Clinical trials: Disability, Evaluation
Physical Activity, Social Responsibility
Imitation-based Dog Assisted Intervention, for Children With Developmental Disabilities.
This R21 application will provide a multidisciplinary One Health approach to DAID physical activity intervention for adolescents with developmental disabilities and their family dog.
- Trial name
- NCT03462407
- Testing
- DAID, Dog walking
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Down Syndrome, Chromosome Abnormalities
Down Syndrome - Comparison of Screening Methods in the 1st and 2nd Trimesters
Too much or too little genetic information (chromosome material) can cause abnormal development of the fetus or death. Each year approximately 2.5 million pregnant women are screened for Down Syndrome using invasive screening…
- Trial name
- NCT00006445
- Testing
- Ultrasound, Serum screen
- Where
- 10 sites in United States
- Volunteers
- 38,000 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Rheumatoid Arthritis (RA)
Evaluation of Functional Disability in Rheumatoid Arthritis Patients
Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune inflammatory disease that mainly affects the joints and periarticular soft tissues.
- Trial name
- NCT07801261
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sohag University
Down Syndrome, Patau Syndrome
Clinical Evaluation of the IONA Test for Non-invasive Pre Natal Screening in Twin Pregnancies
The purpose of this study is to evaluate the performance of the IONA® test which is a non-invasive prenatal test (NIPT) for Down's syndrome and other chromosomal abnormalities in twin pregnancies, from a maternal blood sample.
- Conditions
- Down Syndrome, Patau Syndrome, Edward's Syndrome
- Trial name
- TWIN (NCT03200041)
- Testing
- Blood sample
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Premaitha Health
Fibromyalgia, Neck Pain
Kinesiophobia in Patients With Fibromyalgia Syndrome and Chronic Neck Pain
Kinesiophobia which is described as fear of movement reduces physical activity levels and increases the risk of chronic pain. The investigators consider that kinesiophobia levels are higher in patients with fibromyalgia syndrome…
- Conditions
- Fibromyalgia, Neck Pain, Healthy
- Trial name
- NCT03778801
- Testing
- kinesiophobia
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aksaray University Training and Research Hospital
Musculoskeletal System, Disability Evaluation
Perception of Musculoskeletal Injury in Professional Dancers
The annual frequency of injury among dancers has been reported to range between 23-84% while as many as 95% of professional dancers have ongoing pain.
- Conditions
- Musculoskeletal System, Disability Evaluation, Wounds and Injuries
- Trial name
- NCT00554957
- Where
- Canada
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Adults Without Disabilities
Normative Values and Reference Equations of a New Incremental Step Test for the Assessment of Exercise Capacity for Portuguese Adults
According to the official guidelines, a range of settings for cardiorespiratory rehabilitation, including the community- and home-based models, are considered to answer to the inadequate number of rehabilitation services…
- Trial name
- NCT04801979
- Testing
- Incremental Step Test
- Where
- Portugal
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Polytechnic Institute of Porto
Neck Pain, Neck Pain Musculoskeletal
Neck Musculoskeletal Symptoms Among Turkish Endodontists
This observational study aims to evaluate the prevalence, severity, and characteristics of neck musculoskeletal symptoms among Turkish endodontists.
- Conditions
- Neck Pain, Neck Pain Musculoskeletal, Musculoskeletal Assessment, Musculoskeletal Disorder of the Neck
- Trial name
- ENDO-NECK (NCT07516782)
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Atlas University
Down Syndrome, Amyloid Beta-protein
Phase II Study of Florbetaben (BAY94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid.
To determine the sensitivity of the visual assessment of BAY94-9172 PET images in detecting cerebral β-amyloid in individuals with Down Syndrome (DS) and specificity in individuals without DS.
- Trial name
- NCT00928304
- Testing
- Florbetaben (BAY94-9172)
- Where
- 2 sites in United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Lantheus Biosciences Ltd.
People With Motor Disabilities
Evaluation of Perceived Satisfaction With the Use of the Dreeft® Device in Real-life Situations
Functional, independent mobility is essential for everyone (Fasciglione, 2017). It determines everyone's ability to engage in activities of daily living and contributes to maintaining health and well-being (Fasciglione, 2017).
- Trial name
- PARA-DREEFT (NCT06524128)
- Testing
- Dreeft wheels (EPPUR company)
- Where
- 2 sites in France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape
Adaptation, Lumbar Stiffness
'Lumbar Stiffness Disability Index' Turkish Adaptation
Despite advancements in assessment and treatment methods, diagnosing and treating lower back pain remains challenging for researchers and clinicians.
- Trial name
- NCT06184776
- Testing
- Lumbar Stiffness Disability Index
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Sexual and Reproductive Health, Disability
Evaluation of a Disability-Focused Sexual and Reproductive Health Curriculum for Health Students in Tanzania
This randomized controlled trial will evaluate the efficacy of a three-day sexual and reproductive health curriculum focused on persons with disabilities and tailored to the Tanzanian context.
- Conditions
- Sexual and Reproductive Health, Disability, Health Knowledge, Attitudes, Practice, Health Education
- Trial name
- NCT07772778
- Testing
- Disability-Focused Sexual and Reproductive Health Curriculum
- Where
- Tanzania
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Pain
Kinesiotaping and Rigid Taping in Sacroiliac Joint Dysfunction
Objective: To evaluate the effects of rigid-taping and kinesiotaping (lymphatic correction) on pain, joint mobility and disability in patients with sacroiliac joint dysfunction (SIJD).
- Trial name
- NCT06907433
- Testing
- Kinesiotaping, Rigid taping, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Social Exclusion, Chronic Disease
Protocol for a Low Threshold Exercise Intervention for Women Experiencing Homelessness and Addiction.
Background: Frailty is a complex multi-dimensional state of increased vulnerability to adverse health outcomes and is usually associated with older age but there is growing evidence of accelerated ageing and frailty in…
- Conditions
- Social Exclusion, Chronic Disease, Physical Disability, Addiction
- Trial name
- LEAP-W (NCT06264895)
- Testing
- Exercise
- Where
- Ireland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Intellectual Developmental Disorder
Emotional Processes in Adults With Intellectual Developmental Disorder
Emotions play a crucial part in the quality of life, interpersonal relationships and mental health in general. In adults presenting with intellectual developmental disorder (IDD), emotional abilities may be hindered, thus leading…
- Trial name
- EmoTDI (NCT07303270)
- Testing
- ACQUISS protocol assessing emotional processing.
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Pregnancy
Assessment of Women's Insight and Understanding of Down's Syndrome Screening by Non-invasive Prenatal Testing (NIPT) During Their First Ultrasound
Down's syndrome is the leading cause for mental retardation in France. Screening for this chromosomal abnormality is systematically proposed during pregnancy.
- Trial name
- DEPIST21 (NCT03549286)
- Testing
- Questionnaire passation
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
People With Subjective Cognitive Impairement (SCI)
Physical Activity Component of the Greek Interventional Geriatric Study to Prevent Cognitive Impairment and Disability (GINGER)
The Greek Interventional Geriatric Study to Prevent Cognitive Impairment and Disability (GINGER) is a six-month multimodal, multicenter study aimed at people with Subjective Cognitive Impairement (SCI).
- Trial name
- GINGER (NCT06528379)
- Testing
- Physical Activity
- Where
- 2 sites in Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Patras
Developmental Dyslexia, Developmental Language Disorder
Dynamic Assessment of the Risk for Language and Reading Disorders in Monolingual and Multilingual Children
The project represents the completion of a part of the recently concluded European project MultiMind, in which a computer platform called MuLiMi was developed and validated.
- Trial name
- NCT06937255
- Testing
- computerized Dynamic Assessment
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Cerebral Palsy and Healthy Individuals
Transcultural Validation of Activities Scale for Kids (ASK)
The Activities Scale for Kids performance (ASKp) is one of the few self-assessment questionnaires in pediatric rehabilitation that measures child perception in performance of daily routine activities.
- Trial name
- NCT03325842
- Testing
- ASKp
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Microcephaly, Mental Retardation
Neurodevelopment Outcome of Newborns Exposed to Zika Virus (ZIKV) in Utero
This prospective cohort study will determine the natural history of fetal exposure to Zika virus (ZIKV) and its effects on the fetus and newborn with emphasis on neurodevelopment outcome.
- Trial name
- ZENI (NCT02943304)
- Testing
- Symptomatic pregnant women with positive RT-PCR ZIKV in serum or urine, or a positive serologic test specific for ZIKV
- Where
- Colombia
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Universidad Industrial de Santander