Clinical trials: Dietary Zinc Deficiency
Zinc Deficiency, Diarrhea
Water-based Zinc Intervention Trial in Zinc Deficient Children
The overall aim of this trial is to determine whether the use of the household-based water treatment device Life Straw Family (LSF) can be an effective strategy to improve zinc status and health status of vulnerable populations…
- Trial name
- NCT01472211
- Testing
- zinc enriching filter (LifeStrawFamily), disinfection tablets
- Where
- Benin
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Very Low Birth Weight Infant, Nutritional Deficiency
Enteral Zinc Supplementation in Very Low Birth Weight Infants
The goal of this clinical trial is to observe for changes in rate of weight gain in the very low birth weight (VLBW) infants by adding an enteral Zinc supplement of 1 mg/kg/day of elemental zinc.
- Trial name
- NCT06433674
- Testing
- Zinc Sulfate, Sterile Water
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Zinc Deficiency, Mother and Child Malnutrition
Multi-Omic Profiling of a Zinc-Biofortified Maize Intervention in Guatemalan Mothers and Children
A trial evaluating the systemic and ecological impact of zinc-biofortified maize consumption on cellular zinc status, inflammatory biomarkers, and gut microbiota composition in a cohort of Guatemalan mothers and children.
- Trial name
- NCT07585318
- Testing
- F3 Biofortified Maize, Conventional Maize
- Where
- Guatemala
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition of Central America and Panama
Iron-deficiency, Vitamin A Deficiency
Sub Regional Micronutrient Survey in Ethiopia
To conduct a sub-regional micronutrient survey (SRMNS) assessing the prevalence of vitamin A, Zn, and Fe status in the country
- Conditions
- Iron-deficiency, Vitamin A Deficiency, Zinc Deficiency
- Trial name
- NCT03353662
- Testing
- Women of Gamo Gofa, Children of Gamo Gofa, Women of West Gojjam
- Where
- 2 sites in Ethiopia, Switzerland
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
HIV Infections
Evaluating the Safety and Pharmacokinetics of PC-1005 Administered Rectally to HIV-1 Seronegative Adults
The purpose of this study is to evaluate the safety and pharmacokinetics of PC-1005 gel when used as a rectal microbicide in HIV-uninfected men and women (cis or transgender) with a history of consensual receptive anal…
- Trial name
- NCT03408899
- Testing
- PC-1005 gel
- Where
- 2 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Zinc Deficiency
Effects of Initiation and Discontinuation of Short Term Zinc Supplementation on Plasma Zinc Concentration
This is a double-blind, randomized controlled trial conducted in men 19-65 years of age who will receive daily zinc supplements (10 or 20 mg zinc/d as zinc sulfate) or placebo for 21 days.
- Trial name
- NCT00459485
- Testing
- zinc sulfate
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Fluoride Poisoning, Hemoglobin
Using Eggshell Calcium to Mitigate Fluorosis in Ethiopia
Mothers and young children in rural Ethiopia lack sufficient nutrition, and a compounding factor is presence of high levels of fluoride (> 5-10 mg/day) affecting body functions.
- Conditions
- Fluoride Poisoning, Hemoglobin, Underweight, Stunting
- Trial name
- NCT03355222
- Testing
- Promotion of chicken eggs
- Where
- Ethiopia
- Volunteers
- 270 people
- Sponsor
- University of Saskatchewan
Iron Deficiency Anemia
Comparison of Ferrous Sulfate, Polymaltose Complex and Iron-zinc in Iron Deficiency Anemia
The aim of the present study was to compare the effectiveness of the different oral iron preparations in children with IDA.
- Trial name
- NCT02076828
- Testing
- Ferro Sanol® sp, Santafer® sp., Ferro Zinc® sp
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Zinc Deficiency
Efficacy of Zn Biofortified Wheat in Improving Zn Status in Indian School Children With Low Zn Status
The objective of this research is to test the efficacy of Zn biofortified wheat in increasing Zn status in Indian school children aged 6-12 y via a 6 month randomized controlled trial.
- Trial name
- NCT02241330
- Testing
- Biofortified wheat, Fortification, Control
- Where
- India
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Individuals at Risk of Zinc Deficiency
Zinc Absorption From SQ-LNS With and Without Phytase
Background: Community based-intervention trials conducted among infants and young children in low- and middle-income countries have found that zinc supplementation of young children (in the form of liquid supplements or…
- Trial name
- NCT02668133
- Testing
- the nutritional supplement to be used in this trial is a SQ-LNS, lipid-based nutrient supplement (SQ-LNS) with phytase, 0.9 mg isotopically enriched 67Zn,0.30 mg isotopically enriched 70Zn, 0.60 mg non-enriched zinc
- Where
- The Gambia
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Very Preterm Infants, Zinc Deficiency
Higher and Standard Doses of Enteral Zinc Supplementation in Very Preterm Infants
The goal of this randomized clinical trial is to compare the effect of higher (10 mg per day) versus standard (1 mg per day) doses of zinc supplementation The main questions it aims to answer are: Growth velocities and delta…
- Trial name
- ZnVeryPT (NCT06219525)
- Testing
- Higher dose of enteral zinc, Standard dose of enteral zinc
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Prince of Songkla University
HIV Infection, HIV Infections
Phase 1 Dose Escalation Study of Autologous T-cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Patients
This research study is being carried out to study a new way to possibly treat HIV. This agent is called a "Zinc Finger Nuclease" or ZFN for short. ZFNs are proteins that can delete another protein named CCR5.
- Trial name
- NCT01044654
- Testing
- SB-728-T
- Where
- 9 sites in United States
- Volunteers
- 19 people
- Sponsor
- Sangamo Therapeutics
Zinc Deficiency, Inflammation
Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc
The objective of the current study is to test the overarching hypothesis that the beef nutritive matrix is uniquely suited to direct dietary zinc to cellular compartments for improved metabolic function, leading to a greater…
- Conditions
- Zinc Deficiency, Inflammation, Metabolic Diseases, Vascular Diseases
- Trial name
- NCT05236374
- Testing
- Beef protein
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Autism Spectrum Disorder, Zinc Deficiency
Zinc-AA Supplementation During Pregnancy & Lactation to Assess Effects on ASD Prevalence in Offspring
Autism and associated entities, grouped under the Autism Spectrum Disorders (ASD) is the fastest growing intellectual disability in the world, statistics signal for a 1 to 3% prevalence on infants.
- Conditions
- Autism Spectrum Disorder, Zinc Deficiency, Pregnancy Related
- Trial name
- NCT04983667
- Testing
- Zn-AA
- Where
- Mexico
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Instituto Tecnologico y de Estudios Superiores de Monterey
Renal Insufficiency, Chronic, Zinc Deficiency
Correction of Zinc Deficiency in Children With Chronic Kidney Disease and Kidney Transplant
Children with chronic kidney disease, even after transplantation, may be at risk for bone problems due to an imbalance of calcium and phosphorus in the blood, especially as their kidneys progressively fail to function.
- Conditions
- Renal Insufficiency, Chronic, Zinc Deficiency, Trace Element Excess, Trace Element Deficiency
- Trial name
- NCT02126293
- Testing
- Zinc Supplement, Repeat blood and urine tests
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Hamilton Health Sciences Corporation
Inflammation, Cardiovascular Diseases
Zinc Effect on Inflammation and Cardiovascular Risk in HIV
To study the effect of short-term zinc supplementation on improving inflammation, metabolic, and cardiovascular risk among HIV infected patients on stable anti-retroviral therapy
- Conditions
- Inflammation, Cardiovascular Diseases, Zinc Deficiency
- Trial name
- NCT05085834
- Testing
- Zinc Gluconate
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- University Hospitals Cleveland Medical Center
Development, Iron Deficiency
Zinc, Iron, Vitamin A and Psychosocial Care for Child Growth and Development
Many Indonesian infants are already iron deficient before they reach the age of six months, which also determines the high prevalence of anemia among under-five children.
- Conditions
- Development, Iron Deficiency, Zinc Deficiency
- Trial name
- NCT02319499
- Testing
- Zinc Alone, Iron and Zinc, Iron, Zinc and Vitamin A
- Where
- Indonesia
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Zinc Deficiency
Zinc Intervention in Elderly for Prevention of Pneumonia
Pneumonia is a major public health problem for the elderly and is one of the leading causes of hospitalization and death for this population, particularly for elderly nursing home residents.
- Trial name
- ZIPP (NCT05527899)
- Testing
- Zinc gluconate
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Tufts University
Iron Deficiency
The Effect of Zinc on Iron Bioavailability From Fortified Extruded Rice Fortified With Ferric Pyrophosphate
Investigation of Iron Bioavailability from extruded rice grains fortified with Ferric Pyrophosphate alone or in combination with different Zinc Compounds; Ferrous Sulfate serves as a Reference.
- Trial name
- Rice_FeZn (NCT02255942)
- Testing
- Ferric Pyrophosphate and Zinc Oxide, Ferrous sulfate, Ferric Pyrophosphate and Zinc Sulfate
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Enteropathy
Zinc Resistant Starch Project
Broad - to examine the result of feeding RS to 3-5 year old rural Malawian children on zinc homeostasis and environmental enteropathy (EE). Specific - 1.
- Trial name
- NCT01811836
- Testing
- Zinc
- Where
- Malawi
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine