Clinical trials: Difference, Individual
Peripheral Arterial Disease, Intermittent Claudication
Motivating Structured Walking Activity in Intermittent Claudication
Peripheral arterial disease can cause leg pain or discomfort (called intermittent claudication (IC)), which limits the ability to walk and carry out everyday activities.
- Conditions
- Peripheral Arterial Disease, Intermittent Claudication, Peripheral Vascular Disease
- Trial name
- MOSAIC (NCT03238222)
- Testing
- MOSAIC
- Where
- 9 sites in United Kingdom
- Volunteers
- 192 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Obesity, Diabete Type 2
Digital Intervention Promoting Physical Activity Among Obese People (DIPPAO)
Overweight and obesity are today considered among the most important health risks facing humanity with more than one in two adults overweight or obese in western countries.
- Trial name
- DIPPAO (NCT04887077)
- Testing
- Kiplin, face-to-face
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Clermont-Ferrand
Multiple Sclerosis
How to Develop the Highest Possible Leading-edge Interdisciplinary Care Model for People With MS, That Will be Relevant to All Stakeholders and Declinable to Different Local Contexts With the Ultimate Goal of Ensuring the Highest Level of Quality of Care in MS.
Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating and degenerative disease of the central nervous system. It is currently not curable, although several disease-modifying treatments (DMT) reduce the occurrence of…
- Trial name
- MUSICALISE (NCT07289724)
- Testing
- Focus group, individual interview
- Where
- France
- Volunteers
- 57 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Solid Tumours
A Study to Test How Well Different Doses of BI 4060107 Are Tolerated by People With Advanced Cancer (Solid Tumours)
This study is open to adults with advanced cancer who have selected types of solid tumours that cannot be surgically removed. People can join the study if they have tried all available treatments and have no other options.
- Trial name
- NCT07827144
- Testing
- BI 4060107
- Where
- 6 sites in United States, Australia and 3 more
- Volunteers
- 86 people
- Sponsor
- AIMEDBIO
Prostate Cancer
Comparing Two Different Boost Approaches in Radiation Therapy for People With Prostate Cancer
In this study the investigators will find out whether the use of a new type of boost approach called irreversible electroporation (IRE) is as effective as the standard boost approach of radiation therapy for participants with…
- Trial name
- NCT07548164
- Testing
- NanoKnife System, Stereotactic Body Radiation Therapy
- Where
- 8 sites in United States
- Volunteers
- 224 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Haemophilia A
A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A
This study will test how different doses of study medicine (Inno8) work in the bodies of people with haemophilia A. The purpose of the study is to see if Inno8 is safe to use for people with haemophilia A.
- Trial name
- VOYAGER2 (NCT07220564)
- Testing
- NNC0442-0344 A
- Where
- 33 sites in United States, Austria and 10 more
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 2
A Research Study to Compare Two Different Versions of Injectable CagriSema in People With Type 2 Diabetes
This study is being done to look at how well a study medicine called CagriSema helps people with diabetes lower their blood sugar.
- Trial name
- NCT07357740
- Testing
- CagriSema
- Where
- 61 sites in United States, Denmark and 6 more
- Sponsor
- Novo Nordisk A/S
Metastatic Colorectal Cancer
A Real-World Study to Learn More About the Order of Different Treatments and Their Effects in People With Metastatic Colorectal Cancer Receiving Their Third and Fourth Line of Treatment
This is an observational study in which data already collected from people with metastatic colorectal cancer will be studied. Metastatic colorectal cancer (mCRC) is a cancer of the colon (large bowel) or the rectum (lowest part…
- Trial name
- RegoSeq (NCT06137170)
- Testing
- Regorafenib (Stivarga, BAY73-4506)
- Where
- 3 sites in France, Italy and 1 more
- Volunteers
- 121 people
- Sponsor
- Bayer
Parkinson Disease
Exercise and Sleep in Parkinson's Disease
This study will investigate the impact of two common exercise modalities, cardiovascular and resistance training, on sleep quality and architecture in persons with Parkinson's disease (PD), and whether these potential positive…
- Trial name
- NCT04558879
- Testing
- CT, RT
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McGill University
Differential Female Response to Δ9-tetrahydrocannabinol (THC)
Individual Differences in Drug Response
Females are increasingly using cannabis, yet remain underrepresented in preclinical and clinical cannabinoid research. This female-specific research plan will test the effects of two recreationally relevant doses of oral THC and…
- Trial name
- IDT (NCT03809546)
- Testing
- Dronabinol, dextrose
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Circadian Rhythm, Time Perception
Circadian Timing and Time Perception in Healthy Adults
This study examines how a person's natural daily rhythm ("chronotype") affects the way time is experienced and judged. Healthy Danish-speaking adults (23-45 years) who are clearly morning-type or evening-type will complete two…
- Trial name
- ChronoTime (NCT07292597)
- Testing
- Session timing relative to chronotype
- Where
- Denmark
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Healthy Control, Depression
Concurrent TMS-fMRI
The goal of this clinical trial is to examine the neural mechanisms underlying transcranial magnetic stimulation (TMS) using concurrent functional magnetic resonance imaging (fMRI) in both healthy controls (HCs) and patients with…
- Trial name
- NCT06633913
- Testing
- spTMS-TBS-spTMS
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Jing Jiang
Traumatic Brain Injury
The Environment's Impact on Thinking When Added to Leg Cycling in People With TBI: VITAL
Aerobic exercise is a promising treatment modality for cognition in persons with TBI, but effects are consistently small. This study aims to investigate the effect of difference environments during moderate intensity cycling…
- Trial name
- VITAL (NCT04901286)
- Testing
- Exercise Only, Exercise + Non-Immersive Virtual Reality, Exercise + Immersive Virtual Reality
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Kessler Foundation
Parkinson Disease
The Effects of Tele-rehabilitation Interventions in Parkinson's Patients
Parkinson's Disease (PD) is the most common neurodegenerative movement disorder. The main motor symptoms of PD are tremor, rigidity, bradykinesia, and postural instability.
- Trial name
- NCT05187195
- Testing
- Home-based telerehabilitation with exercise videos, Exercise brochure
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Istanbul University - Cerrahpasa
Hearing Loss, Tinnitus
Hearing Impairment, Cognitive Therapy and Coping
A randomized controlled study with hearing impaired workers, who have voluntarily signed up for an 8 session cognitive therapy (CBT) course The CBT intervention will be compared to a waiting list control group.
- Conditions
- Hearing Loss, Tinnitus, Stress, Psychological, Mental Fatigue
- Trial name
- NCT01206829
- Testing
- 8-session CBTcourse, 8 session cognitive behavioral therapy
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- Oslo University Hospital
COVID-19
Recombinant Omicron-Delta COVID-19 Vaccine (CHO Cell)
Popular topic:A Clinical Study of Recombinant Omicron-Delta COVID-19 Vaccine (CHO Cell) Overall design:The study was designed as a randomized, open and controlled study.
- Trial name
- NCT05574985
- Testing
- Recombinant Omicron-Delta COVID-19 Vaccine (CHO Cell), Inactivated COVID-19 vaccine (Vero Cell)
- Where
- China
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Sepsis, Prognostic Model
Artificial Intelligence Prognostic Model for Sepsis Based on Time Series Analysis
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. It is one of the leading causes of death and disability worldwide, with an inpatient mortality rate of 10-20%.
- Conditions
- Sepsis, Prognostic Model, Artificial Intelligence, Individuality
- Trial name
- NCT06724120
- Testing
- No interventions
- Where
- China
- Volunteers
- 3,641 people
- Sponsor
- West China Hospital
Neck Pain
Comparison Of Different Physiotherapy Methods In People With Non-Specific Neck Pain
The study will include 45 people between the ages of 25-55 with non-specific neck pain. The patients will be randomly divided into three groups.
- Trial name
- Pain (NCT07004491)
- Testing
- Conventional therapy, Conventional therapy+ Mulligan mobilization, Conventional therapy+ Graston
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Multiple Sclerosis
Internet-based Physical Activity Promotion and Exercise Prescription for People With Multiple Sclerosis
The aim of the study is to evaluate the effects of a 12-week internet-based exercise and physical activity promotion intervention on physical activity.
- Trial name
- ms bewegt (NCT04367389)
- Testing
- Physical activity promotion, Exercise
- Where
- 9 sites in Germany
- Volunteers
- 62 people
- Sponsor
- University of Erlangen-Nürnberg
Low Back Pain
A Trial on the Effect on Low Back Pain Related Disability of Different Health Education Programs for Retired Persons
The primary purpose of this study is to compare, in retired persons living in the Balearic Islands, the effectiveness on low back pain related disability of three educational programs.
- Trial name
- NCT00441038
- Testing
- The Back Guide, The Back Book, Cardiovascular and general health
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kovacs Foundation