Clinical trials: Disabilities
Age-related Mobility Decline
Locomotor Adaptation Training to Prevent Mobility Disability
This is an exploratory study designed to investigate the effects of aerobic dual belt treadmill walking versus traditional treadmill exercise on gait performance and functional capacity in older adults at risk for mobility…
- Trial name
- NCT02554916
- Testing
- Dual-Belt Exercise, Treadmill Exercise, Usual Care
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Florida
Down Syndrome
Early Ultrasound and Maternal Biochemical Markers to Evaluate the Risk of Down Syndrome During the First Trimester
The aim of the study is to evaluate the risk of Down syndrome during the first trimester of the pregnancy. The risk assessment is evaluated using early ultrasound and maternal biochemical markers.
- Trial name
- NCT00287417
- Testing
- echography, blood sample
- Where
- 7 sites in France
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Multiple Sclerosis, Healthy Controls Group - Age and Sex-matched
Measurement Properties of the Walking Adaptability Ladder Test and Foot Tap Test in Multiple Sclerosis
Walking and motor control impairments are among the most common manifestations experienced by people with multiple sclerosis (pwMS) and may already be present in individuals with mild disability.
- Trial name
- NCT07505355
- Where
- 4 sites in Belgium, Italy and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Attention Disturbances
Attention and Achievement: A Mind Wandering Investigation
This study assesses the impact of mind-wandering on reading and math.
- Trial name
- NCT05296252
- Testing
- mind-wandering intervention, mind-wandering comparison
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Houston
Parkinson's Disease
Psychiatric and Cognitive Manifestations of Parkinson's Disease
Parkinson's Disease (PD) is often thought of as affecting movement only. In fact, most patients also experience psychiatric and cognitive symptoms, sometimes from the disease itself, and sometimes as a side-effect of PD…
- Trial name
- NCT00360633
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Development Delay
Parent-Child Interaction in Garding Activities for Early Intervention Preschool Children
Post-COVID-19, children's reduced interaction with nature has hindered their sensory development, particularly affecting those with developmental delays.
- Trial name
- NCT06507358
- Testing
- Parent-Child Interaction group
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Trisomy 13, Trisomy 18
Multiple Gestation Study
The objectives of the clinical study are to demonstrate the accuracy of our new NATUS diagnostic method to determine the genetic health of the developing fetuses in a multiple gestation pregnancy from a maternal blood sample.
- Conditions
- Trisomy 13, Trisomy 18, Trisomy 21, Sex Chromosome Abnormalities
- Trial name
- NCT02278536
- Where
- 8 sites in United States, India and 1 more
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.
Perinatal Depression
Addressing Perinatal Depression in Deprived Areas of Istanbul, Turkey
In Turkey, the prevalence rate of perinatal depression has been estimated between 20%-40%, reflecting the global average of 25%.
- Trial name
- NCT04819711
- Testing
- Thinking Healthy Programme
- Where
- 2 sites in Turkey (Türkiye), United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Perran Boran
Low Back Pain
Validation of a Translation Into Spanish of the Oswestry Disability Index
The purpose of the study is to validate in Mexico a spanish translation of the 2.1a Oswestry Disability Index (ODI) version in patients with low back pain.
- Trial name
- NCT01649011
- Testing
- Application of the initial evaluation, Final application of scales
- Where
- Mexico
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- American British Cowdray Medical Center
Autism Spectrum Disorder (ASD), Intellectual Disability
Emotion Intensity Modulates Intention in ASD
This study used eye-tracking to examine how emotional expression intensity (low/medium/high) influences intention understanding in children with ASD, PDD, and TD during a puzzle-search task.
- Trial name
- NCT07597655
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Stroke, Knowledge, Attitudes, Practice
Effects of an Educational Intervention on Rehabilitation Clinicians' Practices for Health-related Outcomes After Stroke
The overall aim of this pilot study is to evaluate the feasibility of a study protocol for a future stepped wedge cluster randomized clinical trial (c-RCT) that will investigate the effects of an innovative KT intervention on 1)…
- Conditions
- Stroke, Knowledge, Attitudes, Practice, Physical Disability, Motor Skills Disorders
- Trial name
- NCT03807115
- Testing
- Implementation of stroke mobility guidelines
- Where
- 6 sites in Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- McGill University
Autism Spectrum Disorder, Intellectual Disability, Mild
Computer-Mediated Intervention to Enhance Emotional Competence in Children With Autism in Schools
Autism spectrum condition (ASC) is a neurodevelopmental disorder characterized fundamentally by social deficits. Emotional competence - the ability to express, recognize, understand, and regulate emotions - is a key aspect of…
- Trial name
- NCT05902832
- Testing
- EmotiPlay
- Where
- Israel
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel
Mental Disability, Mothers
The Effect of Home Accidents Prevention Training Given to Mothers of Mentally Disabled Children
The aim of this research is to examine the effect of education for home accidents given to mothers with mentally disabled children in the age group of 0-6.
- Conditions
- Mental Disability, Mothers, Home Injury
- Trial name
- NCT06633549
- Testing
- Home Accidents Prevention Training, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Being 18 Years of Age or Older, Having a Child Registered in a Special Education School
Awareness Of Home Accident Preventıon Among Parents Of Disabled Children And Evaluation Of The Basic First Aid Training Provided
This study was conducted to assess the awareness of parents of children with disabilities regarding the prevention of home accidents and the effectiveness of the basic first aid training provided.
- Conditions
- Being 18 Years of Age or Older, Having a Child Registered in a Special Education School, Providing Care for a Child With an Intellectual Disability, Providing Care for a Visually Impaired Child
- Trial name
- NCT07698860
- Testing
- Prevention of Household Accidents and Basic First Aid Training for Accidents
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Kayseri University
Mitochondrial Diseases, Developmental Delay Disorder
Reference Values of Intraepidermal Nerve Fiber Density in Children and Small Fiber Neuropathy in Neurodevelopmental Disorders
Background: Small-Fiber-Neuropathy describes the degeneration of mildly or unmyelinated nerve fibers and causes neuropathic pain and autonomic dysfunction.
- Conditions
- Mitochondrial Diseases, Developmental Delay Disorder, Small Fiber Neuropathy, Cerebral Palsy
- Trial name
- SFN_children (NCT05645874)
- Testing
- Skin biopsy
- Where
- Germany
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Chronic Low-back Pain
Aquatic and Land Exercises in Chronic Low Back Pain
Aquatic and Land Exercises on Chronic Low Back Pain
- Trial name
- NCT04378413
- Testing
- exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Baskent University
Plantar Fascitis, Resistance Training
Effects of High Load Strength Training With and Without Tissue Specific Planter Facia Stretching With Planter Fasciitis
The rationale behind examining the synergistic impacts of high load strength training and tissues pecific plantar fascia stretching activities in athletes diagnosed with plantar fasciitis arises from an acknowledged deficiency in…
- Conditions
- Plantar Fascitis, Resistance Training, Muscle Stretching Exercises
- Trial name
- NCT06536803
- Testing
- high load strength training and Tissue-specific plantar fascia stretching exercise for 12 weeks, high-load strength training with routine physiotherapy
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Prader Willi Syndrome, Adrenal Insufficiency
Diagnosis of Central Adrenal Insufficiency in Patients With Prader-Willi Syndrome
The purpose of this study is to determine presence of central adrenal insufficiency in children with Prader Willi Syndrome using low dose (1 mcg) ACTH stimulation test compared to results of overnight metyrapone test.
- Trial name
- NCT02368379
- Testing
- Low dose (1 mcg) ACTH stimulation test, Overnight metyrapone test
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Down Syndrome, Cardiovascular Risk Factor
Vascular Health and Risk Factors in Children With Down Syndrome
This is a prospective, multicenter, cross-sectional study to evaluate prevalence of vascular risk factors in children with Down Syndrome and to determine the association between vascular disease risk factors and objective markers…
- Conditions
- Down Syndrome, Cardiovascular Risk Factor, Atherosclerosis
- Trial name
- NCT04735874
- Testing
- Evaluate vascular disease risk factors in children with Down Syndrome, Determine the associations between cardiovascular disease risk factors and markers of early atherosclerosis in children with Down Syndrome
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Utah
Hearing Loss
Arabic Version of a New Tool Called HEAL-COMMAND to Evaluate Hearing Loss and Communication and Conversation Disability
Hearing loss is the fourth highest cause of disability globally. Current data suggest that approximately 5% of the world's population suffer from disabling hearing loss, Earlier studies have shown that persons with hearing loss…
- Trial name
- NCT05543148
- Testing
- Questionnaire
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sohag University