Clinical trials: Diet, High-Fat
Health, Subjective
A Food Effect Study of FMTN on Healthy Chinese Adult Subjects
The primary objective of the study was to assess the effect of high-fat and low-fat meal on the pharmacokinetics of FMTN in Chinese adult healthy subjects.
- Trial name
- NCT04616716
- Testing
- FMTN
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Obesity
Effects of Two Hypocaloric Diets on Weight Loss
The investigators evaluated whether an energy-restricted protein diet with low glycaemic index carbohydrates and soluble fibers (LC-P-LGI) would be more effective than a conventional diet (LC-CONV) on weight-loss and related…
- Trial name
- NCT01312740
- Testing
- LC-P-LGI diet, LC-CONV
- Where
- France
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Ceprodi S.A. Kot
Intra-abdominal Fat, Metabolic Syndrome
Habitual Diet and Avocado Trial
The Habitual Diet and Avocado Trial will evaluate the effects of providing one avocado per day for recommended consumption over a 6 month period in a cohort of approximately 1000 free-living participants with increased waist…
- Conditions
- Intra-abdominal Fat, Metabolic Syndrome, High Cholesterol, Triglycerides High
- Trial name
- HAT (NCT03528031)
- Testing
- Intervention Daily Avocado
- Where
- 4 sites in United States
- Volunteers
- 1,008 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Low-Calorie Diet, Diet, High-Protein
The Effect of Diet Counseling for Low Calorie-High Protein on the Body Composition, Inflammation Marker, and Oxidative Stress Marker in Obese People With Weight Cycling
The world prevalence of obesity in adult population in 2014 was nearly 13% while in Indonesia, it has reached 32.9% in the same year. Obesity is an established risk factors for cardiovascular diseases.
- Conditions
- Low-Calorie Diet, Diet, High-Protein, Obesity; Pituitary, Weight Cycling
- Trial name
- NCT03374150
- Testing
- diet counseling
- Where
- 2 sites in Indonesia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Obesity, Diabetes
The Effect of Macronutrients in the Diet on Digestive and Cardiovascular Health
This study examined the effect of a 5-day HFD supplemented with specific fatty acids on gastrointestinal transit, appetite, food intake and substrate utilization.
- Conditions
- Obesity, Diabetes, Cardiovascular Diseases
- Trial name
- NCT01510223
- Testing
- Olive oil, Olive oil and fish powder, Olive oil and macadamia oil
- Where
- Ireland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Blood Glucose, High
Clinical Study to Evaluate the Short Time Efficacy of AP Green Tea Extract Affer High Fat, High Carbohydrate Diet
The objective of this clinical trial is to evaluate the short term effects of single dose AP green tea extracts in subjects with BMI (< 30 kg/m2) and fasting glucose level of > 100 mg/dL after high-fat/high-carbohydrate meal.
- Trial name
- NCT04850326
- Testing
- AP green tea extract
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Amorepacific Corporation
Healthy Volunteers
Trial of Chiauranib Capsule on Pharmacokinetics to Assess the Effect of High Fat Diet in Healthy Volunteers
The purpose of this study is to further study the pharmacokinetic characteristics of Chiauranib Capsule in Healthy Volunteers with High Fat Diet.
- Trial name
- NCT05346601
- Testing
- Chiauranib
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Chipscreen Biosciences, Ltd.
Pre-diabetes
High Protein Diet on Transcriptomic, Metabolomics, Hepatic and Pancreatic Fat Anatomy and Physiology in Asian Indians With Pre-diabetes
Diabetes/ prediabetes is a substantial problem in India not only because it itself can be associated with morbidities such as coronary artery disease but also because it is a point of importance for the prevention of other…
- Trial name
- NCT05925933
- Testing
- Intervention
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
Endocrine and Metabolic Responses to Exercise and Diets
Exercise Effects on Insulin, Gut Peptides, and Appetite
Determine whether the mid-day suppression of hunger and amplified increase in the release of glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide 1 (GLP-1) following morning exercise is due to increased fat…
- Trial name
- XFG (NCT01891617)
- Testing
- Exercise and diets
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Insulin Sensitivity/Resistance
Protective Effect of Exercise on Acute High-fat Overfeeding
Metabolic flexibility is the ability to switch rapidly from one substrate (i.e. fuel source) to another (e.g. fats to carbohydrates) in response to ingested foods.
- Trial name
- HFDEXC (NCT07633704)
- Testing
- High Fat Overfeeding, High Fat Overfeeding + Exercise
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- George Washington University
Lipid Metabolism Disorders, Sterols
Effect of Different Fat Enriched Meats on the Hepatic Cholesterol Synthesis
The objective of the study is to assess the effect of two diets with different fat composition on cholesterol metabolism. The study was a randomized cross-over trial where volunteers follow two study periods with different types…
- Conditions
- Lipid Metabolism Disorders, Sterols, Diet, High-Fat, Cholesterol
- Trial name
- NCT02259153
- Testing
- Changes in cholesterol metabolism, Lean red meat diet, Fat red meat diet
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Instituto Aragones de Ciencias de la Salud
Gene Expression
Impact of a Short-Term High Fat or Low Fat Diet on Intestinal Genes Expression Involved in the Cholesterol and Fatty Acid Metabolism
Dietary fat has been shown to modulate cholesterol and fatty acids homeostasis and several lines of evidence suggest that this effect is associated with changes in the regulation of different genes at the intestine level involved…
- Trial name
- DGENES (NCT01806441)
- Testing
- 3-days high fat diet, 3-days low fat diet
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Laval University
Obesity
Classic vs. High-Fat Intermittent Fasting Effects
Poor eating habits contribute to weight gain and obesity, leading to numerous metabolic issues such as diabetes and cardiovascular diseases.
- Trial name
- NCT06515639
- Testing
- Diet therapy for Classic IF diet group, Diet therapy for low carb-High fat IF diet group
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Overweight/Obese Women
Dietary Fatty Acid Composition and Obesity-related Metabolic Abnormalities
Individuals have a significant capacity to adapt to different environments by changing their core metabolic pathways. This adaptation is especially important in regards to diet.
- Trial name
- NCT01451970
- Testing
- High Fat Diet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Overweight, Obesity
Mono Unsaturated Fatty Acids in Obesity - Weight Maintenance and Prevention of Lifestyle Diseases in Obese Subjects.
The purpose of this study is to investigate the effect of three diets different in type and amount of fat in weight maintenance and prevention of life-style diseases in obese subjects.
- Trial name
- NCT00274729
- Testing
- Mono Unsaturated Fatty Acids in Obesity
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dietary Fat Reduction
Efficacy of a Stage-Matched Intervention Based on The Transtheoretical Model of Change in Dietary Fat Reduction
This study aims to examine the efficacy of a Stage-Matched Intervention based on The Transtheoretical Model of Change in dietary fat reduction among female high school students.
- Trial name
- NCT05949918
- Testing
- Stage-matched interventions
- Where
- Iraq
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Obesity, Overweight
Effect of Food Temperature and Diet Composition on Satiety, Satiety Hormones, Chewing Time and Neuronal Activity
Obesity and its related illnesses have become serious health issues, obesity is today the fifth most common cause of death. Obesity rate has dramatically enhanced in both male and female, and across all ages.
- Trial name
- NCT05822167
- Testing
- High Protein Meal at Cold Temperature, High Protein Meal at Warm Temperarute, High Protein Meal at Hot Temperature
- Where
- Pakistan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Overweight, Cardiovascular Diseases
Dietary Fat and High-Density Lipoprotein (HDL) Metabolism-Effect of Carbohydrate and Fat Intake
Generally, people with low levels of high-density lipoprotein (HDL) in blood are more likely to get heart disease than those who have normal or high levels.
- Trial name
- NCT01399632
- Testing
- Low Fat and High Carbohydrate Diet, High Fat and Low Carbohydrate Diet
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Healthy Subjects
Single Ascending Dose Study(SAD),Multiple Ascending Dose Study(MAD) , High-fat Diet Study (FE) of TJ0113 Capsules in Healthy Subjects
The study included three clinical studies, namely a single ascending dose (SAD) study, a multiple ascending dose (MAD) study, and a high-fat diet food effect (FE) study.
- Trial name
- NCT07394452
- Testing
- TJ0113 Capsules
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Hangzhou PhecdaMed Co., Ltd.
Overweight, Obesity
"Improving Diet, Exercise And Lifestyle (IDEAL) for Women" Study
Diets all share the same principle: eat less energy than you need. This results in weight loss. However, the weight loss is usually a combination of a loss of body fat and muscle mass.
- Trial name
- NCT00710398
- Testing
- Exercise - Aerobic and Resistance, Dietary - Caloric Restriction
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- McMaster University