Clinical trials: Diet Modification
Body Weight Changes
The Effects of Formula Diet on Body Weight, Body Composition, and Biomarkers for Disease Compared to a Standard Diet
It is hypothesized that the use of a partial supplement diet, which includes the use of meal replacements, will result in significantly greater weight loss after three and six months compared to an isocaloric diet that does not…
- Trial name
- FORMULA (NCT00138645)
- Testing
- MicroDiet, Healthy Diet
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Type 2 Diabetes
High-amylose Barley (HIAMBA) in the Regulation and Prevention of Type 2 Diabetes
In a series of double-blinded randomized cross-over acute studies, the investigators want to study the effects of naturally produced high-amylose barley (Lean-baking barley®) on the postprandial glucose-metabolism in subjects…
- Trial name
- NCT04702672
- Testing
- 100% wheat (control), 100% Lean-baking barley®, 100% regular barley
- Where
- Denmark
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Insulin Resistance, Healthy
Dynamic Connectivity Under Metabolic Constraints
In this study, we investigate the impact of insulin resistance on the acceleration of brain aging, and test whether increased neuron insulin resistance can be counteracted by utilization of alternate metabolic pathways (e.g.…
- Conditions
- Insulin Resistance, Healthy, Diet Modification, Aging
- Trial name
- NCT04840095
- Testing
- Ketones, Glucose
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Nutrition Intervention, Healthy Eating
Improving Dietary Quality Through Animal Source Protein Accessibility in a Low-Resource Setting
Dietary quality is the lowest in the lifespan during childhood through adolescents, a period of rapid growth and development. Protein food recommendations and requirements for protein as a nutrient, along with other nutrients…
- Conditions
- Nutrition Intervention, Healthy Eating, Diet, Healthy, Hunger
- Trial name
- NCT07620028
- Testing
- Nutrition Secure Indianapolis Food Box Intervention, Nutrition Secure Indianapolis Nutrition Education
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Purdue University
Dietary Modification
Exercise Substrate Utilisation and Endurance Performance Following Short-term Manipulation of Dietary Fat Intake
The capacity to burn fat as fuel for exercise may have important implications for sporting performance, with dietary fat intake positively influencing this ability.
- Trial name
- NCT02568592
- Testing
- High Fat, Normal, Normal + Extra Fat
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Overweight
Effects of Acute Dietary Changes on Estimates of Body Composition
The present study sought to investigate the effects of acute dietary changes on estimates of body composition. Specifically, the impact of an acute high-carbohydrate diet (9 g/kg body weight of carbohydrate) and an acute very…
- Trial name
- NCT02888405
- Testing
- High-carbohydrate diet, Low-carbohydrate diet
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Baylor University
Cardiovascular Disease, Diabetes
Diet and Activity Promotion Among Older Working Adults
The trial will test whether the Alive email-delivered health behavior program can improve subjects' physical activity, fruits and vegetables and saturated/trans fats and added sugars.
- Conditions
- Cardiovascular Disease, Diabetes, Obesity, Aging
- Trial name
- ALIVE (NCT01233063)
- Testing
- Physical Activity and Diet Intervention via Alive2
- Where
- United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Berkeley Analytics, Inc.
Overweight and Obesity, Weight Loss
Personalized Obesity Management - Matching Dietary Fibers and Microbial Enterotype
The overall aim of this 12-week randomized controlled trial is to investigate if a dietary fiber supplement rich in arabinoxylans (AX) affects weight loss success differently according to baseline gut microbiota composition in…
- Trial name
- POMFAME (NCT05260762)
- Testing
- Arabinoxylan, Control
- Where
- Denmark
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Asthma, Dietary Intervention
Vegan Diet and Immune-Inflammatory Outcomes in Asthma and Healthy Adults
This randomized controlled study evaluates the effects of a balanced vegan diet compared with a balanced omnivorous diet on inflammatory and immune response markers and clinical asthma parameters in healthy adults and individuals…
- Conditions
- Asthma, Dietary Intervention, Vegan Diet
- Trial name
- VEGASTHMA (NCT07480369)
- Testing
- Omnivorous diet, Vegan diet
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Body Weight Changes, Mammographic Density
Impact of Diet and Physical Activity Changes on Body Weight, Biomarkers and Quality of Life in Breast Cancer Survivors
This study is a randomized controlled clinical trial of two arms, which included 60 women survivors of breast cancer of the state of Sonora, Mexico.The intervention is for 8 months and includes home visits every 15 days for the…
- Conditions
- Body Weight Changes, Mammographic Density, Quality of Life
- Trial name
- NCT04096469
- Testing
- Motivational Interviewing, Traditional Education
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centro de Investigación en Alimentación y Desarrollo A.C.
Inflammation, Smoking Cessation
Screening and Multiple Intervention on Lung Epidemics
This prospective randomized pilot trial will evaluate a multiple intervention program of prevention in lifelong smokers aiming at reduction of chronic inflammation status through treatment with low-dose acetylsalicylic acid…
- Conditions
- Inflammation, Smoking Cessation, Diet Modification, Physical Activity
- Trial name
- SMILE (NCT03654105)
- Testing
- Cytisine, Acetylsalicylic acid, Diet Modification and Physical Activity Increase
- Where
- Italy
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Non-alcoholic Fatty Liver Disease
Prebiotic Fibre Supplementation and Gut Microbiota in Non-alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease (NAFLD) is a condition where accumulation of fat in the liver leads to metabolic dysfunction. Currently there are no approved treatments for NAFLD.
- Trial name
- NCT02568605
- Testing
- Prebiotic fibre, Weight Loss
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Obesity
High Fat - High Protein Diet in the Treatment of Obesity
The purpose of this study is to examine the effects of a low calorie high fat/protein diet on body fat and body composition in overweight and obese subjects.
- Trial name
- NCT00299273
- Testing
- Low calorie high fat/protein diet
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Cardiovascular Disease
Mussel Intake and Vitamin D Status in Humans
A significant proportion of the United Kingdom population have inadequate levels of vitamin D in their blood. Vitamin D is a fat-soluble vitamin that is essential for the growth and maintenance of healthy bones through increasing…
- Trial name
- Mussel (NCT02982525)
- Testing
- No Mussels, One mussel portion, Two mussel portions
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Dietary Modification, Diet Habit
Supplementation of a Leucine-enriched Protein Blend
It is well known that dietary protein transiently stimulates muscle protein synthesis (MPS) whereby changes in MPS in response to feeding may be regulated by specific downstream target proteins of mammalian target of rapamycin…
- Trial name
- NCT03796897
- Testing
- Leucine-enriched protein, Habitual diet only
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- McMaster University
Obesity
Dietary Fiber: Is it the Missing Link in Achieving Long Term Behavior Change?
The overall objective of this three-arm randomized controlled trial is to compare a dietary fiber-focused behavioral intervention to standard weight loss education for improving eating-related behavior and cognition, weight, and…
- Trial name
- NCT06227494
- Testing
- Fiber Intervention, Standard Weight Loss Education
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Change in Dietary Outcomes
Improving Nutritional Outcomes Among Food Insecure Twin Cities Residents
This is a pilot intervention study conducted in four food shelves in the Twin Cities area. The aims of the study are to improve nutritional outcomes and client skills and self-efficacy among a culturally diverse group of food…
- Trial name
- NCT01983891
- Testing
- Cooking course
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Low Birthweight, Stunting
Impact of Benazir Nashonuma Program (BNP) on Maternal and Child Nutritional Status
The purpose of this study is to evaluate the impact of Benazir Nashonuma Program (BNP) which includes specialized nutritious food (SNF) augmented with specific reproductive health interventions during pregnancy on proportion of…
- Conditions
- Low Birthweight, Stunting, Wasting, Malnutrition, Child
- Trial name
- NCT05836961
- Testing
- Benazir Nashonuma Program (BNP)
- Where
- Pakistan
- Volunteers
- 5,500 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Postprandial Hyperglycemia, Metabolic Disorder, Glucose
Westlake N-of-1 Trials for Macronutrient Intake 2 ( WE-MACNUTR 2)
Diet and nutrition are key to maintain human health. Westlake N-of-1 Trials for Macronutrient Intake (WE-MACNUTR) trial investigates individualized postprandial glycemic responses to different proportions of dietary fat and…
- Trial name
- NCT05161182
- Testing
- High fat, low carbohydrate diet, Low fat, high carbohydrate diet
- Where
- China
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Westlake University
Gestational Weight Gain, Diet, Healthy
Implementation of a Mediterranean Diet Program for Overweight or Obese Pregnant Women in a Low-resource Clinical Setting
The purpose of this Pilot randomized clinical Trial is to compare two healthy diet styles during pregnancy. Patients between 8 and 16 weeks of gestation who agree to participate will be randomly assigned (like flipping a coin) to…
- Trial name
- MedDiet (NCT05868954)
- Testing
- MedDiet Program, ACOG-based Dietary Program
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences