Clinical trials: Dietary Proteins
Inflammation, Malnutrition
Effect of Anti-inflammatory Diet on Inflammatory, Oxidative and Nutritional Markers in Hemodialysis Patients
The purpose of this study is to evaluate the effect of especial diet therapy "Anti-inflammatory Diet" on inflammatory, oxidative stress, and nutritional markers in the context of protein-energy wasting syndrome(PEW) in…
- Conditions
- Inflammation, Malnutrition, Protein Energy Wasting Syndrome, Oxidative Stress
- Trial name
- NCT01874106
- Testing
- Diet Therapy, Control Group
- Where
- Iran
- Volunteers
- 120 people
- Sponsor
- Maryam Ekramzadeh, PhD
Prediabetes, Type-2 Diabetes
Dietary Intervention Replacing Carbohydrate With Protein and Fat Has Greater Effect on Peripheral Blood Mononuclear Cell Metabolites Than on Plasma Metabolites in Patients With Prediabetes or Type-2 Diabetes
This study examined whether dietary-induced reductions in lipoprotein-associated phospholipase A2 (Lp-PLA2) activity in peripheral blood mononuclear cells (PBMC) and plasma affected metabolic profiles in PBMCs and plasma.
- Trial name
- NCT02191644
- Testing
- Dietary intervention-refined rice, Dietary intervention-whole grains and legumes
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- Yonsei University
Obese Adolescent, Elite Adolescent Athletes
Effect of the Quality of Dietary Proteins on the Sleep Young Elite Athletes and the Obese Adolescent
Adolescence is characterized by major transitions in sleep and circadian rhythm. This rapid pivotal period increases the risks of sleep debt and poor sleep quality, leading to pronounced diurnal fatigue and drowsiness .
- Trial name
- Protmorpheus (NCT04041934)
- Testing
- tryptophan
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Clermont-Ferrand
Obesity, Diet Modification
Anthropometric Parameters, Metabolic Profile and Function of the Respiratory System in Obese Patients
Obesity is currently considered an increasingly more severe social and health related problem. The World Health Organization qualified obesity as a chronic disease along with circulatory diseases, diabetes, cancer and respiratory…
- Conditions
- Obesity, Diet Modification, Physical Activity
- Trial name
- NCT03346421
- Testing
- diet and physical activity
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Poznan University of Medical Sciences
Breast Cancer
The Potential for Oral Diindolylmethane (DIM) Supplementation to Increase the Production of the BRCA1 Protein in BRCA1 Mutation Carriers
Women with a BRCA1 mutation face a lifetime risk of breast cancer of approximately 70% and a lifetime risk of ovarian cancer of approximately 40%.
- Trial name
- NCT01022333
- Testing
- Diindolylmethane (DIM)
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Dietary Intervention, Dietary Proteins
Investigating the Effects of Beef Consumption on Cognitive and Brain Health
The goal of this clinical trial is to learn if eating more beef will lead to better cognition and a healthier brain in younger adults.
- Conditions
- Dietary Intervention, Dietary Proteins, Dietary Assessment, Cognitive Ability, General
- Trial name
- NCT06690892
- Testing
- Ready-to-eat beef in frozen, 5-oz packages, Ready-to-eat beef in frozen, 1-oz packages
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Heat Stress, Diet Induced Thermogenesis
Carbohydrate or Protein Drinks Before Exercise in the Heat
This project examines whether consuming a high-protein or high-carbohydrate beverage before exercise in the heat impacts metabolism and heat balance during exercise, with the following research questions: 1.
- Conditions
- Heat Stress, Diet Induced Thermogenesis, Protein Consumption
- Trial name
- NCT07646990
- Testing
- Protein shake, Carbohydrate shake
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Providence College
Type 2 Diabetes Mellitus
Metabolic Activation With Protein-rich Formula Diet
Formerly, the investigators demonstrated in an uncontrolled proof-of principle study (NCT 01680926) that protein-rich meal replacement (PRMR) was successful in reducing daily insulin demand, HbA1c and weight in type 2 diabetes…
- Trial name
- AVS (NCT02230501)
- Testing
- stringent diet regimen, moderate diet regimen
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- West German Center of Diabetes and Health
Insulin Resistance
Study of Keto Acid (KA) on Insulin Resistance in Peritoneal Dialysis (PD) Patients
The overarching aim of this proposal is to examine the effects of usual protein diet supplemented with keto acid (KA) on insulin sensitivity in patients on peritoneal dialysis (PD).
- Trial name
- NCT01496092
- Testing
- Keto Acid
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University First Hospital
Diet, Healthy
Red Palm Olein on Inflammation and Gut Health
A parallel intervention was conducted to test the effect of consuming diets enriched with red palm olein (RPOO), extra virgin coconut oil (EVCO) and extra virgin olive oil (EVOO; positive control) in centrally obese individuals…
- Trial name
- RPO (NCT05791370)
- Testing
- A 12-week parallel dietary intervention
- Where
- Malaysia
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Dietary Protein Intake
App-based Protein Support for Older Adults; Coaching Towards Healthy Ageing
Rationale: Sufficient dietary protein intake helps to preserve muscle mass and strength and is a key factor in healthy ageing. Achieving an increased protein intake with regular food products has shown to be a challenge for many…
- Trial name
- APPROACH (NCT07415408)
- Testing
- Nutritional coaching via an app, Exercise recommendations
- Where
- Netherlands
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Dietary Fats, Carbohydrates
Macronutrients and Postprandial Vascular Function
Vascular function decreases following the intake of a mixed meal in some, but not all studies. Differences in the relative amounts of dietary fat, carbohydrates and protein present in the mixed-meal challenges may have…
- Conditions
- Dietary Fats, Carbohydrates, Proteins, Macronutrients
- Trial name
- NCT03139890
- Testing
- High-fat (HF-LC-LP) milkshake, High-carbohydrate (LF-HC-LP) milkshake, High-protein (LF-LC-HP) milkshake
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Weight Loss, Starvation
Effect of Caloric Restriction and Protein Intake on Metabolism and Anabolic Sensitivity
The purpose of this study is to determine if an increased protein intake can attenuate the suppression of metabolic and anabolic hormones during caloric restriction
- Trial name
- NCT02945410
- Testing
- Caloric Restriction, Protein, Exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Overweight (BMI > 25), Obesity & Overweight
WB-EMS Combined With Nutritional Guidance for a High-Protein Diet on Body Composition, Muscle Function, Psychological and Functional Outcomes in Older Adults With Excess Adiposity
This is a 16-week randomized controlled trial (RCT) with outcome assessor blinding. The objective is to investigate the effects of resistance training (RT) combined with whole-body neuromuscular electrical stimulation (WB-NMES)…
- Conditions
- Overweight (BMI > 25), Obesity & Overweight, Aging
- Trial name
- WB-EMS (NCT07859072)
- Testing
- Whole-Body Neuromuscular Electrical Stimulation (WB-NMES), Conventional Resistance Training, High-Protein Nutritional Guidance
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Universidade Cesumar (UNICESUMAR)
Multiple Myeloma (MM), CAR T Cells
BEAM-MM - β-Hydroxybutyrate-Enhanced Adaptive Immunity in Multiple Myeloma
This study investigates whether raising blood levels of beta-hydroxybutyrate (BHB) - a natural molecule produced by the body during fasting or a low-carbohydrate diet - is safe and feasible and can improve the effectiveness of…
- Conditions
- Multiple Myeloma (MM), CAR T Cells, Bispecific Antibodies
- Trial name
- BEAM-MM (NCT07564219)
- Testing
- Ketogenic diet, Ketogenic Drinks
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Phenylketonurias
Life With Phenylketonuria. Adult Neurological Outcome of PCU Screened Patients From 1971 to 2002.
You were detected during the neonatal period for phenylketonuria and you benefited from the diagnosis of an adapted dietetic care, and this for a variable duration according to the recommendations followed at that time.
- Trial name
- PCU (NCT04433728)
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Lille
Liver Transplantation, Metabolic Syndrome X
Mediterranean Diet and Protein-Sparing Modified Diet for Metabolic Syndrome in Liver Transplant Recipients
Many metabolic complications can develop after liver transplant including: diabetes, high blood pressure, obesity, heart attacks and stroke.
- Conditions
- Liver Transplantation, Metabolic Syndrome X, Obesity
- Trial name
- NCT02174783
- Testing
- Control group, Mediterranean diet, Protein-Sparing Modified Fast (PSMF)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The Cleveland Clinic
Old Age; Cachexia, Dietary Habits
The Nutritionist's Educational Intervention on the Protein Intake in Hospitalized Elderly People
The food intake is often compromised in the elderly, and during hospitalization, dietary restrictions may be imposed, making them more susceptible to the risk of malnutrition and sarcopenia.
- Conditions
- Old Age; Cachexia, Dietary Habits, Sarcopenia, Protein Malnutrition
- Trial name
- NCT05502445
- Testing
- educational intervention
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- Hospital Israelita Albert Einstein
Muscle Protein Synthetic Response to Protein, Muscle Protein Synthesis
Diet Synergy in Muscle Protein Synthesis
In the present semi-crossover randomized design, 15 recreationally active young adults (19-40 y) will receive stable isotope tracer infusions and perform a single bout of resistance exercise.
- Conditions
- Muscle Protein Synthetic Response to Protein, Muscle Protein Synthesis, Muscle Health, Protein Metabolism
- Trial name
- POTATO (NCT07367854)
- Testing
- Resistance Exercise, Potato and Beef, Bread and Beef
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Healthy
Improving Dietary Protein Intake in Adults
A pilot, single-arm investigation used coaching, nutrition education, and a per-meal protein prescription to assess impact on protein intake, muscle strength and function in older adults.
- Trial name
- NCT04378556
- Testing
- Nutritional coaching
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Florida Atlantic University