Clinical trials: Diet Induced Thermogenesis
Increased Energy Expenditure, Increased Satiety
The Effect of Hydrolyzed Casein on Energy Expenditure and Subjective Appetite
The primary aim is to examine and compare the effects of hydrolyzed casein (HC), intact casein (IC) and intact whey protein (IWP) on diet-induced thermogenesis (DIT).
- Trial name
- HerKulES (NCT01677273)
- Testing
- Hydrolyzed casein, Intact casein, Intact whey protein
- Where
- Denmark
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Thermogenesis, Brown Adipose Tissue
Stimulation of Diet-Induced Thermogenesis by Cold-Exposure
Human fat tissue is essentially white fat, the main function of which is to store excess energy intake, and to release it when necessary.
- Trial name
- BAT&DIT (NCT01898949)
- Testing
- Cold Exposure
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Diet-induced Thermogenesis
Inter-Individual Variability in Early Diet-Induced Thermogenesis After a Standardized Meal
This study aims to characterize how individuals differ in their metabolic response to food intake, specifically focusing on early diet-induced thermogenesis (DIT).
- Trial name
- NCT07610759
- Testing
- Standardized Liquid Meal
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Brown Adipose Tissue, Metabolic Disease
Brown Adipose Tissue as Nutrient Buffer Through Diet Induced Thermogenesis
To test the hypothesis that active BAT improves metabolic health by buffering postprandial metabolites plasma metabolites and energy expenditure will be compared in volunteers with and without active BAT.
- Trial name
- BANDIT (NCT06078345)
- Testing
- Carbohydrate, Fat, Protein
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Obesity and Overweight
How Metabolism Affects Weight Loss and Gain
This study examines why some individuals with obesity have difficulty losing weight, whereas some lean individuals struggle to gain weight.
- Trial name
- NCT06860776
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Heat Stress, Diet Induced Thermogenesis
Carbohydrate or Protein Drinks Before Exercise in the Heat
This project examines whether consuming a high-protein or high-carbohydrate beverage before exercise in the heat impacts metabolism and heat balance during exercise, with the following research questions: 1.
- Conditions
- Heat Stress, Diet Induced Thermogenesis, Protein Consumption
- Trial name
- NCT07646990
- Testing
- Protein shake, Carbohydrate shake
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Providence College
Postprandial Metabolism, Healthy Volunteers
Postprandial Metabolic Responses to Sustainable and Non-Sustainable Meals in Healthy Young Men
This randomized crossover study evaluated the acute postprandial metabolic and hydration responses to two standardized lunch meals differing in nutritional quality and environmental footprint in healthy young men.
- Trial name
- THERMOS-LUNCH (NCT07808736)
- Testing
- Healthy-Sustainable Test Meal, Non-Sustainable Test Meal
- Where
- Italy
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Parma
Diet-induced Thermogenesis, Sensory Function
Sensory Stimulation as a Driver of Diet-induced Thermogenesis
This study aims to assess the influence of sensory stimulation on diet-induced energy expenditure by way of a clinical cross-over trial in 24 healthy participants either receiving a meal bolus with (orally) and without sensory…
- Trial name
- SENSATION (NCT07409025)
- Testing
- sensory exposure, sensory deprivation
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Healthy, Overweight and Obesity
Effect of Acute Intake of Meals Containing Higher vs. Lower Energy From Protein on DIT
The objective of this trial is to assess the effects of acute intake of mixed meals containing higher vs. lower energy from protein on diet induced thermogenesis (DIT) in adults with overweight or obesity.
- Trial name
- NCT06494449
- Testing
- Higher protein, Lower protein
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Dietary Habits
Can Food Timing Reduce Your Diabetes Risk?
The goal of this clinical trial is to test whether food timing impacts metabolic health in healthy participants. Participants will: complete 2 inpatient stays be provided with test meals have frequent blood draws
- Trial name
- NCT05862818
- Testing
- Day shift protocol - Diet order A-B, Day shift protocol - Diet order B-A, Night shift protocol - Diet order A-B
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Imbalance of Constituents of Food Intake, Healthy
The Effect of Phosphorus on Diet Induced Thermogenesis
The aim of the trial is to investigate the effect of ingestion of 75g of glucose (with or without phosphorus) on diet induced thermogenesis (using indirect calorimetry) and appetite (using visual analogue scales) in lean and…
- Trial name
- NCT02594787
- Testing
- Phosphorus
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Lebanese American University
Diet Induced Thermogenesis, Obesity Control
Thermic Effects of Some Scottish Plant Foods
Weight gain occurs because of imbalances in energy balance favouring energy intake. Whilst over 50% of a person's energy requirement goes towards the maintenance of physiological functions, around 40% is used for physical…
- Trial name
- ThermicFoods (NCT02937298)
- Testing
- Control Meal, Berry Treatment, Sea Buckthorn Treatment
- Where
- United Kingdom
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Caffeine-Induced Thermogenesis, Brown Adipose Tissue Activation
Caffeine-Induced Thermogenesis Assessed by Infrared Thermography
This study evaluated thermogenic and physiological responses to 200 mg of caffeine administered following a carbohydrate gel in healthy adults.
- Trial name
- NCT07868302
- Testing
- Carbohydrate Gel, Caffeine
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Istanbul Health and Technology University
Healthy
Effects of Dihydrocapsiate on Adaptive and Diet-Induced Thermogenesis With a High Protein Very Low Calorie Diet
The study is designed to determine the effects of a non-pungent supplement from sweet chilli pepper on resting metabolic rate and diet-induced thermogenesis (DIT) after a period of very low calorie intake over 4 weeks.
- Trial name
- NCT01142687
- Testing
- dihydrocapsiate capsule
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Prevention of Obesity
The Effect of Protein and Calcium on Weight Change and Blood Lipid Profile
The primary aim is to examine the effect of a high protein intake (from soy or whey protein) on weightmaintenance after weight loss in a group of predisposed (severe) obese persons.
- Trial name
- PROKA (NCT01561131)
- Testing
- Whey protein, Whey protein enriched with calcium, Soy protein
- Where
- Denmark
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Diet Induced Thermogenesis
Effect of Allulose on Diet-induced Thermogenesis
The objective of this study is to investigate the dose-response effect of allulose on diet-induced thermogenesis, substrate oxidation, glycemic response, and subjective appetite in healthy normal weight adults.
- Trial name
- NCT06515340
- Testing
- Allulose Dose 1, Allulose Dose 2, Allulose Dose 3
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Overweight, Obesity
Role of Dietary Protein on Satiety, Food Intake and Thermic Effect of Food
Objectives: To determine the effect of protein content of familiar breakfast meals on subjective appetite, food intake (FI), glycemic response and Thermic Effect of Food (TEF) in normal weight (NW) and overweight (OW)/obese (OB)…
- Trial name
- NCT02200796
- Testing
- Control Meal, Low Protein Meal, Moderate Protein Meal
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Obesity
The Role of Phosphorus in Diet Induced Thermogenesis (DIT) of Both Lean and Obese Subjects
The study aim at: Investigating the impact of phosphorus ingestion on DIT of lean and obese subjects consuming high carbohydrate meal.
- Trial name
- PinDIT (NCT02482142)
- Testing
- Effect of phosphorus
- Where
- Lebanon
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Diet-induced Thermogenesis, Brown Adipose Tissue Activation
Creatine Effect on Brown Adipose Tissue Activation
Pre-clinical studies indicate that creatine may play a substantial role in diet-induced thermogenesis and may have a profound effect on energy balance.
- Trial name
- CreaBAT (NCT04086381)
- Testing
- Creatine monohydrate
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Obesity, Normal Physiology
The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure
Background: Diet-induced thermogenesis (DIT) is the amount of energy one's body uses to eat food, absorb the nutrients from the food, and process those nutrients.
- Conditions
- Obesity, Normal Physiology, Healthy Volunteers
- Trial name
- NCT05545306
- Testing
- +200% of dietary requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat, fasting, -50% of energy balance requirements. 50% of calories from carbohydrates, 20% from protein, and 30% from fat
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)