Clinical trials: Dietary Modification
Dietary Assessment, Dietary and Lifestyle Behaviour Change
BRE-13: Mediterranean Diet
Explore the effect of MedDiet vs. Usual Diet on circulating and breast tumor fatty acid profiles. The investigators aim to examine impact on tumor biology in newly diagnosed participants.
- Conditions
- Dietary Assessment, Dietary and Lifestyle Behaviour Change, Dietary Behavior, Metabolic Health
- Trial name
- BRE-13 (NCT07869355)
- Testing
- Explore the effect of MedDiet vs. Usual Diet on Fatty Acid Profile, Explore the effect of MedDiet vs. Usual Diet on Breast Tumor Tissue, Explore the effect of MedDiet vs. Usual Diet on Lipids
- Volunteers
- 30 people
- Sponsor
- University of Illinois at Chicago
Dietary Behavior; Metabolic Health; Obesity; Lifestyle Modification; Metabolic Syndrome Risk
Agentic AI Personalized Dietary Management Study
This randomized controlled trial aims to evaluate the effectiveness of an Agentic AI-based personalized dietary management algorithm among adults undergoing health screening.
- Trial name
- AIDiet (NCT07638241)
- Testing
- Static AI-based personalized dietary goal setting, Adaptive AI-based personalized dietary management
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Prostate Cancer, Prostatic Neoplasm
Dietary Fibre Supplementation to Delay Disease Progression in Early Prostate Cancer
This qualitative research study, based on semi-structured interviews and a focus group, aims to explore the attitudes of prostate cancer patients on active surveillance (AS) towards dietary fibre supplementation, given the…
- Conditions
- Prostate Cancer, Prostatic Neoplasm, Dietary Fibre Modification, Active Surveillance
- Trial name
- DEFINITE (NCT07790003)
- Testing
- Qualitative semi-structured interviews, Focus group
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Aberdeen
Dietary Modification, Cardiovascular Risk Factor
Gut Flora Metabolite Reduction After Dietary Intervention (GRADY)
Our group has recently identified the association between gut-flora-mediated carnitine and phosphatidylcholine metabolism, specifically trimethylamine-N-oxide (TMAO), and cardiovascular risk.
- Trial name
- GRADY (NCT02016430)
- Testing
- MeLT Dietary intervention, TLC Dietary intervention, MeLT dietary intervention with TMAO
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Type 2 Diabetes Mellitus (T2DM), Continuous Glucose Measurement
Comparison of Dietetics Support With and Without Continuous Glucose Monitoring in Individuals With Type 2 Diabetes.
A parallel, single-blinded, randomised clinical trial conducted remotely across Australia from the Mary MacKillop Institute for Health Research (MMIHR, Australian Catholic University) for individuals with type 2 diabetes, by…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Continuous Glucose Measurement, Dietary Modification
- Trial name
- CARE-T2D (NCT06888687)
- Testing
- Dietetic support, Continuous glucose monitoring
- Where
- Australia
- Volunteers
- 160 people
- Sponsor
- Australian Catholic University
Obese Adolescents, Exercise
Study of the Effect of Capsinoid Supplementation on Brown Adipose Tissue in Obese Adolescents
Among the new strategies being considered for the treatment of obesity and its metabolic complications, the activation of brown adipose tissue (BAT) from white adipose tissue looks promising.
- Conditions
- Obese Adolescents, Exercise, Diet Modification, Dietary Supplement
- Trial name
- ADOBAT (NCT06916208)
- Testing
- capsinoid supplementation
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University of Avignon
Parkinson Disease, Intestinal Bacteria Flora Disturbance
Resistant Maltodextrin for Gut Microbiome in Parkinson's Disease: Safety and Tolerability Study
This study will evaluate the safety and tolerability of a dietary fiber, resistant maltodextrin, in people with Parkinson's disease.
- Conditions
- Parkinson Disease, Intestinal Bacteria Flora Disturbance, Dietary Modification
- Trial name
- NCT03667404
- Testing
- Resistant maltodextrin, maltodextrin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Dietary Modification
CARNIVAL Study: Gut Flora Dependent Metabolism of Dietary CARNItine and Phosphatidylcholine and cardioVAscuLar Disease
The principal goal for the study is to examine the role gut flora plays in modulating metabolism of dietary carnitine and choline in humans.
- Trial name
- CARNIVAL (NCT01731236)
- Testing
- Carnitine, Choline, Antibiotics
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Constipation, Constipation - Functional
Soluble and Osmotic Fibre (SOLOS) Diet for Constipation
This research aims to study the dual effectiveness of incorporating soluble fibre and osmotic carbohydrates (SOLOS), with or without restricting fructans and GOS, and present novel findings in managing GI symptoms in patients…
- Conditions
- Constipation, Constipation - Functional, Constipation Chronic Idiopathic, Constipation Predominant Irritable Bowel Syndrome
- Trial name
- SOLOS (NCT07388589)
- Testing
- Diet
- Where
- Singapore
- Volunteers
- 180 people
- Sponsor
- Singapore Institute of Technology
Spinal Cord Injuries, Metabolic Syndrome
Spinal Cord Injury Exercise and Nutrition Conceptual Engagement
Evaluate and compare the health benefits of an at home exercise program using functional electrical stimulation (FES) for lower extremity exercise with diet versus a diet alone group in adults with spinal cord injury.
- Conditions
- Spinal Cord Injuries, Metabolic Syndrome, Dietary Modification, Paraplegia
- Trial name
- SCIENCE (NCT03495986)
- Testing
- Functional Electrical Stimulation Leg Cycle Ergometry, Diet
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Miami
Diabetes, Gestational, Dietary Modification
Dietary Management of Gestational Diabetes
eMOM is a randomized, controlled trial to compare the effects of two different dietary interventions during pregnancy. The comparison is based on tissue glucose content (using continuous glucose monitoring system) in pregnant…
- Conditions
- Diabetes, Gestational, Dietary Modification, Glucose Intolerance During Pregnancy, Body Composition
- Trial name
- eMOM (NCT03681054)
- Testing
- Carbohydrate restricted diet, Plant-protein based diet
- Where
- Finland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Metabolic Response to Dietary Modification
The CLOCK Study - A Human Dietary Intervention Study on Peripheral Circadian Clocks and Energy Metabolism
This human dietary intervention study with a cross-over design aims to investigate the effect of two different diurnal patterns of meal composition on peripheral circadian clocks and energy metabolism in healthy men.
- Trial name
- CLOCK (NCT02487576)
- Testing
- Carbohydrate-rich (HC), Fat-rich (HF)
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- German Institute of Human Nutrition
Dyspepsia, Dietary Modification
Study to Evaluate Dietary Modification in Patients With Functional Dyspepsia.
The purpose of this study is to evaluate the effectiveness of the low fermentable oligo-di-monosaccharides and polyols (FODMAP) diet in functional dyspepsia (FD).
- Trial name
- NCT02863822
- Testing
- Low FODMAP Diet, Choose My Plate Diet
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Physical Therapy, Electrotherapy
Electroacupoint for Diminutive Milk Production
The purpose of this study was to reveal the effect of electroacupoint on scanty milk production in lactating women.
- Conditions
- Physical Therapy, Electrotherapy, Dietary Modification
- Trial name
- NCT06590805
- Testing
- Electrotherapy using Chattanooga stimulation unit, Balanced Diet using domperidone drug, iron, and folic acid supplementation.
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Haytham Ibrahim Morsi
Dietary Modification, Diet Habit
Supplementation of a Leucine-enriched Protein Blend
It is well known that dietary protein transiently stimulates muscle protein synthesis (MPS) whereby changes in MPS in response to feeding may be regulated by specific downstream target proteins of mammalian target of rapamycin…
- Trial name
- NCT03796897
- Testing
- Leucine-enriched protein, Habitual diet only
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- McMaster University
Multimodal Intervention, Fragility
Effectiveness of a Multi-component Physical Training in Hyper-fragile Elders: A Randomized Clinical Trial
Objective: To compare short-term and medium-term effectiveness of a multimodal program that integrates a program of therapeutic exercise, medication review, adequacy of diet and health education, compared with standard medical…
- Conditions
- Multimodal Intervention, Fragility, Other Metabolic Diseases, Physical Activity
- Trial name
- PowerA-01 (NCT02772952)
- Testing
- Control Intervention, Multimodal Intervention
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Obesity, Weight Loss
Utilizing Protein During Weight Loss to Impact Physical Function and Bone
This study is an ancillary study to the Utilizing Protein During Weight Loss to Impact Physical Function (UPLIFT) trial (NCT03074643) to evaluate the effects of diet composition (i.e., amount of protein and carbohydrate) during a…
- Conditions
- Obesity, Weight Loss, Diet Modification, Aging
- Trial name
- UPLIFT-Bone (NCT03819478)
- Testing
- Weight loss intervention months 0-6, Exercise intervention months 0-6, NutraBio™ CarboMax Supplement
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Wake Forest University Health Sciences
Dietary Modification, Cardiovascular Diseases
Oral Carnitine Challenge Test Guides Personalized Nutrition for CV Patients
The investigators plan to use the recently developed oral carnitine challenge test (OCCT) as a tool to exam individual's trimethylamine N-oxide (TMAO) production capacity from their gut microbiota.
- Trial name
- NCT03781011
- Testing
- Vegetarian diet intervention
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Dietary Modification
The Impact of a Powdered Meal Replacement on Metabolism and Gut Microbiota
This study will investigate the impact of a 12-week powdered meal replacement on inflammatory, metabolic, and hormonal markers of obesity-associated conditions and to correlate this response to compositional shifts within the gut…
- Trial name
- PREMIUM (NCT03235804)
- Testing
- Soy protein, honey and yogurt.
- Where
- Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Childhood Obesity, Excessive Weight Gain in Pregnancy With Baby Delivered
Preventing Childhood Obesity: A Two-pronged Approach Starting in Pregnancy and the First Year Postpartum
Our longitudinal aim is to reduce childhood obesity using our two-pronged intervention program, which includes healthy food choices and increased physical activity initiated during pregnancy and re-instated in the early period…
- Conditions
- Childhood Obesity, Excessive Weight Gain in Pregnancy With Baby Delivered, Dietary Modification, Healthy Lifestyle Habits
- Trial name
- NCT01129505
- Testing
- Nutrition & Exercise Lifestyle Intervention Program (NELIP)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Western University, Canada