Clinical trials: Dietary Selenium Deficiency
Selenium Deficiency
Optimization of Selenoprotein P in Chinese Subjects
The purpose of this study is to determine the amount of selenium as selenomethionine that is required to optimize selenoprotein P in selenium-deficient Chinese subjects
- Trial name
- NCT00428649
- Testing
- 20 µg selenium, 40 µg selenium, 60 µg selenium
- Where
- China
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
HIV Infections, Substance-Related Disorders
The Effects of Nutritional Supplementation and Drug Abuse on HIV
The purpose of this trial is to determine whether supplementation with multivitamins and selenium will delay disease progression in HIV infected individuals in Botswana.
- Trial name
- NCT00149656
- Testing
- Multivitamins, Selenium
- Where
- Botswana
- Volunteers
- 878 people
- Sponsor
- Florida International University
Iodine Excess in Pregnancy, Selenium Excess in Pregnancy
The Correlation Between Iodine and Selenium Status in Pregnancy and Risk of Thyroid Disease
Two hundred and ninety pregnant women with gestational age less than 20 weeks will be recruited in this study. Selenium and iodine conditions, and risk of thyroid disease will be monitored until termination of pregnancy, with…
- Conditions
- Iodine Excess in Pregnancy, Selenium Excess in Pregnancy, Iodine Deficiency in Pregnancy, Selenium Deficiency in Pregnancy
- Trial name
- NCT03761602
- Testing
- Not applicable (for observational studies)
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Rongrong Li
HIV
Rwanda Selenium Supplementation Clinical Trial
Study Hypothesis: The addition of selenium supplementation to cotrimoxazole will improve CD4 counts, decrease opportunistic infections, decrease viral loads and delay the need for initiating antiretroviral therapy(ART) in Rwandan…
- Trial name
- RSST (NCT01327755)
- Testing
- Selenium
- Where
- 2 sites in Rwanda
- Volunteers
- 300 people
- Sponsor
- The Canadian College of Naturopathic Medicine
Endothelial Dysfunction, Regulation of Acute Inflammatory Response
Endothelial Dysfunction and Selenium Status in Children With Acute Systemic Inflammatory Response
The overall hypotheses of this project is that severe sepsis is associated with endothelial dysfunction in pediatric patients and that selenium deficiency is associated with changes in biological markers of endothelial…
- Conditions
- Endothelial Dysfunction, Regulation of Acute Inflammatory Response, Selenium Deficiency
- Trial name
- NCT02619344
- Where
- Brazil
- Volunteers
- 114 people
- Sponsor
- Federal University of São Paulo
Pregnancy, Thyroid Autoimmune Disease
Potential Preventive Effect of Selenium on Iodine-induced Thyroid Autoimmunity During Pregnancy
In 1994, the WHO and UNICEF Joint Committee on Health Policy recommended Universal Salt Iodization as a safe, cost-effective and sustainable strategy to ensure sufficient intake of iodine by all individuals.
- Conditions
- Pregnancy, Thyroid Autoimmune Disease, Iodine Deficiency, Selenium Deficiency
- Trial name
- NCT03377218
- Testing
- Iodine, Iodine + Selenium
- Where
- Latvia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Riga Stradins University
Critical Illness, Nutritional Deficiency
Trace Element Repletion Following Severe Burn Injury
Major burn patients are characterized by large exudative losses of Cu, Se and Zn. Trace element (TE) repletion has been shown to improve clinical outcome.
- Conditions
- Critical Illness, Nutritional Deficiency, Trace Element Deficiency, Burn Injury
- Trial name
- NCT03204669
- Testing
- Trace elements replacement
- Where
- Switzerland
- Volunteers
- 139 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
HIV Infection
Correlation of HIV Levels With Clinical and Immunologic Outcome in Children Treated With Didanosine
Recent studies have shown that patients receiving state-of-the-art treatment for HIV infection (highly active antiretroviral therapy, or HAART) show discordant responses to therapy-that is, they improve both clinically and…
- Trial name
- NCT00026676
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- National Cancer Institute (NCI)
Dietary Selenium Deficiency, Dietary Zinc Deficiency
Zinc and Selenium Supplementation in Atherosclerosis
The aim of this randomized double-blind study was to evaluate the effect of oral zinc and selenium supplementation on oxidative stress and inflammation biomarkers as well as the status of zinc and selenium in patients with…
- Trial name
- NCT01547377
- Testing
- zinc and selenium supplementation
- Where
- Brazil
- Volunteers
- 76 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Type 2 Diabetes
Different Diets in Different Diabetes - 4DI PLAN'EAT Pilot Study
The goal of this clinical trial is to learn whether a diet adapted to a person's cultural background, combined with a supervised physical activity programme, improves blood sugar control better than standard dietary advice in…
- Trial name
- 4DI PLAN'EAT (NCT07887477)
- Testing
- Culturally adapted Mediterranean diet, Supervised walking programme, Standard dietary and behavioural counselling
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- University of Bologna
Selenium Deficiency, Thyroid Cancer TNM Staging
Clinical Study on the Effect of Selenium Yeast Capsule on Prognosis of Differentiated Thyroid Carcinoma
Oxidative stress is involved in the pathogenesis of thyroid cancer, but the mechanism is not clear. The thyroid is the organ with the most abundant selenium content, and selenium may be involved in protecting the gland from the…
- Conditions
- Selenium Deficiency, Thyroid Cancer TNM Staging, Recurrence, Metastasis
- Trial name
- NCT04683575
- Testing
- Selenium Yeast
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Qianfoshan Hospital
Immunity, Vaccine Reaction
Efficacy and Tolerability of ABBC1 in Volunteers Receiving the Influenza or Covid-19 Vaccine
The immune system response needs to be forceful but also balanced for a rapid recovery from infection which avoids harmful overreactions.
- Conditions
- Immunity, Vaccine Reaction, Influenza, Covid19
- Trial name
- NCT04798677
- Testing
- ABBC1 Immunoessential
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- AB Biotek
Selenium Deficiency
Prospective, Non-randomized Observational Trial of Selenium in Cardiac Surgery
In this observational study the effect of selenium supplementation on the postoperative inflammatory response and clinical course should be examined in (approximately 100) adult patients undergoing elective heart surgery combined…
- Trial name
- SICS (NCT01394068)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Cognitive Change, Nutrient Deficiency
Nutrition, Vision, and Cognition in Sport Study: Beef
The purpose of this study is to determine whether a 30 day beef intervention can improve peak cognitive performance in young, normally menstruating adult women.
- Conditions
- Cognitive Change, Nutrient Deficiency, Nutritional Anemia, Visual Spatial Processing
- Trial name
- IONSport:Beef (NCT04427852)
- Testing
- 30 day Daily consumption of 1 serving of beef, 30 day Daily consumption of 1 serving of the vegatable protein source
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Abdominal Aneurysm, Selenium Deficiency
Selenium Levels in Patients With Abdominal Aneurysm
Retrospective study comparing the selenium level in patients with abdominal aortic aneurysm with the selenium level in patients in the control group, i.e., patients without aneurysmal changes of the abdominal aorta.
- Trial name
- NCT07236281
- Where
- Slovakia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Comenius University
Critical Illness, Selenium Deficiency
The Prognostic Impact of Selenium On Critical Surgical Patients
Selenium is an important trace element for human for its multiple roles such as the antioxidant activity. Previous evidences showed that critically ill patients may benefit from selenium supplement but the dose and results are…
- Conditions
- Critical Illness, Selenium Deficiency, Trace Element Deficiency, Acute Abdomen
- Trial name
- NCT04662242
- Testing
- Selenium Supplement, normal saline
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Chang Gung Memorial Hospital
HIV, ART
Effect of Zinc and Selenium Supplementation on HIV+ Individuals on Antiretroviral Treatment.
The aim of this study is to evaluate the effect of zinc gluconate and/or selenium yeast supplementation during six months on clinical (glucose, cholesterol, triglycerides, bone mineral density and body composition) and…
- Conditions
- HIV, ART, Zinc Deficiency, Selenium Deficiency
- Trial name
- NCT03421314
- Testing
- Zinc gluconate and/or Selenium yeast
- Where
- Mexico
- Volunteers
- 37 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
Selenium Deficiency
Research on Association Between Selenium Deficiencies and Change of Thyroid Function
As one of the essential micronutrients, selenium has important biological functions. However, an effective and convenient method for evaluation of selenium nutritional status has not yet been established.
- Trial name
- NCT03448588
- Testing
- detection of serum selenium
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Selenium Deficiency
Correction of Selenium Deficiency Has Effect on Thyroid Function
Previous literature has found potential association between selenium deficiency and inactivated glutathione peroxidase and deiodinase, which may contribute to subsequent elevation of T4 and ratio of T4/T3.
- Trial name
- NCT03445078
- Testing
- selenium supplementation, ordinary corn powder
- Volunteers
- 20 people
- Sponsor
- Peking Union Medical College Hospital
HIV Infections, Pregnancy Complications
Partnership on Nutrition and HIV/AIDS Research in Tanzania: Exploratory Research Study on Selenium and HIV Infection
The purpose of this study is to determine whether the oral administration of daily selenium supplements to HIV-1 positive pregnant women: enhances immune status and reduces the HIV-1 viral load at six months postpartum, reduces…
- Trial name
- NCT00197561
- Testing
- Selenium
- Where
- Tanzania
- Volunteers
- 915 people
- Sponsor
- Harvard School of Public Health (HSPH)