Clinical trials: Disc Herniations
Lumbal Disc Herniation, Capacitive and Resistive Electric Transfer Therapy
Tecar Therapy in Lumbar Disc Herniation
This randomized controlled trial investigates the effects of Tecar therapy on pain intensity and functional status in patients with lumbar disc herniation.
- Conditions
- Lumbal Disc Herniation, Capacitive and Resistive Electric Transfer Therapy, Exercise Training
- Trial name
- LDH-TECAR (NCT07082660)
- Testing
- High-Frequency Capacitive-Resistive Diathermic Current Therapy (TECAR), Lumbal Stabilization Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Şebnem Nur Alkan
Degenerative Disc Disease, Herniated Disc
Bone Graft Materials Observational Registry
A multi-center, prospective, observational patient registry to collect information on the clinical outcomes and "real world" use of approved and commercially available bone graft substitutes, autograft and allograft.
- Conditions
- Degenerative Disc Disease, Herniated Disc, Spinal Stenosis, Spondylolithesis
- Trial name
- APPROACH-001 (NCT00974623)
- Testing
- Bone graft substitute, autograft or allograft
- Where
- 14 sites in United States, Hungary and 1 more
- Volunteers
- 329 people
- Sponsor
- Baxter Healthcare Corporation
Intervertebral Disc Disease, Lumbar Disc Disease
A Study of SI-6603 in Patients With Lumbar Disc Herniation
The purpose of this study is to evaluate the efficacy and safety of SI-6603 (condoliase) in patients with lumbar disc herniation.
- Trial name
- NCT01941563
- Testing
- Condoliase
- Where
- 32 sites in United States
- Volunteers
- 385 people
- Sponsor
- Seikagaku Corporation
Spinal Stenosis, Intervertebral Disc Displacement
Tranexamic Acid in Reducing Gross Hemorrhage and Transfusions of Spine Surgeries
Multilevel decompression and bone graft fusion is a most effective measure for treating degenerative lumbar spinal diseases. Yet, the surgery is commonly associated with large amount of perioperative blood loss and high demand…
- Trial name
- TARGETS (NCT03011866)
- Testing
- Wound topically irrigated with 500mg TXA, 1mg/kg/hr TXA intravenous infusion till the last suture
- Volunteers
- 176 people
- Sponsor
- Peking Union Medical College Hospital
Intervertebral Disc Displacement, Intervertebral Disc Degeneration
Lumbar Disc Space Height in Young Disc Herniation and Degeneration Patients
As low back pain (LBP) imposes a heavy socioeconomic burden, early detection of pathologic intervertebral disc change in young adults holds high clinical relevance as a common structural cause of LBP.
- Conditions
- Intervertebral Disc Displacement, Intervertebral Disc Degeneration, Low Back Pain
- Trial name
- NCT02351206
- Testing
- x-ray, MRI
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Jaseng Hospital of Korean Medicine
Radiculopathy Lumbar, Low Back Pain
Evaluation of Transforaminal Epidural Steroid Injection in Radicular Low Back Pain According to MSU Classification
Low back pain is a common disease in all ages and it effects seriously quality of life. Medical treatment,interventional methods and surgery are the treatment options.
- Conditions
- Radiculopathy Lumbar, Low Back Pain, Disc Herniation, Injections, Epidural
- Trial name
- NCT06275529
- Testing
- Transforaminal Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Lumbar Radiculopathy, Lumbar Disc Herniation
Pentoxifylline and Lumbar Radiculopathy
The objective of this prospective controlled crossover study is to evaluate the efficacy and safety of pentoxifylline per os (800 mg daily) in the management of lumbar radiculopathy
- Conditions
- Lumbar Radiculopathy, Lumbar Disc Herniation, Lumbar Disc Disease
- Trial name
- NCT03060434
- Testing
- Pentoxifylline Oral Tablet, Ibuprofen
- Where
- Lebanon
- Volunteers
- 67 people
- Sponsor
- St Joseph University, Beirut, Lebanon
Lumbar Disc Herniation Surgery
Virtual Reality Operating Room Tour and Preoperative Anxiety in Spinal Surgery Patients Experimental: "VR Operating Room Tour" - Participants Viewed a Five-minute Virtual Reality Video of Preoperative Preparation and the Operating Room the Night Before Surgery, Facilitated by a Nurse.
This randomised controlled trial evaluated whether a nurse-facilitated virtual reality (VR) tour of the operating room reduces preoperative anxiety in adults awaiting lumbar disc herniation surgery.
- Trial name
- VROOM (NCT07778030)
- Testing
- Virtual Reality Operating Room Tour
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Zonguldak Bulent Ecevit University
Lumbar Disc Herniation
THE EFFECT OF RELAXATION EXERCİSE ON COMFORT AND ANXIETY IN HERNIATED LUMBAR DISC SURGERY
This study aimed to investigate the effect of progressive relaxation exercises on the comfort and anxiety levels of patients undergoing lumbar disc herniation surgery in the neurosurgery clinic.
- Trial name
- NCT06688773
- Testing
- Progressive relaxation exercise, Control group: Standart nursing care group
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Bandırma Onyedi Eylül University
Lumbar Disc Herniation, Lumbar Disc Surgery
Effectiveness of Virtual Reality-Assisted Physical Therapy in the Acute Phase After Lumbar Disc Surgery
The goal of this clinical trial is to evaluate the effectiveness of virtual reality-assisted physical therapy in the acute postoperative period after lumbar disc surgery.
- Trial name
- NCT07204197
- Testing
- Virtual Reality-Assisted Physical Therapy, Conventional Physical Therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Hacettepe University
Lumbar Spinal Stenosis, Lumbar Disc Herniation
In Turkish Version Lumbar Spine Surgery Expectation Survey
The aim of this study was to determine the Turkish validity and reliability of Lumbar Spine Surgery Expectations Survey developed by Mancuso.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Radiculopathy, Lumbar Fracture
- Trial name
- NCT04547075
- Testing
- Turkish validity and reliability
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Kutahya Health Sciences University
Lumbar Spine Disc Herniation
Lumbar Segmental Stabilization and TENS in Lumbar Disc Herniation
The purpose of this study was to compare the efficacy of method Lumbar Segmental Stabilization and transcutaneous electrical nerve stimulation (TENS) on pain, functional disability and ability to activate the transversus…
- Trial name
- NCT01640431
- Testing
- Lumbar stabilization exercises
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Lumbar Disc Herniation, Low Back Pain
Effect of Neurodynamic Mobilization in Patients With Lumbar Disc Herniation
The objective of this randomized controlled trial was to investigate the effects of neurodynamic mobilization on pain intensity, normal joint motion, neurodynamics, functional level, and disability in patients with lumbar disc…
- Trial name
- NCT07203560
- Testing
- Neurodynamic Mobilization, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Aydin Adnan Menderes University
Lumbar Disc Herniation
Non-pharmacological Treatment vs Pharmacological Treatment for Non-acute Lumbar Disc Herniation
This is a randomized controlled study comparing non-pharmacological treatment to proactive pharmacological treatment for patient with non-acute lumbar disc herniation with moderate or higher levels of pain.
- Trial name
- NCT06024460
- Testing
- non-pharmacological treatment strategy, pharmacological treatment strategy
- Where
- 4 sites in South Korea
- Volunteers
- 200 people
- Sponsor
- Jaseng Medical Foundation
Lumbar Disc Herniation, Percutaneous Endoscopic Lumbar Discectomy
Randomized Controlled Clinical Study of Biplanar Ultrasound-guided Puncture of Lumbar Interforamen
The goal of this clinical trial is to compare Xplane ultrasound with radiography for guidance of lumbar interforamen puncture in patients with lumbar disc herniation.
- Conditions
- Lumbar Disc Herniation, Percutaneous Endoscopic Lumbar Discectomy, Three-dimension Ultrasound, Learning Curves
- Trial name
- NCT06315803
- Testing
- Real-time 3D Xplane ultrasound
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Yi Mao
Disc Herniation
Intradural Disc Herniation: a Case Report and Review of Complications
This observational study collects clinical data as well as pathological reports from a patient with an intradural disc herniation, reports on the course of the patient's recovery through surgical treatment, summarizes the…
- Trial name
- NCT06141551
- Testing
- total laminectomy decompression
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Gansu Provincial Hospital
Disk, Herniated
A Pilot Study of the InterCushion Disc Nucleus Prosthesis (DNP) in Patients Receiving Discectomy
The primary endpoints of the investigation will include assessment of the maintenance of disc height demonstrated by radiographic evidence based on plain radiographs and MRI and relief of pain as measured by Visual Analog Scale…
- Trial name
- NCT01652053
- Testing
- Disc Nucleus Replacement (InterCushion DNP)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Vertebral Technologies, Inc.
Type 2 Diabetes (T2DM), Hyperglycemia
CGM-Based Glycemic Analysis After ESI
The goal of this clinical study is to learn how blood glucose levels change after an epidural steroid injection (ESI) with dexamethasone in adults.
- Conditions
- Type 2 Diabetes (T2DM), Hyperglycemia, Radicular Pain, Spinal Stenosis
- Trial name
- CGMSteroid (NCT07280780)
- Testing
- Epidural Steroid Injection, Continuous Glucose Monitoring
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Korea University Anam Hospital
Disk Herniated Lumbar, Coordination Lack
The Effect of Abdominal Hallowing on Coactivation of Lower Extremity Muscles in Patients With Lumbal Disc Herniation
Intervertebral disc degenerations are the most important cause of chronic low back pain resulting in job loss and associated socio-economic problems in developed and developing industrial countries 1.
- Conditions
- Disk Herniated Lumbar, Coordination Lack, Muscle Weakness
- Trial name
- NCT05233254
- Testing
- Abdominal Hollowing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Hacettepe University
Chronic Ankle Injuries, Chronic Low-back Pain
Ankle Spine Syndrome "RAFFET Syndrome II
A case series aimed to describe a new clinical condition for the first time in the medical literature called Ankle Spine Syndrome or "RAFFET Syndrome II".
- Conditions
- Chronic Ankle Injuries, Chronic Low-back Pain, Lumbar Disc Herniation, Calf Muscle Weakness
- Trial name
- NCT06140862
- Testing
- calf muscle strengthening and streching
- Where
- Egypt
- Volunteers
- 1,000 people
- Sponsor
- Noha Khaled Shoukry