Clinical trials: Disability, Developmental
Developmental Delay
Comparing Two Protocols to Improve Reflex Integration and Functional Performance
The goal of this quantitative experimental study is to compare two occupational therapy interventions intended to improve functional skills.
- Trial name
- NCT05825248
- Testing
- Fine and gross motor treatment only, Reflex integration + fine and gross motor treatment
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Salus University
Autism Spectrum Disorder, Healthy
Differences in Prosocial Behaviors and Related Brain Networks in Children With Autism and Typical Development
The goal of this observational study is to compare the brain functional network between children with autism and typical development, using magnetic resonance imaging (MRI), electroencephalogram/event-related potentials(EEG/ERPs)…
- Trial name
- NCT06908174
- Testing
- ADOS-2
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Child Behavior Problem, Intellectual Disability
Determining the Effectiveness of Sexual Health and Development Education for Children With Intellectual Disability
By integrating sexuality and disability literatures, theories, and research, this study aims to: determine the effectiveness of sexual health and development education for children (12-18 years) with mild to moderate intellectual…
- Conditions
- Child Behavior Problem, Intellectual Disability, Sexuality
- Trial name
- NCT04635969
- Testing
- Sexual Health and Development Education for Children With Intellectual Disability
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Aylin KURT
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Autism or Autistic Traits, Mental Health Disorder
The Effects of Executive Functions and Social Cognition on Mental Health
The objective of this study is to analyze the effects of executive functions (EFs) and social-cognitive abilities on the associations between autistic traits and mental health indicators (depression, anxiety, and stress).
- Conditions
- Autism or Autistic Traits, Mental Health Disorder, Executive Dysfunction, Social Cognition
- Trial name
- NCT06213194
- Testing
- MindZone
- Where
- Turkey (Türkiye)
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Ibn Haldun University
Autism Spectrum Disorder
Emotional Skills Training with Social Robot
Autism is a neurodevelopmental disorder that involves difficulties especially in the sphere of social interaction, social communication, and restricted and stereotyped behavior patterns.
- Trial name
- NCT06179953
- Testing
- NAO intervention, Traditional intervention
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Neurodevelopmental Outcomes, ADHD - Attention Deficit Disorder With Hyperactivity
Where Wild Things Grow: Nature- and Activity-based Group Interventions for Neurodivergent Children and Youth
The goal of this action research project is to develop and implement nature- and activity-based group interventions across health care, school and leisure settings in Southern Norway.
- Conditions
- Neurodevelopmental Outcomes, ADHD - Attention Deficit Disorder With Hyperactivity, Autism, Tourette Syndrome
- Trial name
- NCT07203469
- Testing
- Universal approach, Selective approach, Outdoor therapy
- Where
- 2 sites in Norway
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Autism Spectrum Disorder, Autism
Efficacy of Reading Intervention on the Brain Connectivity in Autism
The overarching goal of this proposal is to test the impact of a comprehensive reading intervention program (Visualizing and Verbalizing) on changing the neurobiological mechanisms underlying reading comprehension deficits in…
- Conditions
- Autism Spectrum Disorder, Autism, Reading Problem
- Trial name
- BrainREAD (NCT05568056)
- Testing
- Visualizing and Verbalizing for Language comprehension and Thinking
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Autism Spectrum Disorder, Parents
Virtual Reality Experiences as Tools to Support Mental Health in Parents of Children With Autism
Mindfulness is a technique that involves the intentional and non-judgmental regulation of attention to the present moment, with curiosity, openness, and acceptance, as per its definition.
- Trial name
- Mind-VR (NCT05852795)
- Testing
- Virtual Reality-mediated Mindfulness-Based Interventions, Virtual Reality-mediated Mindfulness-Based Interventions without audio guided experience
- Where
- Italy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorder
Development and Evaluation of A Game-Based Mobile App for Increasing Physical Activity in Autistic Adults
The clinical study aims to develop and test a gamified mobile health app called PuzzleWalk (PW) to promote physical activity (PA) and reduce sedentary behavior (SB) in autistic adults, including those with mild intellectual…
- Trial name
- NCT06566131
- Testing
- Gamified mobile health app
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Autism Spectrum Disorder, Somatic Symptom Disorder
Somatic Symptoms in Autism Spectrum Disorder: Data Integration
Autistic patients have higher rates of co-morbid somatic symptoms. Thus, compared to the general population, they experience more health-related concerns, such as autoimmune disease, gastrointestinal disease, cardiovascular…
- Trial name
- NCT05886361
- Testing
- No intervention involved
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Fine Motor Skills, Occupational Performance
Effects of Virtual Reality-Based Interventions on Fine Motor and Activities of Daily Living Skills in Children Aged 5-10 Years With Autism Spectrum Disorder
This study will investigate the effects of a Leap Motion-based virtual reality intervention on fine motor skills and daily living performance in children aged 5-10 years with autism spectrum disorder (ASD).
- Conditions
- Fine Motor Skills, Occupational Performance, Virtual Reality (VR) Technology, Autism Spectrum Disorder
- Trial name
- VR-FAD (NCT07859345)
- Testing
- Leap Motion-Based Virtual Reality Intervention
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beyza Asli Bilsel
Developmental Disabilities, Psychological Wellbeing
90SecondParent Wellbeing: Weekly Health Letters for Parents of Children With Developmental Disabilities
Parents of children with developmental disabilities (DD) consistently report significant psychological distress, a vulnerability amplified during the COVID-19 pandemic due to intensified caregiving demands and reduced access to…
- Conditions
- Developmental Disabilities, Psychological Wellbeing, Parental Wellbeing
- Trial name
- NCT07869251
- Testing
- 90SecondParent Wellbeing
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Autism
Comprehensive Collection, Charting, and Communication System
As the prevalence of autism spectrum disorders continues to rise and the shortage of special education resources becomes more dramatic, the need for electronic tools that reduce the time burden of implementing an individual…
- Trial name
- CCCCSys (NCT01005953)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- SymTrend Inc.
Autism Spectrum Disorder, Apraxia of Speech
Video Assisted Speech Technology to Enhance Motor Planning for Speech
Nearly 3.5 million Americans are diagnosed with Autistic Spectrum Disorder (ASD), a communication disorder that causes skill limitations in the areas of language acquisition, sensory integration, and behavior.
- Trial name
- VAST (NCT04764539)
- Testing
- Video Assisted Speech Therapy (VAST)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- iTherapy, LLC
Autism Spectrum Disorder (ASD
Exploring the Physiological Mechanisms of Austism Through Organoids
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder affecting approximately 1% of the population, characterized by difficulties with social interaction and communication.
- Trial name
- EXPECT HYPE (NCT07494331)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder
AI-Based Reflective Parenting Simulation for Parents of Autistic Children
This randomized controlled trial evaluates an AI-based parental simulation designed to support reflective parenting, emotional regulation, and parent-child communication among parents of autistic children aged 3 to 12 years.
- Trial name
- NCT07687381
- Testing
- AI-Based Reflective Parenting Simulation
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Autism
Effects of Hyperbaric Oxygen Therapy on Children With Autism
PURPOSE The purpose of this investigation is to evaluate the cognitive and behavioral effects of Hyperbaric Oxygenation Therapy in children who present with a diagnosis of autism spectrum disorder. HYPOTHESIS 1.
- Trial name
- NCT00406159
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Thoughtful House
Relation, Mother-Child, Family Conflict
Children's Learning Centers Group FNI
The purpose of this study is to compare the effects of Family Nurture Intervention in a mother-child group setting with a Standard Children's Learning Center (CLC) Program for preschool-aged children (ages 2-4.5).
- Conditions
- Relation, Mother-Child, Family Conflict, Emotional Disturbances, Behavior Problem
- Trial name
- NCT03908268
- Testing
- Family Nurture Intervention (FNI), Standard Children's Learning Center (CLC) Program
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Columbia University
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.