Clinical trials: Digestive System Fistula
Crohn's Disease
Exclusive Enteral Nutrition Therapy for Active and Complicated Crohn's Disease
The goal of this observational study is to evaluate the effectiveness and safety of exclusive enteral nutrition (EEN) in adults with active Crohn's disease (CD), particularly in patients with complicated disease such as…
- Trial name
- EEN-CD (NCT07504510)
- Testing
- Exclusive Enteral Nutrition
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Gastric Fistula
Endoscopic Treatment of Intestinal Fistulas and Perforations
Background: T-shaped tissue anchors have promise to close incisions and perforations of the intestines securely. The closure of perforations, gastro-gastric, or intestinal fistulas usually requires invasive open or laparoscopic…
- Trial name
- NCT00835458
- Testing
- gastro-gastric fistula closure
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Legacy Health System
Anal Fistula
Endorectal Three-dimensional Ultrasound in the Diagnosis of Cryptogenic Fistulas of the Rectum.
Prospective comparative parallel ultrasound diagnostic transrectal study in the diagnosis of cryptogenic fistulas of the rectum
- Trial name
- NCT03743701
- Testing
- The method of transrectal ultrasound in В-mode, The method of transrectal ultrasound examination using three-dimensional image reconstruction.
- Where
- Russia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Anal Fistula
Anal Fistulae Internal Opening Closure by OTSC Clip After Video Assisted Tract Fulguration
This study is expected to recruit 20-25 cases treated with video assisted anal fistula treatment. Additionally the internal opening of the fistulae will be closed by an OTSC clip.
- Trial name
- VAAFT-OTSC (NCT06243302)
- Testing
- OTSC Closure After VAAFT
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara University
Pancreatic Fistula
Isolated Roux Loop Versus Conventional Pancreaticojejunostomy Following Pancreaticoduodenectomy
Pancreaticoduodenectomy is a commonly applied operation for the treatment of benign and malignant diseases of periampullary region.
- Trial name
- NCT03671031
- Testing
- isolated roux loop, single loop
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people
- Sponsor
- Inonu University
Anal Fistula Surgery, Anal Fistula
The Use of Electronic Bidets Compared to Water Rinsing After Surgery for Anal Fistula or Haemorrhoidal Disease: a Pilot Study
There is still much to discover in the field of proctological postoperative care. There has already been some, albeit very little, research about its use post-haemorrhoidectomy as well as its possible effect on anal fissures, but…
- Conditions
- Anal Fistula Surgery, Anal Fistula, Hemorrhoidal Disease, Hemorrhoid Surgery
- Trial name
- bidet (NCT07874711)
- Testing
- Electronic bidet, standard water rinsing
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel
Pancreatic Neoplasms, Pancreatic Fistula
Preoperative EUS Elastography for Pancreatic Texture and POPF Prediction After PD
This prospective study evaluates whether preoperative endoscopic ultrasound elastography (EUS-E) can predict pancreatic texture during surgery and risk of postoperative pancreatic fistula (POPF) in 100 patients undergoing…
- Trial name
- EUS-E (NCT07139236)
- Testing
- Preoperative Endoscopic Ultrasound Elastography (EUS Elastography)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Anal Fistula, Rectal Fistula
A Prospective Evaluation of the Strattice-LIFT to Treat Anal Fistula
This clinical trial will evaluate the safety and efficacy of the Strattice-LIFT procedure to treat anal fistulas.
- Conditions
- Anal Fistula, Rectal Fistula, Fistula in Ano, Transsphincteric Fistula
- Trial name
- NCT02423330
- Testing
- Strattice-LIFT
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Rush University Medical Center
Enterocutaneous Fistula
Stromal Vascular Fraction (SVF) for Treatment of Enterocutaneous Fistula (HULPUTC)
The purpose of this study is to determine safety of Stromal Vascular Fraction (SVF) for the treatment of enterocutaneous fistula.
- Trial name
- HULPUTC (NCT01584713)
- Testing
- Adipose-derived stem cells without expanded
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Pancreatic Fistula
Comparison of Feasibility Between Internal and External Pancreatic Drainage in Pancreaticoduodenectomy
Pancreatic fistula is one of the most serious complication after pancreatoduodenectomy. To reduce pancreatic fistula, many authors recommend pancreatic stent in pancreatojejunostomy.
- Trial name
- NCT01023594
- Testing
- Pancreatic stent
- Where
- 8 sites in South Korea
- Volunteers
- 328 people
- Sponsor
- Seoul National University Hospital
Fistula in Ano
PRP Use in Treatment of Fistula Ano
In treatment of perianal fistula several methods are described. However, since the Hippocrates basics of surgical treatment has not changed very much.
- Trial name
- NCT04187651
- Testing
- platelet rich plasma
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Uşak University
Pancreatic Fistula
Clinically Relevant Pancreatic Fistula After Pancreaticoduodenectomy
Patients who are diagnosed with periampullary cancer will be performed pancreaticoduodenectomy with 3 types of pancreatic-jejunal anastomosis reconstructions.
- Trial name
- NCT05017207
- Testing
- Pancreaticoduodenectomy
- Where
- Vietnam
- Volunteers
- 183 people
- Sponsor
- Vo Truong Quoc
Pancreatic Fistula
External Pancreatic Stent in Pancreaticojejunostomy
Pancreatic fistula is one of the most serious complication after pancreatoduodenectomy. To reduce pancreatic fistula, many authors recommend pancreatic stent in pancreatojejunostomy.
- Trial name
- NCT06743516
- Testing
- Pancreaticojejunostomy with external stent, Pancreaticojejunostomy without external stent
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Pancreatic Carcinoma
Endoscopic Botulinum Toxin Injection in the Prevention of Postoperative Pancreatic Fistula Following Distal Pancreatectomy
This phase II trial studies the effect of botulinum toxin (Botox) in preventing postoperative pancreatic fistula after distal pancreatectomy.
- Trial name
- NCT04965311
- Testing
- Botulinum Toxin Type A
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- OHSU Knight Cancer Institute
Surgery--Complications, Pancreas Disease
Prospective Snapshot Audit of Distal Pancreatectomy in Spain
Distal pancreatectomy is the surgical technique performed to treat many pancreatic diseases located in neck and tail of the pancreas.
- Conditions
- Surgery--Complications, Pancreas Disease, Pancreatic Fistula
- Trial name
- Spadispan (NCT04900012)
- Testing
- Distal pancreatectomy
- Volunteers
- 500 people
- Sponsor
- Hospital General Universitario de Alicante
Tracheoesophageal Fistula, Esophageal Atresia With Tracheo-esophageal Fistula
Camera-based Endoscopy Allows Spontaneous Breathing Diagnostic Management in Neonates With Tracheoesophageal Fistula
The investigators aim to compare rigid tracheoscopy versus flexible tracheo-video-endoscopy in neonates requiring diagnostic assessment before undergoing a congenital tracheoesophageal fistula repair.
- Trial name
- CBESB (NCT07687628)
- Testing
- tracheoscopy performed with rigid optical tracheoscopy, flexible video endoscopy of trachea
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Papa Giovanni XXIII Hospital
Pancreatic Tumor, Benign, Pancreatic Neuroendocrine Tumor
Pancreatic Fistula After Minimally Invasive Enucleation
Patients suffering from postoperative pancreatic fistula (POPF) after minimally invasive enucleation (MIEN) show a characteristic pattern of longer duration and milder symptoms, which is different from pancreatic fistula after…
- Conditions
- Pancreatic Tumor, Benign, Pancreatic Neuroendocrine Tumor, Solid Pseudopapillary Tumor of the Pancreas
- Trial name
- NCT06557408
- Where
- China
- Volunteers
- 173 people
- Sponsor
- Fudan University
Crohn's Disease
Vedolizumab IV 300 mg in the Treatment of Fistulizing Crohn's Disease
The purpose of this study is to evaluate the percentage of participants with perianal fistula healing at Week 30 in 2 different dose regimens of vedolizumab intravenous (IV) 300 milligram (mg) in participants with fistulizing…
- Trial name
- ENTERPRISE (NCT02630966)
- Testing
- Vedolizumab
- Where
- 18 sites in United States, Canada and 5 more
- Volunteers
- 34 people
- Sponsor
- Takeda
Pancreas Neoplasm, Pancreas Cancer
Incidence of POPF in the Resection of the Left Pancreas With RFAT
This study evaluates the impact of the Radiofrequency assisted transection on the rate of postoperative pancreatic fistula (POPF) after performing distal pancreatectomies, central pancreatectomies and pancreatic enucleation
- Conditions
- Pancreas Neoplasm, Pancreas Cancer, Pancreatic Adenocarcinoma, Benign Pancreas Tumor
- Trial name
- RFATPancreas (NCT03570502)
- Where
- Spain
- Volunteers
- 38 people
- Sponsor
- Hospital del Mar
Pancreas Disease, Complication,Postoperative
Early Drain Removal Versus Standard Drain Management After Distal Pancreatectomy (Early-Dist)
Main indications for distal pancreatectomy (DP) are pancreatic body and tail tumors including ductal adenocarcinoma, neuroendocrine tumors, and cystic neoplasms.
- Conditions
- Pancreas Disease, Complication,Postoperative, PROMs, Pancreatic Fistula
- Trial name
- Early-Dist (NCT04609137)
- Testing
- Early drain removal, Standard drain removal
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- IRCCS San Raffaele