthetically and physically of narrative.
- Trial name
- NCT04845802
- Testing
- Inspiratory muscle training(high-IMT group), Inspiratory muscle training(low-IMT group)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Abdominal Injury, Pelvic Fracture
Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients
Unrecognized abdominal and pelvic injuries can result in catastrophic disability and death. Sporadic reports of "occult" injuries have generated concern, and physicians, fearing that they may miss such an injury, have adopted the…
- Conditions
- Abdominal Injury, Pelvic Fracture, Genital Hemorrhage, Lumbar Spine Injury
- Trial name
- NEXUS AP CT (NCT04937868)
- Testing
- There are no interventions associated with this study
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- University of California, Los Angeles
Brain Injuries, Respiratory Failure
Epidural Spinal Cord Stimulation for Respiratory Recovery in Brain Injury
Patients with severe brain injury may develop impaired respiratory drive, diaphragm dysfunction, prolonged mechanical ventilation, and difficulty recovering spontaneous breathing.
- Trial name
- BREATH (NCT07766681)
- Testing
- Epidural Electrode Implantation
- Where
- 3 sites in China
- Volunteers
- 10 people
- Sponsor
- Zhongda Hospital
Respiratory Paralysis, Diaphragmatic Paralysis
Diaphragmatic Pacemaker in Tetraplegic Patients With Spinal Cord Injuries
Permanent dependency of breathing apparatus due to spinal cord injury is traditionally treated with different types of mechanical ventilation.
- Conditions
- Respiratory Paralysis, Diaphragmatic Paralysis, Spinal Cord Injury
- Trial name
- NCT01385384
- Testing
- NeuRx RA/4 diaphragmatic pacemaker
- Where
- 2 sites in Brazil
- Volunteers
- 5 people
- Sponsor
- University of Sao Paulo
Diaphragm Injury
Janus Kinase Inhibition to Prevent Ventilator-induced Diaphragm Dysfunction
We intend, with this study, to prove that blocking the molecular mechanisms whose blockade prevents VIDD in animals, will indeed prevent the development of VIDD in humans as well.
- Trial name
- NCT03681275
- Testing
- Tofacitinib 10 MG [Xeljanz]
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Stanford University
Proximal Humeral Fracture, Anesthesia, Regional
Optimized Costoclavicular Block for Elderly Proximal Humeral Fracture Surgery
Background: Proximal humeral fractures are common in elderly patients and often require surgical fixation (open reduction and internal fixation).
- Conditions
- Proximal Humeral Fracture, Anesthesia, Regional, Diaphragmatic Paralysis
- Trial name
- OptCCB (NCT07612514)
- Testing
- Costoclavicular Brachial Plexus Block, Interscalene Brachial Plexus Block, Superficial Cervical Plexus Block
- Where
- 3 sites in China
- Sponsor
- Shanghai Tong Ren Hospital
Shoulder Pain, Supraspinatus Tendinitis
MINIMUM EFFECTIVE VOLUME OF BUPIVACAİNE FOR ANTERIOR SUPRASCAPULAR NERVE BLOCK
Various local anesthetic volumes are used in the literature for anterior suprascapular nerve block (ASSB). There are different studies between 15 ml and 5 ml.
- Conditions
- Shoulder Pain, Supraspinatus Tendinitis, Bankart Lesions
- Trial name
- NCT05241977
- Testing
- anterior supra scapular nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- V.K.V. American Hospital, Istanbul
Rotator Cuff Injuries
ESP vs STB for Pain and Diaphragm Function for Shoulder Surgery
To compare the efficacy of pain control, shoulder function recovery, and degree of diaphragm palsy between erector spinae plane block at T2 level and superior trunk block after arthroscopic shoulder surgery
- Trial name
- NCT05822414
- Testing
- Erector spinae plane block
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Diaphragm Injury, Lung Transplant; Complications, Mechanical
Incidence, Risk Factors and Outcomes of Diaphragm Dysfunction After Lung Transplantation
The study is designed to characterize the changes in diaphragm function after lung transplantation.
- Conditions
- Diaphragm Injury, Lung Transplant; Complications, Mechanical, Respiratory Failure, Mechanical Ventilation Complication
- Trial name
- RADAR (NCT04103996)
- Testing
- Ultrasound, Respiratory function measurements
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University Health Network, Toronto
Diaphragm Injury
Laparoscopy Versus Clinical Follow up to Detect Diaphragm Injury
Title: A randomized prospective study comparing non operative management with laparoscopic treatment in patients with a diaphragm injury following left thoracoabdominal stab wounds.
- Trial name
- NCT01044550
- Testing
- Laparoscopy, Clinical follow up
- Where
- South Africa
- Volunteers
- 66 people
- Sponsor
- University of Cape Town
Mechanical Ventilation Complication, Diaphragm Injury
Respiratory Muscle Structure and Function in Mechanically Ventilated Patients and Long-term Outcomes
Air is normally pumped in and out of the lungs by the muscles that contribute to inhalation and exhalation, called the respiratory muscles.
- Conditions
- Mechanical Ventilation Complication, Diaphragm Injury, Lung Injury, Respiratory Insufficiency
- Trial name
- RESPIRE (NCT05857774)
- Testing
- Sonographic measurements, Physiological measurements, Biological measurements
- Where
- Canada
- Volunteers
- 230 people
- Sponsor
- University Health Network, Toronto
Respiratory Support
The ACCESSIT Study
The study is designed to characterize and monitor the structure, degree of activation and function of the different respiratory muscles during mechanical ventilation after spine trauma and spinal cord injury.
- Trial name
- ACCESSIT (NCT05207046)
- Testing
- Mechanical Ventilation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Unity Health Toronto
Quadriplegia
Study of Combined Intercostal and Diaphragm Pacing for Artificial Respiration in Quadriplegic Patients
OBJECTIVES: I. Determine whether combined intercostal muscle and diaphragm pacing can maintain full-time ventilatory support in patients with ventilatory dependent quadriplegia who are not candidates for phrenic nerve pacing…
- Trial name
- NCT00004415
- Testing
- Medlink spinal cord electrode
- Volunteers
- 5 people
- Sponsor
- Case Western Reserve University
ICU Acquired Weakness, Diaphragmatic Injury
Transcutaneous Electrical Diaphragmatic Stimulation in Critically Ill Elderly Patients
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- Trial name
- NCT04565002
- Testing
- Transcutaneous Electrical Diaphragmatic Stimulation
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- Centro Universitário Augusto Motta
Persistent Fetal Circulation Syndrome, Diaphragmatic Hernia
Antibody Secreting Cell and Cyotokine Profiles in Neonates on ECMO
Infants are placed on ECMO for correction of reversible respiratory failure. Often, because a few of the reasons for respiratory failure show us similar things in the baby, it is difficult to determine exactly which is causing…
- Conditions
- Persistent Fetal Circulation Syndrome, Diaphragmatic Hernia, Meconium Aspiration, Sepsis
- Trial name
- NCT00371241
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Health Science Center, Houston
Aphakia Due to Trauma, Eye; Rupture, Traumatic, With Loss of Intraocular Tissue
Clinical Outcomes of Implantationof Black Diaphragm Intraocular Lens in Complete Aniridia and Aphakia Due to Posttraumatic Eye Rupture
Purpose: To assess long-term outcomes of implantation of black diaphragmintraocular lens (BD IOL) in postraumatic aniridia and aphakia due to eye rupture.
- Conditions
- Aphakia Due to Trauma, Eye; Rupture, Traumatic, With Loss of Intraocular Tissue, Aniridia
- Trial name
- NCT03581864
- Where
- Poland
- Volunteers
- 14 people
- Sponsor
- Medical University of Lublin
Ventilator Induced Lung Injury
Percutaneous Temporary Placement of a Phrenic Nerve Stimulator for Diaphragm Pacing, a First in Human Trial
Study conducted to confirm phrenic nerve stimulation using the Lungpacer LIVE Catheter, confirm capture of the diaphragm and confirm that the diaphragm can be paced in synchrony with mechanical ventilator breaths.
- Trial name
- NCT02670460
- Testing
- LIVE Catheter
- Where
- Paraguay
- Volunteers
- 24 people
- Sponsor
- Lungpacer Medical Inc.
Diaphragm Injury, Lung Injury
Lung and Diaphragm-Protective Ventilation by Means of Assessing Respiratory Work
This study is designed to test a proposed strategy for lung- and diaphragm-protective ventilation (LDPV) in patients with acute hypoxemic respiratory failure.
- Conditions
- Diaphragm Injury, Lung Injury, Respiratory Insufficiency, Mechanical Ventilation Complication
- Trial name
- LANDMARK (NCT03612583)
- Testing
- Lung- and Diaphragm-Protective Ventilation
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- University Health Network, Toronto
Covid19, Diaphragm Injury
Respiratory Muscles After Hospitalisation for COVID-19
Fatigue and exercise intolerance after survived COVID-19-infection might be related to weakness of the respiratory muscles especially following invasive mechanical ventilation in the Intensive Care Unit.
- Trial name
- REMAP-COVID-19 (NCT04854863)
- Testing
- Comprehensive assessment of respiratory muscle function.
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- RWTH Aachen University
Congenital Diaphragmatic Hernia, Acute Kidney Injury
Incidence of Acute Kidney Injury and Risk Factors in Newborns With Congenital Diaphragmatic Hernia
The main aim of this project is to elucidate the incidence of acute kidney injury (AKI) in newborns with congenital diaphragmatic hernia during stay in the Pediatric intensive care unit. (PICU).
- Conditions
- Congenital Diaphragmatic Hernia, Acute Kidney Injury, Multiple Organ Failure, Pulmonary Hypertension
- Trial name
- NCT06050525
- Where
- Sweden
- Volunteers
- 109 people
- Sponsor
- Karolinska Institutet