Clinical trials: Dietary Modifications
Healthy
Bioavailability and Vascular Effects of Apple Polyphenols
The main purpose of this study is to determine the oral bioavailability of flavanols (polyphenolic compounds) from apple granules and an apple extract delivered in a water based beverage at two different doses.
- Trial name
- POLYMALUS (NCT01097226)
- Testing
- Apple extract delivering 70 mg epicatechin, Apple extract delivering 140 mg epicatechin, Apple granules delivering 70 mg epicatechin
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Adolescent Behavior, Nutrition, Healthy
Advanced Cooking Education Feasibility Study
The aim of this study is to look at outcomes related to diet and nutrition, mindfulness, and cooking skills amongst middle school students who participated in a 12-week 4-H after school program called the Advanced Cooking…
- Trial name
- NCT05907278
- Testing
- Advanced Cooking Education
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Cornell University
Overweight, Diabetes
Effect of Nutritional Interventions on Inflammatory Status in Healthy Overweight Men
In the present study it is hypothesized that a reduction of the inflammatory status may prevent the occurrence of disorders and diseases related to overweight.
- Conditions
- Overweight, Diabetes, Cardiovascular Disease
- Trial name
- NCT00655798
- Testing
- Plain Yogurt + mix of anti-oxidants capsules, Yogurt containing Lactobacillus helveticus, Yogurt containing Bifidobacterium animalis ssp.
- Where
- Netherlands
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- TNO
Dietary Intervention, Gut Microbiota
Phenolic Dependent And Independent Effects Of Whole Grain Sorghum On Immunometabolism
Sorghum is a nutrient-dense ancient grain that, when eaten as a whole grain, provides health-beneficial dietary fiber, protein, and phenolics.
- Conditions
- Dietary Intervention, Gut Microbiota, Insulin Sensitivity/Resistance, Obesity & Overweight
- Trial name
- NCT07832071
- Testing
- Whole grain sumac sorghum, Whole grain white sorghum, White rice
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Diet Modification
The Influence of the Microbiome on the Pharmacokinetics of Flavan-3-ols
Cocoa beans are of major interest due to their various beneficial health effects, indicated to be caused by its cocoa flavan-3-ols. (-)-Epicatechin is the most abundant flavan-3-ol in these cocoa beans.
- Trial name
- PhTI (NCT05113498)
- Testing
- (-)-Epicatechin
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Ghent
Oxidative Stress
Effect of Red Raspberry Consumption on Fasting Oxidative Stress Biomarkers
The purpose of this study is determine whether daily consumption of frozen red raspberries can improve the antioxidant capacity of the blood and reduce the effects of oxidative stress, dose-dependently, in a healthy adult…
- Trial name
- NCT00876811
- Testing
- individually quick frozen red raspberries
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Overweight and/or Obesity, Children - Malnutrition
Family-Based Nutrition Intervention to Prevent Overweight and Obesity in School-Age Children.
This proposal aims to enhance the well being of schoolchildren and their families through a mobile application and multidisciplinary intervention model grounded in authoritative parenting principles and social cognitive theory.
- Conditions
- Overweight and/or Obesity, Children - Malnutrition, Preventing Malnutrition
- Trial name
- NCT07159971
- Testing
- School B, Control
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Claudia Teresa Tovar Palacio
Cardiovascular Disease
Effect of Apple Flavanols on Risk of Cardiovascular Disease
A randomised three period cross over trial will be carried out in adults (19-64 years) to assess the acute and chronic effects of a large dose of apple procyanidin (PA) compared with a low dose of apple PA (negative control) and…
- Trial name
- FLAVO (NCT00568152)
- Testing
- Low PA apple puree, High PA apple puree, Aspirin
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Dietary Habits
Dietary Intervention to Mitigate Adverse Consequences of Night Work
The goal of this clinical trial is to test whether our dietary intervention can prevent or lessen the negative health effects of night shift work in healthy participants.
- Trial name
- NCT04868526
- Testing
- dietary intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obesity (Disorder), Morbid Obesity
Chrono-ALIGN: A Chronotype-Based Chrono-Nutrition Intervention in Post-Bariatric Patients
This randomized controlled trial will evaluate the impact of chrono-nutrition, a dietary approach that aligns meal timing with the body's circadian rhythms, on weight change, metabolic outcomes, appetite, and gut microbiota in…
- Conditions
- Obesity (Disorder), Morbid Obesity, Bariatric Sleeve Gastrectomy, Meal Time
- Trial name
- Chrono-ALIGN (NCT07324044)
- Testing
- Standard Post-Bariatric Care (Control), Early Time-Restricted Eating (eTRE), Chronotype-Based Chrono-Nutrition (CB-CN)
- Where
- Saudi Arabia
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- King Saud University
Infectious Disease, Children, Only
Prebiotic Fructans on the Incidence of Acute Infectious Diseases in Children
The study aims to explore whether prophylactic dietary supplementation with prebiotic inulin-type fructans is able to influence the intestinal microbiota and the frequency of infectious disease episodes in kindergarten children…
- Conditions
- Infectious Disease, Children, Only, Diet Modification
- Trial name
- NCT03241355
- Testing
- prebiotic inulin-type fructan
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Beneo-Institute
Maternal Dietary Diversity, Iron-Folic Acid Supplementation
A Feasibility Study of Integrating Maternal Nutrition Interventions Into Antenatal Care Services in Ethiopia
Alive \& Thrive (A\&T) is an initiative that supports the scaling up of nutrition interventions to save lives, prevent illnesses, and contribute to healthy growth and development through improved maternal nutrition, breastfeeding…
- Conditions
- Maternal Dietary Diversity, Iron-Folic Acid Supplementation, Early Initiation of Breastfeeding
- Trial name
- NCT04125368
- Testing
- Health Facility Interventions, Community Interventions, Health System Interventions
- Where
- United States
- Volunteers
- 4,256 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Chronic Kidney Diseases, Cardiovascular Diseases
Cardiorenal Protective Diet
This study will evaluate providing fruits and vegetables in a sustainable community care clinic setting, in addition to routine medical care, to individuals with CKD (Stage 2-4) on CKD and CVD risk, or cardio-renal risk factors.
- Conditions
- Chronic Kidney Diseases, Cardiovascular Diseases, Hypertension
- Trial name
- CPD (NCT04117204)
- Testing
- Fruits and Vegetables
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Weight Loss, Postpartum Weight Retention
Weight Loss and Physical Fitness Following Pregnancy in Active Duty Women
Pregnancy and delivery are major stressors on the female body and contribute significantly to permanent weight gain and associated morbidity in women.
- Trial name
- PADaWL (NCT05518604)
- Testing
- Counseling with goal of modifying eating behaviors
- Where
- 2 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Tripler Army Medical Center
Metabolic Syndrome
The Effect of Dietary Fat Modification on Risk Factors Associated With the Metabolic Syndrome
The LIPGENE Human Dietary Intervention Study, multi-centre, trans -European, single-blinded, randomised, controlled trial with two principal aims.
- Trial name
- NCT00429195
- Testing
- Dietary Fatty Acid Modification
- Where
- Ireland
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Consumer Behavior, Food Selection
Process and Effect Evaluation of the Project "Aan Tafel in 1,2,3 Euro"
The goal of this research project is to learn what the impact of the specific project "Aan Tafel in 1 2 3 euro" is on the food and meal habits of families of lower SES.
- Trial name
- NCT05595551
- Testing
- The intervention "Aan Tafel in 1, 2, 3 euro"
- Where
- Belgium
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- University Ghent
Dietary Modification, BRCA1 Mutation
Dietary Intervention and BRCA Penetrance
Insulin-like growth factor I (IGF-I) and other markers of insulin resistance (IRm) might modulate the penetrance of BRCA genes mutation.
- Conditions
- Dietary Modification, BRCA1 Mutation, BRCA2 Mutation, Breast Cancer
- Trial name
- NCT03066856
- Testing
- Dietary intervention
- Where
- Italy
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Gestational Diabetes Mellitus
Improving Cardio-metabolic and Mental Health in Women With Gestational Diabetes Mellitus and Their Offspring
MySweetHeart Trial is a randomized controlled trial to test the effect of a multidimensional interdisciplinary lifestyle and psychosocial intervention to improve the cardio-metabolic and mental health of women with GDM and their…
- Trial name
- MySweetHeart (NCT02890693)
- Testing
- interdisciplinary lifestyle and psychosocial intervention
- Where
- Switzerland
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Healthy
The Role of Synbiotics in Modulating Host Physiology Via the Gut Microbiome
The current study is a proof of concept mechanistic study that will utilise a combination of prebiotic and probiotic (synbiotic) supplements.
- Trial name
- NCT06480812
- Testing
- Synbiotic
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Elizabeth Simpson
Dietary Modification, Diet Habit
Supplementation of a Leucine-enriched Protein Blend
It is well known that dietary protein transiently stimulates muscle protein synthesis (MPS) whereby changes in MPS in response to feeding may be regulated by specific downstream target proteins of mammalian target of rapamycin…
- Trial name
- NCT03796897
- Testing
- Leucine-enriched protein, Habitual diet only
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- McMaster University