Clinical trials: Dinoprostone Vaginal Insert
Induced Labor, Cervical Ripening
Low-dose Vaginal Misoprostol Versus Vaginal Dinoprostone Insert for Induction of Labor
Purpose: To compare the efficacy and safety of low-dose protocol of vaginal misoprostol and vaginal dinoprostone insert for induction of labor in women with post-term pregnancies.
- Conditions
- Induced Labor, Cervical Ripening, Obstetric Labor, Pregnancy
- Trial name
- MADUTER (NCT03744364)
- Testing
- Misoprostol 25 mcg, Dinoprostone 10mg
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Hospital Miguel Servet
Cervical Ripening, Labor Induction
Double Balloon Catheter Versus Dinoprostone Vaginal Insert for Cervical Ripening.
To compare the efficacy of transcervical double balloon catheters versus controlled release dinoprostone vaginal inserts for pre-induction cervical ripening in term women with unfavourable cervices.
- Trial name
- NCT01170819
- Testing
- Double balloon catheter, Dinoprostone 10 mg controlled-release vaginal insert
- Where
- Italy
- Volunteers
- 210 people
- Sponsor
- Università degli Studi dell'Insubria
IUCD Complication
Vaginal Misoprostol and Dinoprostone and Isonicotinic Acid Hydrazide Prior to Copper Intrauterine Device Insertion
To compare the effect of vaginal dinoprostone versus vaginal misoprostol and Isonicotinic Acid Hydrazide administered before the copper intrauterine device(IUD) insertion in reducing IUD inertion pain and the difficulty in…
- Trial name
- NCT04505943
- Testing
- Isonicotinic Acid Hydrazide, dinoprostine, misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aswan University Hospital
IUCD Complication
Vaginal Misoprostol and Dinoprostone Prior to Copper Intrauterine Device Insertion in Women
To compare the effect of vaginal dinoprostone versus vaginal misoprostol administered before the copper intrauterine device(IUD) insertion in reducing IUD insertion pain and the difficulty in inserting the IUD in multiparous…
- Trial name
- NCT04505917
- Testing
- dinoprostol, misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aswan University Hospital
IUD Insertion Pain
Vaginal Dinoprostone Administration Prior to Intrauterine Device Insertion
To investigate whether vaginal dinoprostone administered before the levonorgestrel-releasing intrauterine system(IUs) insertion reduces IUD insertion pain and difficulty in insertion in adolescents and young women.
- Trial name
- NCT04079140
- Testing
- Dinoprostone
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Cairo University
IUD Pain
Comparison of Vaginal Misoprostol and Dinoprostone Prior to Copper Intrauterine Device Insertion in Women Delivered Only by Cesarean Delivery
To compare the effect of vaginal dinoprostone versus vaginal misoprostol administered before the copper intrauterine device(IUD) insertion in reducing IUD insertion pain and the difficulty in inserting the IUD in women delivered…
- Trial name
- NCT04080349
- Testing
- Dinoprostone 3 mg, Misoprostol 200Mcg Tab
- Volunteers
- 300 people
- Sponsor
- Cairo University
Cervical Ripening, Labor, Induced
Safety/Efficacy Study Comparing the Misoprostol Vaginal Insert to Cervidil for Cervical Ripening and Induction of Labor
The purpose of this study is to determine whether the misoprostol vaginal insert (50 mcg and 100 mcg) can safely and effectively speed time to vaginal delivery compared to Cervidil (R) in women who need to have cervical ripneing…
- Trial name
- NCT00308711
- Testing
- Misoprostol vaginal insert 100 mcg, Misoprostol vaginal insert 50 mcg, Dinoprostone vaginal insert (Cervidil)
- Where
- 52 sites in United States, Canada
- Volunteers
- 1,308 people
- Sponsor
- Ferring Pharmaceuticals
PROM (Premature Rupture Of Foetal Membrane)
Cook Balloon Versus Propess After 12 Hours of Rupture of Membranes
The objective is to demonstrate the superiority of the strategy of labor induction by Cook® cervical ripening balloon between recommended strategy by dinoprostone (propess®) on the reduction of the time between cervical ripening…
- Trial name
- RUBAPRO (NCT03310333)
- Testing
- Propess® (dinoprostone), cook cervical pipening balloon
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Intrauterine Device
Vaginal Dinoprostone Administration Prior to a T380A Intrauterine Device Insertion in Nulliparous Women.
To investigate whether vaginal dinoprostone administered before intrauterine device (IUD) insertion reduces failed insertions, insertion-related complications and pain in nulliparous women.
- Trial name
- NCT03686085
- Testing
- Dinoprostone 3 mg
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Failed Induction of Labor
Foley Catheter Versus Dinoprostone Vaginal Insert for Induction of Labor in Parous Women at Term: A Randomized Trial
The purpose of this study is to assess the effectiveness and safety of transcervical foley catheter as compared to dinoprostone vaginal insertion for preinduction cervical ripening and labor induction in term parous women with…
- Trial name
- NCT01596296
- Testing
- Transcervical foley catheter, Dinoprostone 10mg
- Where
- South Korea
- Volunteers
- 154 people
- Sponsor
- Seoul National University Hospital
Reducing Time to Vaginal Delivery, Cervical Ripening
Efficacy & Safety Study Comparing Misoprostol Vaginal Insert (MVI) Versus Dinoprostone Vaginal Insert (DVI) for Reducing Time to Vaginal Delivery
The purpose of this study is to determine whether the Misoprostol Vaginal Insert (MVI) 200 microgram (mcg) can decrease the time to vaginal delivery compared to the Dinoprostone Vaginal Insert (DVI) 10 milligram (mg) in pregnant…
- Conditions
- Reducing Time to Vaginal Delivery, Cervical Ripening, Induction of Labor
- Trial name
- EXPEDITE (NCT01127581)
- Testing
- MVI 200, Dinoprostone Vaginal Insert (DVI)
- Where
- 34 sites in United States
- Volunteers
- 1,358 people
- Sponsor
- Ferring Pharmaceuticals
IUD Insertion Pain
Dinoprostone vs Misoprostol Before LNG-IUD Insertion
the aim of this study is to compare the safety and efficacy of vaginal dinoprostone vs vaginal misoprostol administration prior to IUD insertion in multiparous women regarding reduction in iud insertion pain
- Trial name
- NCT04301349
- Testing
- vaginal dinoprostone, vaginal misoprostol
- Volunteers
- 200 people
- Sponsor
- Cairo University
Contraception
Comparative Efficacy of Lidocaine Spray Versus Vaginal Dinoprostone in IUD Insertion
the aim of this study is to compare the safety and Efficacy of Lidocaine Spray Versus Vaginal dinoprostone in relieving pain during levonorgestrel IUD Insertion in nulliparous women
- Trial name
- NCT04339361
- Testing
- lidocaine spray, vaginal dinoprostone
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Cairo University
IUD Insertion
Vaginal Dinoprostone Administration Prior to an Intrauterine Device Insertion in Multiparous Women.
To investigate whether vaginal dinoprostone administered before intrauterine device (IUD) insertion reduces failed insertions, insertion-related complications, and pain in multiparous women.
- Trial name
- NCT04046302
- Testing
- Dinoprostone
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Cairo University
Induction of Labor Affected Fetus / Newborn
An RCT of a Synthetic Osmotic Cervical Dilator for Induction of Labour in Comparison to Dinoprostone Vaginal insErt
Induction of labour (where labour is started artificially) is traditionally carried out with a range of different drugs or by surgery (rupturing the membranes or 'waters').
- Trial name
- SOLVE (NCT03001661)
- Testing
- Dilapan-S, Dinoprostone
- Where
- United Kingdom
- Volunteers
- 674 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Labor Induction, Dinoprostone Vaginal Insert
Does Vaginal Washing Affect the Success Rate of the Labour Induction?
Investigators will use dinoprostone(Propess TM) for cervix ripening and labor induction in term pregnant women.Vaginal pH base is achieved with the effect of hormones in pregnancy and associated with this, vaginal infections…
- Conditions
- Labor Induction, Dinoprostone Vaginal Insert, Vaginal Infection, Effect Increased
- Trial name
- NCT03050684
- Testing
- vaginal lavage group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Dinoprostone Vaginal Insert
Assessing a Predicted Time to Delivery in the Context of Cervical Ripening With Dinoprostone Vaginal Insert
Induction of labor is a common obstetric procedure that is routinely performed worldwide. However, when cervical conditions are not favorable (bishop <6), induction of labor is preceded by cervical ripening, usually with…
- Trial name
- NCT03482531
- Testing
- mathematical model
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Cervical Ripening, Labor, Induced
Cervical Ripening Before Induction of Labour at Term: a Randomised Comparison of Prostin vs Propess
The aim of this study is to compare two different preparation
- Trial name
- NCT00545194
- Testing
- Prostaglandin E2
- Where
- France
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Intrauterine Device
Vaginal Dinoprostone Administration Prior to Insertion Levonorgestrel-releasing Intrauterine System in Women With no Previous Vaginal Delivery
To investigate whether vaginal dinoprostone administered before the levonorgestrel-releasing intrauterine system(IUs) insertion reduces failed insertions, insertion-related complications, and pain in Women With no Previous…
- Trial name
- NCT04045548
- Testing
- Dinoprostone
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
IUD Insertion Complication
Comparison of Vaginal Misoprostol and Dinoprostone Prior to Copper Intrauterine Device Insertion in Nulliparous Women
To compare the effect of vaginal dinoprostone versus vaginal misoprostol administered before the copper intrauterine device(IUD) insertion in reducing IUD inertion pain and the difficulty in inserting the IUD in nulliparous women.
- Trial name
- NCT04080336
- Testing
- Dinoprostone, Misoprostol
- Where
- Egypt
- Volunteers
- 129 people
- Sponsor
- Cairo University