Clinical trials: Digital
Neurodevelopmental Disorder (Diagnosis)
Transdiagnostic Dimensional Profiling of Neurodevelopmental Disorders
In recent years, the growing awareness of the multifactorial nature of neurodevelopmental disorders has stimulated interest in transdiagnostic approaches aimed at investigating underlying etiological mechanisms beyond traditional…
- Trial name
- RDoC-CRAB (NCT07544199)
- Testing
- Neuropsychological assessment
- Volunteers
- 300 people
- Sponsor
- IRCCS Eugenio Medea
Digital Mucous Cyst
A New Surgical Treatment Technique "Aspiration and Percutaneous Capsulotomy" for Digital Mucous Cyst
Digital mucous cysts (DMCs) are a benign rubbery cystic lesion which usually involve the dorsal or lateral side of DIP joint (digital interphalangeal joint) or proximal nail fold.
- Trial name
- NCT03199248
- Testing
- Aspiration with percutaneous capsulotomy For digital mucous cysts
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Tendon Injury - Hand
Tranexamic Acid Effect on Digit Function Following Primary Repair of Traumatic Digit Flexor Tendon Injuries
This study evaluates the effect of pre-operative treatment with IV Tranexamic Acid on post-operative digit function, in patients that underwent surgical repair of traumatic zone 1 or zone 2 digit flexor tendon tear.
- Trial name
- NCT04178655
- Testing
- Tranexamic acid injection
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Biometric Changes During Meditation
Digital Medicine in Meditation
This study will investigate the acute response to meditation during a week-long meditation retreat at the Chopra Center as measured by the continuous, simultaneous monitoring of numerous biometric parameters in selected cohorts…
- Trial name
- DigMed2 (NCT01975415)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Scripps Translational Science Institute
Myocardial Infarction, Kinesiophobia
Effect of Home-based Exercise Plan Mediated by Use of Digital Health App on Kinesiophobia and Functional Capacity
To evaluate the effect of home-based exercise plan mediated by a digital health application on kinesiophobia and functional capacity in sedentary post myocardial infarction patients.
- Conditions
- Myocardial Infarction, Kinesiophobia, Sedentary Behavior
- Trial name
- NCT07138911
- Testing
- Intervention group, Control group
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Riphah International University
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
Clinnova-MS: A Prospective Cohort Study of Patients With Multiple Sclerosis (Switzerland)
This prospective cohort study is part of the Clinnova programme and aims to (i) identify clinical imaging and omics characteristics associated with early Multiple Sclerosis (MS) and with transitioning phases to progressive MS, as…
- Conditions
- Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary Progressive
- Trial name
- NCT06526364
- Testing
- All participants will be asked to provide data and samples for collection and analysis.
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Basel, Switzerland
Rotator Cuff Tear, Telemedecine
Remote App-based Rehabilitation After Rotator Cuff Repair
The aim of this study was to evaluate the effectiveness of a mobile application for telemedicine in patients recovering from arthroscopic rotator cuff tendon repair.
- Conditions
- Rotator Cuff Tear, Telemedecine, Rotator Cuff Injuries
- Trial name
- NCT07555704
- Testing
- Telerehabilitation, Conventional home exercise program
- Where
- Vietnam
- Volunteers
- 102 people
- Sponsor
- Hanoi Medical University
Systemic Sclerosis
Subcutaneous Injections of ASC to Heal Digital Ulcers in Patients With Scleroderma.
Ischemic digital ulcers (DUs) are a frequent complication in systemic sclerosis with a major impact on hand function and quality of life.
- Trial name
- ADUSE (NCT04356755)
- Testing
- AdMSC
- Where
- 7 sites in France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Toulouse
Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Immediate Dental Implant Placement
Influence of Provisional Restoration Type on Outcomes of Immediate Implant Placement and Loading
A randomized clinical trial comparing 3D-printed resin and CAD/CAM-milled PMMA provisional restorations used for immediate loading of fully digitally guided immediate implants.
- Conditions
- Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Immediate Dental Implant Placement, Immediate Loading, Provisional Restoration
- Trial name
- PRODIGI (NCT07700771)
- Testing
- 3D-Printed Resin Provisional Crown, CAD/CAM-Milled PMMA Provisional Crown
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Multiple Sclerosis
Prospective Longitudinal Monocentric Study to Evaluate the Syde® Digital Endpoint in Patients With Multiple Sclerosis
The study aims to assess the validity of real-world activity monitoring by the Syde® wearable device in subjects with multiple slclerosis.
- Trial name
- NHS-MS-EGYPT (NCT06346704)
- Testing
- Digital HealthTechnology
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- SYSNAV
Knee Osteoarthristis, Obesity & Overweight
E-Health Lifestyle Intervention for Arthritis: A Pilot RCT on Feasibility
Knee osteoarthritis and obesity are common health problems in Hong Kong, especially among South Asian communities, where obesity rates are much higher than the general population.
- Trial name
- CHALAANE (NCT07786038)
- Testing
- Digital Health Intervention, Inactivated Smartband for Activity Monitoring
- Where
- 2 sites in Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Education, Surgical Nursing
Digital Flashcards for Fluid and Electrolyte Education in Surgical Nursing: A Solomon Four-Group Study
This study aims to investigate the effect of the digital flashcard method, compared to traditional lecturing, on students' knowledge levels and self-efficacy perceptions regarding fluid-electrolyte balance in the surgical nursing…
- Conditions
- Education, Surgical Nursing, Teaching Methods
- Trial name
- Flashcards (NCT07869459)
- Testing
- Digital Flashcard Training & Pre-test/Post-test, Digital Flashcard Training & Post-test Only, Standard Lecture Only & Pre-test/Post-test
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Infection Wound, Disruption of Nerve Repair
Repair of Infective Wound Associated With Nerve Defect in the Finger Using A Bipedicled Nerve Flap
A combination of soft tissue and digital nerve defects in the finger results in sensory loss of the finger pulp. Reconstruction of these combined injuries is difficult.
- Trial name
- NCT01707654
- Testing
- Nerve flap
- Where
- China
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Stuttering, Adult
Effects of Al-Lisaan Urdu Digital Software for Self-Assessment and Treatment of Adult Stutters
The study plans to find the efficacy of a digital application/software, Al-lisan that adult stutters can be used for assessment and management of their stuttering.
- Trial name
- Al-Lisaan (NCT06059729)
- Testing
- Al-Lisaan
- Where
- 2 sites in Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Dementia, Neurocognitive Disorders
Cognitive Stimulation in Older Adults With Alzheimer's Disease
This multicentre study, employing a randomised controlled repeated measures experimental design, will be conducted in several Portuguese institutions that provide care and support services for older adults diagnosed with mild to…
- Conditions
- Dementia, Neurocognitive Disorders, Cognitive Impairment, Cognitive Dysfunction
- Trial name
- NCT07041008
- Testing
- Digital intervention, Physical/Analogue Intervention
- Where
- 39 sites in Portugal
- Volunteers
- 514 people
- Sponsor
- Rsocialform - Geriatria, Lda
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Cognitive-Behavioral Stress Management Device for the Treatment of Anxiety and Depressive Symptoms in Patients With Stage I-III Breast or Lung Cancer
This phase II trial studies the effect of a digital application (app), BNT001, on cognitive-behavioral stress management in patients with stage I-III breast or lung cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- BNT001 (NCT04705025)
- Testing
- Cognitive Behavior Therapy, Interview, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Binge Eating Disorder
Combining Digital Cognitive-behavior Therapy With Mindfulness Training for Binge Eating Disorder
The investigators will evaluate the acceptability and feasibility of a 16-session digital mindfulness-based and cognitive behavioral therapy (CBT) intervention for binge eating disorder (BED) + coached self-monitoring vs.
- Trial name
- NCT07212673
- Testing
- CBT-based Mindful Courage, Coached Self-Monitoring
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Yeshiva University
Triple Negative Breast Cancer
Deployment and Clinical Evaluation of an AI-powered Digital Oncology Biomarker Tool to guidE Treatment in TNBC
TILs have been shown to be predictive for response to neo-adjuvant chemotherapy in patients with TNBC in multiple studies (Level-1B evidence for clinical validity as per REMARK criteria).
- Trial name
- AIDOBE (NCT06396754)
- Testing
- AI-analysis on diagnostic and surgical specimens
- Volunteers
- 50 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Neuromuscular Diseases
Feasibility, Validation and Application of Digital Tools for the Follow-up of Neuromuscular Patient Mobility in Daily Living
The low prevalence of rare diseases hinders the design of clinical studies with sufficient statistical power to demonstrate the efficacy of new drugs.
- Trial name
- DT4RD (NCT05798325)
- Testing
- 2MWT, MFM32, MyoGrip
- Where
- 2 sites in France, United Kingdom
- Volunteers
- 40 people
- Sponsor
- Institut de Myologie, France
Digital Nerve Injuries
Sensory Recovery of Digital Nerves After Microsurgical Epineural Neurorrhaphy Alone or in Combination With Tisseel - RET
Evaluation of sensitivity after primary surgical treatment of digital nerve injuries with microsurgical epineural end-to-end neurorrhaphy alone or in combination with the fibrin glue Tisseel®
- Trial name
- RET (NCT05490940)
- Testing
- Tisseel®
- Where
- Switzerland
- Volunteers
- 74 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern