Clinical trials: Dietary Supplementation
Hyperlipidemias, Hypercholesterolemia
Supplementation of Oil Palm Phenolics to Improve Lipid Profile in Subjects With Minor Hyperlipidaemia
An unpublished study by the investigators on healthy participants has shown that the supplementation of oil palm phenolics (OPP) at 250 mg is the optimum dose to demonstrate the ability to lower total and LDL cholesterol.
- Trial name
- NCT04573218
- Testing
- 250 mg OPP
- Where
- Malaysia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Isa Naina Mohamed
Heart Failure, Acidosis, Lactic
Preoperative Parenteral Thiamine Supplementation in Patients Undergoing Heart Surgery
The objective of this study is to determine whether preoperative parenteral thiamin supplementation does prevent the intra and early postoperative increase of lactate and whether this effect is related to the extent of thiamine…
- Conditions
- Heart Failure, Acidosis, Lactic, Thiamine Deficiency
- Trial name
- NCT01524315
- Testing
- Vitamin B1-ratiopharm
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Early Pregnancy
Vitamin B12 Supplementation to Improve B12 Status and Child Development
Impaired vitamin B12 (B12) status during pregnancy is associated with increased risk of birth defects and common complications (e.g. intrauterine growth restriction, neural tube defects), and possibly immune function impairment.
- Trial name
- NCT03258385
- Testing
- Vitamin B12 fortified UHT milk, Plain UHT milk
- Where
- Bangladesh
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Long COVID, Cardiorespiratory Fitness
Nitrite Supplementation in Long COVID Patients
Potential benefits of a nitrate-rich juice supplement to improve skeletal muscle function and associated physical capacity will be studied in patients with Long COVID.
- Trial name
- NCT05618574
- Testing
- 140 ml per day of Beet-It nitrate beverage (James White Drinks Ltd., Ipswich, UK)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
Systemic Lupus Erythematosus
The Effect of Vitamin D Supplementation on Disease Activity Markers in Systemic Lupus Erythematosus (SLE)
Systemic lupus erythematosus (SLE) is a chronic multi-system inflammatory autoimmune disease. Vitamin D has potent immunomodulatory properties that have promoted its potential use in the treatment of autoimmune conditions…
- Trial name
- NCT01425775
- Testing
- vitamin D 25(OH)D
- Where
- Egypt
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- University of Alexandria
Infertility
Comparison of Crinone 8% Intravaginal Gel and IM Progesterone Supplementation for In Vitro Fertilization (IVF)
The goal of this research study is to compare the pregnancy rates for two different types of progesterone supplementation after in-vitro fertilization (IVF).
- Trial name
- NCT00656201
- Testing
- Crinone 8% Vaginal Gel, Intramuscular Progesterone
- Where
- United States
- Volunteers
- 468 people
- Sponsor
- Brigham and Women's Hospital
Autoimmune Diseases
Personalized Management of Autoimmune Diseases With AI-Guided (GenAIS TM) Dietary Supplementation
The study "Personalized Management of Autoimmune Diseases with AI-Guided (GenAIS TM) Dietary Supplementation" investigated the effectiveness of AI-guided dietary supplement (DS) prescriptions compared to standard physician-guided…
- Trial name
- NCT06470412
- Testing
- Control group, AI-Guided Group
- Where
- Russia
- Volunteers
- 160 people
- Sponsor
- S.LAB (SOLOWAYS)
Inflammation; Muscle, Iron Metabolism
The Effect of Supplementation of Vitamin D3 on Inflammation Induced by 100 km Running, Iron Metabolism and Erythropoiesis
A group of runners received vitamin D (10,000 IU - international unit per day) for two weeks. The aim of the intervention was to check the effect of vitamin D supplementation on selected parameters of inflammation and iron…
- Conditions
- Inflammation; Muscle, Iron Metabolism, Ineffective Erythropoiesis, Healthy
- Trial name
- NCT05880030
- Testing
- Cholecalciferol
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Nutrition, Sports
Effects of Sulforaphane Supplementation on Athletic Performance
Considering the promising effects observed and the scarce and incipient scientific background of SFN in sports, the present study aims to evaluate the effects of SFN supplementation on fatigue, EIMD and recovery in trained…
- Trial name
- NCT07343518
- Testing
- Fatigue protocol
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Maia
Pseudoxanthoma Elasticum
PPI Supplementation to Fight ECtopIc Calcification in PXE
Pseudoxanthoma elasticum (PXE) is a rare inherited metabolic disorder (OMIM 264800, frequency 1/25000) characterized by progressive ectopic calcification of connective tissues.
- Trial name
- PROPHECI-PPI (NCT04868578)
- Testing
- study treatment PPI
- Where
- 2 sites in France
- Volunteers
- 99 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Athletic Performance
Effect of Beetroot Nitrates on Different Physical Skills in Colombian Rugby Athletes
Beetroot is a source of nitrates, which have demonstrated various positive effects in sports, with little evidence in intermittent sports such as ball sports (including rugby).
- Trial name
- NCT07106489
- Testing
- 40 meters sprint, Fitness test by bronco test, Maximal strength
- Where
- Colombia
- Volunteers
- 10 people
- Sponsor
- Universidad Nacional de Colombia
Aging
Geriatric Recovery Using Inpatient and Post-hospitalization Supplementation
The purpose of the study is to determine the feasibility of nutritional interventions designed to help older patients maintain physical function after being in the hospital.
- Trial name
- GRIPS (NCT03904615)
- Testing
- Whey Protein, Collagen Protein
- Where
- 2 sites in United States
- Volunteers
- 116 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Ulcerative Colitis (UC)
Oral Vitamin D3 Effect on Inflammatory Biomarkers in Ulcerative Colitis Patients
This randomized controlled trial aims to evaluate the effect of oral vitamin D3 supplementation on inflammatory biomarkers and disease activity in Pakistani patients with moderate ulcerative colitis.
- Trial name
- OVDIEIBUCP (NCT07269223)
- Testing
- Vitamin D3
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Diabetes Mellitus, Type 1
Effects of Micronutrient (Chromium) Supplementation on Diabetes
6-8% of USA population has diabetes. Intensive blood glucose control dramatically reduces the devastating complications that result from poorly controlled diabetes.
- Trial name
- NCT01709123
- Testing
- chromium niacinate
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Arterial Stiffness, Vitamin K2 Deficiency
Vitamin K2 Supplementation and Arterial Stiffness in the Renal Transplant Population (The KING Trial)
This study is a single arm, single center clinical trial that aims to evaluate the effect of 8 weeks of vitamin K2 replacement (360 mcg/day) on the progression of arterial stiffness in stable renal transplant patients.
- Trial name
- KING (NCT02517580)
- Testing
- Vitamin K2 (MK7)
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Lebanese American University
Focus on Omega 3 Index on Recovery
Long-Term Omega-3 and Omega-3 Index >8%: Effects on Physiological Recovery
The Omega-3 Index measures how much of the Omega-3 fats EPA and DHA are built into red blood cell membranes. These fats are essential for health, but the body cannot make enough of them, so they must come from foods like oily…
- Trial name
- IMPROVE-8 (NCT07439601)
- Testing
- Oil Supplementation
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Pregnant Women
Comparison of The Effect of 5-MTHF and Folic Acid Supplementation in Increasing Red Blood Cell Folate in Pregnant Women
This randomized controlled trial aims to compare the efficacy of 5-methyltetrahydrofolate (5-MTHF) and folic acid supplementation in increasing red blood cell (RBC) folate levels in pregnant women.
- Trial name
- NCT06935630
- Testing
- Folic Acid, 5-MTHF (5-methyltetrahydrofolate)
- Where
- Indonesia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Dr. Soetomo General Hospital
Age Related Macular Degeneration
Macula Evolution in Patients With AMD Taking Oral Food Supplementation
LT7082-001 is an open-label, single-arm pilot study. Patients with intermediate age-related macular degeneration (AMD) wil take T7082 during 12 months , an association of 4 food supplementations .
- Trial name
- NCT04778436
- Testing
- T7082
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Laboratoires Thea
Microbiota, Supplementation
L. Reuteri SGL 01 in Nursing Mothers: Effects on Milk Microbiota and Neonatal Gut Colonization
The Reuteri17 study is a spontaneous, prospective, randomized intervention study designed to evaluate the effects of maternal supplementation with the probiotic Lactobacillus reuteri SGL 01 on the composition of the breast milk…
- Conditions
- Microbiota, Supplementation, Breastfeeding
- Trial name
- Reuteri17 (NCT07404930)
- Testing
- probiotic Lactobacillus reuteri SGL 01
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Social Exclusion, Chronic Disease
Protocol for a Low Threshold Exercise Intervention for Women Experiencing Homelessness and Addiction.
Background: Frailty is a complex multi-dimensional state of increased vulnerability to adverse health outcomes and is usually associated with older age but there is growing evidence of accelerated ageing and frailty in…
- Conditions
- Social Exclusion, Chronic Disease, Physical Disability, Addiction
- Trial name
- LEAP-W (NCT06264895)
- Testing
- Exercise
- Where
- Ireland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
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