Clinical trials: Diffusion-weighted MRI
Stroke, Software Verification, Diffusion Weighted MRI, Neuroimaging
Automated Volume Assessment of Acute Stroke
Stroke is a common disease. It is increasingly managed in non-specialized centers. The volume of the lesion, evaluated on the diffusion weighted imaging, is a prognostic factor of clinical progression and is useful for the…
- Trial name
- AVAAS (NCT03618251)
- Testing
- specific MRI sequences
- Where
- France
- Volunteers
- 406 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Gastro-enteropancreatic Neuroendocrine Tumor, Secondary Malignant Neoplasm of Liver
The Reproducibility Of Diffusion Weighted Magnetic Resonance Imaging For Neuroendocrine Tumor Liver Metastases
Imaging with CT (Computed Tomography) or MRI (Magnetic Resonance Imaging) is normally used to see how tumors respond to treatment. If tumors shrink after therapy, doctors continue with the same treatment.
- Trial name
- NCT01423734
- Testing
- magnetic resonance imaging (MRI)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cerebral Infarct, Neurological Morbidity
Evaluation of Cerebral Parenchymal Changes in Patients Undergoing Proximal Aortic Surgery With Deep Hypothermic Circulatory Arrest Using Diffusion MRI
Deep hypothermic circulatory arrest (DHCA) (18 degree) without cerebral perfusion is a safe technique. Resarchers use this technique in patients with proximal aortic pathologies.
- Conditions
- Cerebral Infarct, Neurological Morbidity, Neurological Complication
- Trial name
- NON (NCT04755439)
- Testing
- DHCA
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital
Urinary Bladder Neoplasm
Role of Diffusion -Weighted MRI in Evaluation of Urinary Bladder Masses
Urinary bladder cancer is a common malignant tumor of the urinary tract in both men and women. Proper management of the urinary bladder cancer depends on the stage of the lesions.
- Trial name
- NCT05097105
- Testing
- MRI
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Carpal Tunnel Syndrome, Neurodynamic Treatment
Mechanisms of Neurodynamic Treatments
INTRODUCTION: Carpal tunnel syndrome (CTS) is a relatively common condition caused by compression of one of the main nerves at the wrist, the median nerve.
- Conditions
- Carpal Tunnel Syndrome, Neurodynamic Treatment, Nerve Mobilisation, Diffusion MRI
- Trial name
- MONET (NCT05859412)
- Testing
- Neurodynamic exercises, Steroid injection (Depomedrone 40mg), Advice
- Where
- United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Thyroid Nodule
B-mode Ultrasound, Sono-Elastography, and Diffusion-weighted Imaging MRI in Thyroid Nodules
To compare the accuracy of the conventional Ultrasound 'TI-RADS', US elastography, DWI MRI, and its ADC value in characterization and differentiation of thyroid nodules.
- Trial name
- NCT06029946
- Testing
- elastography, ultrasound
- Volunteers
- 50 people
- Sponsor
- Assiut University
Lung Neoplasms
Application of Diffusion Weighted MRI Versus CT in Evaluation of the Effect of Treating Lung Cancer
The purpose of this study is to investigate the diagnostic accuracy of ADC value of diffusion weighted MRI in comparison of conventional treatment assessment criteria in evaluation of chemotherapy.
- Trial name
- NCT02320617
- Testing
- Diffusion Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Air Force Military Medical University, China
Multiple Sclerosis - Relapsing Remitting, Clinically Isolated Syndrome, CNS Demyelinating
DTI in Children With Multiple Sclerosis
This is a prospective, non-randomised, non-blinded, single center study of children and adolescents with multiple sclerosis and clinically isolated syndrome to detect differences or early changes in diffusion-weighted imaging…
- Trial name
- NCT02361697
- Testing
- DTI-MRI
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Patients With a Sonographically Unclassifiable Adnexal Mass Using the IOTA Simple Rules
Value of MRI in the Characterization of Ovarian Masses Unable to Classify With Ultrasound Using the International Ovarian Tumor Analysis (IOTA) Simple Rules
Gynecological ultrasound is well known as the preferred exam to assess patients with ovarian tumors. The International Ovarian Tumor Analysis (IOTA) group developed the 'Simple Rules' to classify an ovarian tumor as benign or…
- Trial name
- IOTA-MRI (NCT02836275)
- Testing
- Diffusion/Perfusion-weighted Magnetic Resonance Imaging
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- KU Leuven
Pelvic Diseases, Abdominal Diseases
The Study of Functional Magnetic Resonance Imaging in Abdominal and Pelvic Diseases
The purpose of this study is to study the diagnostic efficiency of functional magnetic resonance imaging in Abdominal and Pelvic Diseases.
- Trial name
- NCT02337777
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Cancer of the Uterine Cervix
Diagnostic Performance of 18F-FDG-PET and Diffusion-weighted MRI in the Assessment of Stage IB to IIB2 Cervical Squamous-cell Carcinoma Response to Concomitant Radiochemotherapy and Brachytherapy
Rationale: The benefit-risk ratio of surgery following concomitant radiochemotherapy and brachytherapy remains to be defined in cervical squamous-cell carcinoma (SCC) treatment.
- Trial name
- ERRICC (NCT01663753)
- Testing
- 18F-FDG-PET
- Where
- 24 sites in France
- Volunteers
- 146 people
- Sponsor
- Hospices Civils de Lyon
Huntington Disease
Accelerated Diffusion MRI for Diagnosis of Hungtington Disease
The hypotheses of the project are 1. Diffusion MRI using compressed sensing could have reduced motion sensitivity and improved susceptibility related artifact because of accelerated acquisition. 2.
- Trial name
- NCT01884181
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Wang . Jiun-Jie
Stroke
CHinese Acute Tissue-Based Imaging Selection for Lysis In Stroke -Tenecteplase II
To explore the efficacy and safety of tenecteplase for acute ischemic stroke patients (onset time 4.5-24h) of large vessel occlusion using early combined CT/MR imaging outcomes
- Trial name
- CHABLIS-T II (NCT04516993)
- Testing
- Tenecteplase, The best treatment selected by local doctors(Aspirin, Recombinant Tissue Plasminogen Activator, Urokinase, Thrombectomy)
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Huashan Hospital
Fibrosis, Liver
Diffusion-weighted Imaging Magnetic Resonance for Assessing Liver Fibrosis
Several noninvasive radiological techniques have been investigated for the diagnosis of liver fibrosis and cirrhosis among patients with chronic infection with hepatitis B virus or hepatitis C virus.
- Trial name
- NCT02682108
- Testing
- Diffusion-weighted magnetic resonance imaging (DW-MRI)
- Where
- Thailand
- Volunteers
- 121 people
- Sponsor
- Mahidol University
Cholesteatoma
Usefulness of Non EPI-DWI-MRI / CT 3D Static Co-registration Prior to Surgery of Cholesteatomas
Cholesteatoma is a destructive and expanding pathologic condition consisting of keratin pearl arising from a squamous epithelium in the middle ear and/or mastoid process.
- Trial name
- NCT02903550
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Crohn's Disease
Comparison of Endoscopy and Diffusion-weighted Enterography-MRI for the Diagnosis of Crohn's Disease Recurrence Following Ileocolic Resection: a Pilot Study
Nearly three-quarters of patients with Crohn's disease have small bowel involvement and 80% of them will have complications that will require a surgical procedure, usually an ileocolonic resection with ileocolonic anastomosis.
- Trial name
- MRI-CROHN (NCT02867540)
- Testing
- MRI enterography
- Where
- France
- Volunteers
- 40 people
- Sponsor
- CHU de Reims
Rectum Cancer, Pelvic Cancer
Assessment of DW-MRI Measures : Reproducibility and Repeatability in Pelvic Imaging on MR-Linac With Healthy Volunteers
This study evaluates the reliability of functional MRI measurements in pelvic disease through quantifying repeatability and reproducibility, using healthy volunteers.
- Trial name
- PILLAR (NCT06458725)
- Testing
- Magnetic Resonance Imaging (MRI)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute
Uterine Cervical Neoplasms
MRI (Including Spectroscopy and Fat-Saturations and Diffusion-Weighted Imaging) in Cervical Cancer
To detect differences in MR spectroscopy, diffusion weighted MR, diffusion tensor imaging (DTI) or dynamic contrast enhancement (DCE) MR imaging between primary cervical tumors and normal cervical tissue.
- Trial name
- MRI (NCT01060033)
- Testing
- MR Spectroscopy, Fat-Saturation and Diffusion-Weighted Imaging, Dynamic Contrast Enhancement MRI (MR-DCE)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Washington University School of Medicine
Movement Disorders
Evaluation of Diffusion MRI as a Tool in Planning Deep Brain Stimulation (DBS)
The purpose of this study is to explore the relationship between deep brain stimulation implantation site and DTI (diffusion tensor imaging) derived measures for the region and later compare this to the clinical treatment…
- Trial name
- NCT01975532
- Volunteers
- 13 people
- Sponsor
- University of Aarhus
Aging, Music
Brain Imaging and Behavioural Changes Following Cued-movement Training of Finger Sequences in Healthy Older Adults
The goal of this study is to examine changes in the brain, behavior, and personal experience when music is used to guide learning of finger movement sequences (compared to visual stimuli alone) in healthy older adults.
- Conditions
- Aging, Music, Motor Activity, Magnetic Resonance Imaging
- Trial name
- NMSOA (NCT06174740)
- Testing
- Music-cued audiovisual motor training, Visually-cued motor training
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiteit Leiden