Clinical trials: Diaphragms
Premature
dTDI During a SBT to Predict Extubation Failure in Preterm Infants
Weaning from mechanical ventilation is a critical issue and the diaphragmatic disfunction has been demonstrated to play an important role in extubation failure.
- Trial name
- NCT05865977
- Testing
- diaphragmatic tissue Doppler imaging，dTDI
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Wang Jianhui
Gastroesophageal Reflux, Hernia, Hiatal
Valvuloplasty as Alternative to Toupet Fundoplication for GERD
This monocenter randomized controlled trial aims to compare postoperative outcomes of a laparoscopic valvuloplasty with a Toupet fundoplication in patients with GERD with a maximum hiatal hernia of 3cm.
- Trial name
- VANTAGE (NCT02625077)
- Testing
- Laparoscopic gastroesophageal valvuloplasty, Laparoscopic Toupet fundoplication
- Where
- Netherlands
- Sponsor
- Meander Medical Center
Respiratory Muscle Function, Athletic Performance
Effects of Diaphragmatic Breathing Retraining in Combat Sport Athletes With Dysfunctional Breathing Patterns
Combat sport athletes often need to maintain a guarded posture, stabilize the trunk, react quickly, and control balance during contact or unexpected movement.
- Conditions
- Respiratory Muscle Function, Athletic Performance, Postural Balance
- Trial name
- NCT07717801
- Testing
- Diaphragmatic breathing training exercise, Usual training
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Cheng Kung University
Diaphragm Issues
Comparison of the Interscalene Block Alone Versus Combined With Superior Truncus Block During Shoulder Surgery in Diaphragmatic Function
Primarily, This study aims to compare between interscalene block alone versus combined with superior truncus block in producing diaphragmatic paralysis and Secondarily aims to evaluate 1. Effect on the pulmonary function. 2.
- Trial name
- NCT07338630
- Testing
- Regional anesthesia in shoulder surgery
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Respiratory Failure, Critical Illness
Double Triggering Asynchrony in Mechanically Ventilated Patients.
This observational study examined double triggering asynchrony in28ICU patients on mechanical ventilation. Researchers collected data on patient characteristics, health conditions, and outcomes to understand how this problem…
- Conditions
- Respiratory Failure, Critical Illness, Mechanical Ventilation
- Trial name
- NCT07380607
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Mansoura University
Breast Cancer Surgery, Breast Cancer Surgery Pain
Impact of High Thoracic Paravertebral Block on Diaphragmatic Function: a Prospective Study
The high thoracic paravertebral block is a regional anesthesia technique commonly used for oncologic breast surgery. Local anesthetic is injected into the paravertebral space to provide anesthesia and pain relief.
- Conditions
- Breast Cancer Surgery, Breast Cancer Surgery Pain, Hemidiaphragmatic Paralysis
- Trial name
- NCT07907692
- Testing
- High thoracic paravertebral block
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Paraesophageal Hernia
Effect of Hernia Sac Excision on Crural Tension in Paraesophageal Hernia Repair
Paraesophageal hernia can cause significant clinical symptoms, including reflux, chest pain, nausea, regurgitation, and even life threatening conditions such as bowel obstruction, and gastric volvulus.
- Trial name
- NCT07197619
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Corewell Health West
Rib Fractures
Low Dose Dexmedetomidine Versus Normal Saline in Multiple Fracture Ribs
In our study, we assess the diaphragmatic function, pain quality and anti-inflammatory properties between low dose infusion of dexmedetomidine normal saline in patients with multiple fracture ribs on conservative treatment.
- Trial name
- NCT04928300
- Testing
- Dexmedetomidine, 0.9% saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Respiratory Function Loss, Respiratory Complication
Shear-wave Elastography Compared to Respiratory Function Testing
The purpose of this study is to evaluate the relationship between transdiaphragmatic pressure (Pdi) and diaphragm shear-wave elastography (SWE) during state-of-the-art respiratory muscle testing including volitional efforts…
- Trial name
- NCT04959526
- Testing
- Shear-wave elastography
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cirrhosis of the Liver, Ascites
Ultrasound Assessment of Diaphragmatic Structure and Function in Patients With Liver Cirrhosis: A Point-of-Care Tool for Predicting Complications and Sarcopenia in Limited Resource Settings
The goal of this observational study is to learn how liver cirrhosis affects the diaphragm, the main muscle used for breathing, in adults.
- Conditions
- Cirrhosis of the Liver, Ascites, Pleural Effusion Disorder, Hepatocellular Carcinoma (HCC)
- Trial name
- NCT07667608
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assiut University
Patient With Radiotherapy (Linac MRI), Mobile Cancerous Lesion
Impact of Non-magnetic Screen Respiratory Self-guidance During MRI-guided Radiotherapy Sessions for Mobile Lesions
The patients eligible for the study are those treated by radiotherapy on Linac MRI for a mobile cancerous lesion (pancreas, liver, kidneys, adrenals, lung, adenopathy above or below the diaphragm ...).
- Trial name
- RespEcran (NCT05783908)
- Testing
- With non-magnetic screen
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Georges Francois Leclerc
PRE-HYPERTENSION
Additional Effects of Pilates Breathing and Diaphragmatic Breathing Combined With Moderate Intensity Continuous Treadmill Training on Blood Pressure, Chest Expansion, Pulmonary Function and Quality Of Life in Pre-hypertensive Patients
Pre-hypertension is defined as systolic blood pressure between 120-139mmHg or diastolic blood pressure between 80-89mmHg and is considered a risk factor for developing hypertension.
- Trial name
- NCT07529821
- Testing
- Treadmill Training (Moderate-intensity continuous training), Pilates Breathing, Diaphragmatic Breathing
- Where
- Pakistan
- Volunteers
- 45 people
- Sponsor
- Foundation University Islamabad
General Laparoscopic Surgery Candidate, Bariatric Laparoscopic Surgery Candidate
Usability and Performance Evaluation of the AutoLap System - a Feasibility Study
The main objectives of this study are to evaluate the ease of use and performance of the AutoLap system compared to human camera holder during general and bariatric laparoscopic surgeries.
- Trial name
- NCT02346552
- Testing
- AutoLap
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- M.S.T. Medical Surgery Technology LTD.
Low Back Pain
Effects of Diaphragmatic Manual Therapy in Chronic Low Back Pain
This study is a double-blind randomized clinical trial with two arms which aims to study the effects of diaphragmatic treatment in patients with nonspecific low back pain.
- Trial name
- NCT02343185
- Testing
- manual therapy with diaphragmatic treatment
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Cardenal Herrera University
Diastasis Recti Abdominis (DRA)
Diaphragm and Breathing Muscle Characteristics in Women With and Without Diastasis Recti Abdominis After Childbirth
Diastasis Recti Abdominis (DRA) is a common condition experienced postpartum, in which the abdominal muscles separate along the midline of the abdomen due to stretching and thinning of the linea alba.
- Trial name
- DRA-BREATH (NCT07389993)
- Testing
- Ultrasonographic assessment of the diaphragm, Inspiratory muscle testing
- Where
- Greece
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Patras
Diaphragm
The Impact of Diaphragmatic Breathing Instructions and Inspiratory Pressures on Diaphragm Contraction in Healthy Adults
This is a cross-sectional obsessional study. This study aims (1) to investigate the relationship between sternocleidomastoid muscle recruitment and diaphragm thickness fraction during increasing inspiratory resistance in healthy…
- Trial name
- NCT06347549
- Testing
- Various intensities of inspiratory muscle training
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
Pelvic Floor, Functional Constipation
The Effect of Pelvic Floor Muscle Training in Functional Constipation
The aim of this study is to examine the effect of individualized pelvic floor muscle training on symptoms, core muscle function, and quality of life in patients with functional constipation.The research is being conducted at the…
- Conditions
- Pelvic Floor, Functional Constipation, Biofeedback, Chronic Constipation
- Trial name
- NCT07603414
- Testing
- Lifestyle change training, Diaphragmatic Breathing Exercise, Pelvic Floor Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Selin Koşan
Surgery, Thoracic, Respiratory Diaphragm
Diaphragmatic Echography After Thoracic Surgery
The investigator evaluated diaphragmatic function in patients undergoing thoracic surgery. Diaphragmatic displacement was evaluated before surgery, 2 and 24 hours after surgery.
- Conditions
- Surgery, Thoracic, Respiratory Diaphragm, Complication, Postoperative
- Trial name
- OLVDD (NCT03347578)
- Testing
- Ultrasonography
- Volunteers
- 75 people
- Sponsor
- Università degli Studi di Ferrara
Stroke, Diaphragmatic Function
Diaphragmatic Function Description in Stroke Patients
Stroke is the leading cause of adult disability throughout the world. Motor function deficit is one of the common consequences. It is usually described for the peripheral muscles that there is a cortical representation…
- Trial name
- DISTROKE (NCT03626558)
- Testing
- ultrasound measures
- Sponsor
- Fondation Hôpital Saint-Joseph
Gastroesophageal Reflux Disease, Hiatal Hernia
Nissen and Gastroplasty in Gastroesophageal Reflux Disease (GERD)
Laparoscopic Nissen Fundoplication has established itself as the procedure of choice in the surgical management of the majority of patients suffering from gastroesophageal reflux disease (GERD).
- Conditions
- Gastroesophageal Reflux Disease, Hiatal Hernia, Barrett's Esophagus, Esophagitis
- Trial name
- NCT00872755
- Testing
- Nissen, Gastropexy
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- G. Hatzikosta General Hospital
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