Clinical trials: Digestive System Surgical Procedures
Carcinoma, Hepatocellular, Liver Dysfunction
Evaluation of Remnant Liver Function Using Primovist-enhanced MRI Before Resection/Ablation of Hepatocellular Carcinoma
The purpose of this study is to determine whether the global and segmental hepatic uptake and excretion of Gd-EOB-DTPA on Gd-EOB-DTPA-enhanced liver MRI correlates with standard liver function test results in the patients with…
- Trial name
- LiFE (NCT01490203)
- Testing
- Gd-EOB-DTPA, MRI
- Where
- 4 sites in South Korea
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Chronic Pancreatitis
Endoscopic Ultrasound (EUS) Features of Chronic Pancreatitis
The purpose of this study is to correlate Endoscopic Ultrasound (EUS) criteria for chronic pancreatitis with surgical pathology.
- Trial name
- NCT01442454
- Testing
- chronic pancreatitis
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cholecystitis, Stress
The Effect of the Stress Ball Applied Before Colocystectomy Surgery on Patients; Surgical Fear, Anxiety and Comfort.
Cholecystectomy is the most common major abdominal surgical procedure in western countries. Patients may experience fear and anxiety before surgery.
- Conditions
- Cholecystitis, Stress, Fear, Comfort
- Trial name
- NCT06345768
- Testing
- Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Colonic Carcinoma, Laparoscopic Right Hemicolectomy
Standardizing Right Hemicolectomy for Colon Cancer
A surgical intervention might be highly variable amongst surgeons and centers. This variability has a potential relevance concerning clinical outcomes.
- Conditions
- Colonic Carcinoma, Laparoscopic Right Hemicolectomy, Standardisation, Training
- Trial name
- Right (NCT04889456)
- Testing
- Implementation standardised laparoscopic right hemicolectomy with proctoring, Implementation standardised laparoscopic right hemicolectomy without proctoring
- Where
- Netherlands
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Complication of Surgical Procedure, Infections
Pathogenesis of Postoperative Infections and Biomarkers for Early Diagnosis of it
Infections remain a prevalent complication after major abdominal surgery. The common belief that most surgical site infections (SSIs) following elective surgery with modern antiseptic techniques are due to intraoperative…
- Trial name
- NCT06513598
- Testing
- Major visceral surgery for gastrointestinal cancer
- Where
- 2 sites in Lithuania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos
Hemorrhoids
Laser Hemorrhoidoplasty Versus Open Surgical Hemorrhoidectomy in Second and Third Degree Piles
The study aims to compare the pain , duration of intervention and long term outcomes of laser hemorrhoidoplasty versus open surgical hemorrhoidectomy
- Trial name
- NCT05770141
- Testing
- laser hemorrhoidoplasty, open surgical hemorrhoidectomy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Colorectal Cancer, Tumor
Microbiome in Colorectal Cancer Onset and Progression
This is an observational study with the goal to improve the robustness of the scientific evidence linking Fusobacterium nucleatum (Fn) and/or other microorganisms to colorectal cancer (CRC) onset and/or progression.
- Conditions
- Colorectal Cancer, Tumor, CRC, GI Cancer
- Trial name
- NCT05368688
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Viome
Colon Cancer, Rectal Cancer
Pilot Study Evaluating the Efficacy of AlloMEM After Loop Ileostomy
The objective of this study is to investigate whether the use of Human Peritoneal Membrane (HPM) in a temporary loop ileostomy is beneficial to patients.
- Trial name
- AlloMem (NCT01113736)
- Testing
- AlloMEM™
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Colorectal Cancer, Liver Metastasis
Surgical Recovery After Left Lateral Hepatic Sectionectomy: Laparoscopic Versus Open Surgery.
The ORANGE II trial is a double blinded randomised controlled trial that will provide evidence on the merits of laparoscopic surgery in patients undergoing a left lateral hepatic sectionectomy in terms of time to functional…
- Conditions
- Colorectal Cancer, Liver Metastasis, Liver Disease
- Trial name
- ORANGE II (NCT00874224)
- Testing
- laparoscopic left lateral hepatic sectionectomy, open left lateral hepatic sectionectomy
- Where
- Netherlands
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Intraabdominal Abscess After Procedure, Leakage
Outcome After Laparoscopic Surgery for Peptic Ulcer Perforation
Despite advances in laparoscopic surgery for perforated peptic ulcer (PPU), intra-abdominal abscess (IAA) is recognized as one of the commonly reported complications with relation to the extent of infectious abdominal…
- Conditions
- Intraabdominal Abscess After Procedure, Leakage, Pneumonia, Operation Wound; Infection
- Trial name
- NCT05147870
- Testing
- Peritoneal irrigation, Suction only
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Wei-Jung
Hepatocellular Carcinoma
A Trial of Licartin for Preventing Tumor Recurrence After Liver Resection
The aim of this study is to analyze the therapeutic effect of adjuvant Licartin therapy after resection.Patients receiving curative resection (R0) were randomized to postoperative Licartin group and no Licartin group.
- Trial name
- NCT00819650
- Testing
- Licartin (generic name,[131I]metuximab injection)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Crohn's Disease, Inflammatory Bowel Disease
A Comparison of Ultrasound Guided Transversus Abdominis Plane Nerve Block Techniques
Postoperative pain can pose significant challenges in the postoperative recovery of patients undergoing major colorectal surgery. Traditionally, opioids have played an important role in treating postoperative pain.
- Conditions
- Crohn's Disease, Inflammatory Bowel Disease, Postoperative Pain
- Trial name
- NCT02538679
- Testing
- US TAP Bupivacaine/Epinephrine, Lap TAP Bupivacaine/Epinephrine
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Gastric Cancer
ctDNA-MRD Monitoring After Resection in Gastric Cancer
Numerous studies have demonstrated that circulating tumor DNA (ctDNA)-based molecular residual disease (MRD) detection has significant clinical value in postoperative recurrence monitoring, adjuvant treatment decision-making, and…
- Trial name
- MRD-GC (NCT06893133)
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Peking University
Rectocele
Trial to Determine Which of Two Surgical Techniques Works Better to Correct Vaginal Bulging
Women with vaginal bulging who are undergoing laparoscopic sacrocolpopexy at Clarian Health are eligible to enroll in this study.
- Trial name
- NCT00988975
- Testing
- Insertion of pelvicol graft
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Urogynecology Associates, Indiana
Body Image Disorder
Prevention of Body Image Disorder by Nurse Intervention on the Patient and Family Prior to Breast and Colon Surgery
This is a non-blinded, randomized, controlled clinical trial consisting of 64 participants, which aims to assess the effectiveness of a nursing intervention for family members and patients prior to surgery to prevent body image…
- Trial name
- NCT03726801
- Testing
- HEALTH EDUCATION
- Where
- Spain
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Pancreatic Cancer
Resection of the Nerve Plexus on the Right Half of Celiac and SMA Associated With Extended Pancreatoduodenectomy in the Surgical Treatment for Adenocarcinoma of the Head of Pancreas
This study is performed to confirm whether resection of the nerve plexus on the right half of celiac and SMA associated with extended pancreatoduodenectomy could improve survival and relieve pain of pancreatic cancer patients.
- Trial name
- NCT02514928
- Testing
- resection of the nerve plexus on the right half of celiac and SMA associated with extended pancreatoduodenectomy, standard pancreatoduodenectomy
- Where
- China
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Fudan University
Hepatocellular Carcinoma
A Trial of Adjuvant Transarterial Chemoembolization (TACE) for Preventing Tumor Recurrence After Liver Resection
The aim of this study is to analyze the therapeutic effect of adjuvant TACE after resection.Patients receiving curative resection (R0) were randomized to postoperative TACE group and no TACE group.
- Trial name
- NCT00820053
- Testing
- epirubicin and lipiodol
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Periodontitis, Inflammatory Bowel Diseases
The Effect of Non-Surgical Periodontal Therapy on Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is a chronic and recurrent inflammatory disease of the gastrointestinal tract characterised by complex interactions between genetic susceptibility, environmental factors, microbiota and host…
- Trial name
- NCT06245278
- Testing
- ELISA (Enzyme-Linked ImmunoSorbent Assay)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Biruni University
Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke
THE EFFECT OF SURGICAL MASK AND N95 MASK USE ON SURGICAL SMOKE IN OPERATING ROOM NURSES
This study was conducted to compare the effect of surgical mask and N95 mask use on physical symptoms due to surgical smoke in operating theatre nurses.
- Conditions
- Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke, Headache, Dizziness
- Trial name
- NCT07404956
- Testing
- Surgical Mask, N95 Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Gall Stones
Intraperitoneal Techniques of Local Anaesthesia During Laparoscopic Cholecystectomy
Pain following laparoscopic cholecystectomy (LC) results in morbidity and is a barrier to same day discharge. In several trials local anaesthetic (LA) washed over the liver and gall bladder decreases pain.
- Trial name
- NCT01090882
- Testing
- Bupivocaine, 0.9% normal saline solution
- Where
- United Kingdom
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust