Clinical trials: Digestive Discomfort
Digestive System Disorders
A Study to Determine if Aquamin (as AquaCal and AquaPT) Improves Digestive Discomfort
Digestive discomfort includes gastrointestinal symptoms such as abdominal pain, altered bowel habit, flatulence and bloating and can sometimes result from slower intestinal transit and other digestive irregularities.
- Trial name
- NCT01770808
- Testing
- AquaCal, AquaPT
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University College Cork
Gastrointestinal Symptoms
Effect of Bifidobacterium Lactis HN019 on Colonic Transit Time and Digestive Symptoms
The purpose of this study was to investigate the dose response effect of Bifidobacterium lactis HN019 supplementation on colonic transit time and gastrointestinal symptoms.
- Trial name
- NCT01171014
- Testing
- Bifidobacterium lactis HN019
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fonterra Research Centre
Gastrointestinal Discomfort
Impact of Dietary Fibre Consumption on Digestive Comfort
The purpose of this randomised, placebo-controlled, cross-over study is to compare the impact different fibres have on gastrointestinal symptoms when they are consumed individually or as mixtures in healthy adults.
- Trial name
- Fibrecomf (NCT05830032)
- Testing
- Soluble corn fibre, Inulin, soluble corn fibre and inulin
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Healthy Subjects
Evaluation of the the Efficacy of a Digestive Health Supplement in Healthy Subjects
The objective of this study is to evaluate the efficacy of a digestive health supplement via waist circumference measurements, daily bowel habit and symptom logs, and self-perception questionnaires (SPQ) over 4 weeks.
- Trial name
- NCT06680219
- Testing
- Active comparator
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Gut Health
Effectiveness of a Butyrate Formulation and Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms
The purpose of this study is the assess the effectiveness and safety of a Butyrate formulation and a Butyrate + Polyphenol formulation on gut health, permeability and associated symptoms
- Trial name
- NCT06419231
- Testing
- Butyrate Formulation, Butyrate + Polyphenol Formulation
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Constipation, Gastrointestinal Discomfort
Efficacy of LcS-Fermented Milk on Constipation-Related Symptoms in Filipino Adults
The primary purpose of this study is to investigate whether the consumption of a probiotic drink (with Lacticaseibacillus paracasei strain Shirota (LcS)) relieves constipation-related symptoms of Filipino adults, specifically its…
- Trial name
- NCT07083596
- Testing
- Experimental: Probiotic with LcS, Control
- Where
- Philippines
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Santo Tomas
Healthy Volunteers
Investigation of Benegut® on Immediate GI Discomfort Relief Caused by Acute Overfeeding in Healthy Subjects
To determine the relief of GI discomfort after overfeeding with a high caloric meal.
- Trial name
- NCT05603416
- Testing
- Perilla frutescens extract
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vital Solutions GmbH
Healthy Volunteers
The Effect of Wheat Germ on Gastrointestinal Discomfort, Blood Cholesterol and Postprandial Glycaemic Response
Wheat germ is a by-product of the wheat-milling industry with high nutritional value and therefore could be used as a raw source for the preparation of food products such as bread, cookies, muffins, etc.
- Trial name
- NCT02405507
- Testing
- wheat bread with wheat germ, wheat bread without wheat germ
- Where
- 2 sites in Portugal
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Moderate Gastrointestinal Discomfort
Investigating the Effectiveness of 2 Different Doses of BIOHM FX Probiotic Blend in Improving Digestive Symptoms
The rationale for this study is to observe the effect of two different doses of a consumer-grade probiotic product called FX Probiotic Blend on digestive symptoms in individuals with moderate gastrointestinal discomfort.
- Trial name
- NCT06782945
- Testing
- BIOHM FX Probiotic Blend
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Biohm Technologies
Gastrointestinal Symptoms, Bloating
A Clinical Trial to Evaluate the Effects of Super Liver Liquid Drops on Gut Health, Digestive Comfort, and Daily Energy Levels
This is a decentralized (fully virtual), single-group, open-label, prospective clinical trial evaluating the effects of Super Liver Liquid Drops, a liquid botanical dietary supplement, on gut health, digestive comfort, energy…
- Conditions
- Gastrointestinal Symptoms, Bloating, Digestive Discomfort, Low Energy Levels
- Trial name
- NCT07742657
- Testing
- Super Liver
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- SuperBonsai Inc.
Digestive Irregularity, Digestive Discomfort
The PRIDE Study Probiotics on Regulation and Improving Digestive hEalth
The purpose of this study is to determine the effect of probiotic supplemented yogurt in reducing colonic transit time (CTT) in females between the ages of 18-65 years old.
- Conditions
- Digestive Irregularity, Digestive Discomfort, History of Straining During Bowel Movements, History of Hard or Lumpy Stools
- Trial name
- PRIDE (NCT01203462)
- Testing
- Probiotic strain of Bifidobacterium, No Bifidobacterium
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Constipation, Gastrointestinal Discomfort
Clinical Evaluation of the Effects of EpiCor on Digestive Comfort
Previous in vitro studies suggest that EpiCor is well fermented in the colon and has prebiotic potential. The repeated long-term administration of low doses of EpiCor in the Simulator of the Human Intestinal Microbial Ecosystem…
- Trial name
- NCT03051399
- Testing
- EpiCor
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- ProDigest
Functional Gastrointestinal Disorders (FGIDs), Infant Discomfort
Effects of Goat Milk Formula on Gastrointestinal Comfort and Growth in Infants
Infant gastrointestinal discomfort is common in early life and can affect feeding, sleep, and overall well-being. Goat milk formula, due to its unique protein composition and smaller fat globules, may be easier to digest and…
- Trial name
- NCT07778927
- Testing
- Goat Milk Formula, Cow Milk Formula
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Colorectal Cancer, Adenomas
Colonoscopy Screening Using a Novel Slim Colonoscope - a Randomized Controlled Trial
The purpose of this study is to compare the performance of a new prototype colonoscope with a standard colonoscope used world-wide today.
- Trial name
- NCT01370928
- Testing
- Olympus PCF-Y0014-L, Standard colonoscope
- Where
- Norway
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Digestive Discomfort
A Study on the Effects of A2 Milk on Gut Beneficial Bacteria Growth and Digestion Improvement
The aim of this study is to evaluate the effects of A2 milk on gut beneficial bacteria growth, antioxidant activity , digestion, and inflammation improvement
- Trial name
- NCT06870097
- Testing
- A2 Milk, A1/A2 Milk
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Digestive Discomfort
Evaluation of the Efficacy and Safety of A2 Milk on Digestion
The aim of this study is to evaluate the efficacy and safety of A2 milk versus a control (A1/A2 milk) in individuals with digestive discomfort following milk consumption.
- Trial name
- NCT06252636
- Testing
- A2 Milk, A1/A2 Milk
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Constipation
Effects of Cultura Yoghurt in Relation to Transit Time and Digestive Discomfort in Healthy Women and Men
The aim of this study is to determine the effect of cultura yoghurt on transit time and digestive discomfort during 2 weeks of treatment in comparison to placebo in healthy women and men.
- Trial name
- NCT01102036
- Testing
- Cultura L casei F19, acidophilus La5 , B lactis Bb 12, Yoghurt without probiotics
- Where
- Sweden
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Good Food Practice, Sweden
Healthy
The Effect of Post Colonoscopy Abdominal Massage on Abdominal Pain, Distension, Discomfort and Patient Satisfaction
Background: Abdominal pain, distension, and discomfort are the most frequently seen side effects after colonoscopy. These side effects can cause physical and mental results and increased workloads and care costs.
- Trial name
- NCT04979351
- Testing
- Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Hunger, Depression
Carbohydrate Rich Drink Reduces Pre-endoscopic Discomfort for Patients Going for Elective Endoscopic Procedures
The study is a randomised controlled trial that aims to evaluate whether carbohydrate loading pre-endoscopy can improve patients' overall satisfaction and is not associated with negative impact on endoscopic quality or increased…
- Conditions
- Hunger, Depression, Anxiety, Vomiting
- Trial name
- NCT05342116
- Testing
- Nestle Preload, Water
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Gastrointestinal Disorders
To Assess the Effect of Collagen on Gastrointestinal Discomfort in Healthy Adults With Gastrointestinal Symptoms.
This study will enroll healthy adults with perceived gastrointestinal symptoms to evaluate the effect of collagen peptides compared to placebo.
- Trial name
- NCT06937801
- Testing
- Collagen Peptide
- Where
- Canada
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Rousselot BVBA