Clinical trials: Dietary Fibre
Pre-diabetes
Impact of High Fiber and Vegetal Protein Diet on Gut Health and Immunity Biomarkers in Prediabetic Patients
The research area that focuses on the links between nutrition and health, nutrition and the immune system as well as nutrition-related public health interventions, which often falls into the gap between the agricultural and…
- Trial name
- PreVegDiet (NCT06147323)
- Testing
- Normal Healthy Diet, Seaweed Group
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Healthy Volunteers
Effect of Three Fibres on Glycaemic and Insulinaemic Responses in Healthy Adult Volunteers
The purpose of this study is to determine whether DuPont Experimental Dietary Fibre products 1 and 2 are digested using glycaemic and insulinaemic response as markers.
- Trial name
- NCT02701270
- Testing
- Experimental Dietary Fibre 1, Experimental Dietary Fibre 2, Polydextrose
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Danisco
Dietary Fibers, Intermediate Fasting
The Role of the Microbiome in the Response to Dietary Fibers Intake During Intermittent Fasting
Dietary fibers are generally not degraded by the endogenous digestive enzymes, but rather by the complex ensemble of microorganisms that reside in the human gut [1].
- Trial name
- NCT04633369
- Testing
- dietary fibers, Intermediate fasting
- Where
- Israel
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Weizmann Institute of Science
Dysbiosis, Cardiometabolic Health Indicators
Pulse Education and Children
This parallel-arm, randomized controlled trial will evaluate the effectiveness of a 6-week pulse-focused nutrition intervention in school-aged children (6-13 years).
- Conditions
- Dysbiosis, Cardiometabolic Health Indicators, Education on Feeding and Health Status, Gut Motility
- Trial name
- NCT07648446
- Testing
- Education Only, Education + Pulse Provision, Cooking Class
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Florida State University
Dental Restoration Failure
Clinical Performance of Polyethylene Fiber Reinforced Resin Composite Restorations (Wall Papering Technique) Versus Bulk Fill Resin Composite Restorations in Endodontically Treated Teeth Will be Evaluated Using Modified USPHS Criteria.
The aim of this study will be to evaluate the clinical performance of polyethylene fiber reinforced resin composite restorations versus bulk fill resin composite restorations in endodontically treated teeth.
- Trial name
- NCT05180903
- Testing
- X-tra base & GrandioSO reinforced by Ribbond
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy
The Effect of Functional Dairy Products Enriched With Dietary Fibers on Human Health and Gut Microbiota
The purpose of this dietary intervention is to study the effects of dietary fibers on the gut microbiota and use yoghurt as the carrier. Hypothesis 1: Intake of dietary fibers improves the blood lipid profile of the participants.
- Trial name
- NCT04811157
- Testing
- Test product, Control product
- Where
- Estonia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Center of Food and Fermentation Technologies
Occlual Caries, Proximal Caries
Clinical Evaluation of Self-Adhesive Bulk-Fil Hybrid Composite in Primary Molars
This study will evaluate the clinical performance of self-adhesive bulk-fill composite resin in the restoration of occlusal and occluso-proximal lesions in primary molars with hypothesis that there is no difference in the…
- Trial name
- NCT06724939
- Testing
- self-adhesive bulk-fill resin composite
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Caries
A Clinical Evaluation of a Glass Ionomer Cement (GIC) Based Restorative System Versus Bulk Filled Resin-based Composite
The aim of the present study is to evaluate the clinical performance of EQUİA restoration material in Class II cavities comparing with a resin-based composite / dentin bonding system.
- Trial name
- NCT02479711
- Testing
- composite restoration, glass ionomer cement
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ege University
Healthy
Effect of Prebiotic Intake on Gut Microbiota in Healthy Adults
In recent years, the importance of the gut microbiota to human health has been demonstrated. In adulthood, the microbial profile is relatively stable, yet can be transiently altered by factors such as diet or antibiotic…
- Trial name
- NCT03042494
- Testing
- Control, Prebiotic
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Metabolic Syndrome X
Comparison of Two Different Diets on Health Outcomes
The purpose of this study is to compare the effects of a low-carbohydrate diet and a high-carbohydrate, high-fiber diet, on insulin sensitivity and blood chemicals considered risk markers for heart disease, in persons with the…
- Trial name
- NCT00269646
- Testing
- Low-carbohydrate and high-carbohydrate diets
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Overweight, Obesity
Dietary Fibre and Chromium Picolinate Efficacy in Overweight and Obese Women
Obesity is one of the greatest causes of preventable morbidity and mortality worldwide with the main treatments requiring significant changes to lifestyle, particularly dieting and physical exercise.
- Trial name
- DFCP (NCT04250831)
- Testing
- agglomerated glucomannan, oligofructose and chromium mixture
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Intestinal Health
Fiber Fermentation Study
The aim of the study is to better understand the interplay between the intake of dietary fiber and intestinal bacteria, their metabolic activity and the effect on the intestinal barrier.
- Trial name
- NCT04570137
- Testing
- Dietary fiber supplementation
- Where
- Germany
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Restoration, Caries; Dentin
Composite Restorations in Primary Molars
The aim of this study was to compare the clinical performance of direct restorations with two different indirect composite systems in primary teeth.
- Conditions
- Restoration, Caries; Dentin, Caries Class Ii
- Trial name
- Composite Rest (NCT07761897)
- Testing
- Fédération Dentaire Internationale (FDI) criteria., survival comparison
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Prostate Cancer (Adenocarcinoma)
Understanding the Benefits of Dietary Fibre Supplementation in Patients With Prostate Cancer
The digestive tract (large intestine) contains microorganisms that digest complex carbohydrates in food to produce chemical substances which are beneficial to human health.
- Trial name
- EVENTIDE (NCT06661044)
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Insulin Resistance
Effects of Hi-maize Resistant Starch on Insulin Sensitivity
The purpose of this study is to determine the effects of a dietary fiber, resistant starch, on insulin sensitivity. Low insulin sensitivity is a risk factor for some diseases including type 2 diabetes and heart disease.
- Trial name
- NCT01058135
- Testing
- Hi-maize starch (Low dose), Hi-maize starch (High-dose), Control (starch)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ingredion Incorporated
Functional Constipation
Dose-ranging Efficacy of Polydextrose Supplement on Colonic Transit Time and Symptoms in Adults With Functional Constipation
This study will investigate the effectiveness of Polydextrose, a dietary fiber, at decreasing Colonic Transit Time and the gastrointestinal symptoms of Functional Constipation.
- Trial name
- NCT02314936
- Testing
- Litesse powder containing 12 g polydextrose, Litesse powder containing 8 g polydextrose, Litesse powder containing 4 g polydextrose
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Class I Dental Caries
CLINICAL COMPARISON OF DIFFERENT GLASS IONOMER-BASED RESTORATIVES AND A BULK-FILL RESIN COMPOSITE IN CLASS I CAVITIES: A 48-MONTH RANDOMIZED SPLIT-MOUTH CONTROLLED TRIAL
The aim of this study is to compare the clinical performances of high-viscosity glass ionomer (GI), glass carbomer (GC), zirconia-reinforced GI (ZIR), and bulk-fill (BF) composite resin restorations.For this purpose, two…
- Trial name
- NCT05559333
- Testing
- class I restoration placement
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy Adults
Resistant Starch and Satiety
Dietary fiber consumption may contribute to weight regulation by improving satiety. In an earlier study the investigators found that a muffin containing resistant starch was more effective than other fibers in altering satiety.
- Trial name
- NCT01187875
- Testing
- Hi-maize resistant starch 9g, Novalose 330 resistant starch 9g, 4.5g Hi-maize resistant starch and 4.5g Novalose 330
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Digestive Health, Quality of Life
Protein-Prebiotic Wellbeing Study
Healthy participants with self-reported GI complaints will consume the protein supplement that they normally use for recovery purposes after exercise during a 3-week baseline period, followed by a 3-week intervention period in…
- Trial name
- NCT05303753
- Testing
- fermented dairy protein with prebiotic fiber
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Constipation, Gastrointestinal Dysfunction
Effect of Polydextrose on Fecal Bulk and Bowel Function in Mildly Constipated Subjects
Polydextrose (PDX) (8-30g/day) has been reported to increase faecal bulk and consistency, leading to easier stool passage in healthy subjects.
- Trial name
- NCT05309837
- Testing
- Polydextrose
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Tate & Lyle