Clinical trials: Digital Mammography
Breast Screening
Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer
This randomized phase III trial studies digital tomosynthesis mammography and digital mammography in screening patients for breast cancer.
- Trial name
- NCT03233191
- Testing
- Digital Mammography, Digital Tomosynthesis Mammography, Laboratory Biomarker Analysis
- Where
- 149 sites in United States, Argentina and 9 more
- Volunteers
- 108,508 people, healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group
Breast Neoplasms
Delphinus SoftVue Prospective Case Collection - ARM 1
The SoftVue™ is a whole breast ultrasound system with an automated scanning curvilinear ring-array transducer that employs UST. It is currently cleared under FDA 510(k) K123209 and K142517 for use as both a B-mode ultrasonic…
- Trial name
- SV PCC ARM1 (NCT03257839)
- Testing
- Routine Full-Field Digital Mammography, Routine Digital Breast Tomosynthesis, Automated Whole Breast Ultrasound
- Where
- 10 sites in United States
- Volunteers
- 7,409 people, healthy volunteers welcome
- Sponsor
- Delphinus Medical Technologies, Inc.
Breast Neoplasms
Comparison of Full-Field Digital Mammography With Digital Breast Tomography for Screening Call-Back Rates
This multicenter trial using Hologic digital mammography units will evaluate the specificity of 2-D full field digital mammography (FFDM) versus a combination of 2-D and 3-D tomosynthesis imaging in breast cancer screening.
- Trial name
- NCT01236781
- Testing
- Screening Tomosynthesis, Diagnostic Tomosynthesis
- Where
- 2 sites in United States
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- American College of Radiology
Breast Cancer
Comparison of Contrast-enhanced Spectral Mammography (CESM) to MRI in Screening High Risk Women for Breast Cancer
This research study is comparing Dual-Energy Contrast-Enhanced Spectral Mammography (CESM) to MRI as a screening tool for breast cancer.
- Trial name
- NCT02275871
- Testing
- MRI, CESM
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Breast Cancer
Case Collection Study to Support Digital Mammography Image Software Change
The primary objective of this study is to compare image processing software to support a new image processing software application for a full-field digital mammography (FFDM) system.
- Trial name
- LIP2SIP (NCT00756496)
- Testing
- Mammography screening and diagnosis
- Volunteers
- 442 people, healthy volunteers welcome
- Sponsor
- Siemens Medical Solutions USA - CSG
Breast Cancer
Innovation in Mammography: Tomosynthesis Pathways
The study aims at evaluating the introduction of tomosynthesis in mammography screening, analyzing the benefits, disadvantages and feasibility in current clinical practice.
- Trial name
- IMPETO (NCT03587259)
- Testing
- Tomosynthesis, 2D mammography
- Where
- 2 sites in Italy
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Cancer Prevention and Research Institute, Italy
Breast Cancer
Tomosynthesis Mammographic Imaging Screening Trial
A randomized screening trial to compare the diagnostic accuracy of screening for breast cancer with three-dimensional digital breast tomosynthesis (DBT) plus two-dimensional full-field digital mammography (FFDM) versus FFDM alone.
- Trial name
- TMISTLead-in (NCT02616432)
- Testing
- Tomosynthesis
- Where
- 4 sites in Canada
- Volunteers
- 3,065 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Breast Cancer
Study of Dual-energy (DE) Contrast-enhanced (CE) Digital Mammography
This is a feasibility study to evaluate dual-energy (DE) contrast-enhanced (CE) digital mammography to detect breast cancer in patients with increased breast density (BI-RADS category c or d).
- Trial name
- NCT02995980
- Testing
- Dual-Energy Contrast-Enhanced (DECE) mammography, digital mammography
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Breast Cancer
Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts
The over-arching goal of the Contrast-Enhanced Spectral Mammography Imaging Screening Trial (CMIST) is to determine if dual-energy contrast-enhanced spectral mammography (CESM) can detect more cancers with fewer false positives…
- Trial name
- CMIST (NCT05625659)
- Testing
- Dual-Energy Contrast-Enhanced Spectral Mammography (CESM)
- Where
- 13 sites in United States, Canada
- Volunteers
- 2,032 people, healthy volunteers welcome
- Sponsor
- American College of Radiology
Breast Neoplasms, Breast Cancer Detection
Diagnostic Accuracy of Carebot AI MMG in Mammography Screening: Multicenter MRMC Study
This study evaluates the diagnostic performance of Carebot AI MMG, an artificial intelligence (AI)-enabled medical device for evaluating mammograms.
- Conditions
- Breast Neoplasms, Breast Cancer Detection, Breast Cancer - Female, Breast Cancer Screening
- Trial name
- CARE-MMG-MRMC (NCT07298252)
- Testing
- Carebot AI MMG software analysis
- Where
- 4 sites in Czechia, Slovakia
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Carebot s.r.o.
Breast Cancer
Artificial Intelligence in Mammography Screening in Norway
The purpose of this randomized controlled trial is to compare the number of breast cancers detected among women who had their screening mammograms interpreted by artificial intelligence (AI) in combination with one or two breast…
- Trial name
- AIMS Norway (NCT06032390)
- Testing
- AI assisted mammography screening interpretation, Standard mammography screening interpretation
- Where
- Norway
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Breast Cancer
Multi-Reader Multi-Case Controlled Clinical Trial to Assess the Fujifilm FFDM and DBT Reader Training Program
The purpose of this pilot is to assess the adequacy of the Fujifilm DBT Reader Study Training program to ensure that Readers participating in the Fujifilm DBT pivotal trial are properly trained in the reading and interpretation…
- Trial name
- NCT02685566
- Testing
- FFDM Plus DBT, FFDM
- Where
- 5 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fujifilm Medical Systems USA, Inc.
Breast Cancer, Breast Neoplasms
The Diagnostic Efficacy of Computer-Aided Detection (CAD) in Full-Field Digital Mammography (FFDM)- A Prospective Study
The purpose of this study is to evalute whether CAD (computer-aided detection) in FFDM (full-field digital mammography) can facilitate the detection rate of breast cancer on mammography compared with FFDM without CAD.
- Trial name
- NCT00173303
- Where
- Taiwan
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Breast Cancer
Xpress Digital Mammography System Images for Computer Aided Detection Development
The primary objective of this study is to acquire digital mammography images produced by the Xpress Digital Mammography System in order to develop Computer Aided Detection software and systems.
- Trial name
- NCT01061138
- Where
- 5 sites in United States
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- Konica Minolta Medical Imaging, USA
Breast Neoplasms
The Tomosynthesis Trial in Bergen - Part 2
The aim of the study is to compare early performance measures and economic aspects of organized breast cancer screening for women screened using digital breast tomosynthesis+synthetic mammography (DBT+SM) to women with a prior…
- Trial name
- To-Be 2 (NCT03669926)
- Testing
- Digital Breast Tomosynthesis+synthetic mammography
- Where
- Norway
- Volunteers
- 31,082 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Recall Rate, Cancer Detection Rate
Tomosynthesis in the Oslo Breast Cancer Screening Program
The Digital Breast Tomosynthesis (DBT) in the Oslo Mammography Screening Program will include women aged 50 to 69 years invited to the population-based mammography-screening program.
- Conditions
- Recall Rate, Cancer Detection Rate, False Positive Rate, Positive Predictive Value
- Trial name
- DBT (NCT01248546)
- Testing
- Digital breast tomosynthesis
- Where
- Norway
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Breast Cancer
Pilot 3D Mammography Reader Study to Assess Breast Cancer Detection in 3D Versus 2D Digital Mammography
The purpose of this pilot study is to provide credible performance estimate information in order to properly plan, design, and power a larger clinical study.
- Trial name
- 3DM (NCT01928992)
- Testing
- 3D, 2D
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fujifilm Medical Systems USA, Inc.
Breast Cancer Screening
B.Brilliant Revelation Comparision Study
This is an observational study to evaluate the MAMMOMAT B.brilliant system. All diagnostic decisions are made by the treating radiologist based upon standard of care clinical imaging acquired on FDA approved devices
- Trial name
- NCT07067788
- Testing
- Breast Imaging
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Mammogram Scheduled
Comparison of Stationary Breast Tomosynthesis and 2-D Digital Mammography in Patients With Breast Augmentation
Purpose:The aim of this research is to compare the 3D s-DBT (stationary digital breast tomosynthesis) and conventional 2-D digital mammography devices with regards to patient comfort and radiologist preference in women with…
- Trial name
- NCT02008032
- Testing
- Stationary Breast Tomosynthesis
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Breast Abnormalities
Assessment of Digital Breast Tomosynthesis (DBT) in the Screening Environment
The objective of this study is to demonstrate that digital breast tomosynthesis (DBT) in combination with full field digital mammography (FFDM) has the potential to reduce significantly baseline screening recall rates without a…
- Trial name
- NCT01106911
- Testing
- tomosynthesis and screening mammography
- Where
- United States
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh